A case of ectopic fascioliasis involving cecum and ascending colon was reported. This case was a 19-year old Korean female who had a history of postprandial aggravation of intermittent abdominal pain of 3 weeks duration. She was presented with an abdominal mass in the right upper quadrant, for which an operation(right hemicolectomy) was performed. Whole cecum and ascending colon showed multifocal tunnel-like necrotizing granulmas with central cavitations. Numerous Charcot-Leyden crystals were seen along tracts of the worm. The lesion was distributed throughout the entire thickness of the wall. Parasitological examination confirmed the worm found in the intestinal wall to be juvenile form of Fasciola species. Possibilities were discussed on the localization of the fluke and the mode of infection of present case.
parasitology-helminth-trematoda ; Fasciola sp. ; fascioliasis ; case report ; cecum ; colon ; granuloma

PURPOSE: A case-control study was conducted to evaluate the association between diet and breast cancer in Korean women. METHODS: The eligible subjects consisted of a series of histologically confirmed incident breast cancer patients (n= 1063) and non-cancer controls (n=1002) admitted to the departments of surgery at four teaching hospitals located in Seoul, Korea (Seoul National University Hospital, Borame Hospital, Samsung Medical Canter, and Asan medical Center) between 1995 and 2002, from whom blood samples were available. After excluding subjects with a previous history of cancer, hysterectomy or oophorectomy, the final study population consisted of 819 cases and 713 controls. The demographic characteristics and other information were collected by interviewed questionnaire. Dietary information obtained by trained interviewer using food frequency questionnaires. RESULTS: Women educated more than 12 years (OR=1.9, 95% CI: 1.4~2.7), with a higher body mass index (BMI) (OR= 1.4, 95% CI: 1.1~2.0) and a positive family history of breast cancer among the first degree relatives (OR=2.5, 95% CI: 1.3~4.3) were significant risk factors for breast cancer. The longer the exposure to estrogen during their lifetime, the higher the observed risk of breast cancer was (p for trend<0.001). The risk for breast cancer was increased with frequent consumption of cereals (OR=1.8, 95% CI: 1.8~2.5), potatoes (OR=1.8, 95% CI: 1.4~2.5), nuts and seeds (OR=1.9, 95% CI: 1.1~3.4), mushrooms (OR=1.5, 95% CI: 1.2~1.8), meats (OR=1.5, 95% CI: 1.2~1.9), eggs (OR=1.6, 95% CI: 1.1~2.3) and fish (OR=1.5, 95% CI: 1.2~1.9), whereas the risk decreased with higher intakes of green vegetables (OR=0.6, 95% CI: 0.4~1.0), fruits (OR=0.7, 95% CI: 0.6~0.9) and seaweeds (OR=0.7, 95% CI: 0.5~1.0). CONCLUSION: Certain diets (e.g., high fat, high carbohydrate, low vegetable or fruit intake, etc.) were significantly associated with the risk of breast cancer in Korea women, which were similar to the findings in Western countries.
Agaricales ; Body Mass Index ; Breast Neoplasms* ; Breast* ; Case-Control Studies* ; Edible Grain ; Chungcheongnam-do ; Diet* ; Eggs ; Estrogens ; Female ; Fruit ; Hospitals, Teaching ; Humans ; Hysterectomy ; Korea ; Meat ; Nuts ; Ovariectomy ; Ovum ; Surveys and Questionnaires ; Risk Factors ; Seoul ; Solanum tuberosum ; Vegetables