BACKGROUND:Zinc can improve bone reaction to titanium implants through regulation of osteoblast activity under the condition of osteoporosis. OBJECTIVE:To study the zinc ions effect on improving the stability of titanium implants under the condition of osteoporosis. METHODS:After removal of the ovary, 28 female Sprague-Dawley rats presented with osteoporosis symptoms for 12 weeks and then, they were randomly divided into two groups. Two kinds of titanium implants with (experimental group) or without zinc (control group) were inserted into the bilateral femoral metaphysis longitudinal y in the ovariectomized rats, separately. Three rats were selected from each group for double fluorescence labeling examination. Mineral apposition rate was calculated at postoperatively 6 weeks. Another four rats were selected from each group for histomorphometry analysis at postoperatively 12 weeks. Biomechanical test was in the remaining rats in the two groups to calculate the maximum push-out force and maximum shear force at 12 weeks postoperatively. RESULTS AND CONCLUSION:The double fluorescence labeling examination revealed that the mineral apposition rate was improved in the experimental group as compared with the control group (P<0.05). New bone formation occurred in the two groups. However, larger new bone amount, higher bone area ratio and bone-to-implant contact were detected in the experimental group (P<0.05 or P<0.01). The maximum push-out force and maximum shear force were also superior in the experimental group to the control group (P<0.05 or P<0.01). These findings indicate that zinc ions are capable of promoting bone formation and improving implant fixation in ovariectomized rats.

Objective: To study the effect of individualized treatment of prominent ears using mattress suture combined tubed cartilage method. Methods: A total of 21 patients (28 ears) with prominent ear deformity were retrospectively analyzed from January 2013 to December 2015. Horizontal mattress suture and tubed cartilage were used to correct the deformed ears. The patients were followed up for 6 months to 1 year (mean: 9 months). Results: Hematoma occurred in 3 cases after operation, but the wounds were healed after removal of hematoma. No infection, flap necrosis, cartilage absorption or deformation, or other complications occurred. 28 ears were corrected. The shape of the antihelix was smooth and the auriculocephalic angle and scapha-conchal angle were significantly reduced, compared with preoperative. No obvious scar hypertrophy was left on incision. Conclusions The method of horizontal mattress suture combined with tubed cartilage is simple to use for prominent ear, result in satisfactory and stable outcomes.

Objective To investigate the method and timing of reconstruction of anal stenosis induced by scar contracture after repair of defect in perineal region with paraumbilical flap using random pattern flap.Methods Ten patients who suffered anal stenosis induced by scar contracture after the first phase repair of defect of perineal region with paraumbilical flap were hospitalized from July 2009 to September 2015.Eight patients were with central type scar contracture of perineal region after healing of burn wound,and two patients were with lesion of perineal region which had been excised.In 6 to 8 weeks after the first phase surgery,two or three random pattern flaps were designed around the narrow anus in the survived paraumbilical flap.After thorough release of the narrow anus,the random pattern flaps were transferred to enlarge the anus.The tip of the lifted triangular flap was transferred to insert into the anal canal.The skin of anal canal or rectal mucosa was pulled out to be crossly-stitched with the flap.Results All the patients' narrow anuses were released and enlarged with one operation,and the diameters of the narrow anuses were enlarged to 2.0 to 3.0 cm.During follow-up of 6 to 36 months,the anal stenosis was totally released,and the symptom of difficult defecation was significantly improved;7 patients were excellent and 3 patients were good with evaluation of clinical criteria of anus function;no symptom of anal stenosis or rectal mucosal prolapse was observed any more.Conclusions In 6 to 8 weeks post repair of defect in perineal region with paraumbilical flap,designing of random pattern flap in the survived paraumbilical flap to enlarge and reconstruct the narrow anus has good therapeutic effects on anatomical narrow and difficult defecation.

Myogenous temporomandibular disorder(M-TMD)is one of the main subtypes of temporomandibular dis-order(TMD)and typically manifests as masticatory myofascial pain;the incidence of TMD has been increasing annually in recent years.Botulinum toxin type A(BTX-A)is a potent neurotoxin produced by Clostridium botulinum.BTX-A in-hibits the release of acetylcholine from the presynaptic membrane,thereby blocking neuromuscular junction signaling.The noncosmetic application of BTX-A in the oral and maxillofacial regions is a prominent research topic.In recent years,an increasing number of studies have focused on the application of BTX-A in the treatment of M-TMD.The re-sults of a literature review revealed that an appropriate dose(10-50 U unilaterally)of BTX-A administered in a single in-jection into the masticatory muscles can effectively treat myalgia over a period of 3-6 months.Common adverse effects,such as masticatory weakness and facial paralysis,are transient and can be avoided by standardized injection tech-niques.However,there is a lack of standardized guidelines for injection techniques in clinical practice.