1.Antibiotic Sensitivity and Spectrum of Bacterial Isolates in Otorhinolaryngological Infection: A Retrospective Study
Kian Joo Sia ; Ing Ping Tang ; MS ORL HNS ; Narayanan Prepageran
The Medical Journal of Malaysia 2013;68(1):6-9
Objectives: To identify the common bacteria of
otorhinolaryngological (ORL) infection in three general
hospitals in the state of Sarawak, East Malaysia and to
determine the antibiotic sensitivity of the common bacteria
to update local antibiotic policy.
Methods: All specimens with positive monoclonal culture,
received from inpatient and outpatient Otorhinolaryngology
Department in the year 2009 and 2010 were included in the
study. Patients’ demographics, nature of specimens,
bacterial isolates and antibiotic sensitivity were analysed by using the Statistical Package for the Social Sciences (SPSS).
Results: A total 244 positive monoclonal cultures were
identified. Staphylococcus species and Gram negative
bacilli were the commonest bacteria of ORL infections.
Common ORL bacteria remain sensitive to our front line
antibiotics. There are a number of multi-drug resistant
isolates of MRSA, ESBL Klebsiella pneumoniae and
Acinetobacter baumanii in the hospital-acquired infections.
Conclusion: Although resistance to antimicrobial agents is
growing worldwide, first line antibiotics still show significant therapeutic advantage in our local setting. The low resistance of bacterial isolates in our community reflects judicious use of antibiotics in our routine clinical practices.
2.Kimura’s Disease: Diagnostic Challenge and Treatment Modalities
Kian Joo Sia ; Catherine Khi Ling Kong ; Tee Yong Tan ; Ing Ping Tang
The Medical Journal of Malaysia 2014;69(6):281-283
Case Report: Five cases of Kimura’s disease had been
treated in our centre from year 2003 to 2010. All cases were
presented with head and neck mass with cervical
lymphadenopathy. Surgical excision was performed for all
cases. Definite diagnosis was made by histopathological
examination of the resected specimens. One out of five
cases developed tumour recurrence four years after
resection.
Conclusion: Surgical excision is our choice of treatment
because the outcome is immediate and definite tissue
diagnosis is feasible after resection. Oral corticosteroid
could be considered as an option in advanced disease.
However, tumour recurrence is common after cessation of
steroid therapy.