1.Results of gastric mass survey in Tsuchiura Kyodo Hospital.
Katsuhiro Sanada ; Mamoru Takeshi ; Koji Koike ; Kazuo Hirose ; Koichi Matsuda ; Yoshio Ishida ; Yoji Nakazawa ; Masahiro Tsubaki ; Tomoyuki Suzuki ; Kazushi Seki ; Susumu Hiranuma ; Koichi Shibata ; Kohei Okamoto ; Shin Tonouchi
Journal of the Japanese Association of Rural Medicine 1985;33(5):907-912
We began gastric mass survey at our hospital in May, 1980. During 3 years and 8 months since then, (May, 1980-December, 1983) we performed screening examinations to 16, 341 people by indirect radiography, and checked 2, 824 cases (17.3%) for thorough examination. Among these cases, 2, 083 (73.8%) received endoscopic examination actually, and 55 cases of gastric cancer were discovered. The discovery rate of gastric cancer was 0.336 per cent.
35 cases of these 55 gastric cancer were operated in the surgical department of our hospital. 34 cases were resected (rate of resection was 97.1%) and 33 cases were resected curatively (rate of curative resection was 94.3%). These results were better than that of gastric cancer cases from out-patient clinic of the same period. The results of cases from out-patient clinic of our hospital were: total number of cases 321, resected cases 254 (79.1%), curative resection 189 cases (58.9%), respectively.
2.Role of IL-23 and Th17 Cells in Airway Inflammation in Asthma.
Hiroshi NAKAJIMA ; Koichi HIROSE
Immune Network 2010;10(1):1-4
Asthma is characterized by chronic airway inflammation with intense eosinophil and lymphocyte infiltration, mucus hyperproduction, and airway hyperresponsiveness. Accumulating evidence indicates that antigen-specific Th2 cells and their cytokines such as IL-4, IL-5, and IL-13 orchestrate these pathognomonic features of asthma. In addition, we and others have recently shown that IL-17-producing CD4+ T cells (Th17 cells) and IL-23, an IL-12-related cytokine that is essential for survival and functional maturation of Th17 cells, are involved in antigen-induced airway inflammation. In this review, our current understanding of the roles of IL-23 and Th17 cells in the pathogenesis of allergic airway inflammation will be summarized.
Asthma
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Cytokines
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Eosinophils
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Inflammation
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Interleukin-13
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Interleukin-17
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Interleukin-23
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Interleukin-4
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Interleukin-5
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Lymphocytes
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Mucus
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Neutrophils
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T-Lymphocytes
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Th17 Cells
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Th2 Cells