No abstract available.
Child* ; Humans ; Purpura, Thrombocytopenic, Idiopathic*

No abstract available.
Acute Kidney Injury* ; Child* ; Humans

No abstract available.
Hypoglycemia*

No abstract available.
Child* ; Hematuria* ; Humans

No abstract available.
Colorectal Neoplasms* ; Neoplasm Metastasis*

No abstract available.
Dislocations* ; Knee*

BACKGROUND: Primary gastric lymphoma is a rare neoplasm that represents 1~4% of all gastric malignancies. The optimal treatment of primary gastric lymphoma remains controversial. This study was designed to examine the prognostic significance of various clinicopathologic factors in patients with gastric lymphoma and to evaluate the role of surgery in the treatment of gastric lymphoma. METHODS: Retrospective study of 71 cases of primary gastric lymphoma which had been undergone laparotomy at the Department of Surgery, Seoul National University Hospital from Jan. 1982 to Dec. 1996 was performed. The authors reviewed clinicopathologic factors of patients and evaluated their prognostic significance. RESULTS: 1) The mean age of the patients was 50 years, and the most prevalent ages occurred in the 6th & the 7th decade. The ratio of males to females was 1.3:1. 2) The presenting symptoms and signs on admission were epigastric abdominal pain & discomfort, weight loss, anorexia, indigestion, and abdominal mass in decreasing order of frequency. 3) The diagnostic accuracy of the gastrofiberscopic biopsies was 67.1% preoperatively. 4) The most common pathologic type was diffuse histiocytic type (57.1%) in Rappaport classification, and diffuse large cell type (47.1%) in NCI Working formulation classification. 5) The distribution of stages according to modified TNM classification was 47.9% stage I, 36.6% stage II, 11.3% stage III, and 4.2% stage IV. 6) Overall, a potentially curative resection was performed in 92.9% of the cases. Treatment modalities included surgery (S), chemotherapy (CT), and radiotherapy (RT) in the following proportions: 33.8% only S, 53.5% S CT, 11.3% S RT, and 1.4% S CT RT. 7) The overall 5-year survival rate was 78.9%. The 5-year survival rates according to stage were 94.1% in stage I, 80.4% in stage II, 30.0% in stage III and 0% in stage IV.
Abdominal Pain ; Anorexia ; Biopsy ; Classification ; Drug Therapy ; Dyspepsia ; Female ; Humans ; Laparotomy ; Lymphoma ; Male ; Radiotherapy ; Retrospective Studies ; Seoul ; Survival Rate ; Weight Loss

PURPOSE: We purpose of this retrospective study is to evaluate the role of pancreaticoduadenectomy (PD) in gastric cancer which invades neighboring organs. MATERIALS AND METHODS: We analysed 28 patients with locally advanced gastric cancer which invaded to pancreas and/or duodenum who received surgical resection from Jan. 1989 to Dec. 1996. Patients were divided into two groups: Group A (n=12) who received PD and Group B (n=16) who received gastrectomy only. Indication of PD in group A is locally advanced gastric cancer which invaded to pancreas and/or duodenum but had no evidence of widespread nodal involvement, extended hepatic metastasis, or peritoneal dissemination. RESULTS: The operation time, amount of blood loss during operation, and postoperative hospital stay were greater in group A than in group B. Operative mortality was found in 1 case in group B but none in group A. Postoperative complications were similar in both groups. Four patients had liver metastases in both group during follow up period, whereas 2 and 4 patients had disseminated peritoneal seeding in group A and B, respectively. When survival rates were compared, Group A shows better survival than Group B (p= 0.043). CONCLUSION: These results suggest that PD is a rational and safe method for treatment of gastric cancer infiltrating into pancreatic head and/or duodenum.
Duodenum ; Follow-Up Studies ; Gastrectomy ; Head ; Humans ; Length of Stay ; Liver ; Mortality ; Neoplasm Metastasis ; Pancreas ; Pancreaticoduodenectomy* ; Postoperative Complications ; Retrospective Studies ; Stomach Neoplasms* ; Survival Rate

To further define the prognostic factors associated with long term survival of hepatocellular carcinoma, we retrospectively studied 371 patients with pathologically diagnosed hepatocellular carcinoma who underwent curative hepatic resection between 1991 and 1995. We included the 16 patients who underwent noncurative hepatic resection in calculating overall survival. The male to female ratio was 5.1 to 1 and their average age was 52.5 years. About 20 variables were subject to univariate and multivariate analysis and their survivals were calculated using the Kaplan-Meier method. 55.6% of (220 of 396) patients had liver cirrhosis and 73.2% of (290 of 396) patients were positive in HBsAg. Operative mortality and inhospital death rate were 1.5% and 0.8%, each and postoperative morbidity rate was 22.5%. The cumulative 1, 3 and 5 year survival rates including noncurative resected cases were 85.9%, 67.2% and 54.8%, respectively. The cumulative 1, 3 and 5 year survival rates of 371 curative resected cases were 87.3%, 68.7% and 56.4%, respectively. Disease free 1, 3, 5 year survival rates of 371 curative resected cases were 74.8%, 48.2% and 40.8%, respectively. The factors such as alpha- fetoprotein, Child's classification, prothrombin time, extent of liver resection, and number of tumor were statistically significant factors associated with cumulative survival.(p<0.05) And alpha-fetoprotein, total necrosis after TACE, viral hepatitis, and invasion of portal vein were significant factors associated with cumulative disease free survival. Only alpha-fetoprotein was associated significantly with cumulative survival and cumulative disease free survival. Length to the resection margin was not significantly associated with survival.
alpha-Fetoproteins ; Carcinoma, Hepatocellular* ; Classification ; Disease-Free Survival ; Female ; Fetal Proteins ; Hepatectomy ; Hepatitis ; Hepatitis B Surface Antigens ; Humans ; Liver ; Liver Cirrhosis ; Male ; Mortality ; Multivariate Analysis ; Necrosis ; Portal Vein ; Prothrombin Time ; Retrospective Studies ; Survival Rate

BACKGROUND: Severe liver disease is very often life threatening and dramatically diminishes the quality of life. An effective artificial liver support system should be capable of sustaining patients with severe liver disease, preparing patients for liver transplantation, and improving the survival of and the quality of life for patients for whom transplantation is not a therapeutic options. METHODS: As an elemental experiment for establishing a bioartificial liver system, rat hepatocytes were isolated in several hormone-supplemented culture media: 1) control group, 2) insulin supplemented media, 3) EGF supplemented media, 4) insulin EGF supplemented media. Using primarily the cultured and subcultured hepatocytes, we evaluated the hepatic cellular function in each media. RESULTS: The cellular viability was maintained as long as 10 days (average, 8.4 days). The hepatocytes in the group 4 media showed good results in ammonia degradation, ureogenesis, and albumin synthesis compared with those in the other groups. In the subculture, the hepatocyte functions had significantly declined. CONCLUSION: Insulin EGF supplemented culture media were superior to the others.
Ammonia ; Animals ; Culture Media ; Epidermal Growth Factor ; Hepatocytes ; Humans ; Insulin ; Liver Diseases ; Liver Transplantation ; Liver, Artificial ; Quality of Life ; Rats