1.Situation of tuberculosis in Viet Nam from an IS 6110 fingerprint analysis of Mycobacterium tuberculosis strains isolated from patients
Journal of Preventive Medicine 1998;8(4):5-13
An IS 6110 fingerprint analysis of 168 Mycobacterium tuberculosis strains isolated from Vietnamese patients has been performed; 67 strains are isolated in the North (N strains), strains isolated in the South comprise 66 strains from tuberculosis patients without AIDS (S strains) and 35 strains from tuberculosis patients with AIDS (A strains). The number of IS 6110 copies per strain varies from 1 to 22 copies. The population of N strains are different from the population of the overall South strains where there was a high prevalence of strains with more than 15 IS copies. That regional difference between the Vietnamese strains was clearly shown by the fingerprint patterns of strains with more than 6 IS. The populations S strains and the A strains have similar fingerprint patterns and 80% of the South strains belong to one big family. In the contrary, a high polymorphism was seen among the N strains
Tuberculosis
;
Mycobacterium
;
Sprains and Strains
;
epedemiology
2.Some opinions of coagulation in artherosclerosis.
Journal of Vietnamese Medicine 2001;267(12):40-43
A hemotasis study of 93 cases of arteriosclerosis in Vietnames patients showed: -A hemorrhage tendency of extrinsic pathway abnormalities. -A thrombotic tendency by increasing fibrinogen, factor VII,factor VIII. The C reactive protein (CRP), specific for inflammatory process can be used for evaluation of physiopathology and plaque evolution.
Arteriosclerosis
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Blood Coagulation
3.Study on the colony of lymphocyte B, T in the treatment of the bronchial asthma combining with the traditional Qi training.
Journal of Practical Medicine 2002;435(11):51-54
A study on the combination of treatment and traditional Qi training for 65 patients with bronchial asthma in the National hospital of traditional medicine in 1992 has shown that the number of colony of the lymphocyte B,T, T-CD 8 after Qi training were a statistical insignificant different from this before Qi training (p= 0.05) the number of colony of the lymphocyte T- CD4 were reduced a statistical significant from this before QI training (p= 0.05). This indicated the correlation with the extend of obstruction of ventilation. The rate of T- CD4 and T-CD8 after Qi training was a statistical significant different from this before Qi training (p= 0.05).
Asthma
;
therapy
;
therapeutics
4.Clinical changes in the treatment of asthma combining with traditional Qi training and vital maintenance
Journal of Practical Medicine 2002;435(11):2-5
65 patients were divided into two groups: control group (31 patients): drug therapy without Qi training and group test (34 patients): drug therapy combined with traditional Qui training and vital maintenance. The results have shown that the frequency of asthma attacks and times of drug using after Qi training and vital maintenance were reduced comparing with these before Qi training and vital maintenance.
Asthma
;
therapy
;
diagnosis
;
therapeutics
5.Research on some effects and acute toxicity of Kim Ngan Hoa
Journal of Medical Research 2002;18(2):40-46
There different extract solutions of Kim Ngan Hoa were used in this study. The experimental results showed that: Kim Ngan Hoa has analgesic effect on two experimental models, hotplate and writing test on mice. Beside of analgesic effect, it has significantly acute antiinflammatory effect on rats. The effects of flavonoid and the alcoholic extract are potent than the effects of the water extract. Three extract solutions from Kim Ngan Hoa have also inhibitory effect in vitro the developing of three bacteria: Staphylococcus aureus, E. coli and Pseudomonas aeruginosa. Three preparations from Kim Ngan Hoa have very low acute toxicity
Acute Toxicity Tests
;
Research
;
Pharmaceutical Preparations
;
Toxicity
6.Evaluation of initial antibiotic regimens for nosocomial pneumonia in the elders
Journal of Vietnamese Medicine 2005;314(9):22-27
Nosocomial pneumonia is a leading type of respiratory infection among hospital-acquired infections. Despite the introductions of new antibiotics, nosocomial pneumonia is associated with high morbidity and mortality. Among 80 patients aged more than 60 years old with nosocomial pneumonia, 17 patients (21.3%) received initial adequate therapies, 63 patients (78.7%) received initial inadequate therapies. Nosocomial pneumonia is often difficult to treat because of multi-resistant bacteria. Initially adequate antibiotic regimens are major prognostic factor for patients with nosocomial pneumonia. 3rd generation cephalosporines and fluoroquinolones aren’t effective. Imipenem, Timentin, Tazoncin, Cepfepim plus Amikacin and Vancomicin (if suspected bacterium is S. aureus) can be initial effective antibiotics
pneumonia
7.Antibiotic resistance of bacteria caused nosocomial pneumonia in adults at Thong Nhat hospital from Jan 2004 to Jun 2005
Journal of Vietnamese Medicine 2005;313(8):15-23
An prospective study was carried out on 101 patients over 60 years of age with pneumonia at Thong Nhat hospital from January 2004 to June 2005. The result showed that: 87.1% of pneumonia caused by negative-gram aerobes, among which P.aeruginosa accounted for 55.4%, K. pneumonia 55.4%, Acinetobacter 14.9%. 15.8% of pneumonia caused by positive-gram aerobes. Negative-gram aerobes were resistant strongly to third generation cephalosporin and fluoroquinolones, only sensitive to imipenem. S.aureus was resistant to oxacillin (87.5%) and sensitive to vancomicin
Pneumonia
;
Bacteria
;
Adult
8.Nucleotide analysis of restricted fragment DNA extremities for characterizing the restriction enzyme cutting activity
Journal of Medical Research 2003;23(3):105-108
Nucleotide analysis of restricted fragment DNA extremities at definite cut sizes identified: there were 3 extremities: flat; cross with DNA 5’; cross with DNA 5’. This study presented a method which able to characterize unknown restriction enzymes by analyzing the cutting extremities of restricted fragments. The method is based on Sanger sequencing of DNA around the cut site and non-radioactive chemical. Klenow reaction had two active characters: analyzing DNA 5’3’ and exonucleasa 3’5’, allowing to determine the type of cutting of restrictive enzymes. This results allowed to identify the cut sizes of two new enzymes: for Sml1, the cut sites occurs within the recognition nucleotide sequence; BciVI recognizing a non-palindrome sequence and cuts outside this sequence.
DNA
;
Nucleotides
;
analysis
;
extremities
;
Enzymes
9.Some anthropometric indicator in puplils at Sapa and Yen Binh regions
Journal of Preventive Medicine 2003;13(2):49-52
This cross-sectional study involved 339 students aged 12-15 at 2 boarding schools in Sapa and Yen Binh, determined height, weight, and BMI. Results: there weren’t
significant differences between the weights (Sapa’s students: 34.38 kg, and Yen Binh’s students: 33.31 kg), and the average heights of students in 2 regions (p>0.05); but BMI of Sapa’s students is higher than Yen Binh’s students (17.04 vs 16.38, p<0.05)
Indicators and Reagents
;
Preventive Medicine
;
Public Health
10.Vital respiratory indexes of secondary school students at Sapa and Yen Binh
Journal of Preventive Medicine 2003;13(2):53-56
This cross-sectional study involved 339 students aged 12-15 at Sapa and Yen Binh regions. It measured and compared indexes such as vital capacity (VC), forced expiratory volume 1 (FEV1), and Tiffeneau index. Results: there weren’t significant differences between VC, FEV1 and Tiffeneau indexes of students in both sexes of 2 regions (p<0.05). There is a close correlation between VC and height of student (r>0.9), and between FEV1 and height (r>0.9)
Preventive Medicine
;
Public Health
;
Alkalosis, Respiratory