Alveolar soft part sarcoma (ASPS) is a rare and potentially aggressive soft tissue malignancy that primarily affects teenagers and young adults. It is generally associated with a high incidence of metastasis early in the disease course, with brain metastases occurring more frequently than in other high-grade sarcomas. ASPS most commonly arises in the extremities, particularly the lower limbs, while approximately one-fourth of cases occur in the head and neck region, with typical sites including the tongue and orbit, although involvement of the larynx is very rare. In this case report, we present a rare case of ASPS located in the larynx, accompanied by a review of the literature. This case emphasizes that ASPS should be considered in the differential diagnosis when evaluating solid and/or vascular laryngeal masses in the young population, and underscores the necessity of early surgical intervention.

Kimura’s disease is a rare, chronic inflammatory disorder that typically presents as painless head and neck masses in young Asian males, often accompanied by peripheral eosinophilia and elevated IgE levels. We report a case of recurrent Kimura’s disease involving the right parotid gland in a 35-year-old man, previously treated surgically. Due to tumor size (6 cm) and high risk of surgical complications, the patient underwent radiotherapy (30 Gy/15 fractions). Post-treatment imaging showed significant tumor reduction with no adverse effects or recurrence during 12 months of follow-up. While surgery remains the mainstay of treatment, recent studies suggest that radiotherapy or immunosuppressive therapy may be effective, especially in cases at high risk of recurrence. A recent meta-analysis identified tumor size ≥3 cm, prolonged disease duration (5 years), high eosinophil percentage (20%), and elevated IgE (10,000 IU/ml) as significant recurrence predictors. This case supports that radiotherapy may sere as a valuable treatment option when surgery in contraindicated or in high-risk recurrent cases.

Anaplastic thyroid carcinoma (ATC) is a rare and highly aggressive malignancy typically associated with dismal outcomes. Most patients present with advanced disease, often precluding curative resection. We report a case of intrathyroidal ATC incidentally identified in a 72-year-old male who underwent diagnostic lobectomy for a low-suspicion, predominantly cystic huge thyroid nodule. Final pathology revealed a completely resected, intrathyroidal ATC without extrathyroidal extension. Postoperative imaging showed no evidence of residual or metastatic disease. Based on multidisciplinary discussion, the patient underwent completion thyroidectomy and central neck dissection without adjuvant therapy. No residual malignancy was identified, and the patient remains recurrence-free at six months. This case highlights that early-stage intrathyroidal ATC may present without overt malignant features and can be curatively treated with complete surgical excision. Careful evaluation and multidisciplinary decision-making are essential in managing rapidly enlarging thyroid nodules with atypical features.

Pyogenic granulomas (PGs), also known as lobular capillary hemangiomas, are common reactive lesions that are non-neoplastic in nature. While they typically present as isolated lesions, they can rarely develop from preexisting port-wine stains (PWSs). PWS-associated PGs may occur spontaneously but are often linked to pregnancy or prior treatments such as laser therapy, intense pulsed light therapy, or radiotherapy. Here, we report a rare case of a PG arising from a PWS on the parietal scalp of a 27-year-old man with no history of trauma or prior treatment for his PWS. Given the potential for secondary lesion development in PWS, regular monitoring is essential, particularly in patients with associated risk factors.

An auricular pseudocyst is an uncommon, benign cystic lesion that frequently occurs in the auricles of middle-aged male patients, characterized histologically by an intracartilaginous, non-epithelial-lined cystic space. This report presents two cases of auricular pseudocysts successfully treated using deroofing procedures, with excellent long-term outcomes observed at 6-month and 5-year follow-up, respectively. Although various treatment modalities may be employed for these lesions, surgical deroofing is considered a conventional and reliable option that provides low recurrence rates and superior aesthetic outcomes.

Alveolar soft part sarcoma (ASPS) is a rare and potentially aggressive soft tissue malignancy that primarily affects teenagers and young adults. It is generally associated with a high incidence of metastasis early in the disease course, with brain metastases occurring more frequently than in other high-grade sarcomas. ASPS most commonly arises in the extremities, particularly the lower limbs, while approximately one-fourth of cases occur in the head and neck region, with typical sites including the tongue and orbit, although involvement of the larynx is very rare. In this case report, we present a rare case of ASPS located in the larynx, accompanied by a review of the literature. This case emphasizes that ASPS should be considered in the differential diagnosis when evaluating solid and/or vascular laryngeal masses in the young population, and underscores the necessity of early surgical intervention.

Kimura’s disease is a rare, chronic inflammatory disorder that typically presents as painless head and neck masses in young Asian males, often accompanied by peripheral eosinophilia and elevated IgE levels. We report a case of recurrent Kimura’s disease involving the right parotid gland in a 35-year-old man, previously treated surgically. Due to tumor size (6 cm) and high risk of surgical complications, the patient underwent radiotherapy (30 Gy/15 fractions). Post-treatment imaging showed significant tumor reduction with no adverse effects or recurrence during 12 months of follow-up. While surgery remains the mainstay of treatment, recent studies suggest that radiotherapy or immunosuppressive therapy may be effective, especially in cases at high risk of recurrence. A recent meta-analysis identified tumor size ≥3 cm, prolonged disease duration (5 years), high eosinophil percentage (20%), and elevated IgE (10,000 IU/ml) as significant recurrence predictors. This case supports that radiotherapy may sere as a valuable treatment option when surgery in contraindicated or in high-risk recurrent cases.

Anaplastic thyroid carcinoma (ATC) is a rare and highly aggressive malignancy typically associated with dismal outcomes. Most patients present with advanced disease, often precluding curative resection. We report a case of intrathyroidal ATC incidentally identified in a 72-year-old male who underwent diagnostic lobectomy for a low-suspicion, predominantly cystic huge thyroid nodule. Final pathology revealed a completely resected, intrathyroidal ATC without extrathyroidal extension. Postoperative imaging showed no evidence of residual or metastatic disease. Based on multidisciplinary discussion, the patient underwent completion thyroidectomy and central neck dissection without adjuvant therapy. No residual malignancy was identified, and the patient remains recurrence-free at six months. This case highlights that early-stage intrathyroidal ATC may present without overt malignant features and can be curatively treated with complete surgical excision. Careful evaluation and multidisciplinary decision-making are essential in managing rapidly enlarging thyroid nodules with atypical features.

Pyogenic granulomas (PGs), also known as lobular capillary hemangiomas, are common reactive lesions that are non-neoplastic in nature. While they typically present as isolated lesions, they can rarely develop from preexisting port-wine stains (PWSs). PWS-associated PGs may occur spontaneously but are often linked to pregnancy or prior treatments such as laser therapy, intense pulsed light therapy, or radiotherapy. Here, we report a rare case of a PG arising from a PWS on the parietal scalp of a 27-year-old man with no history of trauma or prior treatment for his PWS. Given the potential for secondary lesion development in PWS, regular monitoring is essential, particularly in patients with associated risk factors.

An auricular pseudocyst is an uncommon, benign cystic lesion that frequently occurs in the auricles of middle-aged male patients, characterized histologically by an intracartilaginous, non-epithelial-lined cystic space. This report presents two cases of auricular pseudocysts successfully treated using deroofing procedures, with excellent long-term outcomes observed at 6-month and 5-year follow-up, respectively. Although various treatment modalities may be employed for these lesions, surgical deroofing is considered a conventional and reliable option that provides low recurrence rates and superior aesthetic outcomes.