No abstract available.
Bleomycin* ; Warts*

BACKGROUND: The main function of melanocyte is known to proiect the skin from hazardous sun-light. But, some investigators have claimed lately that melanocytes are also related to the immunologic role in the epidermis becauase these cells produce IL-1 activity and IL-lb convertase activity, in vitro. OBJECTIVE: Our purposee were to investigate the effects of rIFN-b on the proliferation of melanocytes, melanin content, and the expression of HLA-DR aritign on melanocytes after a rIFN-y exposure. MEHTODS: The number of melanocytes, the melanin content, and the expression of HLA-DR antigen were evaluated on culturect human melanocytes according to a time sequence and various concentrations of rIFN-y. RESULTS: Antiproliferative activity on melanocytes was dependent on the exposure time and the concentration of rIFN-r. According to the exposure time and the concentration of rIFN-r, melanogenic activity was inhibited or stimulated, Normal melanocytes didnt express HLA-DR antigen, but when normal melanocytes were exposed to rIFN-r, the expression of HLA-DR antigen increased in a timeand concentration-dependent fashion. After the removal of rIFN-r fiom the culture media the expression of HLA-DR antigen on melanocytes also disappeared. CONCLUSION: In our study, melanocytes seem to be related to the irnmunologic role in the epidermis because these cells expressed HLA-DR antigen after rIFN-r exposue and we think that study could help to investigate between melanocytes and immunalogic mechanisms in various inflammatory skin diseases.
Culture Media ; Epidermis ; HLA-DR Antigens ; Humans* ; Interleukin-1 ; Melanins ; Melanocytes ; Research Personnel ; Skin ; Skin Diseases

No abstract available.
Female ; Ovary* ; Teratoma*

No abstract available.
Appendicitis*

We investigated the distribution of S-100 protein positive dendritic cells in the skin lesions with tuberculoid sturcture. For this study, we selected the paraffin blocks of biopsied specimens with the characteristic histopathology of lupus vulgaris (5cases), tubereulosis verrucosa cutis (1 case), lupus milaris disseminatus faciei (4 cases), and erythema induratum (7 cases). The cells were identified by immunohistochemical demonstration in paraffin sections. The results were as follows: 1. S-100 protein positive dendritic cells were regularly visualized in all lesions examined. 2. S-100 protein positive dendritic cells appeared usually between the lymphohistiocytic infiltrates around the tuberculoid granulomas in contrast to the cells of monocyte-macrophage system which were within the granulomas. And they appeared occasionally (e.g. in a case of lupus vulgaris) between epitheloid cells in the granulomas. 3. S-100 protein positive dendritic cells were more numerous in the granulomatous lesions which showed the well-formed tuberculoid sturcture. From these results, we suggested the S-100 protein positive dendritic cells act as accessory cells in the pathogenesis of the granulomatous lesions by the delayed type hypersensitivity.
Dendritic Cells* ; Erythema Induratum ; Granuloma ; Hypersensitivity ; Lupus Vulgaris ; Paraffin ; S100 Proteins ; Skin*

Recently, the incidence of pelvic bone fractures has been increased with increment of the volume of traffic. We reviewed 318 cases of pelvic bone fractures treated at the department of orthopaedic surgery of Hanyang University Hospital during the period from May, 1972 to December, 1980. The age and sex distribution, cause and classification of fractures, type of treatment, associated injuries and complications were recorded and investigated. The results obtained were as follows: 1. There were one hundred and ninety four (61%) male and one hundred and twenty four (39%) female, and one hundred and ninety seven patients (62%) in this entire series were aged from twenties to forties. The most common victims were in active persons. 2. The most common causative injury was traffic accident. 3. Two hundreds and thirteen (67%) cases were stable fracture and one hundred and five (33%) cases were unstable fracture, which were classified by Kanes classification. 4. The fracture of the femur was most commonly associated bone and joint injuries and the injury of the lower urinary tract was also most commonly associated soft tissue injuries. 5. All of the cases, except 3 cases of the avulsion fracture, were treated with conservative treatment. The remaining 3 cases were treated with surgical treatment, 6. The mortality rate was 5.3%, and the most common cause of death was hemorrhagic shock in 70.6% of the entire fatal cases in this series.
Accidents, Traffic ; Cause of Death ; Classification ; Clinical Study ; Female ; Femur ; Humans ; Incidence ; Joints ; Male ; Mortality ; Pelvic Bones ; Sex Distribution ; Shock, Hemorrhagic ; Soft Tissue Injuries ; Urinary Tract

No abstract available.
Adipose Tissue* ; Apoptosis ; Lipodystrophy*

No abstract available.
Epidermal Cyst

No abstract available.
Korea* ; Mercury Poisoning*

No abstract available.
Solvents*