1.Drug Consumption and Nutritional Status of the Elderly in Chung-buk Area: II. Nutritional Status of Urban and Rural Elderly.
Kyung Hee HAN ; dong Yean PARK ; Ki Nam KIM
Korean Journal of Community Nutrition 1998;3(2):228-244
The nutritional status of 362 elderly men and women in Chung-bud area was evaluated in terms of their nutrient intakes, biochemical and anthrophometric measurements by interviews with questionnaires from August to October 1996. Mean intake of all nutrients except ascorbic acid did not meet the RDA for this sample. Protein, vit A, reboflavin, calcium were the most likely to be deficient on the basis of propotions of elderly consuming less than 75% of the RDA. The subjects nutrient intake was significantly affected by gender, marital status, number of family, family composition, educational level, pocket money, and region. Men in rural areas and women over 75 in urban areas were the most vulnerable groups with nutritional deficiency. According to serum biochemical indices, mean level of cholesterol, triglycerides, LDL, total protein, albumin and iron belonged to normal range but mean level of HDL showed below the normal range. More elderly men and women in urban areas showed a higher percentage of abormal level of cholesterol, triglycerides, LDL and HDL than those in rural areas. More elderly men and women in rural areas had abnormal levels of RBC, Hematocrit and hemoglobin compared to those in urban areas. Mean height and weight of elderly men was 161.4cm and 56.2Kg, respectively and 149.1cm and 50.5kg for women. The elderly in rural areas were taller than those in urban areas but had less weight, MAC, TSF, MAMC. Mean BMI of this sample belonged to normal range. However, the elderly in rural areas had a higher rate of underweight and lower for overweight than those in urban areas. The elderly in urban areas had higher blood pressure than those in rural areas.
Aged*
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Ascorbic Acid
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Blood Pressure
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Calcium
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Cholesterol
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Female
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Hematocrit
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Humans
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Iron
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Male
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Malnutrition
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Marital Status
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Nutritional Status*
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Overweight
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Reference Values
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Thinness
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Triglycerides
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Surveys and Questionnaires
2.Finding and Characterization of Viral Nonstructural Small Protein in Prospect Hill Virus Infected Cell.
Ki Yean NAM ; Dong Hoon CHUNG ; Jae Won CHOI ; Youn Seong LEE ; Pyung Woo LEE
Journal of the Korean Society of Virology 1999;29(4):221-233
No abstract available.
3.Drug Consumption and Nutritional Status of the Elderly in Chung-Buk Area: I. Diseades and Drug Consumption.
Kyung Hee HAN ; Ki Nam KIM ; Dong Yean PARK
Korean Journal of Community Nutrition 1998;3(1):76-93
Three hundred sixty-two(male 131, female 231) elderly aged over 65 in Chungbuk area were interviewed to determine the disease states and drug usage patterns. The prebalence of disease was 78% and women reported more chronic diseases(83%) than men(71%). Elderly who live with spouse and have an occupation have a lower rate of disease. Average number of diseases of the elderly was 1.8+/-1.1, and women(2.1+/-1.3) have significantly higher average number of diseases than that of men(1.4+/-0.7). Also the elderly in urban areas(2.1+/-1.4) have significantly higher number of diseases than that of the elderly in rural areas(1.6+/-0.9). Arthritis, hypertension, cardiovascular and gastric diseases were the most frequently listed chronic diseases in order for both men and women. Anemia and fracture of bone were relatively higher in women than in men. Particularly, the arthritis of the urban elderly have a rate of 1.5 times higher than that of the rural elderly. Fifty-two percent of the elderly were currently using drugs ; among drug users 71.2% used prescription drugs and 20.5% used nonprescription drugs. The average number taken per person was 2.1+/-1.4 and there was no sex or age difference. However, the elderly in rural areas (2.7+/-1.7) consumed a significantly higher number of drugs than those in urban areas(1.7+/-0.7). The average number of prescription drugs taken was 2.0+/-1.4 while the average of nonprescription drugs taken was 1.3+/-0.6. Analgesics and antihypertensive drugs were most commonly used. Vitamin and analgesics were the most frequently used self-prescribed drugs. It was noted that potential adverse drug interaction by concominant drug consumption for arthritis and antihypensive drug, abuse of digestants and antiacid without treatment of the underlying disease, and misuse of quick-acting bowel medications were problematic for the elderly. In addition drugs used for the elderly have some adverse effect on the digestive system. The types and composition of drugs used by the elderly were identified and presented. Medication compliance was poor and 13.5% reported adverse reactions such as edema, heartburn, nausea, and difficulty with eating. Seventeen percent of the elderly obtained drugs arranged by those other than medical staff. Also, even among those elderly who obtained drugs prescribed by a doctor, 69.1% of subjects had not receive instruction about potential adverse reactions. These results suggest that nutritional problems related to drug usage might exist and so dietitians, either individually or as members of health teams, need to have a better understanding of drug-nutrient interaction and closer supervision, and drug information/education service should therefore be provided to prevent or minimize adverse drug reaction in elderly users of medication.
Aged*
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Analgesics
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Anemia
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Antihypertensive Agents
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Arthritis
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Chronic Disease
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Chungcheongbuk-do
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Digestive System
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Drug Interactions
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Drug Users
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Drug-Related Side Effects and Adverse Reactions
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Eating
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Edema
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Female
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Gastrointestinal Agents
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Heartburn
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Humans
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Hypertension
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Male
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Medical Staff
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Medication Adherence
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Nausea
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Nonprescription Drugs
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Nutritional Status*
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Nutritionists
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Occupations
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Organization and Administration
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Prescription Drugs
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Spouses
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Stomach Diseases
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Vitamins
4.Drug Use and Nutritional status of the Elderly in chungbuk area: IV. effects of drug Use & Health-Related Habits (Alcohol drinking, cigarette smoking & exercise) on Nutritional status.
Kyung Hee HAN ; Ki Nam KIM ; Dong Yean PARK
Korean Journal of Community Nutrition 1998;3(3):397-409
The purposes of this study were to investigate the effects of drug use & the health-related habits(alcohol drinking, smoking and exercise) on the nutritional status of elderly. subjects were 362 free-living elderly aged over 65(male 131, female 231) in Chungbuk area. Interviews with questionaire on drug use, health-related habits, and nutrient intakes, anthropometric measurement and biochemical blood test were carried out from August to October in 1996. Energy intakes of the males who used drug were lower than those of males who did not use any drug, while energy intakes of the females who used drug were higher than those of females who did not. In biochemical indices, LDL-cholesterol level of the males who used drug was higher than that of males who did not have drug. serum triglycerides, VLDL-cholesterol and obesity degree(BMI & TS) of the females who used drug were higher than those of females who did not have drug. Alcohol drinking, smoking and exercise habits of the elderly who used drug had little effects on the nutrient intakes while those habits had considerable effects on biochemical indices and obesity degree. Among drug users, male drinkers showed higher triglycerides & HDL-cholesterol level, and female drinkers showed higher triglycerides and lower total cholesterol and LDL-cholesterol level, compared to non drinkers. Among female drug users, smokers showed lower body mass index(BMI) compared to non smokers. Males and females who had both drinking and smoking habits showed higher serum triglycerides and VLDL-cholesterol level. Especially females who had both drinking and smoking habits showed lower BMI & Tricep skinfold thickness compared to those who had netiher drinking nor smoking habits.
Aged*
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Alcohol Drinking
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Cholesterol
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Chungcheongbuk-do*
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Drinking*
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Drug Users
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Female
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Hematologic Tests
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Humans
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Male
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Nutritional Status*
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Obesity
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Skinfold Thickness
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Smoke
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Smoking*
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Tobacco Products*
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Triglycerides
5.Drug Consumption and Nutritional Status of the Elderly in Chung-buk Area: III. Psychological Effect on Drug Consumption and Nutritional Status.
Dong Yean PARK ; Kyung Hee HANM ; Ki Nam KIM
Korean Journal of Community Nutrition 1998;3(2):245-260
The influences of depression and health anxieth on the elderly's drug use and nutritional status were evaluated by interviews with questionaire from August to October in 1996. One hundred and thirty-one male and 231 female elderly in Chung-buk area were the sample for this study. Men's depression score was 22.3 and 25.2 for women, respectively out of 27. Women showed a significantly higher score for depression and health anxiety than men. Gender, age, marital status, number of family, education, income, medical insurance, and mobility and region significantly affected the health anxiety score. The higher depression score the elderly had, the more frequently they took drugs. Conversely. the higher depression score the elderly had, the less frequently they took nutritional supplements. For women, the higher depression score the elderly had, the more they smoked. More depressed elderly showed a significantly smaller BMI compared to the less depressed ones. A negative correlationship existed between the depression score and the elderly's nutrient intakes, especially energy intake which showed a significant negative correlation. There were no significant differences between health anxiety score and nutrient intakes of men. Women who had a higher health anxiety score consumed more energy significantly. The depression score did not affect the elderly's blood biochemical indices. Women who had a low health anxiety score showed a significantly higher HDL-C level.
Aged*
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Anxiety
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Depression
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Education
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Energy Intake
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Female
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Humans
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Insurance
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Male
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Marital Status
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Nutritional Status*
;
Smoke
6.Mycobacterial Infection after Intravesical Bacillus Calmette-Guerin Treatment for Bladder Cancer: A Case Report.
Chang Hun PARK ; Mi Ae JANG ; Yoon Hee AHN ; Yu Yean HWANG ; Chang Seok KI ; Nam Yong LEE
The Korean Journal of Laboratory Medicine 2011;31(3):197-200
Bacillus Calmette-Guerin (BCG) has been traditionally used as a vaccine against tuberculosis. Further, intravesical administration of BCG has been shown to be effective in treating bladder cancer. Although BCG contains a live attenuated strain of Mycobacterium bovis, complications such as M. bovis BCG infection caused by BCG administration are extremely rare. Here, we report a case of BCG infection occurring after intravesical BCG therapy. A 67-yr-old man presented with azotemia and weight loss. He had been diagnosed with bladder cancer 4 yr back, and had undergone transurethral resection of the bladder tumor and intravesical BCG (Tice strain) therapy at that time. An acid-fast bacterial strain was isolated from his urine sample. We did not detect Mycobacterium tuberculosis protein 64 (MPT-64) antigen in the isolates obtained from his sample, and multiplex PCR and PCR-reverse blot hybridization assay indicated that the isolate was a member of the M. tuberculosis complex, but was not M. tuberculosis. Finally, sequence analysis of 16S ribosomal RNA and DNA gyrase, subunit B (gyrB) suggested that the organism was M. bovis or M. bovis BCG. Although we could not confirm that M. bovis BCG was the causative agent, the results of the 3 molecular methods and the MPT-64 antigen assay suggest this finding. This is an important finding, especially because M. bovis BCG cannot be identified using common commercial molecular genetics tools.
Administration, Intravesical
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Aged
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BCG Vaccine/administration & dosage/*adverse effects
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DNA Gyrase/genetics
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Humans
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Male
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Mycobacterium Infections/*diagnosis/etiology
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Mycobacterium bovis/genetics/*isolation & purification
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Polymerase Chain Reaction
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RNA, Ribosomal, 16S/genetics
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Urinary Bladder Neoplasms/*therapy