1.A Case of Potter Syndrome with Bilateral Polycystic Kidneys.
Chun Hwa LEE ; Jung Hwan CHOI ; Yong CHOI ; Chong Ku YUN ; Yeon Lim SUH ; Je G CHI ; Son Moon SHIN
Journal of the Korean Pediatric Society 1987;30(11):1282-1286
No abstract available.
Polycystic Kidney Diseases*
2.Successful Sibling Cord Blood Stem Cell Transplantation for Relapsed Acute Mixed Lineage Leukemia.
Young Ho LEE ; Nam Cheol CHO ; Ku Hwa JE ; Hoon HAN ; Jin Yeong HAN ; Jae Seok KIM ; Hyo Jun KIM ; Bin CHO ; Hack Ki KIM
Korean Journal of Hematology 1999;34(3):471-476
No abstract available.
Cord Blood Stem Cell Transplantation*
;
Fetal Blood*
;
Humans
;
Leukemia*
;
Siblings*
3.Development of Tetracycline-regulated Adenovirus Expression Vector System.
Kyung Hwa SON ; Seung Hoon LEE ; Jong Sik KIM ; Jung Joo CHOI ; Je Ho LEE
Journal of Genetic Medicine 1999;3(1):33-36
Recombinant adenovirus vector systems with strong promoters have been used to achieve high level production of recombinant protein. However, this overexpression system cause some problems such as disturbance of cell physiology and increment of cellular toxicity. Here, we showed a tetracycline-regulated adenovirus expression vector system. Our results showed that the expression level of transgene(p-53) was high and easily regulated by tetracycline. In addition, the maximal gene expresion level of the tetracycline-controlled gene expression system was higher than that of the wild type CMV promoter system. Therefore, tetracycline-regulated adenoviral vector system could be applicable for regulatory high-level expression of toxic gene. Also, this system will be useful for functional studies and gene therapy.
Adenoviridae*
;
Cell Physiological Phenomena
;
Gene Expression
;
Genetic Therapy
;
Tetracycline
Result Analysis
Print
Save
E-mail