A 35-year-old woman, previously treated for systemic metastases from retroperitoneal yolk sac tumor, presented with progressive painful paraparesis. Preoperative images showed severe cord compression by the metastatic infiltration of the lumbar vertebrae and epidural mass as well as a huge retroperitoneal mass. While performing unremarkable surgery in prone position, the patient abruptly fell into hypoxic insults and circulatory arrest. Intraoperative pulmonary tumor embolism was deemed a cause of death. When planning operative procedure for this dangerous malignancy, scrupulous manipulation is mandated and the possibility of fatal pulmonary tumor embolism should also be addressed and fully discussed preoperatively.
Adult* ; Cause of Death ; Endodermal Sinus Tumor* ; Female ; Humans ; Lumbar Vertebrae ; Neoplasm Metastasis ; Neoplastic Cells, Circulating* ; Paraparesis ; Prone Position ; Spinal Cord Compression* ; Spinal Cord* ; Surgical Procedures, Operative ; Yolk Sac*

OBJECTIVE: Prognostic factors of metastatic brain tumors have been widely reported and their operative indications also have been extended gradually even to the poor grade patients. Authors intended to analyze the causative factors for the clinical outcome of metastatic brain tumors, especially with relevant to the poor prognosis by one year follow-up evaluation. PATIENTS AND METHODS: The authors retrospectively studied the clinical characteristics of 46 cases(35 patients) with metastatic brain tumors among 466 cases(437 patients) which were operated on due to the brain tumor, during the period between January 1994 to June 1999. Statistical analysis was performed by using SPSS 8.0(r). A p-value of less than 0.05 was considered clinically significant. RESULT: Among the variable clinical factors in patients with metastatic brain tumors, Karnofsky Performance Scale (KPS) score of less than 70(16 patients), uncontrolled primary tumor(8 patients), and surgical resection without further adjuvant therapy(9 patients) showed statistically significant poor prognosis; p value of 0.002, 0.032, and 0.001, respectively. Other tested variables, such as old age(greater than 65 years; 10 patients), gender(male; 20 patients), type of primary cancer(primary undefined; 6 patients, lung cancer; 15 patients), location(infratentorial; 9 patients, sellar; 5 patients), number of lesion(multiple; 12 patients), and number of operation(multiple craniotomy; 7 patients) were not related to the poor prognosis. CONCLUSIONS: The most common primary site of distant metastasis was lung. The poorer prognosis was highly correlated with various factors including low KPS score(<70), no postoperative adjuvant therapy, and uncontrolled primary tumors.
Brain Neoplasms* ; Brain* ; Craniotomy ; Follow-Up Studies* ; Humans ; Lung ; Lung Neoplasms ; Neoplasm Metastasis ; Prognosis* ; Retrospective Studies

A technique and clinical experiences of minimally invasive anterior lumbar interbody fusion ( mini-ALIF ) are reported. Despite its biomechanical advantages and high fusion rate, conventional ALIF needs a long skin incision and extensive dissection. Endoscopic approaches for ALIF seem to be associated with considerable technical difficulties, long operation time, and high complication rate even in collaboration with a laparoscopic surgeon. Mini-ALIF involves a standardized minimally invasive microsurgical retroperitoneal approach for L2-3 to L4-5, and transperitoneal approach for L5-S1. Mini-ALIF can be done through minimal skin incision(4-5cm) and blunt muscle dissection without abdominal muscle cutting. The surgical indications are degenerative disc diseases, disc herniations, degenerative spondylolisthesis, and iatrogenic postoperative instability including postoperative pseudarthrosis. Lumbar artificial disc replacement is a new indication to this technoque. Mini-ALIF provided sufficient operation space for lumbar interbody fusion. Consequently, operation time, bleeding, and postoperative morbidity of ALIF could be reduced.
Abdominal Muscles ; Bleeding Time ; Cooperative Behavior ; Microsurgery ; Muscles ; Pseudarthrosis ; Skin ; Spinal Fusion ; Spine ; Spondylolisthesis ; Total Disc Replacement

OBJECTIVE: This investigation was conducted to evaluate a new, safe entry point for the C2 pedicle screw, determined using the anatomical landmarks of the C2 lateral mass, the lamina, and the isthmus of the pars interarticularis. METHODS: Fifteen patients underwent bilateral C1 lateral mass-C2 pedicle screw fixation, combined with posterior wiring. The C2 pedicle screw was inserted at the entry point determined using the following method : 4 mm lateral to and 4 mm inferior to the transitional point (from the superior end line of the lamina to the isthmus of the pars interarticularis). After a small hole was made with a high-speed drill, the taper was inserted with a 30 degree convergence in the cephalad direction. Other surgical procedures were performed according to Harm's description. Preoperatively, careful evaluation was performed with a cervical X-ray for C1-C2 alignment, magnetic resonance imaging for spinal cord and ligamentous structures, and a contrast-enhanced 3-dimensional computed tomogram (3-D CT) for bony anatomy and the course of the vertebral artery. A 3-D CT was checked postoperatively to evaluate screw placement. RESULTS: Bone fusion was achieved in all 15 patients (100%) without screw violation into the spinal canal, vertebral artery injury, or hardware failure. Occipital neuralgia developed in one patient, but this subsided after a C2 ganglion block. CONCLUSION: C2 transpedicular screw fixation can be easily and safely performed using the entry point of the present study. However, careful preoperative radiographic evaluation, regardless of methods, is mandatory.
Ganglion Cysts ; Humans ; Ligaments ; Magnetic Resonance Imaging ; Mandrillus ; Neuralgia ; Spinal Canal ; Spinal Cord ; Vertebral Artery

To describe the detailed microsurgical anatomy of the clinoid(C5)segment of the internal carotid artery(ICA) and surrounding structures and clarify the anatomical relationships of this region emphasizing their clinical relevance, authors examined in 70 specimens from 35 formalin fixed cadaveric heads. Removal of the anterior clinoid process exposes the C5 segment of the ICA which is encircled by the thin inner dural layer of the cavernous sinus wall. Opening this membrane enables entrance into a narrow space that communicates with cavernous sinus through the proximal dural ring. Unlike the dura of the distal dural ring that is tightly attached to the ICA, the proximal dural ring is always incompetent. The C5 segment of the ICA has been considered by the majority of authors to be extracavernous. This understanding developed because most investigators overlooked the thin inner dural layer encircling the clinoid ICA. The narrow space between the inner dural layer and the ICA communicates with cavernous sinus through an incompetent proximal dural ring. Therefore, the clinoid ICA should be considered to be the most rostral portion of the cavernous (C4)segment of the ICA. The proximal dural ring is a surgical landmark rather than a true dural ring.
Cadaver ; Carotid Artery, Internal* ; Cavernous Sinus ; Formaldehyde ; Head ; Humans ; Membranes ; Research Personnel

OBJECTIVE: Various lesions including tumors occupying in the presellar and suprasellar regions have been traditionally removed by the transcranial approach. The new modified transsphenoidal approaches(TSAs) have been proposed to avoid the craniotomy and to get better surgical view. MATERIALS AND PATIENTS: The sellar floor and presellar anterior cranial fossa were removed through the sublabial transseptal transsphenoidal technique in the "transsphenoidal supradiaphragmatic intradural approach". One tuberculum sella meningioma and a suprasellar Rathke's cleft cyst confined to the pituitary stalk were removed via this approach. RESULTS: The dissection of the anterior intercavernous sinus, diaphragma sella, and arachnoid membrane allowed a wide surgical field of pre- and suprasellar areas and facilitated a safe removal of lesions without significant surgical complications in our cases. CONCLUSION: From the authors' limited experience, the advantages of this technique are as follows: 1) it can be easily applicable through a minor modification of the standard TSA, 2) excellent anatomical exposure of the structures located in the supradiaphragmatic suprasellar cistern, and 3) might be suitable to remove small lesions located in the presellar and adjacent to the pituitary stalk region.
Arachnoid ; Cranial Fossa, Anterior ; Craniotomy ; Humans ; Membranes ; Meningioma ; Pituitary Gland

OBJECTIVE: The safety and efficacy of various fusion substitutes in pyogenic osteomyelitis has not been investigated. We evaluated and compared the cadaveric allograft and titanium cages used to reconstruct, maintain alignment and achieve fusion in the management of pyogenic spinal infection. METHODS: There were 33 patients with pyogenic osteomyelitis underwent fusion in this study. Fifteen of the 33 patients were operated on by fusion with allografts (cadaveric patella bones) and 18 of those were operated with titanium mesh cages filled with autologous cancellous iliac bone. After the affected disc and vertebral body resection with pus drainage, cadaveric allograft or titanium cages were inserted into the resected space. Posterior transpedicular screw fixation and rod compression in resected space, where cadaveric allograft or titanium cages were inserted, was performed to prevent the malposition in all patients except in 1 case. Recurrent infection was identified by serial erythrocyte sedimentation rate and cross reactive protein follow-up. Osseous union and recurred infection available at a minimum of 2 years following operation was identified. The amount of kyphosis correction and the subsidence were measured radiographically. RESULTS: Spinal fusion was achieved in 29 of 33 patients. In the cadaveric allograft group, 93.3% of patient (14 of 15) showed the osseous union while 83.3% of patient (15 of 18) in the titanium cage group showed union. Subsidence was noted in 12 of the patients. Twelve patients (36.3%) showed unsettling amounts of subsidence postoperatively whereas 46.6% of patients in the cadaveric allograft group and 37.7% of patients in the titanium cage group showed similar subsidence, respectively. There were statistical difference in the fusion rate (p=0.397) and subsidence rate (p=0.276) between the two groups. There was significant statistical difference in the postoperative improvement of segmental kyphosis between the two groups (p=0.022), that is the improvement in sagittal alignment was greater in the titanium cage group than in the cadaveric allograft group. There was no case of recurred infection. CONCLUSION: The cadaveric allograft and titanium cages are effective and safe in restoring and maintaining sagittal plane alignment without increased incidence in infection recurrence in pyogenic osteomyelitis. The postoperative improvement of segmental kyphosis was better in the cage group.
Blood Sedimentation ; Cadaver ; Drainage ; Follow-Up Studies ; Humans ; Incidence ; Kyphosis ; Osteomyelitis ; Patella ; Recurrence ; Spinal Fusion ; Suppuration ; Titanium ; Transplantation, Homologous

No abstract available.
Arteries* ; Intracranial Aneurysm*

No abstract available.
Aneurysm*

No abstract available.
Aneurysm*