1.Sexual behavior in cervical cancer patients.
Haeng Su KIM ; Tchan Kyu PARK ; Dong Up HAN ; Ki Hong CHANG ; Hyung Sun KIM
Korean Journal of Obstetrics and Gynecology 1993;36(8):3317-3325
No abstract available.
Humans
;
Sexual Behavior*
;
Uterine Cervical Neoplasms*
3.A case of isolated ACTH deficiency.
Seung Won CHOI ; Ki Up LEE ; Dong Wan SEO ; Ghi Su KIM ; Munho LEE
Journal of Korean Society of Endocrinology 1992;7(4):397-401
No abstract available.
Adrenocorticotropic Hormone*
4.Improvement of Metabolic Syndrom by Alpha-lipoic Acid.
Eun Hee KOH ; Woo Je LEE ; Min Seon KIM ; Joong Yeol PARK ; Ki Up LEE
Journal of Korean Society of Endocrinology 2004;19(3):267-273
No abstract available.
Thioctic Acid*
5.Autonomously functioning thyroid nodules.
Young Kee SHONG ; Ki Up LEE ; Ghi Su KIM ; Munho LEE
Journal of Korean Society of Endocrinology 1992;7(2):121-126
No abstract available.
Thyroid Gland*
;
Thyroid Nodule*
6.Clinical Features of Multiple Endocrine Neoplasia Type I in Koreans
Chul Hee KIM ; Ghi Su KIM ; Hong Kyu KIM ; Joong Yeol PARK ; Young Kee SHONG ; Ki Up LEE
Journal of Korean Society of Endocrinology 1996;11(2):163-174
Background: Multiple endocrine neoplasia type I(MEN I) is a rare, eomplex, and potentially lethal disease. In Korean, only five anecdotal cases were reported as yet. The authors rescently experienced four cases of MEN I, and analysed the clinieal characteristics of MEN I in Koreans. Methods: The authors evaluated nine cases of MEN I, retrospectively. Four cases were analysed by clinical records in patients admitted to Asan Medical Center and five cases were reviewed by previously reported Korean literature from 1986 to 1995. Results: The average age was 39 years(ranged from 33 to 59 years). Eight of the nine patients had hyperparathyroidism documented by elevated serum calcium and PTH level with or without evidence of parathyroid mass. Initial presenting manifestations were symptomatic urinary stone, hypoglycernia due to insulinoma, hypogonadism, acromegaly, or peptic ulcer. Eight of nine patients had pancreatic islet cell tumors, and three of them were be malignant by radiologic and/or pathologic findings. The pancreatic tumors produced various hormones, such as gastrin, insulin, glucagon, or combination of them. Six of the nine cases had pituitary lesion. The most cornmon pituitary tumor was prolactinoma and the remaining was GH or GH and TSH producing tumor. In addition to the major components of MEN I, four had adrenocortical hyperplasia or adenoma and two had carcinoid tumor. There was only one familial case. Conclusion: The clinical charateristics of MEN I in Korean are mostly not different from the previous reports except older age at diagnosis, more comrnon adrenal involvement(44%) and gastrointestinal carcinoid tumor(22%). Although only one case was familial, more cases could be found if careful screening were done for the family members of the MBN I patients. In addition, screening and close follow up for endocrine pancreatic tumors are required for MEN I patients without detectable pancreatic lesion becau~se the malignant potential of pancreatic tumors has beeome an increasing concem for the prognosis of MEN I.
Acromegaly
;
Adenoma
;
Asian Continental Ancestry Group
;
Calcium
;
Carcinoid Tumor
;
Chungcheongnam-do
;
Diagnosis
;
Follow-Up Studies
;
Gastrins
;
Glucagon
;
Humans
;
Hyperparathyroidism
;
Hyperplasia
;
Hypogonadism
;
Insulin
;
Insulinoma
;
Islets of Langerhans
;
Mass Screening
;
Multiple Endocrine Neoplasia Type 1
;
Multiple Endocrine Neoplasia
;
Peptic Ulcer
;
Pituitary Neoplasms
;
Prognosis
;
Prolactinoma
;
Retrospective Studies
;
Urinary Calculi
7.A case of osteoporosis associated with pernicious anemia.
Sang Wook KIM ; Seung Won CHOI ; Jung Shin LEE ; Joong Yeol PARK ; Ki Up LEE ; Ghi Su KIM
Journal of Korean Society of Endocrinology 1993;8(3):351-355
No abstract available.
Anemia, Pernicious*
;
Osteoporosis*
8.Cellular analysis and measurement of mucin in sputum of chronic airway disease.
Ki Up KIM ; Yang Ki KIM ; Chan Young SHIN ; Do Jin KIM ; Soo Taek UH ; Yong Hoon KIM ; Kwang Ho KO ; Choon Sik PARK
Tuberculosis and Respiratory Diseases 2000;49(1):82-92
BACKGROUND: In chronic airway disease, mucus secretion in increased, but extraction of mucin, which is the main component of mucus secretion, is a very complicated and limited in clinical use. Recently, monoclonal antibody for mucin was developed for possible clinical use. In this study, cellular analysis and quantification of respiratory mucin in sputum of patients with chronic airway diseases were performed. METHOD: Sputum was collected from patients with asthma(n=33), bronchiectasis(n=8) or chronic bronchitis(n=13) by spontaneous expectoration or by hypertonic saline induction, Collected sputums was treated by 0.1% dithiotreitol to dissociate the disulfide bond of the mucus and filtered through a nylon gauze. Total cell count, viability and differential count were measured. For detection of mucin, collected samples were treated with sodium dodoecyl sulfate polyacrylamide gel electrophoresis and then with monoclonal antibody(HMO2), as the primary antibody, and PAS stain. The amount of mucin was measured with ELISA by HMO2. Correlation with clinical information, cellular analysis, and amount of measured mucin were analyzed. RESULTS: Total cell counts of sputum were significantly increased in patients with bronchiectasis but viability remained the same. Eosinophils were significantly increased in patients with asthma, neutrophils in bronchiectasis chronic bronchitis, respectively (p<0.05). The results of Western blotting and PAS staining confirmed the presence of glycoproteins and matched? with mucin. The amounts of mucin measured by ELISA were not significantly different among the disease groups. Significant correlation was identified between the amount of mucin and viability(r=-0.482, p<0.05). CONCLUSION: Inflammatory cells in the sputum of those with chronic airway disease were different for each disease type. Measurement of mucin by ELISA via monoclonal antibodies may be a simple method for the evaluation of chronic airway disease.
Antibodies, Monoclonal
;
Asthma
;
Blotting, Western
;
Bronchiectasis
;
Bronchitis, Chronic
;
Cell Count
;
Electrophoresis, Polyacrylamide Gel
;
Enzyme-Linked Immunosorbent Assay
;
Eosinophils
;
Glycoproteins
;
Humans
;
Mucins*
;
Mucus
;
Neutrophils
;
Nylons
;
Sodium
;
Sputum*
9.Comparison of Barium Reduction and Pneumatic Reduction of Intussusception in Children: A Surgeon's View.
Ki Seog LEE ; Young Up CHO ; Kyung Rae KIM
Journal of the Korean Surgical Society 2000;59(4):526-531
PURPOSE: Pneumatic reduction has rapidly replaced traditional barium reduction owing to its potential advantages, such as higher reduction rate and greater safety; however, the effects on surgery after reduction failure have not been studied. In this study, we evaluated the influences of attempted barium and pneumatic reductions on subsequent surgical procedures. METHODS: One hundred and sixty-one barium reductions were performed on 158 patients while 153 pneumatic reductions were performed on 145 patients. Statistical comparisons of these two reduction methods were made regarding the following variables: the reduction rates, frequencies of bowel perforations and recurrences, mean operation times, fasting periods, and durations of admission. RESULTS: The reduction rates were similar for both groups with barium reduction being successful in 67.1% of the cases (108/161) and pneumatic reduction in 69.3% (106/153). Two cases of bowel perforation occurred during the pneumatic reductions, none were noted during the barium reductions. Recurrence of intussusception was noted in three cases initially reduced with barium and in nine cases reduced pneumatically. The mean operation time (130.7 minutes vs. 81.7 minutes), postoperative fasting time (61.6 hours vs. 37.6 hours), and duration of admission (6.7 days vs. 5.4 days) were significantly prolonged in the pneumatic reduction group. CONCLUSION: A part from a comparable reduction rate pneumatic reduction demonstrated no favorable outcome relative to barium reduction. Furthermore, it resulted in some obstacles to surgery and recovery, such as prolonged operation time, fasting period, and duration of admission.
Barium*
;
Child*
;
Fasting
;
Humans
;
Intussusception*
;
Recurrence
10.Tuberculous abscess of the thyroid.
Seon Mee PARK ; Young Kee SHONG ; Ki Up LEE ; Ghi Su KIM ; Munho LEE ; Kun Choon PARK
Journal of Korean Society of Endocrinology 1992;7(2):149-152
No abstract available.
Abscess*
;
Thyroid Gland*