1.The Two Cases of Children with Buckwheat Allergy Confirmed by Oral Challenge Test.
Journal of the Korean Pediatric Society 1985;28(6):604-609
No abstract available.
Child*
;
Fagopyrum*
;
Humans
;
Hypersensitivity*
2.The abnormalities of immune function ib schizophrenics(III).
Oh Young KWON ; Ki Seok HAN ; Young Cho CHUNG
Journal of Korean Neuropsychiatric Association 1993;32(6):998-1005
No abstract available.
3.The Hemodynamics and Electrocardiogram in Isolated Ventricular Septal Defect.
Kwang Man KIM ; Ki Young SONG ; Sang Kwon LEE ; Tae Chan KWON ; Chin Moo KANG
Journal of the Korean Pediatric Society 1989;32(8):1098-1105
No abstract available.
Electrocardiography*
;
Heart Septal Defects, Ventricular*
;
Hemodynamics*
4.Clinical Usefulness of Transesophageal Echocardiography for Detection of LA Thrombi and Significance of Left Atrial Spontaneous Contrast.
Kee Sik KIM ; Young Sung SONG ; Yoon Nyun KIM ; Ki Young KWON ; Kwon Bae KIM ; Sae Young CHOI
Korean Circulation Journal 1992;22(4):599-606
BACKGROUND: To evaluate the efficacy of transesophageal echocardiography(TEE) to detect left atrial thrombi(LAT) and to investigate the clinical and echocardiography parameters which related with LAT. METHOD: We performed TEE and TTE simultaneously to 98 consecutive patients who had native mital valve disease or mital prosthesis as usual method. We examined the presence and location of LAT and spontaneous contrast(SC) in TEE and measured left atrial dimension(LAD), ejection fraction(EF), mital valve area(MVA) in TTE. Cardiac rhythm, history of anticoagulation and systemic embolization were also reviewed. We compared such parameters in LAT positive/negative groups and SC positive/negative groups. RESULTS: 1) In TEE, we detected 26 cases of LAT, among them seventeen cases : left atrial appendage(LAA) thrombi, 3 cases : combined LA and LAA thrombi, 6 cases : LA thrombi. In TTE, six cases showed LAT but we couldn't detect LAA thrombi. The difference between two methods was statistically significant(p<0.05). 2) LAT positive group showed larger LAD, lower EF, and higher prevalence of AF, systemic embolization, and LAT than negative groups(p<0.01). 3) SC positive group showed larger LAD, lower EF, higher prevalence of AF, systemic embolization LAT than SC negative groups(p<0.05). 4) In multiple discriminant analysis, the history of systemic embolization was most important factor which can suspect LAT(Wilk's Lambda:0.77152. p<0.0001). SC, EF, presence of AF, LAD, anticoagulation therapy. MVR were also statistically valuable factors in order. The hit ratio of this analysis was 86.84%. CONCLUSION: We can suggest that TEE is very useful method to detect LAT than TTE, and the spontaneous contrast was very important factor which can suggest LAT and systemic embolization in mitral valve disease.
Echocardiography
;
Echocardiography, Transesophageal*
;
Humans
;
Mitral Valve
;
Prevalence
;
Prostheses and Implants
5.A immunohistochemical study of localization of calcitonin gene related peptide in the rats cochlear nucleus and superior olivary complex.
Young Ki KIM ; Seong Woan KIM ; Jin Young YANG ; Ki Hwan HONG ; Sam Hyun KWON ; Yong Joo YOON
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(4):702-708
No abstract available.
Animals
;
Calcitonin Gene-Related Peptide*
;
Calcitonin*
;
Cochlear Nucleus*
;
Rats*
6.A Study on Methacholine Challenge Test in Asthmatic Children.
Yong Gab KWON ; Ki Young LEE ; In Hee PARK ; Han Young LEE
Journal of the Korean Pediatric Society 1985;28(11):1073-1081
No abstract available.
Child*
;
Humans
;
Methacholine Chloride*
8.Anticancer Effect of Arsenic Trioxide in Acute Promyelocytic Leukemia.
Ki Young SONG ; Jin Hye PARK ; Yoon Jung CHO ; Won Ki BAEK ; Ki Young KWON ; Heung Sik KIM ; Chin Moo KANG
Journal of the Korean Pediatric Society 2000;43(3):327-334
PURPOSE: Acute promyelocytic leukemia (APL or AML, M3) represents an unique model for cancer research in terms of biological and clinical features. Since 1988, it has been widely confirmed that all-trans retinoic acid (ATRA) can induce complete clinical remission in over 85% of APL patients by a differentiation process, with PML-RARalpha protein possibly being the direct target of ATRA. However, ATRA treatment has two clinical limitations, namely, retinoic acid syndrome and retinoic resistance. Recently, it has been shown that arsenic trioxide used in some traditional Chinese remedy is very effective in retinoic resistant APL treatment. We tried to observe arsenic effect on cell lines and APL patient cells. MEHTODS: We investigated arsenic trioxide-induced apoptosis on APL, HL60, K562, KPH1 cell lines through MTT assay, DNA fragmentation assay and morphologic features. RESULTS: In MTT assay, cell survival rate decreased as the concentration of arsenic trioxide increased. In DNA fragmentation assay with HL60 cell line, DNA fragmentation was more frequent in high concentrations of arsenic trioxide than in low concentrations. During arsenic trioxide treatment, the morphologic change in bone marrow cells of APL patient, included nuclear differentiation and dark cytoplasmic granule during arsenic trioxide treatment. Serum arsenic reached peak level at 4hr after injection. We experienced a case of a 9-year-old male with APL who had relapsed after cessation of retinoic acid treatment. The patient successfully achieved remission following arsenic trioxide treatment without bone marrow depression and exacerbating bleeding diathesis. CONCLUSION: Arsenic trioxide can be used effectively to treat APL patients by inducing apoptosis and partial differentiation in tumor cells. The precise cellular and molecular mechanisms of its therapeutic effects remain to be determined.
Apoptosis
;
Arsenic*
;
Asian Continental Ancestry Group
;
Bone Marrow
;
Bone Marrow Cells
;
Cell Line
;
Cell Survival
;
Child
;
Cytoplasmic Granules
;
Depression
;
Disease Susceptibility
;
DNA Fragmentation
;
Hemorrhage
;
HL-60 Cells
;
Humans
;
Leukemia, Promyelocytic, Acute*
;
Male
;
Tretinoin
9.A clinical survey of cesarean hysterectomy.
Myung Sik JOO ; Chul PARK ; Ki Hak LEE ; Sang Kyung KIM ; Young Ho RHA ; Ki Sang KWON
Korean Journal of Obstetrics and Gynecology 1993;36(7):2652-2659
No abstract available.
Hysterectomy*
10.Value of Tip/Base Rgidity Activity Unit on Interpretation of Nocturnal Penile Tumescence & Rigidity Monitoring.
Won Jae YANG ; Sang Kwon BYON ; Woo Young KI ; Heon Gwan LIM ; Woong Hee LEE ; Hyung Ki CHOI
Korean Journal of Urology 2000;41(11):1389-1393
No abstract available.
Male
;
Penile Erection*