1.Safety and Efficacy of Everolimus-Eluting Bioresorbable Vascular Scaffold Versus Second-Generation Drug-Eluting Stents in Real-World Practice
Joo Myung LEE ; Hyun Sung JOH ; Ki Hong CHOI ; David HONG ; Taek Kyu PARK ; Jeong Hoon YANG ; Young Bin SONG ; Jin-Ho CHOI ; Seung-Hyuk CHOI ; Jin-Ok JEONG ; Jong-Young LEE ; Young Jin CHOI ; Jei-Keon CHAE ; Seung-Ho HUR ; Jang-Whan BAE ; Ju-Hyeon OH ; Kook-Jin CHUN ; Hyun-Joong KIM ; Byung Ryul CHO ; Doosup SHIN ; Seung Hun LEE ; Doyeon HWANG ; Hyun-Jong LEE ; Ho-Jun JANG ; Hyun Kuk KIM ; Sang Jin HA ; Eun-Seok SHIN ; Joon-Hyung DOH ; Joo-Yong HAHN ; Hyeon-Cheol GWON ; On behalf of the SMART-REWARD Investigators
Journal of Korean Medical Science 2023;38(5):e34-
Background:
The risk of device thrombosis and device-oriented clinical outcomes with bioresorbable vascular scaffold (BVS) was reported to be significantly higher than with contemporary drug-eluting stents (DESs). However, optimal device implantation may improve clinical outcomes in patients receiving BVS. The current study evaluated mid-term safety and efficacy of Absorb BVS with meticulous device optimization under intravascular imaging guidance.
Methods:
The SMART-REWARD and PERSPECTIVE-PCI registries in Korea prospectively enrolled 390 patients with BVS and 675 patients with DES, respectively. The primary endpoint was target vessel failure (TVF) at 2 years and the secondary major endpoint was patientoriented composite outcome (POCO) at 2 years.
Results:
Patient-level pooled analysis evaluated 1,003 patients (377 patients with BVS and 626 patients with DES). Mean scaffold diameter per lesion was 3.24 ± 0.30 mm in BVS group.Most BVSs were implanted with pre-dilatation (90.9%), intravascular imaging guidance (74.9%), and post-dilatation (73.1%) at proximal to mid segment (81.9%) in target vessel.Patients treated with BVS showed comparable risks of 2-year TVF (2.9% vs. 3.7%, adjusted hazard ratio [HR], 1.283, 95% confidence interval [CI], 0.487–3.378, P = 0.615) and 2-year POCO (4.5% vs. 5.9%, adjusted HR, 1.413, 95% CI, 0.663–3.012,P = 0.370) than those with DES. The rate of 2-year definite or probable device thrombosis (0.3% vs. 0.5%, P = 0.424) was also similar. The sensitivity analyses consistently showed comparable risk of TVF and POCO between the 2 groups.
Conclusion
With meticulous device optimization under imaging guidance and avoidance of implantation in small vessels, BVS showed comparable risks of 2-year TVF and device thrombosis with DES.
2.Comparison of Factors Associated With Direct Versus Transferred-in Admission to Government-Designated Regional Centers Between Acute Ischemic Stroke and Myocardial Infarction in Korea
Dae-Hyun KIM ; Seok-Joo MOON ; Juneyoung LEE ; Jae-Kwan CHA ; Moo Hyun KIM ; Jong-Sung PARK ; Byeolnim BAN ; Jihoon KANG ; Beom Joon KIM ; Won-Seok KIM ; Chang-Hwan YOON ; Heeyoung LEE ; Seongheon KIM ; Eun Kyoung KANG ; Ae-Young HER ; Cindy W YOON ; Joung-Ho RHA ; Seong-Ill WOO ; Won Kyung LEE ; Han-Young JUNG ; Jang Hoon LEE ; Hun Sik PARK ; Yang-Ha HWANG ; Keonyeop KIM ; Rock Bum KIM ; Nack-Cheon CHOI ; Jinyong HWANG ; Hyun-Woong PARK ; Ki Soo PARK ; SangHak YI ; Jae Young CHO ; Nam-Ho KIM ; Kang-Ho CHOI ; Juhan KIM ; Jae-Young HAN ; Jay Chol CHOI ; Song-Yi KIM ; Joon-Hyouk CHOI ; Jei KIM ; Min Kyun SOHN ; Si Wan CHOI ; Dong-Ick SHIN ; Sang Yeub LEE ; Jang-Whan BAE ; Kun Sei LEE ; Hee-Joon BAE
Journal of Korean Medical Science 2022;37(42):e305-
Background:
There has been no comparison of the determinants of admission route between acute ischemic stroke (AIS) and acute myocardial infarction (AMI). We examined whether factors associated with direct versus transferred-in admission to regional cardiocerebrovascular centers (RCVCs) differed between AIS and AMI.
Methods:
Using a nationwide RCVC registry, we identified consecutive patients presenting with AMI and AIS between July 2016 and December 2018. We explored factors associated with direct admission to RCVCs in patients with AIS and AMI and examined whether those associations differed between AIS and AMI, including interaction terms between each factor and disease type in multivariable models. To explore the influence of emergency medical service (EMS) paramedics on hospital selection, stratified analyses according to use of EMS were also performed.
Results:
Among the 17,897 and 8,927 AIS and AMI patients, 66.6% and 48.2% were directly admitted to RCVCs, respectively. Multivariable analysis showed that previous coronary heart disease, prehospital awareness, higher education level, and EMS use increased the odds of direct admission to RCVCs, but the odds ratio (OR) was different between AIS and AMI (for the first 3 factors, AMI > AIS; for EMS use, AMI < AIS). EMS use was the single most important factor for both AIS and AMI (OR, 4.72 vs. 3.90). Hypertension and hyperlipidemia increased, while living alone decreased the odds of direct admission only in AMI;additionally, age (65–74 years), previous stroke, and presentation during non-working hours increased the odds only in AIS. EMS use weakened the associations between direct admission and most factors in both AIS and AMI.
Conclusions
Various patient factors were differentially associated with direct admission to RCVCs between AIS and AMI. Public education for symptom awareness and use of EMS is essential in optimizing the transportation and hospitalization of patients with AMI and AIS.
3.Is it possible to reduce intra-hospital transport time for computed tomography evaluation in critically ill cases using the Easy Tube Arrange Device?.
Kyung Hyeok SONG ; Sung Uk CHO ; Jin Woong LEE ; Yong Chul CHO ; Won Joon JEONG ; Yeon Ho YOU ; Seung RYU ; Seung Whan KIM ; In Sool YOO ; Ki Hyuk JOO
Clinical and Experimental Emergency Medicine 2018;5(1):14-21
OBJECTIVE: Patients are often transported within the hospital, especially in cases of critical illness for which computed tomography (CT) is performed. Since increased transport time increases the risks of complications, reducing transport time is important for patient safety. This study aimed to evaluate the ability of our newly invented device, the Easy Tube Arrange Device (ETAD), to reduce transport time for CT evaluation in cases of critical illness. METHODS: This prospective randomized control study included 60 volunteers. Each participant arranged five or six intravenous fluid lines, monitoring lines (noninvasive blood pressure, electrocardiography, central venous pressure, arterial catheter), and therapeutic equipment (O2 supply device, Foley catheter) on a Resusci Anne mannequin. We measured transport time for the CT evaluation by using conventional and ETAD method. RESULTS: The median transport time for CT evaluation was 488.50 seconds (95% confidence interval [CI], 462.75 to 514.75) and, 503.50 seconds (95% CI, 489.50 to 526.75) with 5 and 6 fluid lines using the conventional method and 364.50 seconds (95% CI, 335.00 to 388.75), and 363.50 seconds (95% CI, 331.75 to 377.75) with ETAD (all P < 0.001). The time differences were 131.50 (95% CI, 89.25 to 174.50) and 148.00 (95% CI, 116.00 to 177.75) (all P < 0.001). CONCLUSION: The transport time for CT evaluation was reduced using the ETAD, which would be expected to reduce the complications that may occur during transport in cases of critical illness.
Blood Pressure
;
Central Venous Pressure
;
Critical Illness*
;
Electrocardiography
;
Humans
;
Manikins
;
Methods
;
Patient Safety
;
Prospective Studies
;
Transportation
;
Volunteers
4.Trigger Wrist.
Il Jung PARK ; Yoon Min LEE ; Seung Koo RHEE ; Seok Whan SONG ; Hyung Min KIM ; Ki Bum CHOI
Clinics in Orthopedic Surgery 2015;7(4):523-526
Trigger wrist is a relatively rare disease compared to trigger finger, which is the most common disorder found in hands. Patients with trigger wrist usually complain about the following symptoms: snapping and clicking or triggering around carpal tunnel with or without mild to moderate median neuropathy. There are a total of five cases of trigger wrist: three cases of anomalous muscle belly of flexor digitorum superficialis and two cases of fibroma around flexor tendon sheath within carpal tunnel. This study reports on two of those cases: one with anomalous muscle and the other with fibroma of flexor tendon sheath. Accurate examination and proper diagnosis are mandatory to obviate improper and time-wasting treatment for patients with trigger wrist.
Adult
;
Female
;
Fibroma
;
Humans
;
Male
;
*Tenosynovitis/physiopathology/radiography/surgery
;
*Wrist/physiopathology/radiography/surgery
5.Dorsal Plate Fixation for Dorsally Displaced Distal Radius Fractures.
Ki Tae NA ; Seok Whan SONG ; Yoon Min LEE ; Byung Min KANG
Journal of the Korean Society for Surgery of the Hand 2014;19(1):44-51
PURPOSE: The object of this study is to evaluate the clinical and radiographic outcomes of two different kinds of dorsal plating for dorsally displaced distal radius fractures. METHODS: Forty-three patients with dorsal plate fixation for distal radius fracture were retrospectively reviewed. Twenty-four patients were treated with nonlocking dorsal plate (group I) and nineteen patients with locking dorsal plate (group II). Range of motion and Green and O'Brien score were evaluated as clinical results, and radial inclination, radial length, volar tilt at postoperative and last follow up were evaluated as radiographic results. RESULTS: According to AO classification system, there were 18 type A fractures, 4 type B fractures, 21 type C fractures. In group I, the mean flexion and extension were 65.0degrees and 65.3degrees, respectively; ulnar and radial deviation were 25.5degrees and 20.8degrees; pronation and supination were 80.0degrees and 80.4degrees. In group II, the mean flexion and extension were 64.5degrees and 67.3degrees, respectively; ulnar and radial deviation were 30.6degrees and 20.6degrees; pronation and supination were 81.4degrees and 78.6degrees. The mean Green and O'Brien score was 94.4 in group I and 92.2 in group II, and 41 patients had satisfactory result. There was no statistical significant difference in clinical results between the groups. Results of postoperative and last follow-up radiographic analyses for mean radial inclination were 23.9degrees and 24.1degrees in group I, respectively, and 24.2degrees and 24.9degrees in group II; radial length were 9.9 mm and 9.7 mm in group I, and 10.1 mm and 9.2 mm in group II; mean volar tilt were 12.2degrees and 13.1degrees in group I, and 14.8degrees and 13.7degrees in group II. There were no statistical significant changes within radiographic parameters. No extensor tendon rupture was reported. CONCLUSION: Dorsal plate fixation for dorsally displaced distal radius fracture showed satisfactory clinical and radiographic outcomes with low complication rate, regardless of the type of plate.
Classification
;
Follow-Up Studies
;
Humans
;
Pronation
;
Radius Fractures*
;
Radius*
;
Range of Motion, Articular
;
Retrospective Studies
;
Rupture
;
Supination
;
Tendons
6.Treatment of Humeral Shaft Fracture with Retrograde Intramedullary Nail.
Ki Bum CHOI ; Soo Hwan KANG ; Yoon Min LEE ; Seok Whan SONG ; Youn Jun KIM
Journal of the Korean Fracture Society 2013;26(4):299-304
PURPOSE: The purpose of this study was to report the outcome of treatment of humeral shaft fracture with retrograde intramedullary nail of advanced insertion opening. MATERIALS AND METHODS: From April 2005 and August 2012, 22 patients with a humeral shaft fracture were treated by a single surgeon using the technique of retrograde intramedullary nail at Department of Orthopedic Surgery, Yeouido St. Mary's Hospital (Seoul, Korea). To avoid causing fractures at the insertion site, the entry point was more distally located than conventionally, and was extended proximally to include the proximal marginal cortex of the olecranon fossa. The outcome was evaluated clinically and radiologically. RESULTS: The mean period of achievement of bony was 5.8 months (4-11 months). Additional fixations were needed in one patient with intraoperative lateral condylar fracture and 2 patients with postoperative nonunion. There were no limitations of movement or pain in the shoulder joint, and 8 cases had a 6.5degrees flexion contracture on average. CONCLUSION: This retrograde intramedullary fixation technique using a distal entry portal near the olecranon fossa is particularly useful in humeral shaft fractures without a neurovascular injury. The risk of an intraoperative fracture (supracondylar fracture or fracture around the entry portal) can be decreased using this treatment. We recommend this technique because of the safety and the satisfactory outcome.
Contracture
;
Humans
;
Olecranon Process
;
Orthopedics
;
Shoulder Joint
7.Posterior-Posterior Dual Plates Fixation for the Distal Humerus Fractures.
Yoon Min LEE ; Seok Whan SONG ; Ki Bum CHOI ; Yoo Joon SUR ; Sung Eun KIM
Journal of the Korean Fracture Society 2013;26(4):254-260
PURPOSE: Fractures of the distal humerus are one of the challenging injuries due to its complex anatomy and accompanied comminution. For dual plate fixation, orthogonal or parallel plating is widely used, but the better of the two is debatable. The purpose of this study was to report another fixation technique that yielded good clinical results with early bone union of distal humerus fracture, namely, posterior-posterior plate fixation. MATERIALS AND METHODS: From March 2003 to March 2012, 20 patients with distal humerus fractures were treated by posterior-posterior plate fixation. The triceps reflecting approach was used with anterior transposition of the ulnar nerve. The mean age at the time of injury was 45 years (range, 26 to 78 years). By AO classification of distal humerus fractures, there were one case of A2 and B3 respectively, two cases of each A3, C1 and C3, and twelve cases of C2. RESULTS: The mean period of complete bone union was 7.1 weeks (range, 4 to 11 weeks). The mean flexion-extension range of motion of the elbow joint at last follow-up was 116.2 degrees. The mean pronation was 81.2 degrees and supination was 83.1 degrees. Plates and screws were removed at about nine months after the initial surgery. No cases showed complications or required additional operation. CONCLUSION: Posterior-posterior dual plates fixation resulted in stable bicortical screw fixation, and insertion of lag screws were possible without interference. Posterior-posterior plating could be an easy and stable fixation method that provides good clinical results.
Elbow Joint
;
Follow-Up Studies
;
Humans
;
Humerus*
;
Pronation
;
Range of Motion, Articular
;
Supination
;
Ulnar Nerve
8.Metastasis of Renal Cell Carcinoma to the Bladder.
Seung Whan DOO ; Woong Bin KIM ; Bong Ki KIM ; Won Jae YANG ; Jong Hyun YOON ; So Young JIN ; Yun Seob SONG
Korean Journal of Urology 2013;54(1):69-72
Renal cell carcinoma is an uncommon source of bladder metastases. Here we report a case of renal cell carcinoma that metastasized to the bladder. A 73-year-old woman complained of gross hematuria. Abdominopelvic computerized tomography showed a bladder mass and a heterogenous enhancing mass in the lower pole of the left kidney with left vein thrombosis. The pathological analysis of the resected bladder specimen revealed metastatic renal cell carcinoma of the clear cell type.
Carcinoma, Renal Cell
;
Female
;
Hematuria
;
Humans
;
Kidney
;
Neoplasm Metastasis
;
Thrombosis
;
Urinary Bladder
;
Veins
9.Trends in the Incidence of Hospitalized Acute Myocardial Infarction and Stroke in Korea, 2006-2010.
Rock Bum KIM ; Byoung Gwon KIM ; Yu Mi KIM ; Jeong Wook SEO ; Young Shil LIM ; Hee Sook KIM ; Hey Jean LEE ; Ji Young MOON ; Keon Yeop KIM ; Ji Yeon SHIN ; Hyeung Keun PARK ; Jung Kook SONG ; Ki Soo PARK ; Baek Geun JEONG ; Chan Gyeong PARK ; Hee Young SHIN ; Jong Won KANG ; Gyung Jae OH ; Young Hoon LEE ; In Whan SEONG ; Weon Seob YOO ; Young Seoub HONG
Journal of Korean Medical Science 2013;28(1):16-24
This study attempted to calculate and investigate the incidence of hospitalized acute myocardial infarction (AMI) and stroke in Korea. Using the National Health Insurance claim data, we investigated patients whose main diagnostic codes included AMI or stroke during 2006 to 2010. As a result, we found out that the number of AMI hospitalized patients had decreased since 2006 and amounted to 15,893 in 2010; and that the number of those with stroke had decreased since 2006 and amounted to 73,501 in 2010. The age-standardized incidence rate of hospitalized AMI, after adjustment for readmission, was 41.6 cases per 100,000-population in 2006, and had decreased to 29.4 cases in 2010 (for trend P < 0.001). In the case of stroke was estimated at 172.8 cases per 100,000-population in 2006, and had decreased to 135.1 cases in 2010 (for trend P < 0.001). In conclusion, the age-standardized incidence rates of both hospitalized AMI and stroke in Korea had decreased continuously during 2006 to 2010. We consider this decreasing trend due to the active use of pharmaceuticals, early vascular intervention, and the national cardio-cerebrovascular disease care project as the primary and secondary prevention efforts.
Acute Disease
;
Adolescent
;
Adult
;
Age Factors
;
Aged
;
Aged, 80 and over
;
Child
;
Child, Preschool
;
Female
;
Hospitalization/*trends
;
Humans
;
Incidence
;
Infant
;
Infant, Newborn
;
Male
;
Middle Aged
;
Myocardial Infarction/*epidemiology
;
Patient Readmission
;
Republic of Korea/epidemiology
;
Sex Factors
;
Stroke/*epidemiology
;
Young Adult
10.Multicenter Study on the Clinician's Diagnostic and Therapeutic Approaches for Benign Paroxysmal Positional Vertigo in Korea
Eun Ju JEON ; Won Ho CHUNG ; Jeong Hwan CHOI ; Eui Cheol NAM ; Hong Ju PARK ; Jong Dae LEE ; Won Sang LEE ; Kyu Sung KIM ; Eui Kyung GOH ; Ja Won KOO ; Min Bum KIM ; Min Beom KIM ; Se Hyung KIM ; Young Jin KIM ; Chang Hee KIM ; Sung Il NAM ; Seog Kyun MUN ; Ga Young PARK ; Sang Yoo PARK ; Shi Nae PARK ; Chang Hoon BAE ; Sung Hyun BOO ; Myung Whan SUH ; Jae Hyun SEO ; Eun Jin SON ; Jae Jun SONG ; Jae Jin SONG ; Joong Wook SHIN ; Dae Bo SHIM ; Seong Ki AHN ; Hye Youn YOUM ; Shin Young YOO ; Dong Hee LEE ; Seung Hwan LEE ; Chang Ho LEE ; Hyun Seok LEE ; Hwan Ho LEE ; Hyo Jeong LEE ; Yun Hoon CHOUNG ; Seung Hyo CHOI ; Jee Sun CHOI ; Seok Min HONG ; Sung Kwang HONG
Journal of the Korean Balance Society 2013;12(3):79-92
BACKGROUND AND OBJECTIVES: It is necessary to establish the most efficient diagnostic and therapeutic method for benign paroxysmal positional vertigo (BPPV), which is appropriate for Korean healthcare system. We aimed to evaluate current state of Korean clinician's diagnostic and therapeutic approaches for BPPV. MATERIALS AND METHODS: A 16-item survey was emailed to the members of dizziness department of Otology Research Interest Group in the Korean Otologic Society (n=68). 43 were returned and analyzed. RESULTS: All respondents (100%) used Dix-Hallpike test as a diagnostic tool for vertical canal-BPPV. Supine roll test was used for diagnosing lateral canal BPPV in nearly all the respondents (97.7%). Epley maneuver was chosen as otolith repositioning maneuver (ORM) for posterior canal BPPV in all respondents and barbecue rotation (BBQ) was used for treating lateral canal BPPV with geotropic nystagmus in 95.3% of respondents. Extreme variation was noted for therapeutic approach of lateral canal BPPV with ageotropic nystagmus BBQ, with 4 kinds of ORM and adjunctive measures to liberate otolith from cupula, while BBQ was again the most commonly used ORM (76.7%). CONCLUSION: The development of practical and efficient ORM for lateral canal BPPV with ageotropic nystagmus is necessary.
Surveys and Questionnaires
;
Delivery of Health Care
;
Dizziness
;
Electronic Mail
;
Korea
;
Otolaryngology
;
Otolithic Membrane
;
Public Opinion
;
Vertigo

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