1.Classification and reconstruction of the injured digit distal to dip joint.
Dong Gil HAN ; Ki Young AHAN ; Dae Hwan PARK
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1992;19(3):499-506
No abstract available.
Classification*
;
Joints*
3.FRONTOTEMPORAL RECONSTRUCTION USING VARIOUS MATERIALS.
Ki Hwan HAN ; Heung Dong KIM ; Jin Sung KANG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1997;24(2):414-426
Based on our experience with 23 frontotemporal reconstructions performed, this paper attempts to provide guidelines for appropriate selection among the four most commonly employed materials (e.g., autogenous parietal bone, silicone rubber, methylmethacrylate, and porous polyethylene) so that optimal results can be achieved. Clinical follow-up ranged from 6 to 91 months (mean 32 months). Every patient was analyzed clinically by ordinary scale method. The mean defect size was 134.8 cm2 in the silicone rubber, 36.5 cm2 in the methylmethacrylate, 17.4 cm2 in the autogenous bone graft and 7.3 cm2 in the porous polyethylene. The clinical assessment was excellent (mean, 29.3 points) in silicone rubber, excellent (mean, 28.6 points) in autogenous bone, excellent (mean, 26.8 points) in methylmethacrylate, and good (mean, 24.8 points) in polyethylene. To sum up, a large bony defect of congenital calvarial anomaly produced an excellent result using custom-made silicone implant. A relatively small bony defect with a scarred bed produced an excellent result using autogenous parietal bone grafting. Unexpected and medium-sized defect was reconstructed successfully through a simple procedure using methylmethacrylate. Porous Polyethylene was used at an incidental small defect because of its expensiveness.
Cicatrix
;
Follow-Up Studies
;
Humans
;
Methylmethacrylate
;
Parietal Bone
;
Polyethylene
;
Silicone Elastomers
;
Transplants
4.Numerical aberrations of chromosome 17 and her2/neu gene amplification, her2/neu and p 53 protein expression in breast cancer.
Ki Taek HAN ; Young Hwan OH ; Poong LIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1998;25(8):1416-1425
Breast cancer is one of the leading causes of death attributable to cancer in women. In view of the limitations of conventional predictable factors of the breast cancer, additional second-generation parameters would be valuable in selecting the patients who would be most likely to be beneficial from adjuvant therapy and breast reconstruction. The author investigated the HER2/neu gene amplification and the number of chromosome 17 in 39 cases of paraffin embedded breast cancer tissues, 20 cases without lymph node metastasis and 19 cases with lymph node metastasis, using fluorescent in situ hybridization(FISH) and compared the results with HER2/neu and p 53 protein expression detected by immunohistochemical method. Eleven cases fibroadenoma were used as benign tumor control. Numerical aberrations of chromosome 17 were found in 17 out 39 breast cancer cases (44%)(monosomy in 10 cases, 26%; trisomy in 3 cases, 8%; tetrasomy in 3 cases, 8%; polysomy in 1 case ,3%), and the frequency of each type aberration was not significantly different between the negative and positive groups in lymph node metastasis. Monosomy of chromosome 17 was found in 2 out of 11(12%) fibroadenoma cases. HER2/neu gene amplification was found in 8 out of 39 cases (19%) and other 2 cases revealed HER2/neu gene amplification in lymph node metastatic tumor only, not in original tumor. Fourteen out of 19 cases of breast cancer with lymph metastasis showed HER2/neu protein expression both in original and metastatic tumors. All of the six cases showing HER2/neu gene amplification in original and/or metastatic tumor revealed HER2/neu protein expression. The frequency of HER2/neu gene amplification in the 39 breast cancer cases was not different between metastatic and non-metastatic groups(p= 0.284). However, HER2/neu protein expression was increased significantly in the metastatic group(p=0.028). None of the 11 fibroadenoma cases revealed HER2/neu gene amplification or HER2/ neu protein expression. Nine out of 19 cases of breast cancer with lymph node metastasis showed p 53 protein accumulation in original tumor(47%), but 3 of them revealed p 53 protein accumulation only in original tumor. The frequency of p 53 protein accumulation was not significantly different between metastatic and non-metastatic groups. None of the 11 fibroadenoma cases revealed p 53 protein accumulation. In conclusion, there are no differences between the lymph node metastatic group and non-metastatic groups in numerical aberrations of the chromosome 17 , amplification of the HER2/neu gene expression and accumulation of the p 53 protein in breast cancer. However, the HER2/neu protein expression was increased significantly in lymph node metastatic group, so it could be one of the predictors of the metastasis in breast cancer.
Breast Neoplasms*
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Breast*
;
Cause of Death
;
Chromosomes, Human, Pair 17*
;
Female
;
Fibroadenoma
;
Gene Amplification*
;
Gene Expression
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Humans
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Lymph Nodes
;
Mammaplasty
;
Monosomy
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Neoplasm Metastasis
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Paraffin
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Tetrasomy
;
Trisomy
5.Normal anthropometric values and standardized templates of Korean face and head.
Joon Hyun CHO ; Ki Hwan HAN ; Jin Sung KANG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(5):995-1005
No abstract available.
Head*
8.A study on CT stage of cervix cancer
Kyung Hi LEE ; Ki Hwan KIM ; Ki Hyeun CHANG ; Seong Hwan HA ; Charn Il PARK ; Man Chung HAN
Journal of the Korean Radiological Society 1982;18(4):850-858
CT findings and comparison between clinical and CT staging were reviewed in 45 consecutive patients withbiopsy proven carcinoma of the cervix. CT was done for staging of primary untreted cercial cancer in 36 patientsand for diagnosis of recurrent cervical cancer or follow-up study 14 times in 9 patients . The results are asfollows; 1. As comparing with clinical staging in 36 cases, CT agreed with clinical stage in 19 cases (52.8%),upstaged in 10 cases(27.8%) and downstaged inn 7 cases (19.4%). 2. The main upstaged CT findings are detection ofunsuspected bladder or rectal invasion and paraaortic lymph node metastasis. Inadequate delineation ofintravaginal tumor was the leading causes of understage of CT than clinical one. 3. CT detected all 10 cases ofthe hydronephrosis shown by IVP and detected unsuspected bladder invasion in 3 cases. 4. CT was valuable in thediagnosis of recurrent tumor and follow-up study after treatment. 5. CT offeres distinct advantages over clinicalstaging and can be integrated into the present FIGO classification of uterine cervix carcinoma. CT can served asan initial radiological staging work-up of primary of recurrent cervical carcinoma.
Cervix Uteri
;
Chungcheongnam-do
;
Classification
;
Diagnosis
;
Female
;
Follow-Up Studies
;
Humans
;
Hydronephrosis
;
Lymph Nodes
;
Neoplasm Metastasis
;
Urinary Bladder
;
Uterine Cervical Neoplasms
9.The Age-Related Anthropometric Analysis of Eyelids and Orbits in Koreans.
Chul Hong SONG ; Ki Young AHN ; Dong Cil HAN ; Dae Hwan PARK
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1999;26(6):1131-1137
The extensive knowledge of accurate anatomical morphology and acceptable proportion of the eyelid and orbit should be needed for plastic surgeons. The normal morphological and functional values of eyelids and orbits are variable according to races, sex and ages, and there are a few articles concerning them in Korea yet. The author measured eigt items of morphological and functional values of eyelids in Koreans and statistically analyzed them in 498 individuals including 234 males and 264 females. We divided them into nine age-related groups and measured the values. Especially, we subdivided 10 to 19 year-old group into three subgroup concretely because most of the values in the 10 to 19 year-old group reach the peak level of growth. The mean values in adults were recorded as follows: The horizontal dimension of the palpebral fissure was 27.0 +/- 1.8 mm in males and 26.8 +/- 1,7 mm in females and the vertical dimension of the palpebral fissure was 8.0 +/- 1.0 mm in female. The slant of the palpebral fissure was 7.9 +/- 2.4 degrees in males and 8.8 +/- 2.3 degrees in females and the height of the opened upper eyelid was 12.4 +/- 2.4 mm in males and 12.0 +/- 1.9 mm in females. The height of double fold in closed eye was 6.6 mm in males and 6.5 mm in femals and the intercanthal distance was 38.4 +/- 3.0 mm in males and 38.2 +/- 2.8 mm in females. The interpupillary distance was 64.6 +/- 2.9 mm in males and 63.6 +/- 2.9 mm in females. A double fold was seen in 36.1% of Korean. The average height of the double fold in closed eye was about 6.5 mm. The epicanthus present in 58.6% of Korean eyes and the most commom type was epicantus tarsalis. The growth of eyelids reached the peak level at teenager in a great portion. After the peak level, the changing pattern of eyelids could be divided into 3 groups; the first one was increasing more, the second was stationary, and the third was decreasing gradually. The peak levle of growth reached at 10 to 13-year-old in the vertical dimension of the palpebral fissure, at 14 to 16-year-old in the intercanthal distance, at 17 to 19-year-old in the horizontal dimension of the palpebral fissure.
Adolescent
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Adult
;
Continental Population Groups
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Eyelids*
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Female
;
Humans
;
Korea
;
Male
;
Orbit*
;
Vertical Dimension
;
Young Adult
10.Observation of Microscopic Examination and Bacterial Culture of the Prostatic Secretion in Chronic Prostatitis.
Korean Journal of Urology 1983;24(5):779-782
An observation was performed for the microscopic examination and bacterial culture of the prostatic secretion on 67 cases of the chronic prostatitis and 41 cases of normal adult in the Department of urology, Han-Il Hospital from February 1982 to January 1983. The following results were obtained: 1. In 41 cases of normal adults who performed prostatic secretion culture, 19 cases (46.3%) were positive culture and the remained 22 cases (53.7%) were negative culture. 2. In 19 cases of normal adults who were positive culture, there were Staphylococcus epidermidis in 15 cases (79.0%), alpha streptococcus in 2 cases (10.5%) and diphtheroid in 2 cases (10.5%)and diphtheroid in 2cases (10.5%). 3. In cultures of prostatic secretion in 67 cases of chronic prostatitis, 10 cases(14.9%) were no growth and 57 cases (85.1%) revealed bacterial growth. 4. In 57 cases of positive cultures in chronic prostatitis, the isolated organisms revealed 27 cases (47.1%) Of Staphylococcus epidermidis, 13 cases (22.8%) of E. Coli, 12 cases (21.1%) of alpha streptococcus, 2 cases (3.5%) of diphtheroid, 2 cases (3.5%) of enterococcus and 1 case (1.7%) of Klebsiella. The pathogenic bacteria among these were 16 cases (28.0%). 5. In the microscopic examination and culture of the prostatic secretion in chronic prostatitis, microorganisms were cultured in 17 cases (73.9%) among 23 cases of 11-20 WBCs/HPF, in 16 cases (84.2%) among-19 cases of 21-50 WBCs/HPF and in 24 cases (96.0%) among 25 cases of more than 51 WBCs/HPF.
Adult
;
Bacteria
;
Enterococcus
;
Humans
;
Klebsiella
;
Prostatitis*
;
Staphylococcus epidermidis
;
Streptococcus
;
Urology