The teeth present at birth are called natal teeth, while the teeth that appear within the first thirty days following birth are called neonatal teeth. Approximately one in 2,000 to 3,500 infants experiences the eruption of teeth at birth or within the first few weeks postpartum. Many contributing factors have been suggested for the premature eruption of primary teeth. It has been suggested that upon eruption these teeth are of normal structure according to their developmental age, but after eruption, lateral movement in the cervical area leads to disturbance of the dentin and premature degeneration of Hertwig's root sheath. In most cases, they have immature, aborted structures consisting only of caps of enamel, dentin, or a combination of both. A radiograph can show the presence or absence of enamel, dentin, or root structures, as well as supernumerary teeth. These teeth may be aspirated or swallowed during feeding. Discomfort from mobile and erupting teeth often causes the infant to refuse to feed. In addition, a nursing mother's nipples may become lacerated and infected. Extraction is the indicated treatment if these neonatal teeth cause discomfort or demonstrate mobility or incomplete, immature development. Treatment decisions must be made on an individual basis from both clinical and radiographic findings. We report four cases of neonatal teeth in complete cleft lip and palate patients.
Cleft Lip* ; Dental Enamel ; Dentin ; Humans ; Infant ; Natal Teeth ; Nipples ; Nursing ; Palate* ; Parturition ; Postpartum Period ; Tooth* ; Tooth, Deciduous ; Tooth, Supernumerary

No abstract available.
DNA* ; Ploidies* ; Stomach Neoplasms* ; Stomach*

Transcatheter arterial embolization was applied in 7 cases of hepatic disease including hemobilia of various causes and malignant tumors at Department of Radiology, Seoul National University Hospital during recent several years. The embolic materials were autologous blood clot and Gelfoam particle. Successful control of bleeding or devascularization of tumor vessel was made in 6 of the 7 patients. There was no serious complications; however, post embolization syndrome was found including pain, fever, nausea and vomiting in all cases and subsided after a few days. Transcatheter hepatic arterial embolization is suggested to be a safe and effective treatment in control of hemobilia and devascularization of malignant hepatic tumors.
Fever ; Gelatin Sponge, Absorbable ; Hemobilia ; Hemorrhage ; Humans ; Nausea ; Seoul ; Vomiting

Prediction f chemical composition of gallstones is a prerequisite in contemplating the chemical dissolution or extracorporeal shock wave lithotripsy of gallstones. The author retrospectively analysed the correlation between quantitative chemical composition of gallstones and their ultrasonographic and computed tomographic findings. The ultrasonography(US) and computed tomography(CT) of 100 consecutive stones obtained from 100 patients were performed under the in vitro condition. Their US and CT fingings were grouped with certain patterns and each group was compared with the chemical composition of the stones. Stones with entirely discernible cirumsference and homogeneous internal echo on US had high bilirubin and low cholesterol content. Acoustic shadows were frequently absent with those stones. Stones with variable internal echo on US had relatively high cholesterol content but their distribution range were wide. There was no correlationship between the cholesterol content and the CT No. of the gallstones. There was positive correlationship between the calcium content and the CT No. of gallstones. The near totally calcified gallstones had very low cholesterol and high residue content. There was no relationship betweenthe calcification type and the ultrasonographic pattern. In conclusion, those stones with entirely discernible circumsference and homogeneous internal echo on US were pigment stones. On the contrary, stones with variable internal echo had relatively high cholesterol content. CT could predict the calcium content with CT No., but could not predict the cholesterol content.
Acoustics ; Bilirubin ; Calcium ; Cholesterol ; Gallstones* ; Humans ; In Vitro Techniques ; Lithotripsy ; Retrospective Studies ; Shock ; Ultrasonography*

BACKGROUND AND OBJECTIVES: The growing implantations of electrophysiological devices in the context of increasing rates of chronic antithrombotic therapy in cardiovascular disease patients underscore the importance of an effective periprocedural prophylactic strategy for prevention of bleeding complications. We assessed the risk of significant bleeding complications in patients receiving anti-platelet agents or anticoagulants at the time of permanent pacemaker (PPM) implantation. SUBJECTS AND METHODS: We reviewed bleeding complications in patients undergoing PPM implantation. The use of aspirin or clopidogrel was defined as having taking drugs within 5 days of the procedure and warfarin was changed to heparin before the procedure. A significant bleeding complication was defined as a bleeding incident requiring pocket exploration or blood transfusion. RESULTS: Permanent pacemaker implantations were performed in 164 men and 96 women. The mean patient age was 73+/-11 years old. Among the 260 patients, 14 patients took warfarin (in all of them, warfarin was changed to heparin at least 3 days before procedure), 54 patients took aspirin, 4 patients took clopidogrel, and 25 patients took both. Significant bleeding complications occurred in 8 patients (3.1%), all of them were patients with heparin bridging (p<0.0001). Heparin bridging markedly increased the length of required hospital stay when compare with other groups and the 4 patients (1.5%) that underwent the pocket revision for treatment of hematoma. CONCLUSION: This study suggests that hematoma formation after PPM implantation was rare, even among those who had taken the anti-platelet agents. The significant bleeding complications frequently occurred in patients with heparin bridging therapy. Therefore, heparin bridging therapy was deemed as high risk for significant bleeding complication in PPM implantation.
Anticoagulants ; Aspirin ; Cardiovascular Diseases ; Female ; Hematoma ; Hemorrhage ; Heparin ; Humans ; Length of Stay ; Male ; Ticlopidine ; Warfarin

gamma-Glutamyltransferase(GGT: E.C. 2.3.2.2.) is a glycoprotein enzyme which is involved in glutathione metabolism and amino acid transport through the plasma membrane. It is distributed widely in several organs including liver, kidney, pancrease and brain. GGTs derived from the brain of Wister rats and BALB/c mice were biochemically purified to a specific activity of 4246.2, 862.1 units per mg of protein, a purification folds 93.7, 43.8 and the final yield 65.8, 44.0% respectively. Electrophoretic pattern of purified GGTs from rats and mice brain shows very similar protein fraction each other. We have produced six monoclonal antibodies(GGT-Mab 1-6) against 2-acetamidogluorene treated rat liver GGT. Using these GGT-Mab 1-6 we performed immunohistochemistry(IHC) to study the distribution of GGT isozymes in normal tissues of rat brain and in neoplastic tissues of human brain. The results indicated that human brain GGT was localized in pericytes of blood-brain barrier, especially in the blood-rich portion of the brain(e.g. cerebellum of rat, meningioma and craniopharyngioma of human). Therefore these Maps may be used to evaluate the distribution of GGT isozymes in different tissues.
Animals ; Antibodies* ; Antibodies, Monoclonal ; Blood-Brain Barrier* ; Brain ; Cell Membrane ; Cerebellum ; Craniopharyngioma ; gamma-Glutamyltransferase* ; Glutathione ; Glycoproteins ; Humans ; Isoenzymes ; Kidney ; Liver ; Meningioma ; Metabolism ; Mice ; Pancreas ; Pancrelipase ; Pericytes* ; Rats

Though intravenous digital subtraction angiography (IV DSA) has several advantages over conventionalangiography in diagnosis and follow up of various vascular disease, it also has several undesirable problems suchas large volume of the contrast medium and inferior image quality compared to conventional angiography. Sorecently intraarterial digital subtraction angiography (IA DSA) was introduced for better image quality usingsmall amount of contrast medium. The authours had good clinical results IA DSA which were made in 20 patients withour own system, SRM-II, developed by cooperation of Departements of Radiology and Medical engineering, Seoul.National University Hospital. Intraarterial digital substraction angiography was found to have several advantagesover conventional angiography: (a) small amount of contrast medium, (b) reduced need for selective arterialcatheterization,(c) lower film cost, (d) shortened examination time, (e) ability to obtain a “road map”, and (f)easier detection of contrast medium. Also IA DSA has several advantages over IV DSA : (a) less dependency oncardiac output, (b) far less vessel overlapping, (c) reduction in patient motion through less painful procedure byreduced volume of contrast media and shorter imaging time.
Angiography ; Angiography, Digital Subtraction ; Contrast Media ; Diagnosis ; Follow-Up Studies ; Humans ; Vascular Diseases

We investigated the overall survival rate after pulmonary metastasectomy in the bone and soft tissue sarcoma and the available prognostic factors related with the survival rate after pulmonary metastasectomy. Between 1986 and 1995, 9 patients (median age 32) with bone and soft tissue sarcoma with pulmonary metastasis were managed in the Catholic University of Korea. Until the final follow-up in May 1996, 6 patients have died of disease and their mean survival period was 28 months (9- 58months). The actual 5-year survival rate by Kaplan-Meier method was 33%. Prognostic factors such as tumor free interval, number of metastatic lesion, postoperative chemotherapy and histologic grade were analyzed. Three patients who had the tumor free interval over 3 years were alive (mean survival period: 52.6 months), whereas six patients who had the tumor free interval less than 3 years were dead (mean survival period: 19 months). Out of four patients with low grade tumor, three patients were alive with average 39.2 months survival period, whereas five patients with high grade tumor were all dead with average 19.2 months survival period. These results suggested that pulmonary metastasectomy in bone and soft tissue sarcoma may prolong the survival rate. The long tumor free interval, histological low grade and soft tissue sarcoma may influenced on prolonged survival rate. However, number of metastatic lesion or postoperative chemotherapy has not influenced on the survival rate.
Drug Therapy ; Follow-Up Studies ; Humans ; Korea ; Metastasectomy* ; Neoplasm Metastasis ; Sarcoma* ; Survival Rate*

The clinical and pathological features were analyzed for 11 cases with intracranial ependymoma treated surgically at the Keimyung University Dongsan Medical Center during the years 1987 to 1992. Tumor histology was reviewed individually and grouped into three categories(Categories I to III) according to the pathologic grade used by Nazar, et al. There were 2 cases(18%) with category I histology, 5(45%) with category II histology, and 4(36%) with category III histology. The high recurrent rate, short recurrent interval, high rate of cerebrospinal fluid seeding and poor outcome were noted in patients with category III histology. The authors also investigated the recurrent interval according to the degree of tumor resection. The mean recurrent interval after surgery was 12 months in cases of subtotal resection and 33 months in a case of total resection. Tumors resected subtotally showed response to radiation and chemotherapy. In conclusion, the pathologic grade and the degree of tumor resection were regarded as important prognostic factors after surgery. Aggressive surgery with chemotherapy or radiotherapy were required in the management of intracranial ependymoma.
Cerebrospinal Fluid ; Drug Therapy ; Ependymoma* ; Humans ; Prognosis ; Radiotherapy

No abstract available.
Calcium*