1.Analysis of the diagnosis of occupational radiation diseases in Hubei Province, China, 1986-2021
Jing WANG ; Ying XIA ; Kui MA ; Liangying MEI ; Yingping GAO
Chinese Journal of Radiological Health 2025;34(6):846-849
Objective To analyze the diagnosis of occupational radiation diseases in Hubei Province, China between 1986 and 2021, and to assess the occupational health risks of radiation workers in Hubei Province. Methods A retrospective analysis was conducted on the diagnosis institutions, diagnosis case characteristics, and typical problems encountered in the diagnosis process of occupational radiation diseases in Hubei Province between 1986 and 2021. The findings were analyzed and discussed in conjunction with current occupational disease diagnosis standards and relevant regulations. Results There are currently 3 authorized occupational radiation disease diagnosis institutions in Hubei Province, with a total of 14 diagnostic physicians. Among them, 9 (64.3%) have senior professional titles and 12 (85.7%) possess postgraduate degrees; however, only one has a professional background in radiological medicine. From 1986 to 2021, a total of 139 cases of occupational radiation diseases were diagnosed. Chronic radiation sickness from external exposure accounted for 40.3%, radiation-induced cataract for 21.6%, and radiation-induced tumors for 18.7%. Among all cases, 81.4% were engaged in diagnostic radiology and interventional radiology, 3.1% were engaged in radiotherapy, and 3.1% were engaged in nuclear medicine. Diagnosed cases were primarily concentrated among medical radiation workers, especially those involved in X-ray diagnosis. Issues identified during the diagnosis process included illegal acceptance of subjects, non-standard dosage estimation, and illegal procedures. Conclusion The incidence of occupational radiation diseases in Hubei Province showed a declining trend. The diagnosis of occupational radiation diseases needs to be improved, and the occupational health management of key radiation workers should be further strengthened.
2.Comparison of Direct and Extraction Immunoassay Methods With Liquid Chromatography-Tandem Mass Spectrometry Measurement of Urinary Free Cortisol for the Diagnosis of Cushing’s Syndrome
Danni MU ; Jiadan FANG ; Songlin YU ; Yichen MA ; Jin CHENG ; Yingying HU ; Ailing SONG ; Fang ZHAO ; Qi ZHANG ; Zhihong QI ; Kui ZHANG ; Liangyu XIA ; Ling QIU ; Huijuan ZHU ; Xinqi CHENG
Annals of Laboratory Medicine 2024;44(1):29-37
Background:
Twenty-four-hour urinary free cortisol (UFC) measurement is the initial diagnostic test for Cushing’s syndrome (CS). We compared UFC determination by both direct and extraction immunoassays using Abbott Architect, Siemens Atellica Solution, and Beckman DxI800 with liquid chromatography-tandem mass spectrometry (LC-MS/MS). In addition, we evaluated the value of 24-hr UFC measured by six methods for diagnosing CS.
Methods:
Residual 24-hr urine samples of 94 CS and 246 non-CS patients were collected.A laboratory-developed LC-MS/MS method was used as reference. UFC was measured by direct assays (D) using Abbott, Siemens, and Beckman platforms and by extraction assays (E) using Siemens and Beckman platforms. Method was compared using Passing–Bablok regression and Bland–Altman plot analyses. Cut-off values for the six assays and corresponding sensitivities and specificities were calculated by ROC analysis.
Results:
Abbott-D, Beckman-E, Siemens-E, and Siemens-D showed strong correlations with LC-MS/MS (Spearman coefficient r = 0.965, 0.922, 0.922, and 0.897, respectively), while Beckman-D showed weaker correlation (r = 0.755). All immunoassays showed proportionally positive bias. The areas under the curve were 0.975 for Abbott-D, 0.972 for LCMS/MS, 0.966 for Siemens-E, 0.948 for Siemens-D, 0.955 for Beckman-E, and 0.877 for Beckman-D. The cut-off values varied significantly (154.8–1,321.5 nmol/24 hrs). Assay sensitivity and specificity ranged from 76.1% to 93.2% and from 93.0% to 97.1%, respectively.
Conclusions
Commercially available immunoassays for measuring UFC show different levels of analytical consistency compared to LC-MS/MS. Abbott-D, Siemens-E, and Beckman-E have high diagnostic accuracy for CS.
3.Evidence-based practice of non-invasive mechanical ventilation related pressure injury prevention guided by the integrated promoting action on research implementation in health services framework
Xia WANG ; Haiyan WANG ; Kui SONG ; Xuelian WANG ; Shengxiao NIE ; Hong GUO
Chinese Journal of Practical Nursing 2024;40(8):568-575
Objective:To use the best evidence of noninvasive mechanical ventilation related pressure injury prevention in the clinic guided by integrated promoting action on research implementation in health services framework (i-PARIHS) and evaluate its effect.Methods:This study is an unsynchronized before and after control study. Convenience sampling method was used to select patients receiving non-invasive mechanical ventilation from 7 wards of Beijing Hospital from October 2019 to September 2021. A total of 575 patients receiving non-invasive mechanical ventilation from October 2019 to September 2020 were included in the control group and 602 patients from October 2020 to September 2021 were included in the trial group. The control group adopted the usual care measures, and the trial group applied the prevention program for noninvasive ventilation related facial pressure injuries. The incidence of pressure injury was compared between the two groups. Nurses in 7 wards were investigated before and after the intervention program to compare the changes of knowledge level.Results:In the control group, there were 354 males, 221 females, aged (77.13 ± 14.49) years old; in the trial group there were 392 males, 210 females, aged (75.60 ± 14.27) years old. The incidence of pressure injury in the trial group was lower than the control group, but showed no significant difference ( P>0.05). In the control group, 11 cases suffered pressure injury, including 5 cases in stage 2, 6 cases in stage 3 and above. There were 9 cases in the trial group, including 8 in stage 2 and 1 in stage 3 and above. The severity of pressure injury in the trial group was lower than that in the control group, and the difference was significant ( χ2 = 3.83, 4.11, both P<0.05). The scores of the nurse′pressure injury knowledge increased from (6.77 ± 1.53) points to (7.15 ± 1.47) points, with a significant difference ( t = -2.31, P<0.05). Conclusions:Management of the prevention of noninvasive mechanical ventilation related facial pressure injury through evidence-based practice can reduce its incidence, reduce its severity, and it is beneficial to improve the clinical nurses' prevention knowledge and clinical practice level of facial pressure injury related to non-invasive mechanical ventilation.
4.Research Progress and Thinking of Disease Cost Accounting Model Based on Parameter Allocation Method
Peiyong XIA ; Kui QIN ; Jia XUAN
Chinese Health Economics 2024;43(8):75-79
The relevant state departments issued a series of cost accounting systems,and put forward three disease cost accounting methods:project superposition method,service unit superposition method and parameter allocation method.Among them,parameter allocation method is not paid attention to in the theory and practice of hospital disease cost accounting.Based on the literature research,it clarifies the related concepts of disease cost accounting based on parameter allocation method,combs and summarizes the characteristics,accounting models and existing problems of disease cost accounting at home and abroad at present,and discusses the optimization and improvement path in order to promote the further improvement and popularization of this method and accelerate the extensive practical application of accounting results.
5.Research Progress and Thinking of Disease Cost Accounting Model Based on Parameter Allocation Method
Peiyong XIA ; Kui QIN ; Jia XUAN
Chinese Health Economics 2024;43(8):75-79
The relevant state departments issued a series of cost accounting systems,and put forward three disease cost accounting methods:project superposition method,service unit superposition method and parameter allocation method.Among them,parameter allocation method is not paid attention to in the theory and practice of hospital disease cost accounting.Based on the literature research,it clarifies the related concepts of disease cost accounting based on parameter allocation method,combs and summarizes the characteristics,accounting models and existing problems of disease cost accounting at home and abroad at present,and discusses the optimization and improvement path in order to promote the further improvement and popularization of this method and accelerate the extensive practical application of accounting results.
6.Research Progress and Thinking of Disease Cost Accounting Model Based on Parameter Allocation Method
Peiyong XIA ; Kui QIN ; Jia XUAN
Chinese Health Economics 2024;43(8):75-79
The relevant state departments issued a series of cost accounting systems,and put forward three disease cost accounting methods:project superposition method,service unit superposition method and parameter allocation method.Among them,parameter allocation method is not paid attention to in the theory and practice of hospital disease cost accounting.Based on the literature research,it clarifies the related concepts of disease cost accounting based on parameter allocation method,combs and summarizes the characteristics,accounting models and existing problems of disease cost accounting at home and abroad at present,and discusses the optimization and improvement path in order to promote the further improvement and popularization of this method and accelerate the extensive practical application of accounting results.
7.Research Progress and Thinking of Disease Cost Accounting Model Based on Parameter Allocation Method
Peiyong XIA ; Kui QIN ; Jia XUAN
Chinese Health Economics 2024;43(8):75-79
The relevant state departments issued a series of cost accounting systems,and put forward three disease cost accounting methods:project superposition method,service unit superposition method and parameter allocation method.Among them,parameter allocation method is not paid attention to in the theory and practice of hospital disease cost accounting.Based on the literature research,it clarifies the related concepts of disease cost accounting based on parameter allocation method,combs and summarizes the characteristics,accounting models and existing problems of disease cost accounting at home and abroad at present,and discusses the optimization and improvement path in order to promote the further improvement and popularization of this method and accelerate the extensive practical application of accounting results.
8.Research Progress and Thinking of Disease Cost Accounting Model Based on Parameter Allocation Method
Peiyong XIA ; Kui QIN ; Jia XUAN
Chinese Health Economics 2024;43(8):75-79
The relevant state departments issued a series of cost accounting systems,and put forward three disease cost accounting methods:project superposition method,service unit superposition method and parameter allocation method.Among them,parameter allocation method is not paid attention to in the theory and practice of hospital disease cost accounting.Based on the literature research,it clarifies the related concepts of disease cost accounting based on parameter allocation method,combs and summarizes the characteristics,accounting models and existing problems of disease cost accounting at home and abroad at present,and discusses the optimization and improvement path in order to promote the further improvement and popularization of this method and accelerate the extensive practical application of accounting results.
9.Research Progress and Thinking of Disease Cost Accounting Model Based on Parameter Allocation Method
Peiyong XIA ; Kui QIN ; Jia XUAN
Chinese Health Economics 2024;43(8):75-79
The relevant state departments issued a series of cost accounting systems,and put forward three disease cost accounting methods:project superposition method,service unit superposition method and parameter allocation method.Among them,parameter allocation method is not paid attention to in the theory and practice of hospital disease cost accounting.Based on the literature research,it clarifies the related concepts of disease cost accounting based on parameter allocation method,combs and summarizes the characteristics,accounting models and existing problems of disease cost accounting at home and abroad at present,and discusses the optimization and improvement path in order to promote the further improvement and popularization of this method and accelerate the extensive practical application of accounting results.
10.Research Progress and Thinking of Disease Cost Accounting Model Based on Parameter Allocation Method
Peiyong XIA ; Kui QIN ; Jia XUAN
Chinese Health Economics 2024;43(8):75-79
The relevant state departments issued a series of cost accounting systems,and put forward three disease cost accounting methods:project superposition method,service unit superposition method and parameter allocation method.Among them,parameter allocation method is not paid attention to in the theory and practice of hospital disease cost accounting.Based on the literature research,it clarifies the related concepts of disease cost accounting based on parameter allocation method,combs and summarizes the characteristics,accounting models and existing problems of disease cost accounting at home and abroad at present,and discusses the optimization and improvement path in order to promote the further improvement and popularization of this method and accelerate the extensive practical application of accounting results.

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