1.Surgical Removal of Retained Subfoveal Perfluorocarbon Liquid through a Therapeutic Macular Hole with Intravitreal PFCL Injection and Gas Tamponade.
Jae Min KIM ; Se Joon WOO ; Kyu Hyung PARK ; Hum CHUNG
Korean Journal of Ophthalmology 2013;27(5):392-395
We report two cases of surgical removal of a retained subfoveal perfluorocarbon liquid (PFCL) bubble through a therapeutic macular hole combined with intravitreal PFCL injection and gas tamponade. Two patients underwent pars plana vitrectomy with PFCL injection for rhegmatogenous retinal detachment. In both cases, a retained subfoveal PFCL bubble was noticed postoperatively by funduscopy and optical coherence tomography. Both patients underwent surgical removal of the subfoveal PFCL through a therapeutic macular hole and gas tamponade. The therapeutic macular holes were completely closed by gas tamponade and the procedure yielded a good visual outcome (best-corrected visual acuity of 20 / 40 in both cases). In one case, additional intravitreal PFCL injection onto the macula reduced the size of the therapeutic macular hole and preserved the retinal structures in the macula. Surgical removal of a retained subfoveal PFCL bubble through a therapeutic macular hole combined with intravitreal PFCL injection and gas tamponade provides an effective treatment option.
Aged
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Female
;
Fluorocarbons/*administration & dosage
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Follow-Up Studies
;
Fovea Centralis
;
Humans
;
Intravitreal Injections
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Retinal Perforations/diagnosis/physiopathology/*surgery
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Suction/*methods
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Tomography, Optical Coherence
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Visual Acuity
;
Vitrectomy/*methods
2.Gyrate Atrophy of the Choroid and Retina Diagnosed by Ornithine-delta-aminotransferase Gene Analysis: A Case Report.
Sang Jin KIM ; Dong Hui LIM ; Jae Hui KIM ; Se Woong KANG
Korean Journal of Ophthalmology 2013;27(5):388-391
A pair of 19-year-old female identical twins was referred to our hospital with progressive visual loss. They exhibited bilateral chorioretinal atrophy involving the midperiphery on fundoscopy and fluorescein angiography. Bilateral visual field constriction was noted on dynamic Goldmann perimetry, and a markedly impaired response was observed on both photopic and scotopic electroretinograms. Cystoid macular edema was identified in both eyes on optical coherence tomography. Plasma levels of ornithine were elevated. Based on these observations, the patients were diagnosed with gyrate atrophy of the choroid and retina. The clinical diagnosis was confirmed by mutation analysis of the ornithine-delta-aminotransferase (OAT) gene. Patients were treated with a pyridoxine supplement (300 mg/day) and an arginine-restricted diet to lower plasma levels of ornithine, which were successfully reduced without progression of chorioretinal atrophy for 15 months. Our report describes the first case of gyrate atrophy in the Korean population diagnosed by OAT gene analysis and treated with vitamin B6 dietary supplementation.
DNA/*analysis
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DNA Mutational Analysis
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Diagnosis, Differential
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Electroretinography
;
Female
;
Fluorescein Angiography
;
Fundus Oculi
;
Gyrate Atrophy/*diagnosis/enzymology/genetics
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Humans
;
*Mutation
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Ornithine-Oxo-Acid Transaminase/*genetics/metabolism
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Tomography, Optical Coherence
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Visual Acuity
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Young Adult
3.Choroidal Venous Pulsations at an Arterio-venous Crossing in Polypoidal Choroidal Vasculopathy.
Akiko OKUBO ; Munefumi SAMESHIMA ; Taiji SAKAMOTO
Korean Journal of Ophthalmology 2013;27(5):384-387
It has been reported that pulsations in abnormal vessels are observed on indocyanine green (ICG) angiography in half of patients with polypoidal choroidal vasculopathy (PCV), although the mechanism of the pulsation is unknown. In this study, we report a case of PCV showing venous pulsations at an arterio-venous (A-V) crossing, and discuss a possible mechanism of polypoidal vessel formation and pulsations in PCV. A 66-year-old female presented with a reddish-orange elevated lesion and serous retinal detachment in the macula of her left eye, and was diagnosed as PCV. She was treated with photodynamic therapy (PDT), and followed-up through routine examinations, including ICG angiography. ICG angiography at presentation showed a branching vascular network and choroidal venules with dye leakage (polypoidal vessels) in the left eye. Pulsations, supposedly of venous origin, were observed at an A-V crossing in the abnormal vessels. Within 3 months after PDT, the polypoidal vessel ceased to leak and the pulsations vanished. The reddish-orange lesion gradually decreased in size with complete disappearance of retinal detachment. This study suggests that an unusual compression at an A-V crossing may make a venule polypoidal, and fluctuations of blood flow and pressure in the venule may cause pulsatile movements of the vessel wall.
Aged
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Choroid/*blood supply
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Choroid Diseases/*diagnosis/physiopathology
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Diagnosis, Differential
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Female
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Fluorescein Angiography
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Fundus Oculi
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Humans
;
Retinal Vessels/*abnormalities/physiopathology
4.A Case of Susac Syndrome.
Han Joo CHO ; Chul Gu KIM ; Sung Won CHO ; Jong Woo KIM
Korean Journal of Ophthalmology 2013;27(5):381-383
The purpose of this article is to report on the first known Korean case of Susac syndrome. An 18-year-old female came to our clinic reporting blurred vision of the left eye for 2 days. She also complained of decreased hearing with tinnitus of the right ear and mild headache. She was previously healthy and had no remarkable medical history. Best-corrected visual acuity was 20 / 50 in the left eye and 20 / 20 in the right eye. An axiomatic triad of ocular, cochlear, and neurologic involvement was observed in the patient. Fluorescein angiography showed branched retinal arterial occlusions in the left eye. A sudden right sensorineural hearing loss was observed on audimetry. Magnetic resonance images showed a hyperintense lesion in the white matter around the corpus callosum. The patient was treated with high doses of systemic corticosteroids, and no neuropsychological sequelae were observed. This is the first case report of Susac syndrome in Korea. In cases of retinal arterial occlusion with hearing loss or neuropsychological symptoms, Susac syndrome should be suspected.
Adolescent
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Diagnosis, Differential
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Female
;
Fluorescein Angiography
;
Fundus Oculi
;
Hearing
;
Hearing Loss, Sensorineural/*diagnosis/physiopathology
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Humans
;
Magnetic Resonance Imaging
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Retinal Artery Occlusion/*diagnosis/physiopathology
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Susac Syndrome/*diagnosis/physiopathology
;
Visual Acuity
5.Bilateral Free Floating Vitreous Cysts with Posterior Embryotoxon.
Yajuvendra Singh RATHORE ; Ozhukil K RADHAKRISHNAN ; Nagbhushan CHOUGULE ; Abhay LUNE ; Renu MAGDUM ; Parikshit GOGATE
Korean Journal of Ophthalmology 2014;28(6):499-500
No abstract available.
Child
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Cornea/*abnormalities
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Cysts/*diagnosis
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Eye Abnormalities/*diagnosis
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Eye Diseases/*diagnosis
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Female
;
Humans
;
Visual Acuity/physiology
;
Vitreous Body/*pathology
6.A Case of Syphilitic Outer Retinitis Mimicking Acute Zonal Occult Outer Retinopathy.
Jeong Ah KIM ; Kyu Hyung PARK ; Se Joon WOO
Korean Journal of Ophthalmology 2014;28(6):497-499
No abstract available.
Anti-Bacterial Agents/therapeutic use
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Diagnosis, Differential
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Electroretinography
;
Eye Infections, Bacterial/*diagnosis/drug therapy
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Fluorescein Angiography
;
Humans
;
Male
;
Middle Aged
;
Penicillin G Benzathine/therapeutic use
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Retinitis/*diagnosis/drug therapy
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Scotoma/*diagnosis/drug therapy
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Syphilis/*diagnosis/drug therapy
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Syphilis Serodiagnosis
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Tomography, Optical Coherence
;
Visual Acuity/physiology
7.Orbital Dirofilariasis.
Se Hyun CHOI ; Namju KIM ; Jin Ho PAIK ; Jaeeun CHO ; Jong Yil CHAI
Korean Journal of Ophthalmology 2014;28(6):495-496
No abstract available.
Aged
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Animals
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Diagnosis, Differential
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Dirofilaria immitis/*isolation & purification
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Dirofilariasis/*diagnosis/parasitology/surgery
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Eye Infections, Parasitic/*diagnosis/parasitology/surgery
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Female
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Humans
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Ophthalmologic Surgical Procedures
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Orbital Diseases/*diagnosis/parasitology/surgery
9.Introduction of Lens-angle Reconstruction Surgery in Rabbit Eyes.
Min Hee KIM ; Ho Sik HWANG ; Kyoung Jin PARK ; Je Hyung HWANG ; Choun Ki JOO
Korean Journal of Ophthalmology 2014;28(6):486-492
PURPOSE: In this study, we examined the stability of the lens-angle supporter (LAS) for accommodation restoration by comparing intraocular lens (IOL) location, after-cataract and ciliary body damage after cataract surgery in rabbits. METHODS: Eight rabbits were divided into experimental and control groups of four rabbits each. Phacoemulsification and irrigation and aspiration were performed in all rabbits. This was followed by an LAS and IOL insertion in the four experimental rabbits. In the four control rabbits, only an IOL insertion was performed. Six months after the surgery, the location of the IOL, the conditions of the lens capsule and ciliary body were evaluated using a slitl-amp examination and Miyake-Apple view. RESULTS: For the experimental group, the ultrasound biomicroscope results showed normal LAS and IOL positioning in all four cases. According to the slitlamp examination and Miyake-Apple view, the IOL was positioned at the center, with less after-cataract and damage to the ciliary body. For the control group, ultrasound biomicroscope results indicated a higher IOL position than normal, as well as a single case of IOL decentering. According to the slit-lamp examination and Miyake-Apple view, the IOL was decentered with more severe after-cataract and ciliary body damage. CONCLUSIONS: The LAS has the potential to maintain a stable IOL position while producing less after-cataract when used in lens-angle reconstruction for correction of presbyopia. Moreover, LAS implantation incurs less damage to the ciliary body.
Accommodation, Ocular/physiology
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Animals
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Anterior Eye Segment
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Ciliary Body/injuries
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Disease Models, Animal
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Eye Injuries/*surgery
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Lens Capsule, Crystalline/*surgery
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*Lens Implantation, Intraocular
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Microscopy, Acoustic
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*Phacoemulsification
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Rabbits
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*Reconstructive Surgical Procedures
10.Congenital Aniridia: Long-term Clinical Course, Visual Outcome, and Prognostic Factors.
Ji Woong CHANG ; Jeong Hun KIM ; Seong Joon KIM ; Young Suk YU
Korean Journal of Ophthalmology 2014;28(6):479-485
PURPOSE: To describe the clinical course of congenital aniridia and to evaluate prognostic factors for visual outcome after long-term follow-up. METHODS: The medical records of 120 eyes from 60 patients with congenital aniridia were retrospectively reviewed. The prevalence and clinical course of ophthalmic characteristics, systemic disease, refractive errors, and visual acuity were assessed. Prognostic factors for final visual outcomes were analyzed. RESULTS: Aniridic keratopathy developed in 82 (69%) of 119 eyes. Macular hypoplasia was observed in 70 eyes of 35 patients (91%). Cataract was observed in 63 of 120 eyes (53%). Nystagmus was present in 41 patients (68% of 60 patients) at the initial visit but decreased in five patients (8% of 60 patients). Ocular hypertension was detected in 19 eyes (20% of 93 eyes), six (32% of 19 eyes) of which developed secondarily after cataract surgery. The mean changes in spherical equivalent and astigmatism during the follow-up period were -1.10 and 1.53 diopter, respectively. The mean final visual acuity was 1.028 logarithm of minimal angle of resolution. Nystagmus and ocular hypertension were identified as prognostic factors for poor visual outcome. CONCLUSIONS: Identification of nystagmus and ocular hypertension was important to predict final visual outcome. Based on the high rate of secondary ocular hypertension after cataract surgery, careful management is needed.
Adolescent
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Adult
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Aniridia/*diagnosis/physiopathology
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Cataract/diagnosis
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Child
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Child, Preschool
;
Corneal Diseases/diagnosis
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Eye Abnormalities/diagnosis
;
Eye Diseases/*diagnosis/physiopathology
;
Follow-Up Studies
;
Humans
;
Infant
;
Infant, Newborn
;
Nystagmus, Pathologic/diagnosis
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Ocular Hypertension/diagnosis
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Prognosis
;
Retina/abnormalities
;
Retrospective Studies
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Visual Acuity/*physiology
;
Young Adult