The aim of this study was to investigate the source and the size of a tularemia outbreak in a village located in a non-endemic area. Five patients from the same village were admitted to hospital with the same complaints all within one week of September 2001. Tularemia was suspected and a diagnosis was made after physical and anamnesis examinations. The village was visited the same week that the patients were admitted to the hospital, in the January and April 2002. The villagers were examined and screened serologically by microagglutination method and the water sources were investigated bacteriologically. A total of 14 people were found to be infected from the outbreak and the oropharyngeal form was the only clinical presentation. Antibody titers ranged between 1 : 80 and 1 : 640. The patients responded well to the aminoglycoside plus tetracycline therapy. Examination of the pipewater and three springs revealed that all the water sources were contaminated by coliforms, however, Francisella tularensis could not be isolated in glucose-cystine medium. Antibody levels stayed stable or decreased seven months after. Tularemia had not been reported in this area before, so the first patients were misdiagnosed. In conclusion tularemia should be considered in differential diagnosis of patients with fever, sore throat and cervical lymphadenopaties.
Adolescent ; Adult ; Aged ; Animals ; Child ; *Disease Outbreaks ; Female ; Human ; Male ; Middle Aged ; Rats ; Seasons ; Seroepidemiologic Studies ; Tularemia/*epidemiology/*transmission ; Turkey/epidemiology ; Water Supply

In this report, an ameloblastoma case, which has been occurred on the left maxilla of a 10 year-old, male, German shepherd, was described on the clinical and morphological features. The mass with the dimensions of 5x2.5 cm was removed totally by maxillectomy and examined by radiography, magnetic resonance (MR) and biopsy. The tumor was histopathologically classified ameloblastoma of follicular type and in some fields showed acanthotic form. The invasiveness of the tumor was also observed to be high. This report is the first case of maxillary ameloblastoma in dogs in Turkey.
Ameloblastoma/*pathology/*veterinary ; Animals ; Dog Diseases/pathology ; Dogs ; Male ; Maxilla/pathology ; Maxillary Neoplasms/*pathology/*veterinary ; Neoplasm Invasiveness/pathology

AIMTo investigate the feasibility of the autologous fascia graft in urethra defect reconstruction.

METHODSIn 24 adult male rabbits, a standardized defect (17 mm) was created within the midportion of each urethra. Two-cm long fascial tube grafts were interposed between the cut ends of the urethra. Twenty-four rabbits were divided into 12 groups. At 0, 3, 10, 15, 21, 30, 45, 60, 90, 120, 150, and 180 days postoperatively, one group was killed. In the first four groups, rabbits were killed and specimens were obtained for histological examination. After 21 postoperative days, in the subsequent eight groups, retrograde urethrograms were carried out to evaluate urethral patency and caliber, then rabbits were killed and specimens were obtained.

RESULTSIn the histological study, advancement of the urethral transitional epithelium along scaffold provided by the fascial graft was determined. At the 30th day, the new urethra was completely covered with the transitional epithelium. Fistula formation was observed in two of 24 rabbits. In urethrograms, narrowing was determined in three of 16 rabbits.

CONCLUSIONFor segmental urethral reconstruction, fascial graft is a good urethral substitute because of its rapid epithelization capacity, low contraction degree and thinness. We therefore propose the use of fascial grafts for reconstruction of male-urethra defects in humans.

Animals ; Disease Models, Animal ; Fascia ; diagnostic imaging ; pathology ; transplantation ; Male ; Pilot Projects ; Rabbits ; Radiography ; Urethra ; diagnostic imaging ; pathology ; surgery ; Urethral Diseases ; pathology ; surgery ; Urologic Surgical Procedures, Male ; methods

This paper reports a presumptive severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) infection in a cat. A cat with respiratory disease living with three individuals with coronavirus disease 2019 showed bilateral ground-glass opacities in the lung on X-ray and computed tomography. The clinical swabs were negative for SARS-CoV-2 RNA, but the serum was positive for SARS-CoV-2 antibodies. Interstitial pneumonia and prominent type 2 pneumocyte hyperplasia were noted on histopathology. Respiratory tissues were negative for SARS-CoV-2 RNA or antigen, but the cat was positive for feline parvovirus DNA. In conclusion, the respiratory disease and associated pathology in this cat could have been due to exposure to SARS-CoV-2.