With the results obtained from study realized on 90 "normal" elderly subjects and 686 elderly patients with hypertension and/or diabetes showed that: There is no difference on intima-media thickness (IMT) of carotid artery and its bifurcation between right site and left site. The average IMT at common carotid artery and its bifurcation between is sinificantly higher in elderly patients with hypertension and/or diabetes than in "normal" elderly subjects. The rate of thickness of carotid IMT and its birfucation in the elderly with hypertension and/or diabetes is significantly higher than "normal" elderly subjects. This rate has no difference between age-groups but significantly higher in men.
Ultrasonography ; Aged ; Hypertension ; Diabetes Mellitus

The study aimed to determine the normal range of the intima-media thickness that was measured in common carotid artery and carotid groove and evaluate the changes in measurement with age in 200 healthy adults (113 males, 87 females, from 15 to 93 years old) between August 1998 and December 1999. Results: On average, the intima-media thickness is 0.7+/-0.16 mm in common carotid artery and is 0.87+/-0.25 mm in carotid groove. There is not difference in the intima-media thickness of common carotid and carotid groove between left and right. The intima-media thickness of both common carotid artery and carotid groove is increased over age. There is a linear correlation between the intima-media thickness with age. The intima-media thickness of common carotid artery, but not of carotid groove, is higher in men than in women
ultrasonography ; Carotid Arteries

200 persons, average age is 59,27 (from 15-93) without vascular risk factors were studied by colour Duplex scanning. Results showed that average systolic velocity in common carotid arteries is 81,14 +/- 14,67 cm/s, average diastolic velocity is 23,27 +/- 5,15 cm/s, average diastolic velocity is 25,53 +/- 5,21 cm/s. Average systolic velocity in vertebral arteries is 42,58 +/- 7,73cm/s, average diastolic velocity is 14,68 +/- 3,63 cm/s. No statistic significantly difference of these parameters between men and women. No statistic difference of these parameters between right and left side. Systolic and diastolic velocities in common and internal carotid arteries decrease significantly with age. Other parameters do not change clearly with age
ultrasonography ; Carotid Arteries

Study was performed on 750 old persons of two groups. Group 1 of 661 subjects with one or more risk factors of atherosclerosis such as high blood pressure, diabetes, blood lipid disorder, smoking, obesity; group 2 of 89 healthy subjects. Results showed that in group with risk factor, the thickness of middle internal membrane of primitive carotid aorta is thicker than that in healthy group. The more risk factors the thicker middle internal membrane
Atherosclerosis ; Carotid Artery Diseases ; Aged ; Ultrasonics

Phytochemical investigation of Kandelia candel resulted in the isolation of six triterpenes (1 - 5) and two glyceryl glycosides (6 and 7) and their structures were determined by comparing the spectroscopic data with those of reported values. In present study, we described the inhibitory effects of fractions and isolated compounds from K. candel on pro-inflammatory cytokines (IL-12 p40, IL-6, and TNF-alpha) production in lipopolysaccharide (LPS) stimulated bone marrow-derived dendritic cells (BMDCs). Results indicated that compounds 3, 6, and 7 showed potent inhibition on IL-6 production (IC50 values at less than 0.5 microM, respectively). Meanwhile, compounds 6 and 7 exhibited strong inhibitory effects on the production of TNF-alpha (IC50 values of 1.7 +/- 0.1 and 5.5 +/- 0.2 microM). Compounds 1 and 3 were also showed the inhibitory effects on IL-12 p40 production (IC50 values of 8.9 +/- 0.4 and 3.3 +/- 0.1 microM, respectively).
Cytokines ; Dendritic Cells ; Glycosides* ; Interleukin-12 ; Interleukin-6 ; Rhizophoraceae* ; Triterpenes* ; Tumor Necrosis Factor-alpha

As authorities braced for the arrival of the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), infrastructure investments and government directives prompted action in central Viet Nam to establish capacity for genomic surveillance sequencing. From 17 November 2021 to 7 January 2022, the Pasteur Institute in Nha Trang sequenced 162 specimens from 98 150 confirmed SARS-CoV-2 cases in the region collected from 8 November to 31 December 2021. Of these, all 127 domestic cases were identified as the B.1.617.2 (Delta) variant, whereas 92% (32/35) of imported cases were identified as the B.1.1.529 (Omicron) variant, all among international flight passengers. Patients were successfully isolated, enabling health-care workers to prepare for additional cases. Most (78%) of the 32 Omicron cases were fully vaccinated, suggesting continued importance of public health and social measures to control the spread of new variants.