1.Effects of MK-801, CNQX, Cycloheximide and BAPTA-AM on Anoxic Injury of Hippocampal Organotypic Slice Culture.
Soo Hyeon MOON ; Taek Hyon KWON ; Youn Kwan PARK ; Heung Seob CHUNG ; Jung Keun SUH
Journal of Korean Neurosurgical Society 2000;29(8):1008-1018
No abstract available.
6-Cyano-7-nitroquinoxaline-2,3-dione*
;
Cycloheximide*
;
Dizocilpine Maleate*
2.Laparoscopic Nephrectomy for Tuberculous Kidney.
Hyeon Hoe KIM ; Kyu Sung LEE ; Kwan Jin PARK ; Han Jong AHN
Korean Journal of Urology 2000;41(4):554-559
No abstract available.
Kidney*
;
Nephrectomy*
3.Experience of Transperitoneal Laparoscopic Adrenalectomy: lnitial 4 Cases.
Ahn Kie LEE ; Kwan Jin PARK ; Hyeon Hoe KIM ; Hwang CHOI
Korean Journal of Urology 2000;41(3):408-413
No abstract available.
Adrenalectomy*
4.Cervical Intramedullary Cysticercosis: Case Report.
Hyeon Dong JANG ; Kwan Ho PARK ; Jung Chul KIM
Journal of Korean Neurosurgical Society 2003;33(3):323-325
Spinal intramedullary cysticercosis is a rare manifestation of neurocysticercosis and may present as a isolated lesion. We report a case of cervical intramedullary cysticercosis in a 57-year-old man. The patient presented with weakness, numbness of the right upper extremity, and urinary difficulty. Magnetic resonance images demonstrated a round cystic lesion at the C4-5 level. We performed C4-5 laminectomy with total removal of intramedullary cystic lesion. Diagnosis was confirmed by histopathological examination. The patient was given albendazole(15mg/kg/day for 30 days) along with corticosteroid.
Albendazole
;
Cysticercosis*
;
Diagnosis
;
Humans
;
Hypesthesia
;
Laminectomy
;
Middle Aged
;
Neurocysticercosis
;
Spinal Cord
;
Upper Extremity
5.Antioxidants in Serum and Induced Sputum of COPD Patients.
Hyeon Kwan PARK ; Young Kwon YU ; Kyu Sik KIM ; Sung Chul LIM ; Young Chul KIM ; Kyung Ok PARK
Tuberculosis and Respiratory Diseases 2001;50(2):158-170
BACKGROUND: Although an oxidants and antioxidants imbalane has been considered in the pathogenesis of chronic obstructive pulmonary disease (COPD), there is a paucity of reports focussing on the smoking-induced changes of oxidants and antioxidants in COPD. METHOD: The concentration of antioxidants (ascorbic acid, uric acid, retinol, and α- &γ-tocopherol) was measured in the serum and induced sputum of 30 healthy controls and 34 stable COPD patients using high performance liquid chromatography (HPLC). The inhibition of lipid peroxidation as an index of antioxidant capacity was measured in the serum by a TBA assay. RESULTS: The serum concentration of ascorbic acid, α-tocopherol, and retinol were significantly lower in the patients with COPD than in healthy controls (484.8±473.3 vs 1497.8±819.2 pmol/L, p<0.001, 48.38±17.34 vs 73.96±26.29 pmol/L, p<0.001, and 9.51±8.33 vs 15.01±5.88 pmol/L, p<0.05, respectively, mean±SD). However, there were little differences in the ascorbic acid and uric acid concentrations in the induced sputum between the COPD patients and the controls. The induced sputum to serum ratio of ascorbic acid was significantly higher in COPD patients compared with healthy control (0.375 vs 0.085, p<0.05). In the normal controls, the serum ascorbic acid concentration was lower in smokers than in nonsmokers (1073±536 vs 1757±845 pmol/L, p<0.05), but the level was still higher than that of the COPD patients (p<0.05). The serum retinol levels were correlated with FEV1 in COPD patients (r=0.58, p<0.05). The products of lipid peroxidation were increased in normal smokers and COPD compared with normal nonsmokers (115.56±19.93 and 120.02±24.56 vs 91.87±20.71 µmol/µmol Pi of liposome, p<0.05). CONCLUSION: Cigarette smoking may induce the depletion of serum antioxidants and this depletion of antioxidants is suggested to play a role in the pathogenesis of COPD.
Antioxidants*
;
Ascorbic Acid
;
Chromatography, Liquid
;
Humans
;
Lipid Peroxidation
;
Liposomes
;
Oxidants
;
Pulmonary Disease, Chronic Obstructive*
;
Smoking
;
Sputum*
;
Uric Acid
;
Vitamin A
6.Emergency Trephination Site of Acute Subdural Hematoma.
Soo Hyeon MOON ; Geun Hoe KIM ; Taek Hyun KWON ; Youn Kwan PARK ; Hung Seob CHUNG ; Jung Keun SUH
Journal of Korean Neurosurgical Society 2000;29(5):659-663
No abstract available.
Emergencies*
;
Hematoma, Subdural, Acute*
;
Trephining*
8.Hemangioblastoma of the Conus Medullaris : Case Report.
Soo Hyeon MOON ; Se Hoon KIM ; Taek Hyon KWON ; Youn Kwan PARK ; Heung Seob CHUNG ; Jung Keun SUH
Journal of Korean Neurosurgical Society 2000;29(6):836-840
No abstract available.
Conus Snail*
;
Hemangioblastoma*
9.Hemangioblastoma of the Conus Medullaris : Case Report.
Soo Hyeon MOON ; Se Hoon KIM ; Taek Hyon KWON ; Youn Kwan PARK ; Heung Seob CHUNG ; Jung Keun SUH
Journal of Korean Neurosurgical Society 2000;29(6):836-840
No abstract available.
Conus Snail*
;
Hemangioblastoma*
10.Extramedullary Plsasmacytoma Developed in the Thoracic Epidural Space: Case Report.
Soo Hyeon MOON ; Jung Yul PARK ; Yoon Kwan PARK ; Hung Seob CHUNG ; Jung Keun SUH ; Hoon Gap LEE
Journal of Korean Neurosurgical Society 1994;23(10):1195-1201
Spinal cord compression associated with plasma cell neoplasm is observed always in the patients suffering from the multiple myeloma or solitary plasmacytoma that occur in the marrow of the spine. Authors report a rare case of extramedullary plasmacytoma forming a mass in the epidural space of the thoracic spine. In 70 year old woman with paraplegia, MRI of the thoracic spine indicated a presence of epidural mass at the 2nd to 8th thoracic vertebrae. There was no abnormal bony changes in the spine on plain X-ray and MRI. Total removal of the epidural mass was performed by posterior approach. Histopathologic examination including immunohistochemical stain showed the plasma cell neoplasm producing IgM and kappa light chain. Cancer workup after operation including bone marrow study and whole body simple radiologic studies supported the diagnosis of extramedullary plasmacytoma.
Aged
;
Bone Marrow
;
Diagnosis
;
Epidural Space*
;
Female
;
Humans
;
Immunoglobulin M
;
Magnetic Resonance Imaging
;
Multiple Myeloma
;
Neoplasms, Plasma Cell
;
Paraplegia
;
Plasmacytoma
;
Spinal Cord Compression
;
Spine
;
Thoracic Vertebrae