No abstract available.
Animals ; Ascitic Fluid* ; Intestinal Obstruction* ; Lactic Acid* ; Rats*

No abstract available.
Adhesives* ; Intestinal Obstruction*

Canalith repositioning maneuver is effective to treat benign paroxysmal positional vertigo(BPPV). This case showed complicated form of the BPPV such as changes of canalolithiasis to cupulolithiasis, involvement of one canal to two canals and from unilateral to bilateral involvement during the reposition maneuver. This patient was diagnosed as left lateral canalolithiasis at first. After left barbecue maneuver, the type was changed to the right posterior cupulolithiasis. Semont maneuver was performed and then the type of BPPV was changed to combined type with right posterior canalolithiasis and left lateral canalolithiasis. We performed left barbecue maneuver and right Epley maneuver. Then the type of BPPV was changed to left lateral cupulolithiasis. After Brandt-Daroff maneuver and left barbecue maneuver, nystagmus and dizziness disappeared finally.
Dizziness ; Humans

No abstract available.
Amniotic Fluid* ; Animals ; Embryonic Structures* ; Female ; Humans* ; Mice*

Neurofibromatosis, or von Recklinghausen's disease, is a hereditary, harmartomatous disorder that primarilyinvolves neuroectoderm and mesoderm. The estimated incidence is 1 in 2,500 to 3,000 births. The clinical featuresare skin manifestations such as cafe-au-lait spots, skeletal manifestations primarily in volving vertebrae,central and peripheral nervous manifestations, and other associated abnormalities with increased risk ofmalignancy. The authors analysed the radiologic findings of 18 cases of patients with neurofibromatosis whovisited Pusan Kosin Medical Center and Taegu Dongsan Medical Center during the last five years. All were proven bysurgery, biopsy and other diagnostic criteria. The results obtained were as follows: 1. The male ot female ratiowas 11:7 and the age ranged from 11 months to 51 years. 2. All the cases fulfilled the diagnotic criteria of Croweand associates. 3. Bone manifestations were present in 44% of the cases. The other radiologic findings wereintrathoracic meningocele, bilateral acoustic neurinomas, mediastinal or chest wall mass shadows, and peripheralsoft tissue masses. 4. One of the soft tissue masses was proved to be malignant.
Biopsy ; Busan ; Cafe-au-Lait Spots ; Daegu ; Female ; Humans ; Incidence ; Male ; Meningocele ; Mesoderm ; Neural Plate ; Neurofibromatoses ; Neurofibromatosis 1 ; Neurofibromatosis 2 ; Parturition ; Skin Manifestations ; Thoracic Wall

BACKGROUND AND OBJECTIVES: It is known that various inflammatory mediators released from the eosinophils and mast cells play important roles in the pathogenesis of nasal polyp. Among those mediators, the arachidonic acid has particular importance as a precursor of other mediators. By assaying the tissue concentration of the6-keto-PGF(1alpha), leukotrienes (LTs), and hydroxyeicosatetraenoic acids (HETE) in the nasal polyp, we aimed to investigate the role of arachidonic acid metabolite in the pathogenesis of antrochoanal polyp and nasal polyp associated with chronic paranasal sinusitis. MATERIALS AND METHODS:Three turbinate tissues taken during the septoplasty were served as the control. The experimental group consisted of 3 antrochoanal polyps and 7 inflammatory polyps. The tissue level of the 6-keto-PGF(1alpha), LTC(4), LTD(4), LTE(4), 15-HETE, and 12-HETE were measured using high performance liquid chromatography. RESULTS: The level of 6-keto-PGF(1alpha), LTC4, 15-HETE, 12-HETE were significantly lower in antrochoanal polyp than in the control turbinate. In the inflammatory polyp, the levels of 6-keto-PGF(1alpha) and LTC(4) were lower than the control. However, in the inflammatory polyp, LTD(4) and LTE(4) were detectable, which were not detected in the control turbinate and antrochoanal polyp. CONCLUSION: The results of this study indicate that the decreased arachidonic acid metabolism may underlie the pathogenesis of the antrochoanal polyp. However, in the pathogenesis of inflammatory polyp, the increased production of LTD(4) and LTE(4) may have an important role.
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid ; Arachidonic Acid* ; Chromatography, Liquid ; Eosinophils ; Hydroxyeicosatetraenoic Acids ; Leukotriene C4 ; Leukotrienes ; Mast Cells ; Metabolism ; Nasal Polyps* ; Polyps* ; Sinusitis* ; Turbinates

Portal vein thrombosis (PVT) is a clinical situation that usually begins at the extrahepatic portal vein and sometimes extends into the intrahepatic portal vein, or distally to the superior mesenteric and splenic veins. The clinical presentation (asymptomatic to fatal bowel ischemia) and etiology (liver cirrhosis, systemic cause such as hypercoagulable state and myeloproliferative diseases, local cause such as acute appendicitis) is so diverse that the clinical decision making is sometimes very difficult. When the thrombus extends into the superior mesenteric vein, bowel ischemia and infarction should be anticipated and prevented cautiously with immediate initiation of anticoagulant therapy. The most troublesome chronic sequelae of the portal vein thrombosis is portal vein hypertension, which deteriorates patients' quality of life. The goal of treatment is to prevent ischemic bowel infarction and portal vein hypertension. Color Doppler sonography, computed tomography, and magnetic resonance imaging are convenient diagnostic tools to confirm PVT. The systemic thrombotic state or cause of infection must be determined through serologic studies. It is helpful to divide PVT patients into cirrhotic and non-cirrhotic, acute and chronic patients. In cases of non-cirrhotic acute PVT, rapid correction of the systemic and local cause of thrombosis and early initiation of anticoagulant therapy are considered the gold standard of treatment. In cases of cirrhotic and chronic PVT, the risk of bleeding and the efficiency of anticoagulation therapy should be measured and balanced for each patient. This article discusses the debated issue of the various treatment paradigms for PVT.
Decision Making ; Fibrosis ; Hemorrhage ; Humans ; Hypertension ; Infarction ; Ischemia ; Magnetic Resonance Imaging ; Mesenteric Veins ; Portal Vein ; Quality of Life ; Splenic Vein ; Thrombosis

BACKGROUND AND OBJECTIVES: There are caloric test, SCEP, DP in Step velocity and VOR asymmetry in SHA test as parameters for evaluation in unilateral peripheral vestibulopathy in parameter of vestibular function test. The aim of this study is to assess the correlation between these parameters and intensity of spontaneous nystagmus in vestibular neuritis. MATERIALS AND METHOD: We evaluated 75 patients who were diagnosed as vestibular neuritis with 3 degree spontaneous nystagmus at vestibular function test lab from January 2000 to July 2005 in Dankook university hospital. The correlations between direction and intensity of spontaneous nystagmus and monothermal caloric test, SCEP and DP in step velocity, VOR asymmetry (0.01, 0.04, 0.16 Hz) in SHA test were analysed. And correlations according to sex, age were also analysed. RESULTS: The correlation coefficient between intensity of spontaneous nystagmus and monothermal caloric test was 0.60. The correlation coefficient between intensity of spontaneous nystagmus and SCEP was 0.35. The correlation coefficient between intensity of spontaneous nystagmus and Tc DP was 0.36 and it showed no significant correlation. The correlation coefficient between intensity of spontaneous nystagmus and VOR asymmetry (0.01, 0.04, 0.16) was 0.57, 0.46, 0.51, respectively and there was higher correlation in man, age under 60. CONCLUSION: Intensity of spontaneous nystagmus showed close relations to monothermal caloric test, VOR asymmetry of SHA, Tc DP, SCEP DP in sequence. In addition, young male patients tends to be closely related to intensity of spontaneous nystagmus.
Caloric Tests ; Humans ; Male ; Vestibular Function Tests* ; Vestibular Neuronitis*

The exercise ECG gives a valuable indirect evidence of insufficient myocardial perfusion during stress, but it has been impossible with ECG data alone to localize the site or sites of partial or complete arterial occlusion. The coronary angiography has proved to be valvuable as a technique for identifying anatomical lesions. However, arteriography alone dose not provide evaluation of the underlying myocardium. The two tests are complementary, one supplying indirect physiologic data and the other providing anatomical licalization of obstruction. The author reviewd 58 patients out of 86 patients who performed treadmill test and coronary angiography at the cardiac laboratory of Yonsei University Severance Hospital from January, 1981 through December, 1983. The following results were obtained. 1) Among the 58 patients in this study, 33 had negative exercise test and 25 had positive test. 2) Among the 14 patients who ended exercise test due to chest pain,2patients had negative exercise test. Coronary angiography on all the 14 patients showed significalt coronary artery stenosis. 3) With this multigraded treadmill test, the sensitivity was 68.8% and spedccificity was 88.7%. 4) The appreance of ischemic change during the early stage of exercise, the deeper ST segment depression and the downsloping ST segment have the higest specificity as indicators of coronary artery disease. 5) Four patients showed ST segment elevation in the exercise ECG, and their coronary angiogram showed 1-vessel disease in 1 patientts, 2-vessel dosease in 2 and 3-vessel disease in 3. All of them had multiple stenosis or complete obstruction of the left anterior descending artery on coronary angiogram and ventricualar dyskinesia on the left ventriculogram.
Angiography ; Arteries ; Constriction, Pathologic ; Coronary Angiography ; Coronary Artery Disease* ; Coronary Stenosis ; Coronary Vessels* ; Depression ; Dyskinesias ; Electrocardiography ; Exercise Test* ; Humans ; Myocardium ; Perfusion ; Sensitivity and Specificity ; Thorax

BACKGROUND AND OBJECTIVES: The incidence of head trauma is increasing, with vertigo or dysequilibrium being the major disability when returning to normal activities. However, the lack of understanding of and appropriate diagnostic methods for dizziness inhibits effective treatment and rehabilitation. We identified the vestibular status of the head trauma patients complaining of dizziness. MATERIAL AND METHODS: We performed electronystagmography battery, rotational chair test and posturography on 79 patients who previously had had head trauma. The patients were then divided according to the five types of head trauma. RESULT: The results of the vestibular function tests(VFT) of the 79 patients were analyzed to give five distinct types: 23 central types(29.1%), 21 peripheral types(26.6%), 5 mixed types(6.3%), 14 non-localizing types(17.7%), and 16 normal types(20.3%). The most common VFT finding of the intracranial lesion group was the central type(70.6%), whereas that of the temporal bone fracture group was the peripheral type(45%). The combined lesion group did not show any single predominant VFT finding. The normal type(33.3%) was the most common fingding in the inapparent head trauma group. CONCLUSION: Although there is some tendency that the vestibular function status of head trauma patients corresponds to the clinical presentations, it did not coincide with many of the patients in this study. This means that the vestibular function tests should be thoroughly performed in head trauma patients complaining of dizziness, so that the patients may be evaluated more accurately and treated better.
Craniocerebral Trauma* ; Dizziness* ; Electronystagmography ; Head* ; Humans ; Incidence ; Rehabilitation ; Temporal Bone ; Vertigo ; Vestibular Function Tests*