1.Alkaloids and lignans from stems of Piper betle.
Xiangzhong HUANG ; Yan YIN ; Wenquan HUANG ; Kuizong SUN ; Chunmei CHENG ; Lian BAI ; Yun DAI
China Journal of Chinese Materia Medica 2010;35(17):2285-2288
Alkaloids and lignans from the stems of Piper betle were studied. Compounds were isolated and purified by repeated silica gel, reverse phase silica gel, Sephadex LH-20 column chromatography and preparative thin layer chromatography. The structures were elucidated on the basis of spectral analysis. From the ethyl acetate soluble fractions of the 70% acetone extract, ten compounds were isolated and identified as piperine (1), pellitorine (2), N-isobutyl-2E,4E-dodecadienamide (3), dehydropipernonaline (4), piperdardine (5), piperolein-B (6), guineensine (7), (2E,4E)-N-isobutyl-7-(3',4'-methylenedioxyphenyl)-2,4-heptadienamide (8), syringaresinol-O-beta-D-glucopyranoside (9),pinoresinol (10). All Compounds were isolated from the plant for the first time, and compounds 9 and 10 were isolated firstly from the genus.
Alkaloids
;
analysis
;
isolation & purification
;
Chromatography, Thin Layer
;
Lignans
;
analysis
;
isolation & purification
;
Piper betle
;
chemistry
;
Plant Stems
;
chemistry