1.Three-year experience of primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction in a hospital without on-site cardiac surgery.
Sea Hing ONG ; Victor Y T LIM ; Boon Cheng CHANG ; Jayaram LINGAMANAICKER ; Chong Hiok TAN ; Yew Seong GOH ; Kok Soon TAN
Annals of the Academy of Medicine, Singapore 2009;38(12):1085-1089
INTRODUCTIONPrimary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) in hospitals without on-site cardiac surgery capability, despite receiving only a class IIb recommendation in the ACC/AHA practice guidelines, can be performed effectively and safely. We reviewed the fi rst 3 years of our experience.
MATERIALS AND METHODSThis is a retrospective single centre review of all patients receiving primary PCI for STEMI between 2003 and 2005. Demographic, procedural and outcome data were analysed.
RESULTSThere were 259 patients who underwent primary PCI. The mean age was 55.3 +/- 12.3 years. Median door-to-balloon time was 97.5 minutes and 45.2% and 52.9% had anterior and inferior STEMI, respectively. The majority of patients presented with Killip class I (87.6%); however, 5.8% were in Killip class IV. Single vessel disease was found in 47.1%. Angiographic PCI success (defined as residual stenosis <50% with TIMI 3 fl ow) was achieved in 89.1%. Usage of stents, distal protection and aspiration devices were 97.2%, 27.8% and 34.1 %, respectively; 9.3% required intra-aortic balloon pump insertion. No patients required transfer for emergency coronary bypass surgery as a result of PCI complications. Post-PCI ST resolution >50% was achieved in 80.6%. The mean post-infarct left ventricular ejection fraction was 44.1%. In-hospital, 30-day, 6-month and 1-year mortality rates were 2%, 2.8%, 4.0% and 4.8%, respectively. Clinically driven target lesion revascularisation rate was 2.8% at 1 year.
CONCLUSIONSOur results are comparable to those from on-site surgical centres. This supports the feasibility and safety of primary PCI in cardiac centres without on-site cardiac surgery.
Angioplasty, Balloon, Coronary ; Female ; Hospitals ; Humans ; Male ; Middle Aged ; Myocardial Infarction ; therapy ; Retrospective Studies ; Time Factors
2.A review of aortic disease research in Malaysia
Gerald Tan Jack Soon ; Paul Khoo Li Zhi ; Sailesh Mohana Krishnan ; Chan Kok Meng
The Medical Journal of Malaysia 2019;74(1):67-78
Aortic disease includes conditions such as
chronic aortic aneurysms, acute aortic syndromes and
congenital aortic abnormalities, amongst others. This paper
reviews all research on aortic disease performed in Malaysia
and published between 2000-2016.