1.The effectiveness of glycosylated hemoglobin, fructosamine in the diagnosis of diabetes.
Eun Hee KIM ; Sun Mi NAM ; Kun A LEE ; Bo Young SON ; Kun Mi LEE ; Sung Pill JEONG ; Hyeung Ill KIM
Journal of the Korean Academy of Family Medicine 1998;19(9):708-718
BACKGROUND: With respect to the risk of developing diabetic vascular complications, the central purpose of most screening and detection program, is to identify people with diabetes at early stage so they might have advantages of early treatment to prevent complication of the disease. Oral glucose tolerence test(OGTT) is widely used for diagnosis of diabetes and impaired glucose tolerence, bit the performance of a complete OGTT is not only time consuming and expensive but physically demanding on the individual being tested. Determination of HbA1 and more recently of glycosylated total serum proteins(fructosamine) has been proposed as an alternative method of screening and diagnosis. The aim of our cross-sectional study is to compare the values of fructosamine and HbA1, for the ourpose of diabetes diagnosis with the OGTT as reference method. METHODS: In the study, from January 1996 to August 1996, we included 55 consecutive subjects in Kyeungssang Hospital. Blood samples for HbA1 and fructosamone determination were drawn at the same time as a fasting plasma glucose sample, and then all subjects underwent a standard 2-hour OGTT according to the World Health Organization recom-mandations, The subjects were classified according to the American Diabetes Association classification. RESULTS: In our study, we observed fasting plasma glucose of 145.32+/-75.00mg/deciliter, two-hour plasma glucose of 245.83+/-155.22mg/deciliter, HbA1 of 7.06+/-2.77%, and fructosamine of 308.77+/-128.23 micromol/liter. The correlation coefficient between FPG and HbA1 was 0.9098(p<.05), between FPG and fructosamine 0.7953(p05). between two-hour plasma glucose and HbA1 0.7955-(p<.05), between 2h-PG and fructosamine 0.7770(p<.05), and between HbA1 and fructosamine with OGTT as a reference. After combination of FPG ir 2h-PG and HbA1 especially fructosamine, sensitivity was increased, Receiver operating characteristic curves showed the cutoff point of HbA1 7.0mg/deciliter, of fructosamine 290 micromol/liter. CONCLUSION: As observed in our study, HbA1 and fructosamine were highly correlated with FPG and 2h-PG. Combination of HbA1 or fructosamine and FPG or 2h-PG improve prediction over FPG or 2h-PG alone, especially fructosamine and FPG or 2h-PG combination. We conclude that measurement of HbA1 or fructosamine may be a useful diagnostic test for diabetes.
Blood Glucose
;
Classification
;
Cross-Sectional Studies
;
Diabetic Angiopathies
;
Diagnosis*
;
Diagnostic Tests, Routine
;
Fasting
;
Fructosamine*
;
Glucose
;
Glucose Tolerance Test
;
Hemoglobin A, Glycosylated*
;
Mass Screening
;
ROC Curve
;
World Health Organization
2.A Clinical Study of Hereditary Spherocytosis.
Ki Ho KIM ; Kun Soo LEE ; Haeng Mi KIM ; Doo Hong AHN
Journal of the Korean Pediatric Society 1990;33(1):81-87
No abstract available.
3.Early Extubation after Open Heart Surgery for Congeaital Heart Disease.
Choon Kun CHUNG ; Sang Dong LEE
Korean Journal of Anesthesiology 1987;20(3):349-353
We have experienced early extubation after 20 consecutive open heart surgeries for congenital heart disease between May 19 th and May 30 th this year. Eighteen of those 20 had the tracheal tube removed in the operating room immediately after operation. The reanlts were good and satisfactory. Two required postoperative ventilatory support for several hours at RICU. Sufentanil (Sufenta) 10-15 ug/kg was used intravenously as a major narcotic anesthetic for 18 podiatric patients and Fentanyl 50 ug/kg used for 2 adult Patients. The advantages of early extubation are as follows ; It is more physiologic, more comfortable, psychologically leas anxiety provoking for the patients and has less chance of pulmonary infection and less chance of ventilator mishaps arid it also shortens RICU stay and hospitalization. It is concluded that early extubation after open heart surgery for congenital heart disease has minimal risk and definite advantages in carefully selected patients.
Adult
;
Anxiety
;
Fentanyl
;
Heart Defects, Congenital
;
Heart Diseases*
;
Heart*
;
Hospitalization
;
Humans
;
Operating Rooms
;
Sufentanil
;
Thoracic Surgery*
;
Ventilators, Mechanical
4.Subclavian Vein Catherization for Cardiac Surgery in Children .
Choon Kun CHUNG ; Sang Dong LEE
Korean Journal of Anesthesiology 1987;20(2):204-207
Subclavian vein catheterization is a well estab1ished technique in adults for central venous pressure monitoring and the infusion of irritant solutions. Its use in small children is less common, preaumably because of technical difficulties in inserting the catheter and the disk of major complications. During cardiac surgery heparinization potentially adds to the risk of hematoma forma-tion. But it is often preferred becauae of the greater stability of the catheter on the anterior chest wall and allows a greater freedom of the neck and upper limb movement. We have experienced 62 open heart surgeries for congenital heart disease between April 14th and Oecember 31th 1986. In 47 children ranging in age from 11 months to 15 years, there was a high succes rate and no morbidity. It is concluded that infraclavicular subclavian vein catheterization is a useful means of measuring central venous presaure and establishing a central infusion line in children undergoing open heart surgery.
Adult
;
Catheterization
;
Catheters
;
Central Venous Pressure
;
Child*
;
Freedom
;
Heart
;
Heart Defects, Congenital
;
Hematoma
;
Heparin
;
Humans
;
Neck
;
Subclavian Vein*
;
Thoracic Surgery*
;
Thoracic Wall
;
Upper Extremity
5.The cases of ovarian pregnancy.
Kyu Ho JEUNG ; Yong Mi LEE ; Young Kun YOO ; Kyu Hong CHOI
Korean Journal of Obstetrics and Gynecology 1993;36(7):2010-2014
No abstract available.
Female
;
Pregnancy
;
Pregnancy, Ectopic*
6.Postoperative Airway Obstruction in a Patient With Huge Mediastinal Hemangioam.
So Young CHUNG ; Yong Sung HAN ; Mi Ra LEE ; Hong Sik LEE ; Choon Kun CHUNG ; Dong Ho PARK
Korean Journal of Anesthesiology 1992;25(5):1028-1033
Anesthesia for the patients with mediastinal mass may be associated with significant respiratory and cardiovaacular complications due to compression of traeheobronchial trees, the pulmonary artery, heart and superior vena cava The authors present a case of a 6-year-old girl with a large mediastinal tumor located in anterior and superior mediaetinum. Preoperatively, the patient was asymptomatic and anesthesia was induced and maintained uneventfully. Operative finding was that 8 X 14 cm sized hemangioma was extended superiorly over thoracic outlet, posteriorly aorta and SVC, medially pericardium and right hilum and inferiorly right upper lung and pleura. Because difficulties in removal of the hemangioma were expected, exploratory thoracotomy was discontinued. On emergence, as soon as the patient was extubated due to irritability, the patient became cyanotic and was noticed bulging mass on right supraclavicular area, Intubation was attempted and during direct laryngoscopy, anesthesiologist also noticed a bulging mass in right oral cavity. Postoperatively, the patients airway was kept with endotracheal tube, but cyanosis appeared on the face and skin over the chest, but not below the abdomen. Bulging mass on right supraclavicular area, distension of neck vein and conjunctival edema were noticed only when the patient was crying or suctioned. Symptoms improved by deep sedation. We assumed that enlargement of hemangioma due to increased central blood volume occasionally compressed tracheobronchial tree and sup. vena cava when patient was irritable, crying and coughing. On 11th postoperative day, patient was transferred to the another hospital for the better treatment with endotracheal intubation.
Abdomen
;
Airway Obstruction*
;
Anesthesia
;
Aorta
;
Blood Volume
;
Child
;
Cough
;
Crying
;
Cyanosis
;
Deep Sedation
;
Edema
;
Female
;
Heart
;
Hemangioma
;
Humans
;
Intubation
;
Intubation, Intratracheal
;
Laryngoscopy
;
Lung
;
Mouth
;
Neck
;
Pericardium
;
Pleura
;
Pulmonary Artery
;
Skin
;
Suction
;
Thoracotomy
;
Thorax
;
Veins
;
Vena Cava, Superior
7.Differences in Clinical Laboratory Data between the Elderly and the Young Adults.
Kun A LEE ; Keun Mi LEE ; Seung Pil JUNG ; Seong Wook BAE
Yeungnam University Journal of Medicine 1997;14(2):430-442
Due to the lowering of biological functions resulted from old age, the elderly is known to have many different clinical laboratory data compared with the young adults. But, in korea, such study is lacking. This research is to find the differences between the elderly and the young adults, and also to know the sexual differences, by comparing the outcomes of the clinical laboratory data. Along with that, it is to help clinical usage of the data in the future. The age of the elderly was between 60 and 83(average age 63.8), and that of the young controls was between 20 and 35. In both sexes, MCV, MCH, ESR, CRP,AST, ALT, gamma GTP, ALP, BUN, total cholesterol were significantly higher in the elderly than in the controls. And lymphocyte count(%), total bilirubin, direct bilirubin, total protein, albumin, T3 were significantly lower in the elderly than in the controls(P<0.05). Hemoglobin, Hct, platelet count, T4 were significantly lower only in the male elderly, and eosinophil count(%), creatinine were significantly higher only in the female elderly(P<0.05). HDLcholesterol was significantly higher only in the male elderly(P<0.01). There were no significant difference between two groups regarding WBCcount, segment neutrophil count(%), monocyte count(%), TSH. Many clinical laboratory data are different between the elderly and the young adults, and some clinical laboratory data also have sexual differences.
Aged*
;
Bilirubin
;
Cholesterol
;
Creatinine
;
Eosinophils
;
Female
;
Guanosine Triphosphate
;
Humans
;
Korea
;
Lymphocytes
;
Male
;
Monocytes
;
Neutrophils
;
Platelet Count
;
Young Adult*
8.Effects of a Full Body Massage on Uterine Contraction, Length of Labor, Type of Delivery, and Drug Intervention for Primipara during Labor.
Kun Ja LEE ; Chun Ja CHANG ; Hyun Sook JO ; Mi Ran KIM
Korean Journal of Women Health Nursing 2002;8(4):538-549
This study was designed to test the effects of a full body massage on uterine contraction, length of labor, type of delivery, and drug intervention for primipara during labor. Data were collected using a quasi-experiment method (nonequivalent control group, pre-post test design) from November 1, 2001 to July 31, 2002. The subjects of this experiment consisted of 28 women in the experimental group and 29 in the control group, out of 57 primipara hospitalized at the U OB & GYN hospital in Inchon. The experimental group was given a 20 minute full body massage for each of the three delivery phases (latent, active, and transition). The control group was given conventional delivery care. Three (3) parameters were analyzed in this experiment. (1) The interval, duration, and strength of uterine contraction, using an electric tocodynamometer (2) The elapsed time for stage 1 and stage 2 labor. (3) The types of deliveries and drug interventions, using postpartum medical records The data collected were analyzed using the repeated measures analysis of variance (ANOVA), t-test, and X(2) test of the SPSS program. The results of the experiment are as follows: 1) Uterine contraction interval was signifi- cantly reduced (F=3.210, p=.050). Duration of uterine contraction showed significant increase only during the transition phase (t=-2.319, p=.023). Strength of uterine contraction showed no significant difference. 2) Total length of labor was significantly shortened (t=-5.245, p=.000). The length of 1st stage labor was signifi- cantly shortened (t=-5.164, p=.000), with latent phase showing (t=-4.709, p=.000), active phase (t=-2.973, p=.005), and transition phase (t=-2.031, p=.047). The length of 2nd stage labor showed no significant difference. 3) The number of natural deliveries were significantly increased (X(2)=13.127, p=.004). 4) The number of drug interventions were significantly fewer (X(2)= 4.493, p=.034). In conclusion, this study shows that a full body massage has a significantly positive effect on uterine contraction interval, length of labor, type of delivery, and drug intervention. Therefore, this study suggests that a full body massage be used clinically to help primipara during labor.
Evaluation Studies as Topic
;
Female
;
Humans
;
Incheon
;
Massage*
;
Medical Records
;
Postpartum Period
;
Uterine Contraction*
9.Significance of Aseptic Room Reverse Isolation in Febrile Neutropenic Cancer Patients.
Young Mi KIM ; Hyun Ji SEO ; Kun Soo LEE
Korean Journal of Pediatric Hematology-Oncology 2005;12(2):317-324
PURPOSE: The aim of this study is to find out the role of HEPA filter equipped lamina air flow room reverse isolation for the treatment of anticancer drug induced febrile neutropenic patients. METHODS: Antibiotics and antifungal agents were promptly administered to twenty six patients with febrile neutropenic following chemotherapy from January 2003 to July 2005 at the Department of Pediatrics, Kyungpook National University Hospital, Daegu, Korea. And if possible, they were treated in the aseptic room. RESULTS: Nineteen patients recovered and seven patients died of infectious causes among twenty six patients. Fourteen patients had microbiologically defined infection, seven patients had clinically defined infection, and five patients had unexplained fever. The causes of infection were sepsis, pneumonia and urinary tract infection. The etiologic pathogens were Gram negative bacilli, 6 (42.9%) ; Gram positive cocci, 3 (21.4%) ; and fungus, 5 (35.7%). The dead group showed lower leukocyte count and higher CRP than the survived group. All dead patients showed disseminated intravascular coagulation syndrome (DIC). Nine of the ten patients (90%) who were treated in the aseptic room survived and ten of the sixteen patients (62.5%) in the general ward survived. CONCLUSION: The infection-related mortality of febrile neutropenic patients following chemotherapy is influenced by the early and adequate use of antimicrobial agents, DIC, neutrophil count and CRP. The isolation in the aseptic room increased the survival rate, but it was not statistically significant.
Anti-Bacterial Agents
;
Anti-Infective Agents
;
Antifungal Agents
;
Dacarbazine
;
Daegu
;
Disseminated Intravascular Coagulation
;
Drug Therapy
;
Fever
;
Fungi
;
Gram-Positive Cocci
;
Gyeongsangbuk-do
;
Humans
;
Korea
;
Leukocyte Count
;
Mortality
;
Neutrophils
;
Patients' Rooms
;
Pediatrics
;
Pneumonia
;
Sepsis
;
Survival Rate
;
Urinary Tract Infections
10.A Clinical Study of Splanchnic Nerve Block.
Won Sok CHANG ; Duck Mi YOON ; Youn Woo LEE ; Hung Kun OH
Korean Journal of Anesthesiology 1999;36(2):273-278
BACKGROUND: It is difficult to manage intractable pain from advanced carcinoma of the upper abdomen. One method used to control pain associated with these malignancies is to block the splanchnic nerve. We investigated that VAS (visual analogue scale) difference before and after splanchnic nerve block (SNB) and pain relief day. Also we studied relationship between VAS before SNB and pain relief day. METHODS: A rewiew of 70 patients who took splanchnic nerve block (SNB) from September 1994 to February 1998 was carried out to assess age, sex, primary diseases, pain sites, VAS before and after SNB, date of diagnosis, date of SNB, date of death and pain relief day, etc. RESULTS: Of 70 patients, 44 were males and the remaining 26 were females. The causes of pain were stomach cancer 28 (40%), pancreatic cancer 18 (25%), gall bladder cancer 7 (10%), hepatoma 6 (8.6%) respcectively. Average day from diagnosis to SNB was 272 and average day from diagnosis to death was 341. So, patients died on the average 69 days after they took the splanchnic nerve block in pain clinic. VAS average before SNB was 8.01 and VAS average after SNB was 3.64. Patients felt pain relief during 35 days after SNB. Pain relief day of patients who had lower VAS before SNB was longer than that of patients who had higher VAS before SNB. CONCLUSION: Early application of splanchnic nerve block will make the patients endure the cancer pain more easily.
Abdomen
;
Carcinoma, Hepatocellular
;
Diagnosis
;
Female
;
Gallbladder Neoplasms
;
Humans
;
Male
;
Pain Clinics
;
Pain, Intractable
;
Pancreatic Neoplasms
;
Splanchnic Nerves*
;
Stomach Neoplasms