1. Effect of flow diverting stents on the abdominal aorta in rabbits
Chinese Journal of Cerebrovascular Diseases 2011;8(2):91-95
Objectives: To observe the radiological and pathological changes of flow diverting sent implanting into abdominal aortae of rabbits at 3 months and to evaluate the safety of stents for normal arteries of rabbits. Methods: The abdominal aorta beyond the left renal artery opening was showed via preoperative angiography. The flow diverting stents with metal coverage of 35% to 45% were implanted into the abdominal aortae of 20 New Zealand white rabbits. Intravenous digital subtraction angiography was performed at 4 weeks after the procedure. Arterial digital subtraction angiography was performed for all the animals at 3 months and they were sacrificed for histopathological examination. The angiography showed that the diameter changes of abdominal aortae on the stenting sites at different time points were measured and compared. The relationship between the neointima and the metal coverage of local stent were analyzed. Results: The mean diameter of the abdominal aortae before stenting, immediately after stenting, at 4 weeks, and at 3 months were 3.47 ± 0.44 mm, 3.65 ± 0.40 mm, 3.57 ± 0.36 mm, and 3.51 ± 0.30 mm, respectively. There were significant differences among the different time points (P=0.009). The neointima fully covered the stents with a mean thickness of 95 ± 42 μm. They were predominantly composed of smooth muscle cells, collagen fibers, and a small amount of macrophages. The neointimal thickness was positively correlated with the local coverage of the metal stents (r = 0.523; P = 0.001). Conclusion Three months after the implantation of flow diverting stents, the abdominal aorta intima thickened slightly, and the stents were safety for normal arteries of rabbits.
2.Effects of low calcium concentration dialysate on blood pressure,ionized calcium and serum endothelin-1 of uremic patient with hypertension during hemodialysis
Dajun LIU ; Zhong WANG ; Detian LI ; Kui LIU
Chinese Journal of Practical Internal Medicine 2001;0(06):-
Objective To evalute effects of low calcium concentration dialysate on blood pressure,ionized calcium and serum endothelin-1 of uremic patient with hypertension during hemodialysis.Methods 60 uremic patients with hypertension during hemodialysis in the Shengjing Hospital of China Medical University were dialysated with different calcium concentration(1.75 mmol/L followed by 1.25 mmol/L).TO measurearterial blood pressure,ionized calcium and serum endothelin-1 before and after each dialysis session.Results The post-dialysis blood pressure,ionized calcium and serum endothelin-1 level of uremic patients using DCa1.75 with hypertension during hemodialysis were increased significantly than those of pre-dialysis and post-dialysis with DCa1.25(P
3.Transformer winding's temperature rising and an analysis of its uncertainty.
Pei-Lian WANG ; Yu-En CHEN ; Sheng-Kui ZHONG
Chinese Journal of Medical Instrumentation 2007;31(5):367-370
This paper introduces the temperature rising experimental process and some matters needing attention when the transformer is normally loading. And an analysis of the uncertainty for transformer's temperature rising is also made based on the practical examples' data.
Electricity
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Equipment Safety
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Temperature
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Uncertainty
5.Clinical application of free upper limb lateral bone-skin flap in hand surgery field
Zhen-Zhong SUN ; Kui-Shui SHOU ; Xu-Ming WEI ; Jian-Bing WANG ; Yong-Wei WU ; San-Jun GU
Chinese Journal of Microsurgery 2000;0(02):-
Objective To report the surgical method and treatment outecome of transfer of free upper limb lateral bone-skin flap for repair of bone defects and nonunion in hand and forearm.Methods 17 cases of hand composite trauma,5 cases of forearm composite trauma and 2 cases of nonunion in forearm were treated with free bone-skin flaps in distal humerus,whose pedicle was the posterior branch of radical collateral artery. Area of the flap was 2cm?3cm to 8cm?10cm,length of exseeted bone was 3~6 cm.Results All the bone-skin flaps completely survived,the donor area all achieved primary healing,On postoperative 1~4 years follow-up,the texture of the flap was excellent,and bone union was obtained in all transplants,the donor area of distal lateral humerus became thicker and thicker with new cortical bones formed.According to the upper arm function assessment criterion issued by hand surgery association of Chinese medical association.The hand function had excellent results in 17 cases and good results in 2 cases.Conclusion The bone-skin flap has following advantages:easy dissection,reliable blood supply,and no major vessel needed to be sacrificed,so it is an effective method for repair of skin and soft tissue with bone defects in hand and forearm,It.also can be used to repair refractory nonunion in ulna and radius.
6.Study on the Yersinia pestis plasmid along the Qinghai-Tibet Railway
Chun-hua, ZHANG ; Jing-sheng, L(U) ; Bin, ZHAO ; Xian-bin, CONG ; Zhong-hui, WANG ; Shi, ZHANG ; Kui-dong, SHAO
Chinese Journal of Endemiology 2008;27(6):595-597
Objective To detect the Yersinia pestis plasmid and molecular weight along the Qinghai-Tibet Railway.Methods Yersinia pestis plasmids molecular weight detected and analyzed using alkaline lysis,phenol-chloroform extraction of Yersinia pestis plasmid by agarose gel electrophoresis.Results The 18 Yersinia pestis strains of Qinghai-Tibet Railway contained 6×106,45×106,52×106,65×106,92×106plasmid,varing in the range of the 52×106-92×106.Conclusions The Yersinia pestis of Qinghai-Tibet Railway has a standardplasmid graphics,with the biggest Yersinia pestis plasmid changing in a certain regular degree,which providessignificance in the study of plague natural foci of the spatial structure and the genetic.characteristics of Yersiniapestis.
7.Comments on Nigel Wiseman's "A Practical Sictionary of Chinese Medicine"--on Wiseman' s literal translation.
Zhu-fan XIE ; Gan-zhong LIU ; Wei-bo LU ; Tingyu FANG ; Qingrong ZHANG ; Tai WANG ; Kui WANG
Chinese Journal of Integrated Traditional and Western Medicine 2005;25(10):937-940
Comments were made on the word-for-word literal translation method used by Mr. Nigel Wiseman in A Practical Dictionary of Chinese Medicine. He believes that only literal translation can reflect Chinese medical concepts accurately. The so-called "word-for-word" translation is actually "English-word-for-Chinese-character" translation. First, he made a list of Single Characters with English Equivalents, and then he replaced each character of Chinese medical terms with the assigned English equivalent. Many English terms thus produced are confusing. The defect of the word-for-word literal translation stems from the erroneous idea that the single character constitutes the basic element of meaning corresponding to the notion of "word" in English, and the meaning of a disyllabic or polysyllabic Chinese word is simply the addition of the meanings of the two or more characters. Another big mistake is the negligence of the polysemy of Chinese characters. One or two English equivalents can by no means cover all the various meanings of a polysemous character as a monosyllabic word. Various examples were cited from this dictionary to illustrate the mistakes.
Medicine, Chinese Traditional
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Terminology as Topic
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Translations
8.Animal study for airway inflammation triggered by gastroesophageal reflux.
Yun-gang LAI ; Zhong-gao WANG ; Feng JI ; Ji-min WU ; Xiu CHEN ; Zhen LI ; Shu-kui DONG
Chinese Medical Journal 2009;122(22):2775-2778
BACKGROUNDGastroesophageal reflux disease with extra-esophageal symptoms, especially those with respiratory distress was attracting more and more attention. The related mechanisms were still in controversy. The purpose of the work was to explore airway inflammation triggered by gastroesophageal reflux.
METHODSSixteen Sprague-Dawley rats were used as study group and 9 as control. In the study group, a plastic extender with a trumpet-shaped distal end was inserted into the lower esophagus to dilate the cardia, the pylorus was ligated. One ml of 0.1 mol/L hydrochloric acid was injected into the stomach. While a simple laparotomy was performed for control animals. All animals from two groups were sacrificed 24 hours after operation. Then tracheotomy was carried and the bronchoalveolar lavage fluid was collected in all animals. Cells in the fluid were counted and levels of interleukin (IL)-5, -6, -8 in it were measured.
RESULTSCompared with control group, the study group presented a neutrophil pattern of airway inflammation and an elevated concentration of IL-5, -6, -8 with no significant difference regarding eosinophil count.
CONCLUSIONThe gastroesophageal reflux-triggered airway inflammation is characterized by a neutrophilic airway inflammation which differed from that caused by asthma, and enhanced levels of IL-5, -6 and -8, which are similar to that caused by asthma.
Animals ; Asthma ; etiology ; Bronchoalveolar Lavage Fluid ; immunology ; Disease Models, Animal ; Female ; Gastroesophageal Reflux ; complications ; Inflammation ; etiology ; Interleukin-5 ; analysis ; Interleukin-6 ; analysis ; Interleukin-8 ; analysis ; Male ; Rats ; Rats, Sprague-Dawley
10.Analysis of methicillin resistant Staphylococcus aureus in burn ward of Ruijin hospital.
Wen-Kui WANG ; Li-Zhong HAN ; Li YANG ; Xiao-Qin HUANG ; Yu-Xing NI
Chinese Journal of Burns 2007;23(2):97-99
OBJECTIVETo analyze the epidemiology of methicillin resistant Staphylococcus aureus (MRSA) in molecular level in burn centre of Shanghai Ruijin hospital.
METHODSThe vicissitude of Staphylococcus aureus in the burn centre from 2003 to 2005 was analyzed with software WHONET5. Multiprimer random amplified polymorphic DNA(RAPD) was used to analyze the homology of 17 MRSA strains.
RESULTSRAPD analysis (primer ERIC2 and RAPD7) showed that all 17 MRSA strains were identical (Burn-A type).
CONCLUSIONMRSA with same RAPD type is prevalent in our burn centre for many years, so emphasis should be laid on the anti-infection therapy and its cross infection control. Staphylococcus aureus;
Burn Units ; Humans ; Methicillin-Resistant Staphylococcus aureus ; drug effects ; genetics ; isolation & purification ; Microbial Sensitivity Tests ; Random Amplified Polymorphic DNA Technique ; Sequence Homology ; Staphylococcal Infections ; drug therapy ; microbiology