No abstract available.
HL-60 Cells* ; Humans ; Mass Screening* ; Protein Kinases*

Dried specimens of the genus Inocybe collected from mountain areas throughout the Korean country from 1982 to 1998 and preserved in NIAST were investigated. Out of them, Inocybe hystrix were confirmed as an unrecorded species in Korea. In 1991 Lee et al., previously recorded Inocybe kasukayamensis only with its scientific name and korean common name. In this study we report it with full descriptions of morphological characteristics and diagnosis of micro-structures of this species.
Diagnosis ; Korea* ; Porcupines

No abstract available.
Clone Cells* ; Cloning, Organism* ; Nucleopolyhedrovirus*

A fabrication method of inner and outer crown using CAD/CAM is presented. The information of abutment teeth is transferred to a computer through a 3-dimensional scanner. A Konus inner and outer crown is designed on a computer and a real crown is machined based on this design using CAM. This method can save laboratory time and reduce inaccuracies compare to conventional casting procedure. A stone model with six prepared abutment teeth from a patient was used in this study. Three dimensional information from the model was transferred to a computer using a contact type 3dimensional scanner with a 25micrometer accuracy. All margins were identified on a computer image where there is a change in surface taper of a model. To provide a cement space, the image of a inner surface of a Konus inner crown was duplicated 25micrometer apart from the surface of a prepared abutment teeth image. The cement space was 20micrometer at the cervical margin. All Konus crowns were machined with a 10micrometer accuracy. It was concluded that this method can reduce working-time for the laboratory process and increase accuracy. A further research is required to make a simplified process for a more complex prosthesis.
Computer Graphics* ; Crowns* ; Humans ; Prostheses and Implants ; Tooth

Childhood obesity has rapidly increased worldwide and is one of the most serious health problems in this age group. In order to prevent and manage childhood obesity, we developed a nutrition education website. The website consisted of three parts. The first part was made for self-assessment with regard to obesity index, dietary habits, food frequency, dietary attitude, nutrition knowledge, nutrient intake, energy expenditure, and the stage of behavioral change, and tailored messages and advice according to the assessment results. A total of 612 real-size food photos as well as a nutrient database of 3,346 foods and 541 dishes were created to help children estimate nutrient intakes accurately. In addition, an energy expenditure database of 156 activities for children was established to calculate calorie consumption. The second part was made for setting long-term and short-term goals and keeping track of the changes in energy intake and expenditure in one's own page. The third part was made for education. Various types of nutrition information were provided; texts, pictures, calculators and games. The readability and design of the website were evaluated by 46 obese children. Usefulness, design and readability of the website were found to be desirable for children. This website is expected to be used by an obese child alone or with parents or nutrition teachers in order to control body weight through healthy dietary habits and physical activities. In addition, a non-obese child can also use this website for maintaining healthy dietary habits and preventing obesity.
Body Weight ; Child ; Comprehension ; Energy Intake ; Energy Metabolism ; Food Habits ; Health Expenditures ; Humans ; Motor Activity ; Obesity ; Parents ; Self-Assessment ; Track and Field

Precise bracket positioning is essential in modern orthodontics. However, there can be alterations in the vertical position of a bracket due to several reasons. The purpose of this study was to evaluate the effect of variations in the vertical bracket position on the crown inclination in Korean patients with normal occlusion. From a larger group of what was considered to be normal occlusions obtained from the Department of Orthodontics, College of Dentistry, Seoul National University, each of the final 10 subjects (6 males and 4 females, with an average age of 22.3 years) was selected. The dental models of each of the subjects were scanned three-dimensionally by a laser scanner, and measurements drawn from these were made on the scanned dental casts of the subjects were input into the computer program. From this the occlusal plane and the bracket plane were determined. The tooth plane was then constructed to measure the crown inclination on the bracket plane of each tooth. From a practical standpoint, information was obtained on the extent to which the torque of a tooth would be changed as the bracket position was to be moved vertically (in +/-0.5 mm, +/-1.0 mm, +/-1.5 mm) from its ideal position. A one way analysis of the variance (ANOVA) was used to compare each group of the different vertical distances from the bracket plane on a specific tooth. Duncan's multiple comparison test was then performed. There were statistically significant differences in the crown inclination among the groups of different vertical distances for the upper central incisor, upper lateral incisor, upper canine, upper first and second molars, lower first and second premolars, and lower first and second molars (p<0.05). On the upper anterior teeth, upper molars, lower premolars and lower molars, the resultant torque values due to the vertical displacement of the bracket were different depending on the direction of the displacement, occlusal or gingival. This study implies that the torque of these teeth should be handled carefully during the orthodontic treatment. In circumstances in which the bracket must be positioned more gingivally or occlusally due to various reasons, it would be useful to provide the chart of torque alteration of each tooth referred to in this study with its specified bracket prescription.
Bicuspid ; Crowns* ; Dental Models ; Dental Occlusion ; Dentistry ; Female ; Humans ; Incisor ; Male ; Molar ; Orthodontics ; Prescriptions ; Seoul ; Tooth ; Torque

SAPHO (synovitis, acne, pustulosis, hyperostosis, osteitis) syndrome designates a group of articular and osseous manifestations frequently combined with skin disorders. Its fundamental component is inflammatory, pseudoinfectious, and sterile osteitis. The anterior chest wall is the most frequent localization and all the components of this structure may be involved. Palmoplantar pustulosis, psoriasis, acne conglobata, acne ulcerans, acne fulminans, pyoderma gangrenosum can be associated with the characteristic bone lesions. We report two cases of SAPHO syndrome : A 40-year-old female presented with both buttock pain with hyperostosis, costochondritis, synovitis and pustulosis palmaris and a 23-year-old male presented with migrating polyarthritis with costochondritis, synovitis, acne, pustulosis.
Acne Vulgaris ; Acquired Hyperostosis Syndrome* ; Adult ; Arthritis ; Buttocks ; Female ; Humans ; Hyperostosis ; Male ; Osteitis ; Psoriasis ; Pyoderma Gangrenosum ; Skin ; Synovitis ; Thoracic Wall ; Young Adult

The statistical observation of the time of passage of the first stool and first void was performed on 800 cases of newborns, were carried at the newborn nursery and premature baby room, National Seoul Hospital, during the past two years from Jan, 1977 to Dec, 1978. The population study was performed on sex, gestational age, Apgar score, mode of delivery, and maternal disease or premedication during the pregnancy, congenital anomalies of the newborn infants. The results were as following. 1) The cases of passage of the first stool within 1 hour and 24 hours after birth were 15%, 96.9% of total boy and 12.4%, 97.1% of total girl in each cases. There were no remarkable differences in the time of first stool between the boys and girls. The cases of the first stool passage who was delayed until 48 hours of age were more frequent in boys(0.7%) than girls. The cases of the first voiding in the delivery room or within 1 hour after birth showed 8.2% of boys and 6.7% of girls and the cases after 24 hours of age showed 6.5%, 5.2%, relatively. This revealed that boys were more earlier than girls in their first voiding. 2) According to gestational age, a total of 98.5% and 94.5% of the fullterm infants had their first stool passing and voiding within 24 hours after birth. But 10.8% of preterm infants had their first stool just after birth and 2.4% of preterm infants had their first meconium after 48 hours of age. So this group tended to pass their first stool later than other groups of infants. And also 23.2% of postterm infants had their first stool just after birth and this group tended to pass their first meconium earlier than other group of infants. A total of 97.6% of preterm infants voided in the delivery room and 88.4% of postterm infants had urinated within 24 hours after birth. This showed that preterm infants tended to void early and the postterm infants tended to void later than other groups of infants. 3) According to apgar score, 41.7% of newborn infants with low Apgar score(score 0~4) had their first stool passage in the delivery room and 66.7% of low Apgar score group infants voided within 24 hours after birth and this group tended to pass their stool earlier and void later than high Apgar score group infants. 4) The delivery method did not influence to the general population in the time of first urination and stool passage. 5) The infants of preeclampsia or diabetic mother tended to void early and the infants born to mother who received diuretics during the pregnancy voided early also. The newborn infants who had combined with congenital anomalies of gastrointestinal tract or genitourinary tract were delayed the time of passage of the first stool or first urine.
Apgar Score ; Delivery Rooms ; Diuretics ; Female ; Gastrointestinal Tract ; Gestational Age ; Humans ; Infant ; Infant, Newborn* ; Infant, Premature ; Male ; Meconium ; Mothers ; Nurseries ; Parturition ; Pre-Eclampsia ; Pregnancy ; Premedication ; Seoul ; Urination

This study reports the protective of systemic nicardipine and intracisternal nicardipine administration in the three-hemorrhage canine model of chronic cerebral vasospasm. Twenty-one dogs were assigned to one of three groups : control, intravenous nicardipine, and intracisternal nicardipine. All animals received a total of 12ml of fresh unheparinized autologous blood via three cisternal injection. Selective vertebral angiograms were obtained before intravenous nicardipine for 7 days continuously, the other seven were treated by intracisternal nicardipine for 7 days, and the remaining were not treated. Animals were sacrificed at day 9. Comparisons were based on the percentage of reduction in basilar artery diameter(% RBAD). The ultrastructural changes were studied by transmission electron microscopy(TEM). There was a mean reduction(+/- standard deviation) of 54+/-6% in control dogs, 35+/-4% in dogs with intravenous nicardipine, 32+/-6% in dogs with intracisternal dicardipine(difference significant, t-test, P<0.05). The preventive effects of intracisternal nicardipine was superior to those of intravenous nicardipine. There was a strong trend toward reduction of medial necrosis in the basilar artery in dogs with intravenous and intracisternal group compared to control dogs. All basilar arteries showed structural changes with celectron microscopic examination ; these included medial necrosis, lysosome, initial changes, endothelial cell vacuoles, and adventitial erythrocytes, leukocytes. Intimal proliferation was unusual in all three groups, but reduction of intimal proliferation was found in dogs with treatment, and it was believed that vasospasm in this stage is due to long-standing smooth muscle contraction and not to arterial wall thickening. There was significant reduction of blood clot in intracisternal nicardipine group, which may be due to inhibitory action on platelet aggregation of nicardipine. These investigations support the hypothesis that the presence of clotted blood around the intracranial arteries is the cause of vasospasm.
Animals ; Arteries ; Basilar Artery ; Dogs ; Endothelial Cells ; Erythrocytes ; Leukocytes ; Lysosomes ; Muscle, Smooth ; Necrosis ; Nicardipine* ; Platelet Aggregation ; Vacuoles ; Vasospasm, Intracranial*

Neuroleptic malignant syndrome (NMS) is a rare, but a potentially life threatening condition associated with the use of antipsychotics. The most frequent signs and symptoms of NMS include fever, muscle rigidity, autonomic dysfunction such as tachycardia, tachypnea, and labile blood pressure. Acute complications of NMS include disseminated intravascular coagulation, sepsis, seizure, myocardial infarction, acute renal failure due to rhabdomyolysis and death. We report a rare case of acute renal failure due to rhabdomyolysis associated with neuroleptic malignant syndrome.
Acute Kidney Injury ; Antipsychotic Agents ; Blood Pressure ; Disseminated Intravascular Coagulation ; Fever ; Muscle Rigidity ; Myocardial Infarction ; Neuroleptic Malignant Syndrome ; Rhabdomyolysis ; Seizures ; Sepsis ; Tachycardia ; Tachypnea