3.Renojejunal fistula: an extremely rare form of renoenteric fistula.
Annals of the Academy of Medicine, Singapore 2010;39(5):417-418
Humans
;
Intestinal Fistula
;
etiology
;
Jejunal Diseases
;
etiology
;
Kidney Diseases
;
etiology
;
Kidney Pelvis
;
Male
;
Middle Aged
;
Psoas Abscess
;
complications
;
Urinary Fistula
;
etiology
5.A case of primary hyperparathyroidism with hypercalcemic nephropathy in children.
Jae Myung YU ; Heui Jung PYO ; Dong Seop CHOI ; Kang Woo LEE ; Kee Hwan YOO ; Chong Suk KIM
Journal of Korean Medical Science 1994;9(3):268-272
Primary hyperparathyroidism is a rare disease in children and is characterized by conspicuous skeletal and renal changes. A 12 year old male patient presented with symptoms of polydipsia, polyuria, general weakness, nausea, and vomiting which had begun 3 months earlier, and showed typical laboratory findings of primary hyperparathyroidism. Confirmatory diagnosis was made by elevated parathyroid hormone concentration in serum, technetium-thallium subtraction scan imaging method and histopathologic finding of chief cell hyperplasia. The laboratory findings revealed elevated levels of BUN, creatinine and decreased GFR. Kidney biopsy showed typical calcium deposits in tubules with marked tubulointerstitial infiltration. After subtotal parathyroidectomy, clinical findings improved remarkably.
Case Report
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Child
;
Human
;
Hypercalcemia/*etiology
;
Hyperparathyroidism/*complications/pathology
;
Hyperplasia
;
Kidney/pathology
;
Kidney Diseases/*etiology
;
Male
;
Parathyroid Glands/pathology
6.Effects of mycophenolate mofetil on renal interstitial fibrosis after Unilateral ureteral obstruction in rats.
Chun, ZHANG ; Zhonghua ZHU ; Gang, WANG ; Anguo, DENG
Journal of Huazhong University of Science and Technology (Medical Sciences) 2003;23(3):269-70, 282
To investigate the effects of mycophenolate mofetil (MMF) on the process of renal interstitial fibrosis, unilateral ureteral obstruction (UUO) model was established in rats. Twenty Sprague-Dawley rats underwent UUO and received vehicle (n = 10) or MMF (20 mg.kg-1.d-1, by daily gastric gavage, n = 10) during a period of 5 days following surgery, and the additional 10 rats were served as sham-operated group. The rats were killed 5 days after surgery. Immunohistochemistry was performed on renal tissue for proliferating cell nuclear antigen (PCNA), alpha-smooth muscle actin (alpha-SMA) and type I and III collagen (col I, col III). Histological studies were also done by MASSON staining. Five days after surgery, proliferating cells in tubules, interstitium as well as interstitial myofibroblast (MyoF) infiltration and interstitial col I, col III deposition were all significantly reduced by MMF treatment. MMF also alleviated the histological changes of UUO rats. These results suggested that the reduction of interstitial MyoF infiltration may be an important event by which MMF prevents renal injury caused by UUO and MMF could be used to limit the progression of renal fibrosis.
Fibrosis
;
Kidney/*pathology
;
Kidney Diseases/etiology
;
Kidney Diseases/pathology
;
Kidney Diseases/*prevention & control
;
Mycophenolic Acid/*analogs & derivatives
;
Mycophenolic Acid/*pharmacology
;
Random Allocation
;
Rats, Sprague-Dawley
;
Ureteral Obstruction/*complications
7.A Case of Post-Streptococcal Glomerulonephritis with Diffuse Alveolar Hemorrhage.
Hye Young SUNG ; Chang Hoon LIM ; Mi Jung SHIN ; Byung Soo KIM ; Young Ok KIM ; Ho Chul SONG ; Suk Young KIM ; Euy Jin CHOI ; Yoon Sik CHANG ; Byung Kee BANG
Journal of Korean Medical Science 2007;22(6):1074-1078
Acute post-streptococcal glomerulonephritis (PSGN) is characterized by an abrupt onset of edema, hypertension, and hematuria. Life-threatening diffuse alveolar hemorrhage (DAH) is rarely associated with acute PSGN. There have been only two reported cases worldwide, and no case has been reported previously in Korea. Here, we present a patient who clinically presented with pulmonary-renal syndrome; the renal histology revealed post-infectious glomerulonephritis of immune complex origin. A 59-yr-old woman was admitted with oliguria and hemoptysis two weeks after pharyngitis. Renal insufficiency rapidly progressed, and respiratory distress developed. Chest radiography showed acute progressive bilateral pulmonary infiltrates. The clinical presentation suggested DAH with PSGN. Three days after treatment with high-dose steroids, the respiratory distress and pulmonary infiltrates resolved. Electron microscopy of a renal biopsy specimen sample revealed diffuse proliferative glomerulonephritis with characteristic subendothelial deposits of immune complex ("hump''). The renal function of the patient was restored, and the serum creatinine level was normalized after treatment.
Biopsy
;
Female
;
Glomerulonephritis/*etiology
;
Hemorrhage/*etiology
;
Humans
;
Kidney/pathology
;
Lung Diseases/etiology
;
Middle Aged
;
*Pulmonary Alveoli
;
Streptococcal Infections/*complications
8.Rhabdomyolysis in children: a case report.
Hong-mei QIAO ; Huan-ji CHENG ; Hong-bo WANG
Chinese Journal of Pediatrics 2013;51(2):150-152
Biomarkers
;
analysis
;
Biopsy
;
Child
;
Female
;
Fluid Therapy
;
Humans
;
Kidney Diseases
;
etiology
;
Rhabdomyolysis
;
diagnosis
;
etiology
;
therapy
;
Virus Diseases
;
complications
9.New Biomarkers of Acute Kidney Injury and the Cardio-renal Syndrome.
The Korean Journal of Laboratory Medicine 2011;31(2):72-80
Changes in renal function are one of the most common manifestations of severe illness. There is a clinical need to intervene early with proven treatments in patients with potentially deleterious changes in renal function. Unfortunately progress has been hindered by poor definitions of renal dysfunction and a lack of early biomarkers of renal injury. In recent years, the definitional problem has been addressed with the establishment of a new well-defined diagnostic entity, acute kidney injury (AKI), which encompasses the wide spectrum of kidney dysfunction, together with clearer definition and sub-classification of the cardio-renal syndromes. From the laboratory have emerged new biomarkers which allow early detection of AKI, including neutrophil gelatinase-associated lipocalin (NGAL) and cystatin C. This review describes the new concepts of AKI and the cardio-renal syndromes as well as novel biomarkers which allow early detection of AKI. Panels of AKI biomarker tests are likely to revolutionise the diagnosis and management of critically ill patients in the coming years. Earlier diagnosis and intervention should significantly reduce the morbidity and mortality associated with acute kidney damage.
Acute Kidney Injury/*diagnosis
;
Biological Markers/analysis/blood/urine
;
Cystatin C/blood/urine
;
Heart Failure/complications/etiology
;
Humans
;
Kidney Diseases/complications/*diagnosis/etiology
;
Lipocalins/blood/urine
;
Syndrome
10.Periodontal Status of Chronic Renal Failure Patients Receiving Hemodialysis.
Ismail MARAKOGLU ; Ulvi Kahraman GURSOY ; Serhat DEMIRER ; Hafize SEZER
Yonsei Medical Journal 2003;44(4):648-652
Host factors such as systemic diseases, genetic polymorphism or drug usage play a major role in the pathogenesis of periodontal disease by modifying the host response to periodontal infection or altering the susceptibility to infection by periodontal organisms. This study was designed to evaluate the clinical response of patients receiving hemodialysis to existing microbial dental plaque. Gingival Index (GI) and Plaque Index (PI) scores and probing depths (PD) were recorded for the entire dentition on 36 chronic renal failure patients receiving hemodialysis (H) and 36 systemically healthy individuals (C), matched with the patient group, based on age and extent of plaque accumulation. No statistically significant difference was observed in the clinical parameters between the two groups (PI: t=1.69 p= 0.096; GI: t=1.057 p=0.294; PD: t=0.01 p=0.99). In the present study, H patients revealed a similar response to existing bacterial plaque and their periodontal status was comparable to that of the control group. Although patients receiving hemodialysis have been suggested to present a certain degree of immunosuppression, based on the findings of the present study chronic renal failure does not seem to be an additional risk factor for more severe periodontal destruction.
Adult
;
Aged
;
Female
;
Human
;
Kidney Failure, Chronic/*complications/*therapy
;
Middle Aged
;
Periodontal Diseases/*etiology
;
*Renal Dialysis