1.Breastfeeding counsel against cancers
Asian Pacific Journal of Tropical Biomedicine 2016;6(5):422-428
The anticancer potential by breastfeeding is not fully tapped in the light of the present knowledge of the subject. Literature indicates that breastmilk has anticancer action but may underestimate its full capacity. The protective spectrum within breastmilk hints on the need for a more comprehensive understanding of it as an anticancer tool. Exclusive breastfeeding could confer protection from carcinogenesis with a greater impact than realised. A literature review was conducted using four electronic databases. Selected areas were extracted after thorough perusal of the articles. The uninitiated would take exclusive breastfeeding seriously if actively counselled as an anticancer tool. Advice on details of the breastfeeding process and holistic information on breastfeeding may endow a greater impact among the skeptics. Counselling the breastfeeding mother on information sometimes not imparted, such as on maternal nutrition, details of the process of breast-feeding, benefits of direct breastfeeding versus milk expression and her psychosocial well being may make a difference in optimising anticancer action that exists in breastmilk. Additionally, its anticancer potential provides a platform to universally improve physical and psychosocial well being of women who breastfeed. Statistics of protection by breastfeeding in some maternal and childhood cancers are evident. “Bio-geno-immuno-nutrition” of breastmilk may shield the mother and infant from carcinogenesis in more ways than appreciated. The molecular basis of mother-to-infant signals and their “en-ergies” need to be researched. Breastfeeding as a modifiable behaviour provides cost effective nutrition with potential for both cancer immunoprophylaxis and immunotherapy.
2.HIV transmission through breastmilk: the science behind the understanding of current trends and future research
The Medical Journal of Malaysia 2012;67(6):644-651
Breastmilk protects the infant from many diseases and
many short- term and long- term benefits accrue. At the
same time it is also known that breastfeeding acts as a
vehicle for some infective agents. It is now accepted that
breastmilk transmission of Human Immunodeficiency Virus-
1 (HIV-1) is an important mode of paediatric infection .
Despite this fact, many researchers have observed that
corresponding to the volume of milk consumed by the
infant, maternal transmission via breastmilk is still
comparatively low. Some have noted the long latency period
of breastmilk HIV transmission with evidence of numerous
anti-HIV factors in breastmilk.
Although there are accepted standard guidelines on infant
feeding in mothers who are HIV positive in many countries,
it maybe equally important to realize gaps in our knowledge
of mother- to -child HIV transmission. From an
evolutionary perspective, the role of the mammary epithelial cell (MEC) and of breastmilk , in contributing to and possibly in influencing HIV-1 transmission is intriguing. The presence of HIV-1 or of other viruses in maternal milk seem to be a requisite to spur immunological defenses to optimize necessary protection to the infant. This article reviews some aspects of the science of HIV transmission through breastmilk and reflects the concept -based understanding of current policies on HIV and breastfeeding. At the same time, it highlights uncertainties in this field and the urgency for future research in this direction. Accepting current notions of breastmilk HIV transmission, greater deliberation by research may throw more light on why breastfeeding with its abundant advantages is fraught with the hazards of transmission of a deadly disease.
3. Breastfeeding and risk of parasitic infection-A review
Asian Pacific Journal of Tropical Biomedicine 2014;4(11):847-858
Breastfeeding, as exclusive nutrition in the first six months of life, is a necessary nutritional requisite in infants. Except for very few maternal diseases that contraindicate breastfeeding, some of which still controversial, breastfeeding mothers must continue exclusive and sustained lactation to provide maximum overall benefits through breastfeeding. Parasitic infections is a global disease and children remain a significant proportion of the affected population. The complex and mandatory life cycles of some parasites, particularly the helminths may partly explain their geographical distribution. The world-wide prevalence of parasitic infections as well as the largely asymptomatic nature of most infections, make many of these infections to likely remain under-recognized. Breast milk, the prime infant nutrition must be recognized to be more than a rare vehicle of parasite transmission, but also a general and focused immune defensive tool against some important parasites. The possibility and influence of small quantities of parasite antigens in breast milk have not been adequately explored. It is believed that useful immunological responses both direct and indirect in breast milk that occur due to the presence of parasite antigens, must be further studied in the light of both immediate and long term benefits. Within this context, and prompted by a spectrum of existing uncertainties, researched and hypothetical roles of parasites and associated immunological responses in the lactating mammary gland are proposed and reviewed.
4. Breastfeeding counsel against cancers
Asian Pacific Journal of Tropical Biomedicine 2016;6(5):422-428
The anticancer potential by breastfeeding is not fully tapped in the light of the present knowledge of the subject. Literature indicates that breastmilk has anticancer action but may underestimate its full capacity. The protective spectrum within breastmilk hints on the need for a more comprehensive understanding of it as an anticancer tool. Exclusive breastfeeding could confer protection from carcinogenesis with a greater impact than realised. A literature review was conducted using four electronic databases. Selected areas were extracted after thorough perusal of the articles. The uninitiated would take exclusive breastfeeding seriously if actively counselled as an anticancer tool. Advice on details of the breastfeeding process and holistic information on breastfeeding may endow a greater impact among the skeptics. Counselling the breastfeeding mother on information sometimes not imparted, such as on maternal nutrition, details of the process of breastfeeding, benefits of direct breastfeeding versus milk expression and her psychosocial well being may make a difference in optimising anticancer action that exists in breastmilk. Additionally, its anticancer potential provides a platform to universally improve physical and psychosocial well being of women who breastfeed. Statistics of protection by breastfeeding in some maternal and childhood cancers are evident. "Bio-geno-immuno-nutrition" of breastmilk may shield the mother and infant from carcinogenesis in more ways than appreciated. The molecular basis of mother-to-infant signals and their "energies" need to be researched. Breastfeeding as a modifiable behaviour provides cost effective nutrition with potential for both cancer immunoprophylaxis and immunotherapy.
5.Breastfeeding during breast milk jaundice - a pathophysiological perspective
The Medical Journal of Malaysia 2019;74(6):527-533
Introduction: Exclusive breastfeeding for the initial six
months of life is crucial and it is recommended . Breast milk
jaundice is an innocuous condition that occurs in some
healthy, breastfed infants. However, the potential dangers of
jaundice in the neonate such as bilirubin induced neuronal
pathology, mandates a better understanding of the
pathophysiology of breast milk jaundice and the impact of
breastfeeding during jaundice. In this context , advice on
continued breastfeeding must consider both the benefits of
breastfeeding and the possible disadvantages of the
jaundice.
Methods. Reviewing literature and integrating relevant
information facilitated the appraisal of this important topic.
This article reviewed neonatal jaundice, the entry of bilirubin
into the immature brain and how breastfeeding may impact
jaundice in the neonate.
Results. While some substances in breast milk may be
responsible for jaundice on the one hand, there is an
irrefutable spectrum of advantages conferred by continued
breastfeeding, on the other. As the breastfed infant benefits
from fewer infections, enhanced organ and physiological
barrier maturity, as well as the prospect of genetic
modification of certain diseases, these useful actions could
also reduce risks of early jaundice and its complications.
Discussion. An exciting field for further research, holistic
integration of knowledge clarifies both the overall
advantages of breastfeeding and wisdom of its continued
counsel. In fact, breast milk jaundice may reflect a holistic
expression of tissue protection and enhanced neonatal
survival.