No abstract available.
Cushing Syndrome*

This study was performed to investigate the effect of octreotide on the contractility of rat vas deferens. The -smooth muscle strips isolated from the prostatic portion were myographied in isolated organ bath. Electric -field stimulation (monophasic square wave, duration : 1. mSec, voltage : 50 V, frequency : 5 Hz or 30 Hz, train : 10 Sec) produced reproducible contraction. The contraction was composed of two component, first phasic component (FPC) and second tonicc component (STC).. These contractions were abolished by -tetrodotoxin (1 microM). Octreotide inhibited the field stimulation induced contractions both FPC and STC concentration- dependently. The FPC was decreased by a desentization of purinergic receptor by pretreatment of mATP, and the STC was decreased by pr,,creatment of reserpine (3 mg/kg, EP) 24 hours before experiments. Octreotide reduced the field stimulation induced contraction in the presence of mATP and of reserpinized muscle strips. The inhibitory effect of octreotide was more potent at 5 Hz than at 30 Hz. Octreotide did not affect basal ton and exogenous norepinephrine- or ATP-induced contraction. These results suggest that octreotide inhibit the contractility of the isolated rat vas deferens by inhibition of the release of neurotransmitters, both ATP and norepinephrine from adrenergic nerve terminal.
Adenosine Triphosphate ; Animals ; Baths ; Neurotransmitter Agents ; Norepinephrine ; Octreotide* ; Rats* ; Reserpine ; Vas Deferens*

PURPOSE: The purpose of this study was to examine differences in awareness and practice of oral health care in pregnant women with and without oral health care education experience. METHODS: Participants in the survey for this study were 221 pregnant women in female exclusive hospitals located in B city and G city. Data were collected from October to December, 2014 using self-report structured questionnaires and analyzed using SPSS/Win 21.0 program. RESULTS: The number of pregnant women experienced in oral health education was 36.2%. The oral health care awareness of pregnant women experienced in oral health education total score was 15.14±1.96, and inexperienced pregnant women total score was 14.14±2.63 (t=3.26, p=.001). The oral health care practice of pregnant women experienced in oral health education total score was 12.90±2.48, and inexperienced pregnant women total score was 10.95±4.06 (t=3.89, p<.001). The relationship between the awareness and practice of oral health care was positively correlated. CONCLUSION: Based on this study outcomes, considering the importance for oral health education in the antenatal care program when the pregnant women visiting the hospital for medical check-up.
Education* ; Female ; Humans ; Oral Health* ; Pregnant Women*

Carbapenem resistance is a serious clinical and public health threat. Carbapenemase can confer carbapenem resistance, and most carbapenemase genes are plasmid encoded so resistance can easily spread. In this study, we aimed to develop a novel system based on the TaqMan platform for the rapid detection of 6 clinically prevalent carbapenemase genes: Klebsiella pneumoniae carbapenemase, New Delhi metallo-β-lactamase, oxacillinase, imipenem-hydrolyzing, Verona integron-encoded metallo-β-lactamase, and Guiana extended-spectrum β-lactamase.

No abstract available.
Lung* ; Neoplasm Metastasis* ; Sarcoma* ; Thorax*

The epidural injection on morphine is an effective method for postoperative pain management. The associated side effects have, however, precluded its widespread use in a variety of clinical settings. Intrathecal administration of morphine incurs a high incidence of pruritus, nausea and vomiting, somnolence, urinary retention and life-threatening respiratory depression in severe cases. We report here one case of accidental total spinal anesthesia with lidocaine, followed by intrathecal injection of morphine. A 39-year-old female with an ovarian tumor was scheduled for a total abdominal hysterectomy under epidural anesthesia. After the epidural space was identified erroneously, 20 ml of 2% lidocaine mixed with 1:200,000 epinephrine was administered into the epidural space, immediately followed by injection of morphine 3 mg. All signs of a total spinal block were observed. She was then intubated and her respiration was controlled without delay. The schedulled operation was carried out uneventfully for 1 hour and 20 minutes. In the recovery room, a bolus injection of naloxone 0.4 mg was performed for prevention of respiratory depression. Dripping of naloxone 0.4 mg/100 ml/hour was continued for 20 hours postoperatively. However, her respiratory rate started to be decreased to 9/min around 8 hours after the surgery so that naloxone 0.2 mg was again injected intravenously. Headache and other side effects were not observed. The patient was out of ICU and discharged on the 6th postoperative day.
Adult ; Anesthesia, Epidural ; Anesthesia, Spinal* ; Epidural Space ; Epinephrine ; Female ; Headache ; Humans ; Hysterectomy ; Incidence ; Injections, Epidural ; Injections, Spinal ; Lidocaine ; Morphine* ; Naloxone ; Nausea ; Pain, Postoperative ; Pruritus ; Recovery Room ; Respiration ; Respiratory Insufficiency ; Respiratory Rate ; Urinary Retention ; Vomiting

A case of multiple myeloma with massive pleural effusion is reported. A 53 year-old previous known multiple myeloma patient vistited our hospital complaining of cough with sputum. Radiologic study revealed multiple osteolytic bony lesions and left side pleural effusion. The effusion were bloody exudates containing numerous atypical plasma cells. The tumor cells showed pleomorphism, eccentric nuclei, prominent nucleoli, perinuclear halo, multincleation, and chromatin patterns of occasional cart-wheel appearance. The cytological examination of pleural fluid established the malignant nature of the effusion with multiple myeloma.
Biopsy* ; Chromatin ; Cough ; Enzyme Assays* ; Exudates and Transudates ; Glycogen Storage Disease* ; Glycogen* ; Humans ; Lung ; Lymphoma, T-Cell, Peripheral ; Middle Aged ; Multiple Myeloma ; Plasma Cells ; Pleural Effusion ; Sputum

In the present study, patients were traumatized with muscle-crushing injuries, or they were non-traumstized. The plasma concentration of potassium and sodium were measured before the induction of anesthesia and at selected intervals after the administration of succinylcholine(SCC) in some patients were inhaled the beta2-agonist, salbutamol (about 800 ug) via an endotracheal tube and in the others were not given it. There was no significant difference in the base lines of potassium and sodium between the traumatized and nontraumatized patients. Salbutamol diminished the rise of potassium(-0.30 to 0.09 mEq/L) but did not affect the plasma sodium level. There was no significant side-effect of this agent, but sinus tachycardia was the only thing noted. These results are consistent with the proposed mechanism that the decrease in serum potassium due to salbutamol is most likely a shift of potassium ions from the extracellular space to the intracellular space. Inhalation of salbutamol may be a useful method for the prevention of SCC induced hyperkalemia without any serious side-effect in patients with preexisting hyperkalemia properties who have gone through traums.
Albuterol* ; Anesthesia ; Extracellular Space ; Humans ; Hyperkalemia* ; Inhalation ; Intracellular Space ; Ions ; Plasma ; Potassium ; Sodium ; Succinylcholine* ; Tachycardia, Sinus

The accidental swallowing of foreign body is a common problem in the children. We describe the case of 37-month-old girl in whom a gastric ulcer was caused by the ingestion of three magnets. This case report demonstrates that if more than one magnet were swallowed, they should be removed even if there are no sharp edges and small size. Because the magnets will attract each other and hold the intestinal walls between them, causing necrosis and resulting in intestinal perforation or a fistula.
Child ; Child, Preschool* ; Deglutition ; Eating* ; Female* ; Fistula ; Foreign Bodies ; Humans ; Intestinal Perforation ; Necrosis ; Stomach Ulcer*

We report two cases of supratentorial gangliocytomas mimicking an extra-axial tumor. MR imaging indicated that the tumors were extra-axial, and meningiomas were thus initially diagnosed. Relative to gray matter, the tumors were hypointense on T1-weighted images and hyperintense on T2-weighted images. On contrast-enhanced T1-weighted images, homogeneous enhancement was observed, while CT scanning revealed calcification in one of the two cases.
Adult ; Brain Neoplasms/*diagnosis/pathology ; Case Report ; Female ; Ganglioneuroma/*diagnosis/pathology ; Human ; *Magnetic Resonance Imaging ; Middle Age