1.Clinical analysis of 11 patients with reversible posterior leukoencephalopathy syndrome
Kun LIU ; Wenwen SU ; Dunbo YU
Chinese Journal of Primary Medicine and Pharmacy 2012;19(20):3064-3065
ObjectiveTo explore the clinical characteristics of reversible posterior leukoencephalopathy syndrome ( RPLS ),in order to deepen the awareness of the disease.MethodsThe clinical data of 11 patients with RPLS in our hospital were retrospectively analyzed.ResultsIn the 11 cases with RPLS,there were two cases of pregnancy induced hypertension,preeclampsia(38 weeks pregnant),four eases of chronic renal insufficiency,four cases of malignant hypertension,and one case of lung cancer after chemotherapy.The main clinical presentations were headache,abnormality of visual perception,mental and behavioral abnormalities,ataxia,epileptic seizure and so on.The neuroimaging performances were extensive white matter abnormalities of the rear of the bilateral cerebral hemispheres,such as the parietal-occipital temporal lobe lesions,also involving the brain stem,cerebellum,thalamus and other parts.ConclusionThe clinical characteristics and neuroimaging performances of RPLS has certain characteristics,the majority of lesions were reversible,if the early diagnosis and treatment,the prognosis is usually good.
3.A STUDY ON THE CONTENT OF FATTY ACII S IN EIGHT KINDS OF COMMON SHELLFISH
Taiwu LI ; Xiurong SU ; Kun LI
Chinese Journal of Marine Drugs 1994;0(02):-
In this paper, the composition and contents of fatty acids in eight kinds of common shellfish in the Dalian Coast were studied. They were Neverita didyma and Neptunea cumingi of Gastropoda. Scapharca subcrenata, Mytilus edulis, chlamys farreri, Ruditapes philippinarum, Mactra veneriformis, Sinonovacula constrica of Lamellibranchia. Comparison with Stichopus japonicus, Penaeus orientalis, Upogebia and Portunus trituberculatus was also done. The results showed nutritive values of eight kinds of common shellfish.
4.Effects of gastrin 17 and pepsinogen on anastomotic ulcer after gastric bypass surgery for resection of pyloric antrum
Jie LI ; Yan SUN ; Wei SU ; Kun CHEN ; Chengzhe SUN
Tianjin Medical Journal 2017;45(9):965-968
Objective To study the changes of gastrin 17 (G17) and pepsinogen (PG) after gastric bypass surgery in gastric antrum resection, and the influences of different surgical methods on postoperative peptic ulcer. Methods Clinical data of 63 patients with gastric bypass surgery in our hospital from October 2013 to October 2015 were divided into resection of pyloric antrum group (n=33) and preserved pyloric antrum group (n=30). The values of G17, PGⅠ, PGⅡand PGⅠ/PGⅡwere detected by enzyme linked immunosorbent assay at 1 month, 6 months and 12 months after operation. The correlation between the different surgical methods and the incidence of peptic ulcer was analyzed between two groups. Results The G17 levels were significantly decreased in resection of pyloric antrum group 6 and 12 months after operation than those in preserved pyloric antrum group (P<0.05). Compared with preserved pyloric antrum group,PGⅠ and PGⅡ levels was significantly decreased 12 months after operation (P<0.05). There was no significant difference in the ratio PGⅠ/PGⅡat 1 month, 6 months and 12 months after operation between two groups (P>0.05). There was no significant difference in postoperative peptic ulcer between two groups (P>0.05). Conclusion Gastric bypass after resection of the pyloric antrum can reduce the postoperative secretion of G17, PGⅠ and PGⅡ, but which can not reduce the incidence of postoperative anastomotic ulcer.
5.Accuracy of ultrasonographic measurement of transverse diameter of cricoid cartilage in selecting cuffed endotracheal tube size for pediatric patients
Xiangfei SU ; Shuling PENG ; Sujuan DU ; Kun ZHANG ; Yuxuan PENG
Chinese Journal of Anesthesiology 2017;37(7):784-787
Objective To evaluate the accuracy of ultrasonographic measurement of the transverse diameter of the cricoid cartilage in selecting the cuffed endotracheal tube (ETT) size for pediatric patients.Methods A total of 120 pediatric patients of both sexes,of American Society of Anesthesiologists physical status Ⅰ or Ⅱ,aged 1 month-6 yr,with body mass index of 10.9-31.2 kg/m2,undergoing endotracheal intubation and general anesthesia,were divided into group A and group B,with 60 pediatric patients in each group.The pediatric patients were intubated with a cuffed ETT in two groups.The ETT size was selected based on the transverse diameter of the cricoid cartilage measured by ultrasonography in group A.The ETT size was selected according to the age-based formula in group B.A tracheal leak was detected after intubation to determine whether or not the ETT size selected was appropriate.ETTs were replaced when the actually selected ones were not appropriate,and the number of replacement was recorded.The development of intubation-related complications was also recorded.Results The accurate rate of cuffed ETT size selected at the first time was 95% in group A,and it was significantly higher than that in group B (60%) (P< 0.05).There was no significant difference in the incidence of intubation-related complications between the two groups (P>0.05).Conclusion Uhrasonographic measurement of the transverse diameter of the cricoid cartilage produces higher accuracy in selecting the cuffed ETT size for pediatric patients and is worthy of clinical application.
6.Transmembrane Segment Analysis of Transient Receptor Potential Channel
Qiuxiang SU ; Liyan ZHANG ; Kun JI ; Gaigai ZHANG ; Lihua ZHANG
Journal of China Medical University 2016;45(7):610-615
Objective To investigate the membrane topology of transient receptor potential(TRP)channel. Methods Glycosylation method was used to investigate the membrane integrations of each hydrophobic segment of canonical TRP(TRPC5). Results In TRPC5 channel,S4?S8 segments were integrated into membrane with Ncyt/Cexo and Nexo/Ccyt orientations sequentially ,and C?terminus was intracellular. S1?S3 segments were integrated into membrane with two possible types. One was that S1 and S3 were integrated into membrane,whereas S2 was left out of the membrane on the cytosolic side;and the other was a mixed type that S1 and S3 were exposed to cytoplasm respectively. Both of them,the N?termi?nus was intracellular. Conclusion S4?S8 segments of TRPC5 are transmembrane segments. The integrations of S1?S3 segments into membrane need to be further investigated.
7.The role of microembolic signal monitoring in brainstem infarction and vertebrobasilar artery stenosis
Yanhong RONG ; Kun ZHAO ; Hongjun SU ; Jinlong QI
Tianjin Medical Journal 2016;44(3):363-366
Objective To investigate the relation between microembolic signals (MES) and vertebral basilar artery ste?nosis in patients with brainstem infarction. Methods A total of 156 patients with acute brainstem infarction, who were de?termined the cerebral infarction lesion and vertebral basilar artery stenosis by cranial magnetic resonance imaging and CT an?giography, and were monitored by transcranial Doppler via occipital window of basilar arterial MES monitoring in 7 days of the onset, were divided into microembolus signal negative group (n=136) and positive group (n=20). The clinical data were compared between two groups. The differences of different degrees of stenosis were analyzed in two groups. The differences of different locations of stenosis in patients with vertebral basilar artery stenosis were analyzed in two groups. Logistic regres?sion analysis was used to analyse the factors affecting MES. Results There were no significant differences in age, gender, history of hypertension and diabetes mellitus between the two groups (P<0.05). There were significant differences in the dif?ferent degrees of stenosis between two groups, no or mild stenosis was found in MES-negative group and severe stenosis in MES-positive group (P<0.05). There were 70 cases with no vertebral basilar artery stenosis, 86 cases with mild, moderate and severe stenosis, in which 14 cases were MES-positive and 72 cases were negative. There were significant differences in different locations of stenosis between the two groups. The proportion of multiple infarctions was significantly higher in MES-positive group than that of MES-negative group (P<0.05). The intracranial vertebral basilar artery stenosis and 75%of ver?tebral basilar artery stenosis were the independent risk factors of MES-positive. Conclusion Severe stenosis of the verte?bral basilar artery is more vulnerable to occur MES of posterior circulation, leading to cerebral infarction. Microemboli may be the cause of multiple infarctions in patients with vertebral basilar artery stenosis.
8.Avulsion Injury of the Flexor Digitorum Profundus Tendon: A Case Report
Jong Seok PARK ; Won Kee CHOI ; Chi Su SON ; Hee KWON ; Jun Min SONG ; Su Kun RAH
The Journal of the Korean Orthopaedic Association 1996;31(5):1105-1108
Avulsion injury of the flexor digitorum profundus tendon from distal phalanx is considered as a rare injury. Accrording to the classification by Leddy and Pacter, this case is Type III, which is a large bony fragment retained by the tendon. The distal pulley prevents retraction beyond the middle phalanx. We are reporting a case with brief review of literatures.
Classification
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Tendon Injuries
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Tendons
9.The STAT3 in Glucose Homeostasis.
Bon Jeong KU ; Su Hyeon PARK ; Koon Soon KIM ; Young Kun LIM ; Min Ho SHONG
Journal of Korean Society of Endocrinology 2004;19(3):274-280
No abstract avaiable.
Glucose*
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Homeostasis*
10.Effects of gender on incidence of intraventricular hemorrhage in very low and extremely low birth weight infants
Si CHEN ; Su LIN ; Hao ZHANG ; Qingqing JIE ; Kun SHANG ; Li WANG ; Zhenlang LIN
Chinese Journal of Perinatal Medicine 2014;17(5):317-322
Objective To examine the relationship between gender and intraventricular hemorrhage (IVH) in very low birth weight infants (VLBWI) and extremely low birth weight infants (ELBWI).Methods From January 1,1999 to December 31,2012,data on VLBWI and ELBWI,who were admitted to the neonatal intensive care unit of Yuying Children's Hospital within 14 d after birth,were retrospectively collected.The Chi-square test and t test were used to compare neonatal outcomes between male and female infants.The Logistic model was used to analyze the risk factors for IVH.Results A total of 1 008 cases were enrolled,including 615 males and 393 females,895 VLBWI and 113 ELBWI.The incidence of IVH was 15.1% (152/1 008) and the incidence of severe IVH was 8.4% (85/1 008).Compared with females,males had a higher total incidence of IVH [17.2% (106/615) vs 11.7% (46/393),x2=5.728,P<0.05] and severe IVH [9.8% (60/615) vs 6.4% (25/393),x2=3.896,P<0.05].These differences were also seen in VLBWI with a birth weight of 1 250 to 1 499 g [IVH:13.7% (47/344) vs 7.8% (17/217),x2=4.473,P=0.034; severe IVH:7.6% (26/344) vs 2.8% (6/217),x2=5.684,P=0.017].Logistic regression analysis showed that the risk factors for IVH were as follows:gestational age <28 weeks (aOR=2.012,95%CI:1.288-3.143,P<0.05),neonatal respiratory distress syndrome (aOR=l.584,95%CI:1.007-2.492,P<0.05),invasive mechanical ventilation (aOR=2.743,95%CI:1.826-4.121,P<0.05),electrolyte disturbance (aOR=2.128,95%CI:1.092-4.149,P<0.05) and periventricular leukomalacia (aOR=2.901,95%CI:1.312-6.416,P<0.05),but not male sex (aOR=1.351,95%CI:0.917-1.991,P=0.128).The risk factors for severe IVH were gestational age <28 weeks (aOR=2.200,95%CI:1.305-3.708,P<0.05),invasive mechanical ventilation (aOR=4.714,95%CI:2.809-7.911,P<0.05) and electrolyte disturbance (aOR=2.232,95%CI:1.047 4.759,P<0.05),but not male sex (aOR=1.361,95%CI:0.823 2.252,P=0.247).Conclusions Male VLBWI and ELBWI have a higher incidence of IVH and severe IVH,but male sex is not a risk factor for IVH or severe IVH.