1.Comparative study of survival rate of gastric cancer patients according to TNM classification.
Chang Hoon LEE ; Kyung Hoon CHOI ; Jae Kwan SEO
Journal of the Korean Cancer Association 1993;25(2):170-175
No abstract available.
Classification*
;
Humans
;
Stomach Neoplasms*
;
Survival Rate*
2.Primary gallbladder cancer: review of 130 cases.
Chung Han LEE ; Kyoung Hyung CHOI ; Sung Do LEE ; Jae Kwan SEO ; Young Hoon PARK
Journal of the Korean Surgical Society 1992;42(4):493-506
No abstract available.
Gallbladder Neoplasms*
;
Gallbladder*
3.A clinical study of total gastrectomy for gastric cancer.
Sang Ill CHOI ; Chung Han LEE ; Kyung Hyun CHOI ; Sung Do LEE ; Jae Kwan SEO ; Young Hoon PARK
Journal of the Korean Surgical Society 1993;44(1):92-101
No abstract available.
Gastrectomy*
;
Stomach Neoplasms*
4.Peripheral Vascular Disease in Patients with Significant Coronary Artery Disease.
Dong Hun CHOI ; Jong Won HA ; Won Heum SHIM ; Moon Hyung LEE ; June KWAN ; Si Hoon PARK ; Yang Soo JANG
Korean Circulation Journal 1995;25(2):477-482
BACKGROUND: Although it is known that patients wth peripheral vascular disease are at high risk for coronary arterial disease, however, it has not been determined that patients with coronary artery disease(CAD) correlates with peripheral vascular disease(PVD). This study was designed to determine the prevalence and clinical characteristics of peripheral vascular disease(PVD) in patients with coronary artery disease(CAD). METHODS: A total of one hundred seventy-eight patients with CAD confirmed by coronary angiogram(145 male, age 58.5+/-10.1) were included in this study from February 1992 to May 1994. Coronary and peripheral angiograms were performed in all patients and the patients were divided into two groups; patients with PVD dand patients without PVD. Clinical characteristics were compared between two groups. RESULTS: Peripheral vascular disease was present in 49 patients(27.5%) among 178 CAD patients. The mean age of patients with PVD was significantly older than that of patients without PVD. The hypertension was statistically significant difference between two groups(P<0.05). There were no major differences in the number of risk factors or number of stenotic coronary arteries in patients with and without PVD. CONCLUSION: The prevalence of PVD in patients with CAD was high and it is reasonable to state that most common risk factors for coronary and peripheral atherosclerosis were age, hypertension and obesity.
Atherosclerosis
;
Coronary Artery Disease*
;
Coronary Vessels*
;
Humans
;
Hypertension
;
Male
;
Obesity
;
Peripheral Vascular Diseases*
;
Prevalence
;
Risk Factors
5.Clinical study of pancreatic cancer.
Hee Duck KIM ; Byung Ki LEE ; Kyung Hyun CHOI ; Sung Do LEE ; Jae Kwan SEO ; Young Hoon PARK
Journal of the Korean Surgical Society 1992;42(2):179-189
No abstract available.
Pancreatic Neoplasms*
6.The prognosis and long-term follow-up of multiple organ resection for stomach cancer.
Kwang Hee KIM ; Chung Han LEE ; Kyung Hyun CHOI ; Sung Do LEE ; Jue Kwan SEO ; Young Hoon PARK
Journal of the Korean Cancer Association 1992;24(6):871-879
No abstract available.
Follow-Up Studies*
;
Prognosis*
;
Stomach Neoplasms*
;
Stomach*
7.A Case of Peritoneal Tuberculosis with Elevated Serum CA 125 Level.
Hye Kyung KWON ; Tae Lim JOO ; Soon Mi CHOI ; Kook LEE ; Kwan Sik LEE ; Nam Hoon CHO
Korean Journal of Obstetrics and Gynecology 1997;40(8):1783-1787
Peritoneal tuberculosis is a disease rarely seen nowadays. Its symptoms are easy fatigue, abdominal distension, intermittent abdominal pain and ascites. Its onset is insidious, which si-mulates symptoms of peritonitis or carcinomatosis. Peritoneal tuberculosis should be considered in the differential diagnosis when a Patient's symptoms and signs are ascites, ovarian tumor, vague abdominal pain and abdominal distension with high serum level of CA 125, an antigenic determinant of epithelial ovarian cancers. We have recently experienced a case of peritoneal tuberculosis with markedly elevated serum level of CA 125 in 54 year-old woman and report our case with a brief review of the literature.
Abdominal Pain
;
Ascites
;
Carcinoma
;
Diagnosis, Differential
;
Fatigue
;
Female
;
Humans
;
Middle Aged
;
Ovarian Neoplasms
;
Peritonitis
;
Peritonitis, Tuberculous*
8.Review of Pragmatic Clinical Trials on Acupuncture
Sang-hoon Lee ; Byung-kwan Seo ; Jung-chul Seo ; Seung-deok Lee ; Sun-mi Choi ; Yong-suk Kim
Journal of the Japan Society of Acupuncture and Moxibustion 2005;55(5):716-722
[Background] Over the last thirty years, majority of researches on clinical effectiveness of acupuncture have been explanatory (or experimental) randomized controlled trial. The benefits of acupuncture in clinical trials are stillcontroversial and most studies concluded that further control studies were required. Standardized combinations of acupuncture points for all the experimental subjects in various past studies have been criticized because such treatments do not reflect current routine clinical treatment.
[Objective] This paper aims to review pragmatic clinical trials on the effect of acupuncture treatment and to develop the ideal clinical research methodology of acupuncture study.
[Method] Clinical studies of acupuncture relevant with pragmatic or individualized trials were searched mainly in Pubmed and Science direct databases. All articles were fully reviewed by researchers, and data were evaluated by usage of a standardized form.
[Results & Suggestion] Pragmatic acupuncture researches were tried for various symptoms (eg. low back pain, hypertension, depression during pregnancy, sleep quality in HIV disease, chronic poststroke leg spasticity, headache, etc). Individualized acupuncture treatments based on oriental disease pattern diagnosis reflexes practical treatments which is more effective than unified and fixed acupuncture treatments without any theoretical basis of oriental medical philosophy.
[Conclusion] To overcome the controversies and limitations of past explanatory acupuncture trials, more individualized and tailored acupuncture trials with the theoretical basis of oriental medical diagnosis is highly recommended. Also clear definition and categorization of pattern identification should be established for further active clinical researches and applications of acupuncture.
9.Clinical Analysis of Porencephaly.
Jeong Hoon LEE ; Won Han SHIN ; Soon Kwan CHOI ; Bark Jang BYUN ; In Soo LEE
Journal of Korean Neurosurgical Society 1989;18(5):784-789
We have reviewed series of seven cases of porencephaly. The etiologic factors, the symptomatology, the location of the various lesions and the treatment have been briefly discussed. According to their etiology, we believed that case 1 was caused by circulatory disturbance due to arteriovenous malformation, case 2 by neonatal intracranial hemorrhage(subependvmal hemorrhage), case 3 by non-specific inflammation, and case 4, 5, 6 & 7 by cerebral contusion and skull defect. Three(case 1, 2 & 3) of our seven patients had convulsions, hemianopsia and hemiparesis. but the others(case 4, 5, 6 & 7) had non-specific symptoms. In seven cases, four of the cysts occurred in the left hemisphere(case 1, 2, 3 & 6) in three in the right(case 4, 5 & 7). Three of our cases had cysts in the frontal lobe(case 1, 4 & 6) two in the parietal lobe(case 3 & 7), one in parieto-occipital lobe(case 2) and one in frontoparietal lobe(case 5). CT scan had been very useful in evaluating of these cysts. In our seven patients five cases were diangosed by CT scan and in two cases the diagnosis was verified at operation. In all cases the operation was done by removal of portion of arachnoid and cortex overlying the porencephalic cysts and adequate drainage of porus into the lateral ventricle and subarachnoid space. Postoperatively three cases who had seizure have been completely relieved from convulsions.
Arachnoid
;
Arteriovenous Malformations
;
Contusions
;
Diagnosis
;
Drainage
;
Hemianopsia
;
Humans
;
Inflammation
;
Lateral Ventricles
;
Paresis
;
Rabeprazole
;
Seizures
;
Skull
;
Subarachnoid Space
;
Tomography, X-Ray Computed
10.The Effects of Nicotine and NNK on gingival fibroblast.
Chi Hoon HWANG ; Mi Young PARK ; Kwang Kyun PARK ; Seong Ho CHOI ; Kyoo Sung CHO ; Chong Kwan KIM ; Jung Kiu CHAI
The Journal of the Korean Academy of Periodontology 1998;28(4):703-719
In order to observe the effects of Nicotine and NNK on cultured human gingival fibroblast, several factors were examined including mutagenicity, the number of cells attached culture plate surface through MTT test, the abundance of collagen & collagenase in mRNA level and collagenolytic activity in extracellular matrix. The results were as follows; 1. Regardless of the co-existence of S9, Nicotine did not show the mutagenicity by itself and NNK by itself showd the same result; However, dose related mutagenicity was shown in NNK with S9. 2. The number of fibroblasts attached cultured plate surface was measured by MTT procedure. The number of cells in Non-smokers increased at all time periods as compared to those of smoker. 3. Non-smoker's fibroblast treated by NNK or Nicotine was dose-dependently decreased in the number of cells when compared to untreated control. In higher dose, Nicotine showed the cellular toxicity , but NNK did not. 4. No change in the abundance of mRNA for proalpha1 and proalpha2 was shown in Nicotine treated group but in gingival fibroblasts following treatment with NNK, the abundance of mRNA for proalpha1, but not proalpha2 collagen was decreased. 5. The abundance of mRNA for collagenase was decreased when NNK was treated but no change occurred in Nicotine treated group. 6. The effect of NNK and Nicotine in collagenolytic activity showed that ,collagenase activity exclusively react to type I collagen, was increased in both group, but gelatinase exclusively react to type IV collagen was not influenced at all. Collagenase activity of smoker's fibroblast was also increased as much as Nicotine and NNK group. The findings suggest that both of Nicotine and NNK lead gingival fibroblast to decrease in the abundance of collagen. And it seems to be that Nicotine and NNK have independent pathway toward the gingival fibroblast.
Humans