No abstract available.
Goiter*

No abstract available.
Humans ; Infant* ; Infant, Low Birth Weight* ; Infant, Newborn ; Jaundice* ; Phototherapy*

Cerebral aspergillosis is a rare condition that affects primarily the immunocompromised host. Most of cerebral aspergillosis is developed by hematogenous dissemination from extracranial foci, but aspergillosis of sino-nasal origin rarely affects the CNS. In case 1, wel symptom of tumor recurrence was unilateral numbness of the chin. A 65-year-old male was admitted because of paresthesia around the left chin and left lower lip. Neurologic examination revealed hypesthesia on the left side of chin, lower lip and buccal mucous mem-brane. Bone scan (Tc-99m MDP) showed focal hot uptakes on the left mandible and left first rib. Brain CT with bone window setting showed a focal osteolytic lesion in the bone marrow of the left mandibular canal without destruction of bone cortex. Both coronal T1 weighted image and axial T2 weighted image showed focal low signal intensities on the left ramus. The pathophysiologic mechanism could be understood by identification of the pathologic focus.
Aged ; Aspergillosis* ; Bone Marrow ; Brain ; Chin ; Humans ; Hypesthesia ; Immunocompromised Host ; Lip ; Male ; Mandible ; Neurologic Examination ; Paresthesia ; Recurrence ; Ribs

We have reviewed the 503 cases of benign skin tumors which were confirmed by histopathological study from January 1977 to July 1987 in the Dermatologic Department of Kyungpook National University Hospital. The result were summarized as follows . l. Among the total of 26,690 dermatologic out patients, 503 cases(1.9%) were diagnosed as having benign skin tumors. The number of benign skin tumors has shown a noticeable increase in the last several years. 2. The tumors were found mainly in ages ranging from the 2nd to 5th decade, most commonly in the 3rd decade(124 cases, 24.7%). 3. Aceording to Lever's elasaification, the tumors were divided into the following 7 groupa . tumors and cyets of the epidermis(35.2%), melanocytic tumors(16.5%), tumors of vaecular tissues(13.3%), tumora of epidermal appendages(11.1%), tumors of fibrous tissue(8.9%), tumors of neura.l tiasue(7.6%) and tumors of fatty, muscular and osseous tiseue(7.4%) in decreasing orders. 4. The 14 common tumors in order of frequency were as follows epidermal cyst (17.l% ),:melanocytic nevus(16.5%), neurofibroma(7.6%), congenital hemangioma(6.4%), nevus sebaceous(6.0%), lipoma(5.2%),seborrheic keratosis(4,8%), linear epidermal nevus(4.6%), steatocystoma mutiplex(2.8%), dermatofibroma(2.6%), hypertrophic scar and keloid.(2.6%), granuloma pyogenicum(2.4% ), keratoacanthoma(2.0%) and syringoma (2,0%). 5. The predilection sites of seborrheic keratosis, keratoacanthoma, syringoma and melanocytic nevus were the face, linear epidermal nevus, dermatofibroma and granuloma pyogenicum were located on the extremities. 6. The duration of tumors from the presumed time of onset to the first visit was within 1 year for epidermal cyst, keratoacanthoma and granuloma pyogenicum, over 10 years for nevus sebaceous, congenital emangioma and neurofibroma. 7. Diagnostic accuracy was higher in melanocytic nevus, congential hemangioma, nevus sebaceous and neurofibroma and lower in steatocystoma multiplex, dermatofibroma, keratoacanthoma, lipoma and epidermal cyst.
Cicatrix, Hypertrophic ; Epidermal Cyst ; Extremities ; Granuloma ; Granuloma, Pyogenic ; Gyeongsangbuk-do ; Hemangioma ; Histiocytoma, Benign Fibrous ; Humans ; Keratoacanthoma ; Keratosis, Seborrheic ; Lipoma ; Neurofibroma ; Nevus ; Nevus, Pigmented ; Outpatients ; Skin* ; Steatocystoma Multiplex ; Syringoma

BACKGROUND: Hypertension is the major risk factor for cardiovascular disease. The increased left ventricular mass has been recognized as an independent predictor of morbidity and mortality in hypertensive patients. The assessment of the regression of left ventricular(LV) mass after antihypertensive therapy offers prognostic information. 2D echocardiography has proved a sensitive tool for the detection of the change of LV mass. METHOD: LV mass and LV mass index were measured by area-length method of 2D echocardiography in 26 hypertensive patients and 10 normal control to evaluate the effect of betablocker(group I, n=16) and angiotensin converting enzyme(ACE) inhibitor(group II, n=10) on the regression of LV mass. RESULT: There was a significant increase of LV mass and LV mass index in the hypertensive patients(199.0+/-37.7gm, 119.2+/-21.2gm/m2) compaired to the control(129.7+/-11.7gm, 87.4+/-8.8gm/m2)(p<0.01, p<0.01). After 13.1 week treatment, LV mass was significantly decreased in group I(200.9+/-35.3gm vs 164.7+/-25.4gm)(p<0.01) and group II(195.9+/-43.3gm vs 152.4+/-27.1gm)(p<0.01). The LV mass index was also significantly decreased in group I(120.3+/-20.7gm/m2 vs 98.8+/-15.5gm/m2)(p<0.01) and group II(117.5+/-22.9gm/m2 vs 91.5+/-13.6gm/m2)(p<0.01). CONCLUSION: This results showed that LV mass can be reduced in hypertensive patients who receive beta blocker and ACE inhibitor. The effect of antihypertensive therapy on LV mass should be considered in treatment of the hypertensive patients who had hypertrophied LV.
Angiotensins ; Cardiovascular Diseases ; Echocardiography ; Humans ; Hypertension ; Mortality ; Risk Factors

No abstract available.
Congenital Abnormalities* ; Ilizarov Technique* ; Upper Extremity*

In general, the operative treatment of the brachymetatarsia is the lengthening of the affected metatarsal bone due to the cosmetic problem rather than the functional one. We experienced 22 year-old female bilateral congenital foot deformities such as hallux varus and 1,4th brachymetatarsia treated with reverse Scarf osteotomy on the hallux varus and massive axial metatarsal shortening Weil osteotomy on the 2,3,5th metatarsals which could reconstruct the normal metatarsal parabola.
Callosities ; Cosmetics ; Female ; Foot Deformities, Congenital ; Hallux ; Hallux Varus ; Humans ; Metatarsal Bones ; Osteotomy

No abstract available.
Gaucher Disease* ; Humans ; Twins, Monozygotic*

Acute thyroiditis is a rare disease because of the sufficient supply of blood vessels and lymphatics in thyroid tissue, the high concentration of iodide in the thyroid tissue and the nearly completely isolated structure of the thyroid gland from the surrounding tissue via its capsule. The most common route of infection is from a pyriform sinus fistula and then the inflammation spreads from the sinus to the perithyroidal space. Computed tomography (CT) and magnetic resonance imaging (MRI) can show a low echogenic mass encircling thyroid gland and swelling of the perithyroidal tissue in acute suppurative thyroiditis. We experienced a case of acute perithyroiditis with thyrotoxicosis that developed in a 13-year old boy and he was diagnosed by the CT findings. The patient had complained of a low graded fever and neck swelling. The laboratory diagnosis and clinical course was like that of subacute thyroiditis, but the CT finding showed a show low echogenic mass encircling the thyroid glands and swelling of the perithyroidal tissue. Therefore, we diagnosed this patient with acute perithyroiditis. After treatment with antibiotics, he displayed clinical improvement and was discharged.
Adolescent ; Anti-Bacterial Agents ; Blood Vessels ; Clinical Laboratory Techniques ; Fever ; Fistula ; Humans ; Inflammation ; Magnetic Resonance Imaging ; Male ; Neck ; Pyriform Sinus ; Rare Diseases ; Thyroid Gland ; Thyroiditis ; Thyroiditis, Subacute ; Thyroiditis, Suppurative ; Thyrotoxicosis*

Tolvaptan, a non-peptide arginine vasopressin V2 receptor antagonist, is a newly developed drug to reduce kidney volume and preserve kidney function in autosomal dominant polycystic kidney disease (ADPKD) patients. We aimed to evaluate the descriptive characteristics of patients according to the use of tolvaptan. Also, we tried to find the efficacy of tolvaptan on kidney volume and kidney function. We included patients with ADPKD who visited a tertiary hospital in South Korea during Sep. 2018 and Apr. 2022. The data was acquired from the Electric Medical Records system. A total of 64 patients were included in the study, and there were 33 (51.6%) patients taking tolvaptan during follow-up periods. During 17.8 ± 13.1 months of follow-up periods, estimated glomerular filtration rate (eGFR) changes were 89.4% compared to the baseline eGFR. Although the latest eGFR was lower in patients with tolvaptan (55.9 ± 24.7 mL/min/1.73 m2) than without tolvaptan (68.4 ± 35.1 mL/min/1.73 m2), there was no statistical significance (p = 0.108). We found that the mean change of height-adjusted total kidney volume (HtTKV) was -2.7% based on the baseline HtTKV in patients taking tolvaptan for more than 1-year. Although there was no statistical significance, the mean change of HtTKV was the highest in patients with 1E of Mayo classification (-4.3%). To anticipate the solid data on the efficacy of tolvaptan in the Asian population, more aggressive efforts are needed to search for suitable patients accompanied by appropriate monitoring over a more extended period.