No abstract available.
Animals ; Cricetinae* ; Fertilization in Vitro* ; Humans*

One hundred and thirty-eight strains of Mycobacterium tuberculosis isolated from the 7th nationwide tuberculosis prevalence survey in 1995 were subjected to the restriction fragment length polymorphism (RFLP) analysis using IS6110 probe to define the representative fingerprinting patterns of Korean strains of M. tuberculosis and to evaluate the usefulness of DNA fingerprinting in tracing the transmission link of M. tuberculosis. Among 138 strains, 129 different IS6l10 RFLP types were identified. The number of bands in IS6110 RFLP types diversed from 1 to 20, and the majority (75%) was 9 to 14 bands. The RFLP patterns of 8 out of 15 strains isolated from the follow-up survey of one and half year later after the 7th national TB prevalence survey were unchanged when compared with previous RFLP patterns. Fifteen (11%) out of 138 strains were grouped in 6 IS6110 clusters; 2 with 10 copies, 2 with 12 copies, 1 with 14 copies, and 1 with 17 copies. These clusters were unable to be subclassified by IS1081 or (GTG) probes except one cluster by pTBN12 probe. The transmission links of 2 clusters were deducible; one from household and another from neighborhood, but those of remaining clusters were unclear because they had no contact one another. The results suggest that vigorous transmissions in tuberculosis are still progressing in Korea.
Dermatoglyphics ; DNA Fingerprinting* ; DNA* ; Family Characteristics ; Follow-Up Studies ; Korea ; Mycobacterium tuberculosis* ; Mycobacterium* ; Polymorphism, Restriction Fragment Length ; Prevalence* ; Residence Characteristics ; Tuberculosis*

The thirty eight newborn infants with periventricular leukomalacia who were admitted to the neonatal intensive care unit of Gil General Hospital from March 1, 1988 to June 30, 1991, were investigated for ultrasonographic findings, risk factors and neurological outcome. The results were as follows: 1) There were 38 cases of PVL including 21 echogenic flarings and 17 cystic PVL's. 2) Mean birth weight was 2,250 gm and mean gestational age was 35 week. 3) Mean detection timing was 4th day in echogenic flarings and 18th day in cystic PVL's. 4) PVL's were located in the parietal region in 1 case and fronto-parieto-occipital in 3 cases. 5) Mean cyst size was 6 mm. 6) Multiple logistic regression analysis for the risk factors of PVL showed that low birth weight, apnea and seizure were the most significant contributing factors (p<0.05). 7) In the follow-up study of cystic PVL's, 7 cases showed improvement, 7 cases developed into multicystic encephalomalacia and 3 cases developed into atrophy. 8) Neurodevelopmental outcome of cystic PVL's showed nomal; 6.2%, minor neurodevelopmental defect; 43.8%, major neurodevelopmental defect; 31.2% and death; 18.8%. 9) Neurosonographic predictability for neurodevelopemental sequelae by cystic PVL's showed sensitivity; 63.6%%, specificity; 98.0%, positive predictive value; 92.8% and accuracy; 88.2%. 10) Major neurodevelopmental defect was more frequent, cyst size being larger and location being more extensive (p<0.05).
Apnea ; Atrophy ; Birth Weight ; Encephalomalacia ; Follow-Up Studies ; Gestational Age ; Hospitals, General ; Humans ; Infant, Low Birth Weight ; Infant, Newborn ; Intensive Care, Neonatal ; Leukomalacia, Periventricular* ; Logistic Models ; Rabeprazole ; Risk Factors* ; Seizures ; Sensitivity and Specificity

The clinical observation was made on 117 operated cases of renal tuberculosis in Department of Urology, Catholic Medical College, during the period from 1970 to l979. The results were as follows: 1. Among 117 cases of the renal tuberculosis, 91 (77.8%) were unilateral and 26 (22.2%) were bilateral renal tuberculosis. Among 81 cases of the ureteral stricture complicated by renal tuberculosis, 55 (60.4%) were unilateral and 26 (39.6%) were bilateral renal tuberculosis. Contracted bladder was represented in 42 cases (35.9%). 2. Ureteral reimplantation was performed in 13 cases. Among 7 cases of the anti-reflux method, 2 cases were failed, 1 case of Boari operation was dead, but 5 cases of direct method were all successful. 3. Among 5 cases of the ileocystoplasty, 4 were in good result but 1 case had small amount of residual urine. Among 6 cases of the ureteroileocystoplasy, 1 case was dead and 1 case was performed secondary nephrectomy after previous operation. One of 2 cases of the ileal substitution of the ureter was dead. 4. There was no complication in 65 cases of simple nephrectomy and 2 cases of partial nephrectomy. 5. Of 50 cases of the total patients, except 65 cases of simple nephrectomy only and 2 cases of partial nephrectomy, 5 cases were complicated and 1 cases were dead. The complications were ureteral strictures at the site of reimplantation in 6, urinary fistulas in 2 and wound infection in 1. The causes of death were sepsis in 2, uremia with sepsis in 1 and acute renal failure in 1.
Acute Kidney Injury ; Cause of Death ; Constriction, Pathologic ; Humans ; Nephrectomy ; Replantation ; Sepsis ; Tuberculosis ; Tuberculosis, Renal* ; Uremia ; Ureter ; Urinary Bladder ; Urinary Fistula ; Urinary Tract* ; Urology ; Wound Infection

A clinical observation was made on 31 partial nephrectomized patients in Department of Urology, Catholic Medical College, during the period from January 1976 to December 1980. The results were as follow: 1. The common age group in 3rd and 4th decades and the proportion of male to female was 1.4 : 1. 2. Among 31 cases, renal stone was 18 (58.0%). renal tuberculosis was 7 (22.6%), renal rupture was 2 (6.5%). double pelvis was 2 (6.5%), renal infarction was 1 (3.2%) and renal carbuncle was 1 (3.2%). 3. of 31 cases, partial nephrectomy was performed in 33 cases. As methods of the operation, Guillotine type with "U" shaped mattress suture was 19 cases (57.6%) and Renal Vessel Clamp type wag 14 cases (42.4%). 4. Postoperative complication were gross hematuria in 4 cases, temporary urine leakage in 4 cases, wound infection in 1 case, residual stone in 1 case, delayed bleeding in 1 case, septic condition in l case and death in 1 case.
Carbuncle ; Female ; Hematuria ; Hemorrhage ; Humans ; Infarction ; Male ; Nephrectomy ; Pelvis ; Postoperative Complications ; Rupture ; Sutures ; Tuberculosis, Renal ; Urology ; Wound Infection

No abstract available.
DNA* ; Mycobacterium tuberculosis* ; Mycobacterium*

No abstract available.
DNA* ; Mycobacterium tuberculosis* ; Mycobacterium*

No abstract available.
alpha-Fetoproteins ; Common Bile Duct* ; Endoderm* ; Endodermal Sinus Tumor*

BACKGROUND: Autoimmune hemolytic anemias are characterized by autoantibodies recognizing antigens on the Individual's own red blood cells, resulting in immune- mediated hemolysis. Blood transfusions have been regarded as hazardous in patients with autoimmune hemolytic anemia (AIHA) because of potential intensification of hemolysis and a presumed high incidence of alloimmunization. METHODS: We examined the pretransfusion and posttransfusion hemoglobin levels in 6 patients with autoantibodies in their sera, which showed panagglutinations with all bloods tested in the compatibility testing. They received 'least' incompatible blood because of inability to find compatible blood. RESULTS: When we compared pretransfusion hemoglobin level with posttransfusion hemoglobin level, in 5 of 6 patients with AIHA, the hemoglobin levels were increased after red cell transfusion. 4 patient who did not respond to transfusion therapy initially had an increase in hemoglobin level after steroid treatment. Any signs or symptoms indicating hemolytic transfusion reaction were not observed ducting the transfusion period in all patients. CONCLUSIONS: The decision to transfuse in AIHA should consider multiple factors including the patient's clinical status, the potential benefit of transfusion, the potential response to other therapeutic modalities, but must never be regarded as contraindicated, even though the compatibility test may be strongly incompatible.
Anemia, Hemolytic* ; Anemia, Hemolytic, Autoimmune ; Autoantibodies ; Blood Group Incompatibility ; Blood Transfusion ; Erythrocyte Transfusion* ; Erythrocytes* ; Hemolysis ; Humans ; Incidence

BACKGROUND: Autoimmune hemolytic anemias are characterized by autoantibodies recognizing antigens on the Individual's own red blood cells, resulting in immune- mediated hemolysis. Blood transfusions have been regarded as hazardous in patients with autoimmune hemolytic anemia (AIHA) because of potential intensification of hemolysis and a presumed high incidence of alloimmunization. METHODS: We examined the pretransfusion and posttransfusion hemoglobin levels in 6 patients with autoantibodies in their sera, which showed panagglutinations with all bloods tested in the compatibility testing. They received 'least' incompatible blood because of inability to find compatible blood. RESULTS: When we compared pretransfusion hemoglobin level with posttransfusion hemoglobin level, in 5 of 6 patients with AIHA, the hemoglobin levels were increased after red cell transfusion. 4 patient who did not respond to transfusion therapy initially had an increase in hemoglobin level after steroid treatment. Any signs or symptoms indicating hemolytic transfusion reaction were not observed ducting the transfusion period in all patients. CONCLUSIONS: The decision to transfuse in AIHA should consider multiple factors including the patient's clinical status, the potential benefit of transfusion, the potential response to other therapeutic modalities, but must never be regarded as contraindicated, even though the compatibility test may be strongly incompatible.
Anemia, Hemolytic* ; Anemia, Hemolytic, Autoimmune ; Autoantibodies ; Blood Group Incompatibility ; Blood Transfusion ; Erythrocyte Transfusion* ; Erythrocytes* ; Hemolysis ; Humans ; Incidence