1.A Study of Tibio
Kwang Hoe KIM ; Kwang Min WEE ; Byoung Inn CHANG
The Journal of the Korean Orthopaedic Association 1984;19(5):777-783
The object of this study was 336 Korean patients with degenerative arthritic knees and 1000 Koreans with normal knees who had visited the department of orthopaedic surgery of Hanyang University hospital during the period fmm January, 1980 to June, 1981. The purpose of this study was to investigate the changes of tibio-femoral angles and metaphysealdia physeal angles in response to the degenerative changes of the knees. By the roentgenogram, tibio-femoral angles and metaphyseal-diaphyseal angles were measured and those angles were analized statistically. The results were as follows 1. In young age group, the incidence of the degenerative arthritic knees was more frequent in male than in female. However, in the middle and older age groups, the incidence was higher in female than in male. 2. The mean value of tibio-femoral angle of the degenerative arthritic knees was −3.41°±0.22. It was about 1° varus compared with the normal mean value of −4.46°±0.27. The mean value of tibio-femoral angle in normal Korean was reduced appmximately 3°±5°valgus compared with the Westem normal peoples: 3. In general, the valgus tendency appeared a little more in the knees of female than in those of male. 4. The varus tendency was in pmportion to the degree of the aggrevation of the degenerative arthritis in the knees. 5. The mean value of metaphyseal-diaphyseal angle in normal Korean was 3.53°±0.24. It was 3°–4° varus compared with the Western normal peoples. 6.The varus was increased more in the standing position, in the state of weight bearing position, than in the supine position.
Female
;
Humans
;
Incidence
;
Knee
;
Male
;
Osteoarthritis
;
Posture
;
Supine Position
;
Weight-Bearing
2.Generation and Characterization of Anti - Human CTLA - 4 Monoclonal Antibodies.
Chang Yuil KANG ; Kwang Mi KIM
Korean Journal of Immunology 1997;19(4):447-454
No abstract available.
Antibodies, Monoclonal*
;
Humans*
3.Depression and anxiety of the inpatients with schizophrenia.
Kwang Cheol CHANG ; Min Cheol PARK
Journal of Korean Neuropsychiatric Association 1992;31(3):512-522
No abstract available.
Anxiety*
;
Depression*
;
Humans
;
Inpatients*
;
Schizophrenia*
4.A study on Serum Calcium, Phosphorus, Magnesium and Parathyroid Hormone Levels of Cord Blood in Newborn.
Journal of the Korean Pediatric Society 1986;29(2):45-51
No abstract available.
Calcium*
;
Fetal Blood*
;
Humans
;
Infant, Newborn*
;
Magnesium*
;
Parathyroid Hormone*
;
Phosphorus*
5.Histologic and Clinical Characteristics of Skin Warts According to the Human Papillomavirus Antigen Expression.
Kun Chang SONG ; Kwang Gil LEE
Korean Journal of Pathology 1993;27(4):379-386
Skin wart is an infectious disease of human papillomavirus(HPV). Its clinical and histopathologic characteristics are largely determined by lesion sties, viral type and host immunity. The infected basal cells and keratinocytes of the epidermis are induced to proliferate by the viral genome. It is, however, not well known how htose factors give rise to histopathologic alterations in the infected basal cells and keratinocytes. So, evaluation of correlation between HPV antigen expression in the wart tissues and clinical and histopathologic charateristics was done on 83 cases of skin warts. The age of patients ranged from 2 to 83 years. Thirty six(43.3%) cases were diagnosed before the age of third decade. The sex ratio was nearly same. Verruca vulgaris was most common(46 cases), followed by verruca plana(26 cases) and verruca palmoplantaris(11 cases). HPV antigen expression was observed in 43 out of total 83(51.8%). It was noted in 47.8%(22/46) of verruca vulgaris, in 46.2%(12/26) of verruca plana and in 81.8%(9/11) of verruca palmoplantaris. HPV antigen-positive groups included more younger patient's age and more higher PCNA than those of HPV negative groups. HPV positive groups also tend to have shorter duration of disease and more numerous mitoses than HPV negative groups. HPV antigen-positive groups showed lower inflammation grade than that of HPV negative groups(p<0.05). The higher the inflammaton grade is, the lower the HPV antigen expression rate. In summary, HPV antigen expression in cutaneous wart tissue is significantly correlated with the proliferative activity of the lesion. It is also significantly correlated with the inflammation that is considered to be the result of cell-mediated immune reaction.
Humans
6.Production of IL - 6 and IL - 8 in Human Fibroblasts Stimulated with Mycoplasma Lysates and Bacterial Toxins.
Kwang Hyuk KIM ; Myung Woong CHANG
Journal of the Korean Society for Microbiology 1999;34(6):573-582
Cytokines are hormone-like proteins which mediate and regulate inflammatory and immune responses. The purpose of this study was to investigate the effect of lipopolysaccharide (LPS), Staphylococcus enterotoxin B (SEB), and Mycoplasma lysates on regulation of IL-6 and IL-8 production by human nasal fibroblasts. Primary cultured cells were incubated with LPS (1.0 ug/ml) from E.coli, SEB (1.0 ug/ml) from S.aureus, or Mycoplasma lysates (M.pneumoniae, Mp; M. fermentans, Mf; M. hominis, Mh, each 1.0 ug/ml). The culture supernatants were collected at 2, 6, and 24 hr and assessed for IL-6 and IL-8 production by enzyme-linked immunosorbent assay. The production of IL-6 in the culture supematant was downregulated by LPS, SEB, or Mycoplasma lysates. But IL-6 was upregulated by mixed exposure with Mp+LPS (2 hr), Mp+LPS+SEB (24 hr), Mf+LPS (24 hr), Mf+LPS+SEB (2 hr), Mh+LPS (24 hr), Mh+SEB (24 hr), or Mh+LPS+ SEB (24 hr). The production of IL-8 in the culture supematant was similar to that of IL-6 by same stimulants. But IL-8 was upregulated by mixed exposure with Mf+LPS+SEB (2 hr), Mh+LPS (24 hr), Mh+ SEB (24 hr), or Mh+LPS+SEB (24 hr). These studies show that costimulation of LPS or SEB with Mycoplasma whole cell lysates upregulates the production of IL-6 and IL-8.
Bacterial Toxins*
;
Cells, Cultured
;
Cytokines
;
Enterotoxins
;
Enzyme-Linked Immunosorbent Assay
;
Fibroblasts*
;
Humans*
;
Interleukin-6
;
Interleukin-8
;
Mycoplasma*
;
Staphylococcus
7.Detection of contaminated mycoplasmas on the cultured cell lines.
Myung Woong CHANG ; Kwang Hyuk KIM
Journal of the Korean Society for Microbiology 1993;28(3):209-221
No abstract available.
Cells, Cultured*
;
Mycoplasma*
8.Case report on human infection of Hymenolepis diminuta.
The Korean Journal of Parasitology 1966;4(2):41-44
There has been no report on human infection of Hymenolepis diminuta in Korea until the first 3 cases were reported by our members after the identification of those eggs in stool in 1964. However, the distinct differentiation between H. diminuta and H. nana would often be difficult by the shape of eggs without adult worm. In 1965, authors found the additional case revealed the eggs in stool and succeeded to obtain three adult worms of H. diminuta from 10 years old boy in Pusan. The characteristic morphology of egg and adult worm were discussed to compare to those of H. nana. Conclusively, the first human infection of H. diminuta in Korea was reported after the identification both the eggs and adults worms
parasitology-helminth-cestoda
;
Hymenolepis diminuta
;
case report
9.Fine needle aspiration cytology of giant cell tumor of the rib-report of a case-.
Kun Chang SONG ; Kwang Gill LEE
Korean Journal of Cytopathology 1993;4(1):70-73
No abstract available.
Biopsy, Fine-Needle*
;
Giant Cell Tumors*
;
Giant Cells*
10.Photoelastic stress analysis on the supporting tissue of mandibular distal extension removable partial denture with various design of direct retainers.
Chang Ho LEE ; Kwang Nam KIM ; Ik Tae CHANG
The Journal of Korean Academy of Prosthodontics 1992;30(2):203-224
No abstract available.
Denture, Partial, Removable*