No abstract available.
Capnography* ; Humans

No abstract available.

Analgesia* ; Morphine* ; Narcotics

A 69-year-old man presented with annular lichen planus involving both forearms, hand dorsa, wrists, inner sides of the thighs, knees and ankles. He was treated initially with systemic corticosteroids and etretinate, but rernission and recurr ence of the skin lesions were observed. During the follow-up, we found erythrasma on all his toewebs and both soles. After administration of erythromycin for the treatment of erythrasma, lesions of the lichen planus rapidly improved. Five months later, some lesions of lihen planus and erythrasma had recurred. After administration of erythromycin, the lesions of lichen planus improved again. No recurrence was observed for the following 8 months. We suspect that eradication of the chronic focus of infection and the anti-inflammatory effect, of erythromycin may lead to supression of abnormal immunological reactions and resolution of lichen planus.
Acitretin ; Adrenal Cortex Hormones ; Aged ; Ankle ; Erythrasma ; Erythromycin* ; Etretinate ; Follow-Up Studies ; Forearm ; Hand ; Humans ; Knee ; Lichen Planus* ; Lichens* ; Recurrence ; Skin ; Thigh ; Wrist

PURPOSE: MIP-1 alpha, initially identified as a substance to promote inflammation, was recently discovered to also suppress proliferation of many kinds of cells. In this study, the influence of MIP-1 alpha on CD4+ Th cells to secrete cytokines (IL-10, IL-2, IFN-gamma) and to express CD25 molecules was investigated. METHODS: Peripheral blood mononuclear cells (PBMCs) were prepared from five normal volunteers and initially divided into 4 groups: IL-10, IL-2, IFN-gamma, and CD25. Each group was further divided into 4 subgroups according to the incubation with or without MIP-1 alpha and to the incubation for 30 minutes or 3 hours. Analysis was performed by flow cytometry. RESULTS: Incubation of CD4+ Th lymphocytes with MIP-1 alpha showed a tendency to increase Th1 cytokine (IL-2, IFN-gamma) secretion and to decrease Th2 cytokine (IL-10) release, but there was no significant difference between any of the experimental groups. Among the CD4+ Th lymphocyte groups cultured with MIP-1 alpha, the expression of CD25 was significantly lower in the 3-hour incubation group than in the 30-minute group (P=0.008). CONCLUSION: MIP-1 alpha may play a role in facilitating immune response by increasing Th1 and decreasing Th2 cytokine secretion from CD4+ Th cells, and also by decreasing the proportion of CD4+CD25+ Th cells in the peripheral blood. However, in vivo study is necessary to verify the function of MIP-1 alpha in the living body.
Cytokines ; Flow Cytometry ; Healthy Volunteers ; Inflammation ; Interleukin-10 ; Interleukin-2 ; Lymphocytes*

Anesthetists use halothane as a popular anesthetic agent, but after halothane anesthesia, hepatitis developed intermittently. However, it is not easy to prove halothane as a causative agent, because there are many factors causing hepatitis. We had a case of acute hepatitis developing after halothane anesthesia. Case: A 29-year-old male had an operation for split thickness skin graft on the right antetibial area under halothane anesthesia. Prior to operation, he was medicated Cefoxitin 1.0gm tid IV to control infection. On the postoperative 11th day, he developed high fever of 40.5 degrees C. Thereafter, skin rashes and jaundice followed. Liver function tests showed marked elevation of SGPT, SGOT, alkaline phosphatase, and eosinophillia. HBsAG(-), HBcAb(-), and HBeAg(-) were reported. There also was negative finding in HVA-IgM. He recovered gradually from the hepatitis and went home in good health on the 34th postoperative day. A possible cause or causes of the hepatitis in this case were considered to be the Cefoxitin adn/or the halothane.
Adult ; Alanine Transaminase ; Alkaline Phosphatase ; Anesthesia* ; Aspartate Aminotransferases ; Cefoxitin ; Exanthema ; Fever ; Halothane* ; Hepatitis* ; Humans ; Jaundice ; Liver Function Tests ; Male ; Skin ; Transplants

Great difficulty may be encountered in the differentiation of basal cell carcinoma from trichoepithelioma snd, in some cases, it may even be irnpossible. Immunohistochemical methods using peanut agglutinin(PNA) which is glycoprotein of non-immune origin selectively binding to galactose-N-acetyl-galactosa-mine are increasingly used in dermatopathology to improve the diagnosis and differential diagnosis. Using PNA, anti-PNA antibody, and peroxidase antiperoxi-dase(PAP) technique, normal skin specimens, basal cell carcinomas, trichoepitheliiomas, and a variety of different skin tumors were studied, and different PNA Ibinding sites between basal cell carcinomas and trichoepitheliomas were observed. The results were as follows : l. In normal skin, except the basement membrane, epidermis and hair follicle epithelium showed a cell membrane staining of PNA, which stained weakly in the Ibssal cell layer. Sebaceous glands revealed membranous and cytoplasmic staining of PNA, but sweat ducts and duct coi1s were mostly negative. 2. 34 of 36(94.4%) basal cell carcinoma sections demonstrated peritumorous PNA-positive bands, and none of 5 trichoepithelioma sections showed peritumorous PNA-binding. 3. Peritumorous PNA-positive bands were strongly positive in solid and keratotic basal cell carcinomas, but decreased or absent in the vicinity of the ulceration or the dense inflammatory infiltration. 4. None of the other skin tumors(squamous cell carcinoms, keratoscanthoma, Bowens disesse and actinic keratosis} showed a periturnorous PNA-positive band. Therefore, we believe that the PNA staining on paraffin-embedded sections using PAP technique can be a useful probe for the differentiation of basal cell carcinoma from trichoepithelioma.
Actins ; Basement Membrane ; Carcinoma, Basal Cell* ; Cell Membrane ; Cytoplasm ; Diagnosis ; Diagnosis, Differential ; Epidermis ; Epithelium ; Glycoproteins ; Hair Follicle ; Peanut Agglutinin* ; Peroxidase ; Sebaceous Glands ; Skin ; Sweat ; Ulcer

There are many article about hepatitis B antigen vaccination and protection against the hepatitis B viruses for medical people, however there are no article about surgical patients who had hepatitis B surface antigen. This study was performed to evaluate the eligibility for anesthesia and surgery of hepatitis B surface antigen positive patients by comparing pre-and post-operative liver function tests. Thirty hepatitis B surface antigen positive patients who were scheduled for surgery were selected for this study and another thirty hepatitis B surface antigen negative patients who were also scheduled for surgery were selected for the control group. AS result were concluded that the hepatitis B surface antigen positive patient who doesn't have active hepatitis is eligible for anesthesia and surgery.
Anesthesia* ; Hepatitis ; Hepatitis B ; Hepatitis B Surface Antigens ; Hepatitis B virus ; Humans ; Liver Function Tests ; Vaccination

No abstract available.
Cyclotrons*

From March 1987 to July 1989, six patients (five dadults and one child) with lung abscess (size, 5-13cm in diameter) were treated with percutaneous aspiration and drainage. In each case, the puncture was made where the wall of the abscess was in contact with the pleural surface. An 8 to 10 Fr catheter was inserted for drainage. Five of 6 had a dramatic clinical response within 24 hours of the drainage. Percutaneous drainage was successful with complete abscess resolution in four and partial resolution in one patient. No response was seen in the rest one. The duration of drainage ranged from 7 to 18 days (average, 15.5days) in successful cases. One case of the failure in drainage was due to persistent aspiration of the neurologically impaired patient. In one patient, the abscess resolved after drainage but recurred after inadvertent removal of the catheter 7 days after insertion. In two patients, concurrent pleural empyema was resolved completely by the drainage. Computed tomography provided anatomic details necessary for choosing the puncture site and avoiding a puncture of the lung parenchyma. Percutaneous catheter drainage is a safe and effective method for treating patients with lung abscess.
Abscess ; Catheters* ; Drainage* ; Empyema, Pleural ; Humans ; Lung Abscess* ; Lung* ; Methods ; Punctures