No abstract available.
Abdominal Pain* ; Melena*

No abstract available.

Melasma is characterized by chronic dark brown pigmentation on the face which is known to be little effective by remedies. It is still unkown the exact cause of the diaease, but pregnancy, oral contraceptives, sun-light, csometics, endocrinologic disturbances and malnutrition could be speculated as causative factors. According to our clinical experiences, some of the melasma patients were related with psychic and physical problems. The disease state of 400 cases with melasma was categorixed by our own designed questionaire, based on the dinical condition and history. 86 of 400 casea were analysed by Cornell Medical Index to elucidate the psycholagical and physiological problems
Contraceptives, Oral ; Cornell Medical Index ; Humans ; Malnutrition ; Melanosis* ; Pigmentation ; Pregnancy

No abstract available.
Amenorrhea* ; Cytogenetics* ; Female

No abstract available.
Amenorrhea* ; Cytogenetics* ; Female

No abstract available.
Ebstein Anomaly*

The pathogenetic mechanism of renal dysfunction in renal amyloidosis is poorly understood. To evaluate the morphologic parameters which are correlated with renal function in this disorder, we have examined renal biopsies from 14 patients with renal amyloidosis by morphometry. Of the 14 patients, 8 were male and 6 were female. They were between 41 and 70 years of age. The serum concentration of albumin and creatinine were 2.1+/-0.7 mg/dl and 1.1+/-0.5 mg/dl, respectively. The 24-hour excretion of urinary protein was 7.9+/-5.2 g. Creatinine clearance was 62+/-23 ml/min/1.73m2. The mean glomerular volume (MGV) was (2.2+/-1.3) 10(6) micrometer3. The surface density of peripheral glomerular basement membrane [Sv (PGBM/glom)] was 0.049+/-0.027 (micrometer3/micrometer3). Volume density of mesangium [Vv (mes/glom)] was 0.31+/-0.14 (micrometer3/micrometer3) and volume density of glomerular amyloid deposition [Vv (amyl/glom)] was 0.21+/-0.14 (micrometer3/micrometer3). The volume density of cortical interstitium [Vv (int/cortex)] was 0.14+/-0.09 (micrometer3/micrometer3). The serum creatinine concentration was significantly correlated with Vv (int/cortex) (r=+0.66, p<0.05). MGV was correlated with Vv (mes/glom) (r=+0.75, p<0.01) and Vv (amyl/glom) (r= +0.68, p<0.05) but showed negative correlation with Sv (PGBM/glom) (r=-0.79, p<0.01). Sv (PGBM/glom) showed negative correlation with Vv (mes/glom) (r=-0.77, p<0.01) and with Vv (amyl/glom) (r=-0.87, p<0.01). Positive correlation was observed between Vv (mes/glom) and Vv (amyl/glom) (r=+0.95, p<0.01). These results suggest that the decreased renal function in patients with amyloidosis is related to interstitial fibrosis rather than glomerular lesions. In addition, glomerular hypertrophy in these patients is related to amyloid deposition in the mesangium and peripheral glomerular basement membrane.
Amyloidosis* ; Biopsy ; Creatinine ; Female ; Fibrosis ; Glomerular Basement Membrane ; Humans ; Hypertrophy ; Male ; Plaque, Amyloid

No abstract available.
Environmental Monitoring* ; Health Promotion*

Primary tumor of the renal pelvis and ureter is relatively rare disease, but usually malignant. It's prognosis is dependent upon the early detection, accurate diagnosis, procedure for treatment, and tumor grade and stage. Therefore, urologist should endeavor after accurate diagnosis and definitive treatment. A clinical observation was done on the 11 patients with renal pelvic tumor and the 3 patients with ureteral tumor at the Department of Urology, Kyungpook National University Hospital during the period of 4 years from January, 1978 to December, 1981. The results were as follows: 1. There were 9 men and 5 women, giving a ratio of 1.8 to 1. The average age at presentation of the 14 patients was 51.4 years. 2. On excretory urogram, nonvisualization of the kidney was the most prevalent sign in 10 patients. Retrograde pyelogram was done in 11 patients in whom findings of IVP were not sufficient for diagnosis. Renal angi0graphy was done in 9 patients. 3. Urine cytology was positive in 2 of 14 patients. 4. Of the 13 patients treated, 12 were proved to have transitional cell carcinoma, and 1 was leiomyoma. In 3 of the 11 patients with renal pelvic tumor, Concomitant ureteral tumor was present at diagnosis. And in 2 of the 11 patients with renal pelvic tumor developed subsequent urothelial tumors in the ureter and/or bladder after simple nephrectomy. 5. Nephroureterectomy including resection of a bladder cuff was done in 11 patients, and in 2 of these was also performed lymphadenectomy. Simple nephrectomy was done in 2 patients with renal pelvic tumor under the misdiagnosis of renaltuberculosis. 6. Postoperative complications developed in 3 cases, wound infection, pneumothorax, and death, in each case.
Carcinoma, Transitional Cell ; Diagnosis ; Diagnostic Errors ; Female ; Gyeongsangbuk-do ; Humans ; Kidney ; Kidney Pelvis* ; Leiomyoma ; Lymph Node Excision ; Male ; Nephrectomy ; Pneumothorax ; Postoperative Complications ; Prognosis ; Rare Diseases ; Ureter* ; Urinary Bladder ; Urology ; Wound Infection

In order to evaluate the health hazard due to organ orphosphorus insecticides, we measured the blood cholinesterase activity and urinary para-nitrophenol among 56 exposed subjects. They are orchard workers, rice plant workers and smithion factory workers. The clinical symptoms were also checked by physicians. We also measured the blood cholinesterase activity and urinary para-nitrophenol excretion of 20 urban people and 15 rural people who had never been exposed to organophosphorus insecticides in order to compare them according to age, sex and geographical differences. And these results were also compared with those of exposed groups. The results obtained were as follows. 1. The normal plasma cholinesterase activity and cell cholinesterase activity were 0.861+/-0.148 delta pH/hr and 0.822+/-0.154 delta pH/hr. And normal para-nitrophenol in urine was 1.21+/-0.52 mg/liter. 2. No significant difference was existed in blood cholinesterase activities and urinary para-nitrophenol excretion according to sex, age and geographical difference. 3. The plasma cholinesterase activity and cell cholinesterase activity of orchard workers, rice plant workers and smithion factory workers were 0.682+/-0.189 delta pH/hr, 0.775+/-0.160 delta pH/hr, 0.754+/-0.123 delta pH/hr and 0.691+/-0.082 delta pH/hr, 0.756+/-0.117delta pH/hr. And significant decreases in blood cholinesterase activities were existed among orchard workers and smithion factory workers compared with control group. 4. The urinary para-nitrophenol excretions of orchard workers, rice plant workers and smithion factory workers were 1.33+/-0.66 mg/liter, 1.19+/-0.88mg/liter and 1.37+/-0.67mg/liter and there were no significant difference between exposed groups and control group. 5. The clinical symptoms complained during and after organophosphorus insecticides exposure were frequently ranked by headache (67.7%) and vertigo (64.5%) and muscular ataxia and weakness (51.6%).
Ataxia ; Cholinesterases* ; Headache ; Insecticides* ; Plants ; Plasma ; Vertigo