No abstract available.
Humans ; Hyperbilirubinemia* ; Infant, Newborn*

We present a case of multiple cutaneous leiomyoma in a 45 year old woman. About 20 years ago, multiple skin colored papules developed on right cheek and man4ibular area. About 10 years after the onset of the disease a uterine myoma developed which wae tree,ted by total hysterectomy. The skin lesions were gradually increasing in number and size, Some larger nodular lesions changed to brown in color and became painful after cold exposure. The histopathologic finding showed typical leiomyoma arieing from arrector pilorum muscle.
Cheek ; Female ; Humans ; Hysterectomy ; Leiomyoma* ; Middle Aged ; Skin

No abstract available.
Aneurysm* ; Cerebral Infarction* ; Foramen Ovale, Patent*

No abstract available.
Gallium* ; Neoplasm, Residual* ; Wounds and Injuries*

Retroperitoneal foregut duplication cyst is an extremely rare congenital malformation. Pathologically, this lesion contains both gastric mucosa and respiratory type mucosa; radiologically, it is often challenging to differentiate it from the other cystic neoplasms that present a similar appearance. We report here on a case of retroperitoneal foregut duplication cyst that was lined by both gastric and pseudostratified ciliated columnar epithelium, and it was also accompanied by a pancreatic pseudocyst. Initially, it presented with peripancreatic and intrapancreatic cystic masses in an asymptomatic 30-year-old man, and this man has since undergone surgical resection.
Adult ; Epithelium ; Gastric Mucosa ; Humans ; Mucous Membrane ; Pancreatic Pseudocyst

OBJECTIVES: Recently, it was suggested that apoptosis may be a basic mechanism of follicular atretic process. If the POF(premature ovarian failure) results from an acceleration of the process of atresia of the oocytes causing premature deletion of stored oocytes, POF may be a good model for the apoptosis. Our objective is to determine the relation between the POF and apoptosis. METHODS: We performed laparoscopic ovarian biopsy in 17 patients with POF. We evaluated the ovaries from a patient with POF by conventional H-E stining and immunohistochemical staining for apoptosis related protein(bcl-2, bax, fas and fas-L). RESULTS: Atretic cystic follicles were seen 4 out of 17 patients, and corpora albicans indicating past ovulation were seen 9 out of 17 patients. Primordial follicles were seen in 3 out of 17 patients, however developing follicles were not seen in all patients. Immunohistochemical analysis revealed that Bax was expressed in the lining cells of the atretic cystic follicle and primordial follicle and mesothelial cells lining the surface of the ovary. Fas and Fas-L were expressed on the lining pregranulosa cells and primary oocyte of the primordial follicle in the ovary of the patient with premature ovarian failure. Bax were also expressed on the lining pregranulosa cell and oocyte of the premature ovarian failure. Bcl-2 was expressed in the lining cells of primordial follicles of the patients with POF. CONCLUSION: Apoptosis may be a basic mechanism of POF. Bax, fas and fas-L may play a role causing premature follicular depletion.
Acceleration ; Apoptosis* ; Biopsy ; Female ; Humans ; Oocytes ; Ovary* ; Ovulation ; Primary Ovarian Insufficiency*

PURPOSE: Intrahepatic duct stone (IHD) disease, especially bilateral lesion, is difficult to management for complete cure. The purpose of this study is to analyze the clinical manifestations and treatment outcomes and is to consider adequate strategy of treatment between unilateral and bilateral IHD stones. METHODS: From October 1993 to July 2004, 218 patients with IHD stone were performed by surgical management at Ewha Womans University Mokdong Hospital. The medical records of these patients were reviewed retrospectively. We classified into two groups, such as unilateral group (U group) and bilateral group (B group), and compared two groups for clinical manifestations and outcomes. RESULTS: Of the 218 IHD stone patients, 188 cases underwent conventional open surgery, 20 cases underwent laparoscopic surgery, and 10 cases underwent laparoscopic assisted surgery. U group and B group was composed 162 and 56 cases, respectively. IHD stones were more common in left lobe of liver than right lobe in U group (P<0.001). IHD stricture were more common in U group (P=0.048). On the other hand, remnant stones were more common in B group (P<0.001). There was no statistical significance for postoperative complication and method of operation include liver resection between two groups. CONCLUSION: We presume that the pathogenesis may be different between unilateral and bilateral IHD stone. To cure or reduce the remnant stone rate, more aggressive treatment such as liver resection should be also considered in the patients with bilateral as well as unilateral IHD stone because of no difference of complication rate of two groups.
Constriction, Pathologic ; Female ; Hand ; Humans ; Laparoscopy ; Liver ; Medical Records ; Postoperative Complications ; Retrospective Studies

OBJECTIVE: To investigate possible relationship between uterine leiomyoma and serum leptin levels, we compared serum leptin levels between women with uterine leiomyoma and women without leiomyoma, and then investigate the effects of hysterectomy on serum leptin levels. METHODS: Serum leptin levels were measured before (day-1) and after (day+5) surgery for 32 women with uterine leiomyoma and were measured when they visit our health promotion center for 32 normal women. We compared serum leptin levels between two groups, and then we analyzed perioperative changes of serum leptin levels in women with uterine leiomyoma. Pearson correlation test was performed between pre-/postoperative leptin ratio and resected uterine weight to investigate whether the changes of serum leptin levels are directly related with resection of leiomyoma. RESULTS: In women with uterine leiomyoma, serum leptin levels were lower compared with normal group (7.41+/-4.31 ng/mL vs. 17.56+/-8.65 ng/mL) (P<0.05). Postoperative serum leptin levels were decresed than preoperative serum leptin levels (6.07+/-2.98 ng/mL vs. 7.41+/-4.31 ng/mL) (P<0.05). Pearson correlation coefficient between pre-/postoperative leptin ratio and resected uterine weight showed no statistical significance. CONCLUSION: Serum leptin levels were lower in women with uterine leiomyoma. And serum leptin levels were more decreased after hysterectomy. There were significant postoperative decrease in serum leptin levels but the result between pre-/postoperative leptin ratio and resected uterine weight revealed no direct correlation. It seems that lower serum leptin levels maybe due to postoperative stress and neuroendocrinological response rather than myoma itself. In conclusion, further investigation is needed for clinical use of serum leptin levels as a serum marker after conservative treatment of uterine leiomyoma.
Biomarkers ; Female ; Health Promotion ; Humans ; Hysterectomy ; Leiomyoma* ; Leptin* ; Myoma

The definition of volvulus is an axial twist of a portion of the gastrointestinal tract along its mesentery. The involved bowel is obstructed partially or completely with a variable degree of arterial and venous occlusion. The colon is the most common site for volvulus. The splenic flexure is the least common site of colonic volvulus. We experienced a case of the volvulus of the splenic flexure. It will be the 30th case of the volvulus involving the splenic flexure in the English literature, to our knowledge. A 30-year-old woman was admitted due to abdominal pain and distention with vomiting. An emergency barium study revealed characteristic "bird beak" sign. Surgery was performed resecting the involved colon of splenic flexure. The result was excellent.
Adult ; Barium Sulfate/diagnostic use ; Case Report ; Colonic Diseases/*radiography ; Female ; Human ; Intestinal Obstruction/*radiography

No abstract available.
Pregnancy* ; Ultrasonography*