2.Clinical manifestation and ultrasonic characteristics of five patients with acute arsenic poisoning.
Jie-ming LIN ; Chao-qiang JIANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2003;21(6):420-422
OBJECTIVETo study the clinical manifestation and ultrasonic characteristics of liver, kidney and heart of five patients with acute arsenic poisoning.
METHODSThe activity of serum myocardial enzymes, function of liver and kidney, and urinary As concentrations were measured. HDI 3000 Enhanced, and Toshiba 38A two dimensional ultrasound was used to examine the ultrasonic echogram of heart, liver, kidney of the patients.
RESULTS(1) The arsenic concentrations in the urine (1.9 approximately 15.6 micromol/L) were higher than the normal value (1.17 micromol/L) in these patients (blood dialytic fluid of one patient with anuria was measured); (2) Four of them had increased WBC, or anemia, and abnormal urine routine to various degree; (3) The activities of serum myocardial enzymes (CK, AST, LDH and HBDH) in 4 patients were at least 2 items increased; (4) Serum bilirubin and urea nitrogen in all patients were increased; (5) The ultrasonic echogram of liver and kidney in these 5 patients showed abnormality to various degree, one of them had slight enlargements in left atrium and ventricle as well as a little pericardial fluid.
CONCLUSIONThe clinical manifestation and ultrasonic characteristics of liver, kidney, and heart were consistent with the pathologic changes in acute arsenic poisoning. Early blood dialysis may reduce visceral damage.
Acute Disease ; Adult ; Arsenic Poisoning ; complications ; diagnostic imaging ; physiopathology ; Heart ; physiopathology ; Humans ; Kidney ; diagnostic imaging ; physiopathology ; Liver ; diagnostic imaging ; physiopathology ; Male ; Ultrasonography
3.Tuberous sclerosis and polycystic kidney disease: A case report.
Ki Chul CHOI ; Soo Wan KIM ; Nam Ho KIM ; Young Joon KANG
Journal of Korean Medical Science 1996;11(6):526-531
Polycystic kidney disease is a relatively uncommon finding of tuberous sclerosis. Furthermore, the renal insufficiency by the severe polycystic kidney disease is extremely rare in tuberous sclerosis. The patient was a 27-year-old man, complaining of generalized seizure and progressive abdominal distension. His clinical features were chracterized by epilepsy, mental retardation, skin abnormalities including adenoma sebaceum, shagreen patch and ash-leaf spots. Abdominal computed tomography demonstrated numerous variable sized cysts throughout both kidneys. Clinical and laboratory findings revealed chronic renal failure due to severe polycystic kidneys. On reviewing the literature, the present case is the first report of polycystic kidneys associated with tuberous sclerosis in Korea.
Adult
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Brain/pathology
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Human
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Magnetic Resonance Imaging
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Male
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Polycystic Kidney Diseases/*complications/pathology/physiopathology/ultrasonography
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Tomography, X-Ray Computed
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Tuberous Sclerosis/*complications/pathology/physiopathology/ultrasonography
4.Quantitative evaluation of contrast-enhanced ultrasound in the early diagnosis of acute renal failure of rabbits.
Yi DONG ; Wen-Ping WANG ; Hong DING ; Xi-Yuan LIN ; Pei-Li FAN ; Jia-Ying CAO ; Ben-Hua XU
Acta Academiae Medicinae Sinicae 2008;30(1):45-48
OBJECTIVETo evaluate the early diagnostic value of contrast-enhanced ultrasound (CEUS) in acute renal failure (ARF) of rabbit.
METHODSThe rabbit model of ARF was established by intramuscular injection of 50% glycerin (12 ml/kg) into the hind legs of 18 New Zealand rabbits. CEUS was performed for both kidneys before injection and 6 hours after the injection. The slope rate of ascending curve (A), the slope rate of descending curve (alpha), area under curve (AUC), derived peak intensity (DPI), and time to peak (TTP) were measured in renal cortex of rabbits using Q-lab software package. Blood serum urea nitrogen (BUN) and serum creatinine (SCr) were measured.
RESULTSThe values of A and alpha before the injection of glycerin were (3.07 +/- 1.83) dB/s and (0.19 +/- 0.15)/s, respectively, which were significantly higher than the values after injection [ (2.76 +/- 1.31) dB/s and (0.09 +/- 0.02)/s, respectively] (P < 0.05). The values of AUC and TTP before the injection of glycerin were (137.4 +/- 68.4) dB s and (6.33 +/- 3.71) s, which were significantly lower than the values after injection [(309.5 +/- 88.9) dB s and (8.61 +/- 3.97) s, respectively] (P < 0.01). No significant change of DPI, BUN or SCr was found.
CONCLUSIONSCEUS can precisely display the hemodynamic change of ARF model of rabbit in the early stage, with superior sensitivity than BUN and SCr. It may be a promising imaging method for the early diagnosis of ARF.
Acute Kidney Injury ; diagnostic imaging ; physiopathology ; Animals ; Blood Urea Nitrogen ; Contrast Media ; Creatinine ; blood ; Early Diagnosis ; Rabbits ; Ultrasonography
5.Delayed redo pyeloplasty fails to recover lost renal function after failed pyeloplasty: Early sonographic changes that correlate with a loss of differential renal function.
Doo Yong CHUNG ; Chang Hee HONG ; Young Jae IM ; Yong Seung LEE ; Sang Woon KIM ; Sang Won HAN
Korean Journal of Urology 2015;56(2):157-163
PURPOSE: To evaluate changes in differential renal function (DRF), as a functional outcome, in children who underwent redo pyeloplasty for management of failed pyeloplasty and to examine the factors that affect functional outcomes. MATERIALS AND METHODS: Between January 2002 and November 2010, a total of 18 patients who underwent redo pyeloplasty for persistent ureteropelvic junction obstruction after failed pyeloplasty were enrolled in this study. We assessed perioperative factors and evaluated changes in renal cortical thickness (RCT), renal function, and hydronephrosis by use of serial ultrasound and diuretic renography. RESULTS: The mean follow-up period was 44.83+/-28.86 months. After redo pyeloplasty, prevention of further functional deterioration was observed in only 12 of the 18 patients. After dividing the patients according to this observation, we discovered significant differences in both change in DRF (dDRF) and change in RCT (dRCT) (difference between before and after initial pyeloplasty) between the two groups (p<0.001). Additionally, we noted a significant positive correlation between dRCT and dDRF. All patients showed improvements in hydronephrosis grade and relief of symptoms compared with before redo pyeloplasty. CONCLUSIONS: Redo pyeloplasty should be considered in cases of failed pyeloplasty to preserve renal function and obtain relief from symptoms. If patients show severe deterioration of DRF or a decrease in RCT after initial pyeloplasty, preservation of DRF in these patients after redo pyeloplasty could be difficult. Therefore, redo pyeloplasty should be performed before severe deterioration of DRF or decrease in RCT.
Adolescent
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Child
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Child, Preschool
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Disease Progression
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Female
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Follow-Up Studies
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Humans
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Hydronephrosis/etiology/ultrasonography
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Infant
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Kidney/*physiopathology/ultrasonography
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Kidney Cortex/pathology
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Kidney Function Tests/methods
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Kidney Pelvis/*surgery/ultrasonography
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Male
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Postoperative Period
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Prognosis
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Reoperation/adverse effects/methods
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Retrospective Studies
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Treatment Failure
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Treatment Outcome
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Ureteral Obstruction/complications/pathology/*surgery
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Ureteral Obstruction/*surgery
6.Correlation between renal artery resistance index and serum creatinine level early after renal transplantation.
Jun HUANG ; Ying WU ; Ze-xuan SU ; Yu-min ZHUO
Journal of Southern Medical University 2011;31(6):1105-1106
OBJECTIVETo investigate the relationship between the resistance index (RI) of the renal artery and serum creatinine (Cr) level in patients early (within one month) after renal transplantation.
METHODSA total of 123 patients receiving renal transplantation underwent examinations by color Doppler ultrasound for measurement of the RI of the renal artery within one month after the operation. According to the results of RI measurement, the patients were divided into RI≥0.75 and RI<0.75 groups for analyzing the correlation between RI and serum Cr level measured at the same time points.
RESULTSThe RI and Cr levels in patients with RI≥0.75 showed a significant positive correlation (P<0.05), whereas they showed an inverse correlation in patients with RI<0.75 (P<0.05). The patients with RI≥0.75 had significantly lower RI of the renal artery and Cr level than those with RI≥0.75.
CONCLUSIONRI is significantly correlated to Cr, and may serve as an indicator for predicting renal graft function after transplantation.
Adolescent ; Adult ; Aged ; Creatinine ; blood ; Female ; Humans ; Kidney Transplantation ; Male ; Middle Aged ; Postoperative Period ; Renal Artery ; diagnostic imaging ; physiopathology ; Ultrasonography, Doppler ; Vascular Resistance ; Young Adult
7.The Impact of Hemodialysis and Arteriovenous Access Flow on Extracranial Hemodynamic Changes in End-Stage Renal Disease Patients.
Sarah CHUNG ; Hye Seon JEONG ; Dae Eun CHOI ; Hee Jung SONG ; Young Gi LIM ; Joo Yeon HAM ; Ki Ryang NA ; Kang Wook LEE
Journal of Korean Medical Science 2016;31(8):1239-1245
In this study, we characterized cerebral blood flow changes by assessment of blood flow parameters in neck arteries using carotid duplex ultrasonography and predictive factors for these hemodynamic changes. Hemodynamic variables were measured before and during hemodialysis in 81 patients with an arteriovenous access in their arm. Hemodialysis produced significant lowering in peak systolic velocity and flow volume of neck arteries and calculated total cerebral blood flow (1,221.9 ± 344.9 [before hemodialysis] vs. 1,085.8 ± 319.2 [during hemodialysis], P < 0.001). Effects were greater in vessels on the same side as the arteriovenous access and these changes were influenced by arteriovenous access flow during hemodialysis, both in the CCA (r = -0.277, P = 0.015) and the VA (r = -0.239, P = 0.034). The change of total cerebral blood flow during hemodialysis was independently related with age, presence of diabetes, and systemic blood pressure.
Aged
;
Carotid Arteries/diagnostic imaging
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Cerebrovascular Circulation/*physiology
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Dizziness/etiology
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Female
;
Hemodynamics/*physiology
;
Humans
;
Kidney Failure, Chronic/*physiopathology
;
Male
;
Middle Aged
;
Renal Dialysis
;
Risk Factors
;
Ultrasonography, Doppler, Duplex
8.The Impact of Hemodialysis and Arteriovenous Access Flow on Extracranial Hemodynamic Changes in End-Stage Renal Disease Patients.
Sarah CHUNG ; Hye Seon JEONG ; Dae Eun CHOI ; Hee Jung SONG ; Young Gi LIM ; Joo Yeon HAM ; Ki Ryang NA ; Kang Wook LEE
Journal of Korean Medical Science 2016;31(8):1239-1245
In this study, we characterized cerebral blood flow changes by assessment of blood flow parameters in neck arteries using carotid duplex ultrasonography and predictive factors for these hemodynamic changes. Hemodynamic variables were measured before and during hemodialysis in 81 patients with an arteriovenous access in their arm. Hemodialysis produced significant lowering in peak systolic velocity and flow volume of neck arteries and calculated total cerebral blood flow (1,221.9 ± 344.9 [before hemodialysis] vs. 1,085.8 ± 319.2 [during hemodialysis], P < 0.001). Effects were greater in vessels on the same side as the arteriovenous access and these changes were influenced by arteriovenous access flow during hemodialysis, both in the CCA (r = -0.277, P = 0.015) and the VA (r = -0.239, P = 0.034). The change of total cerebral blood flow during hemodialysis was independently related with age, presence of diabetes, and systemic blood pressure.
Aged
;
Carotid Arteries/diagnostic imaging
;
Cerebrovascular Circulation/*physiology
;
Dizziness/etiology
;
Female
;
Hemodynamics/*physiology
;
Humans
;
Kidney Failure, Chronic/*physiopathology
;
Male
;
Middle Aged
;
Renal Dialysis
;
Risk Factors
;
Ultrasonography, Doppler, Duplex
9.Tissue Doppler-derived E/e' ratio as a parameter for assessing diastolic heart failure and as a predictor of mortality in patients with chronic kidney disease.
Min Keun KIM ; Biro KIM ; Jun Young LEE ; Jae Seok KIM ; Byoung Geun HAN ; Seung Ok CHOI ; Jae Won YANG
The Korean Journal of Internal Medicine 2013;28(1):35-44
BACKGROUND/AIMS: Diastolic dysfunction occurs frequently in patients with chronic kidney disease (CKD) and is associated with heart failure (HF) or mortality. We investigated whether the ratio of early diastolic mitral inflow velocity to early diastolic mitral annulus velocity (E/e' ratio), estimated using tissue Doppler imaging, has prognostic value for cardiovascular morbidity and all-cause mortality in patients with CKD. METHODS: For 186 patients with CKD of stages III to V, we obtained echocardiograms with tissue Doppler imaging. A 5-year follow-up of 136 patients was performed based on hospital records and telephone interviews. The enrolled patients (79 males and 57 females) were categorized into the following CKD subgroups: stage III (n = 25); stage IV (n = 22); and stage V (n = 89). RESULTS: The average follow-up period was 30.45 months and the mean age of the patients was 61.13 years. The mortality rate after 5 years was 60.0%. The causes of death were: sepsis, 21.9%; HF, 16.2%; and sudden death, 15.2%. Age (p = 0.000), increased C-reactive protein level (p = 0.018), and increased E/e' ratio (p = 0.048) were found to correlate with mortality. Age (p = 0.000), decreased ejection fraction (p = 0.003), and increased E/e' ratio (p = 0.045) correlated with cardiovascular event. CONCLUSIONS: The E/e' ratio can predict mortality and cardiovascular events in patients with CKD who have diastolic dysfunction.
Aged
;
Chi-Square Distribution
;
*Echocardiography, Doppler
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Female
;
Glomerular Filtration Rate
;
Heart Failure, Diastolic/*mortality/physiopathology/*ultrasonography
;
Humans
;
Incidence
;
Kaplan-Meier Estimate
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Kidney/physiopathology
;
Linear Models
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Male
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Middle Aged
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Mitral Valve/physiopathology/ultrasonography
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Predictive Value of Tests
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Prognosis
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Proportional Hazards Models
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ROC Curve
;
Renal Insufficiency, Chronic/diagnosis/*mortality/physiopathology
;
Republic of Korea/epidemiology
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Risk Assessment
;
Risk Factors
;
Stroke Volume
;
Time Factors
;
Ventricular Function, Left
10.Effects of the second renal transplantation on the sexual function of kidney recipients.
Lian-hui FAN ; Long LIU ; Jun XIANG ; Xiong-fei WU ; Rong-jie YU
National Journal of Andrology 2005;11(7):508-510
OBJECTIVETo investigate the effects of the second renal transplantation on sexual function.
METHODSThirty kidney graft recipients, including 29 cases of the second renal transplantation and 1 case of simultaneous dual kidney transplantation, responded to the questionnaire. The penis cavernosal artery flow of these patients were examined by color doppler ultrasonography. Of the 30 recipients, 9 underwent bilateral kidney transplantation with their bilateral external iliac arteries anastomosed to the donors' renal arteries (Group A), 10 recipients with their unilateral external iliac arteries and the other internal iliac arteries anastomosed to the donors' renal arteries (Group B), the other 10 with their internal iliac arteries anastomosed to the donors' renal arteries (Group C).
RESULTSEight recipients of Group A, 7 of Group B, and 5 of Group C were restored to normal sexual function 6 months after kidney transplantation. The peak systole velocity (PSV) in Group C was slower than in Groups A and B.
CONCLUSIONKidney transplantation with the second internal iliac arteries anastomosed to donors' renal arteries may affect the sexual function of the recipients, but some might enjoy satisfactory sexual life some time after the establishment of lateral branch circulation.
Adult ; Anastomosis, Surgical ; Humans ; Iliac Artery ; surgery ; Kidney Failure, Chronic ; physiopathology ; surgery ; Kidney Transplantation ; Male ; Middle Aged ; Penile Erection ; physiology ; Penis ; diagnostic imaging ; Renal Artery ; surgery ; Reoperation ; Surveys and Questionnaires ; Ultrasonography