95 %viability .Histaminesecretionismeasuredbyenzymeimmunoassay .Basalsecretionwas (0 .6 ? 0 .2 )nmol/ 10 3cell.GastrinstimulatedhistaminesecretionwithEC50 of 3? 10 -10 mol/Landwasinhibited bypretreatmentofgastrinreceptorantagonistL3652 66,(IC50 10 -8mol/L) .TheDNAsynthesisofECLcell wasdeterminedbyBrdU .GastrinstimulatedECLcellDNAsynthesiswithEC50 of 2? 10 -11mol/L . ConclusionAboveresultsindicatedthatECLcellcouldlivewellinculturesystemandprovideagoodmeansfor investigatingcentralroleofECLcellfunction .
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