Herpes zoster is generally believed to be caused by the activation of varicella-zoster virus present in the body since an original infection with varicella. According to the thesis, the virus remairis in a latent state in the cells of the sensory ganglia until immunity has waned sufficiently to pezmit multiplication of the virus and clinical infection. There are a number of reports that in patient with malignant disease, especially Jymphoma, a frequenry af association of zoster is greater and severity of its symptom is increased to be marked contrast to the benign uneventful course of zoster seen in healthy person. The author observed one case of zoster seen in patient with malignant disorder, and frequency of association of zoster in malignant disease and its etiological factors are reviewed in the literature.
Chickenpox ; Ganglia, Sensory ; Herpes Zoster* ; Herpesvirus 3, Human ; Humans ; Lymphoma, Non-Hodgkin*

Grave's disease is an autoimmune disorder and affects thyroid gland and orbit. Ocular manifestations of this disease, referred to as Grave's ophthalmopathy are caused by deposition of antithyroglobulin immune complexes into extraocular muscles and orbital fats. Consequent increase in volume of orbital contents results in exopthalmos. Severe exopthalmos results in several significant visual consequences as follows: exposure keratitis, diplopia and optic neuropathy. Orbital decompression for Grave's ophthalmopathy has traditionally been performed through either an external or a transantral approach. The advent of intranasal endoscopes allowed for the development of a transnasal approach for medial and inferior orbital wall decompression. Recently, the authors experienced a case of Grave's ophthalmopathy complicated with exposure keratitis and performed endoscopic transnasal orbital decompression, so report this case with a review of literature.
Antigen-Antibody Complex ; Decompression* ; Diplopia ; Endoscopes ; Fats ; Keratitis ; Muscles ; Optic Nerve Diseases ; Orbit* ; Thyroid Gland

No abstract available.
Fertilization in Vitro* ; Humans* ; Micromanipulation* ; Pregnancy Rate* ; Pregnancy*

No abstract available.
Hemorrhoidectomy* ; Hemorrhoids* ; Ligation* ; Rubber*

PURPOSE: The present study investigated the impact of 2 different suture techniques, the conventional crossed mattress suture (X suture) and the novel hidden X suture, for alveolar ridge preservation (ARP) with an open healing approach. METHODS: This study was a prospective randomized controlled clinical trial. Fourteen patients requiring extraction of the maxillary or mandibular posterior teeth were enrolled and allocated into 2 groups. After extraction, demineralized bovine bone matrix mixed with 10% collagen (DBBM-C) was grafted and the socket was covered by porcine collagen membrane in a double-layer fashion. No attempt to obtain primary closure was made. The hidden X suture and conventional X suture techniques were performed in the test and control groups, respectively. Cone-beam computed tomographic (CBCT) images were taken immediately after the graft procedure and before implant surgery 4 months later. Additionally, the change in the mucogingival junction (MGJ) position was measured and was compared after extraction, after suturing, and 4 months after the operation. RESULTS: All sites healed without any complications. Clinical evaluations showed that the MGJ line shifted to the lingual side immediately after the application of the X suture by 1.56±0.90 mm in the control group, while the application of the hidden X suture rather pushed the MGJ line slightly to the buccal side by 0.25±0.66 mm. It was demonstrated that the amount of keratinized tissue (KT) preserved on the buccal side was significantly greater in the hidden X suture group 4 months after the procedure (P<0.05). Radiographic analysis showed that the hidden X suture had a significant effect in preserving horizontal width and minimizing vertical reduction in comparison to X suture (P<0.05). CONCLUSIONS: Our study provided clinical and radiographic verification of the efficacy of the hidden X suture in preserving the width of KT and the dimensions of the alveolar ridge after ARP.
Alveolar Process* ; Bone Matrix ; Bone Regeneration ; Bone Resorption ; Collagen ; Humans ; Membranes ; Prospective Studies ; Suture Techniques* ; Sutures* ; Tooth ; Tooth Extraction ; Transplants

The wrist joint is composed of midcarpal, radiocarpal and distal radioulnar joints. It is difficult to analyze the motion of these joints by the simple roentgenogram. We reconstructed three dimensional images of the wrist and distal radius from computerized tomogram using a new interactive graphics software written in Pascal and Turbo Graphic. There were 10 normal wrists in neutral position, and two normal and one abnormal wrists in ulnar-radial deviation and one normal wrist in flexion-extension were analyzed in this study. For simplification, the images were reformatted for the scaphoid, the proximal carpal row, the distal carpal row and the distal radius. We established the three dimensional references for wrist by defining the Z axis as the long axis of radius, the X axis as a line which is in horizontal plane and parallel to the anterior cortex of distal radius about 2 cm proximal to the articular surface and the Y axis as the automatically defined line perpendicular to both X and Z axes. We measured the angles between the X-axis and the reference lines of scaphoid and each carpal rows. The scaphoid was internally rotated by 60,0 degrees from X axis, the proximal carpal row by 7.0 degrees and the distal carpal row by 25.6 degrees each. There was only minimal change in the angles during the ulnar and radial deviation. The pattern of angles in abnormal wrist was different from those in normal wrists. In flexion-extension, the angle of distal carpal row was changed significantly, which means there was some error in selecting the reference line of distal carpal row as an axis of motion, or in measuring the angles, or it can be suggested that there is some rotational motion of distal carpal row on the Z axis. The proximal poles of the scaphoid and the triquetrum were displaced ventrally during flexion and dorsally during extension.
Imaging, Three-Dimensional ; Joints ; Radius ; Wrist Joint ; Wrist

PURPOSE: The objective of this study was to evaluate the effect of microthreads on removal torque and bone-to-implant contact (BIC). METHODS: Twelve miniature pigs for each experiment, a total of 24 animals, were used. In the removal torque analysis, each animal received 2 types of implants in each tibia, which were treated with sandblasting and acid etching but with or without microthreads at the marginal portion. The animals were sacrificed after 4, 8, or 12 weeks of healing. Each subgroup consisted of 4 animals, and the tibias were extracted and removal torque was measured. In the BIC analysis, each animal received 3 types of implants. Two types of implants were used for the removal torque test and another type of implant served as the control. The BIC experiment was conducted in the mandible of the animals. The P1-M1 teeth were extracted, and after a 4-month healing period, 3 each of the 2 types of implants were placed, with one type on each side of the mandible, for a total of 6 implants per animal. The animals were sacrificed after a 2-, 4-, or 8-week healing period. Each subgroup consisted of 4 animals. The mandibles were extracted, specimens were processed, and BIC was analyzed. RESULTS: No significant difference in removal torque value or BIC was found between implants with and without microthreads. The removal torque value increased between 4 and 8 weeks of healing for both types of implants, but there was no significant difference between 8 and 12 weeks. The percentage of BIC increased between 2 and 4 weeks for all types of implants, but there was no significant difference between 4 and 8 weeks. CONCLUSIONS: The existence of microthreads was not a significant factor in mechanical and histological stability.
Animals ; Biomechanics ; Dental Implants ; Mandible ; Osseointegration ; Swine ; Tibia ; Tooth ; Torque

PURPOSE: To describe the CT findings of automastoidectomy caused by cholesteatoma, and to evaluate the natural course of cholesteatoma by comparing it with the postmastoidectomy defect of the temporal bone. MATERIALS AND METHODS: We retrospectively reviewed the CT findings of 15 cases of automastoidectomy in 13 patients with cholesteatoma and of 14 cases of postmastoidectomy in 13 patients. RESULTS: In automastoidectomy, the posterior walls of bony defects of the temporal bone were thinner (mean thickness in automastoidec/postmastoidec tomy :2mm/3.5 mm) and smoother(n=10) than those of bony defects in postmastoidectomy(n=6). Defects of the posterosuperior wall of the bony external auditory canal were present in all cases of automastoidectomy(100%) andmost of postmastoidectomy(79%). there were gross defects of the lateral bony cortex of the mastoid(71%), Henle'sspine(100%), and the postero superior extension of the exit of bony defect(100%) in cases of postmastoidectomy(n=10), but there were rare findings in cases of automastoidectomy(20%, 21%, 23%, respectively).There were soft tissue densities within the bony defect and sinus tympani in all cases of automastoidectomy(100%)and in some cases of postmastoidectomy(64% and 36% respectively). CONCLUSION: When comparing automastoidectomyand postmastoidectomy, CT findings concerning bony defects were different with regard to the remaining posteriorwall, the extent of bony defect, and the presence of findings which suggested an active disease process. These differences are helpful in differentiating automastoidectomy and postmastoidectomy and in understanding thenatural course of cholesteatoma.
Cholesteatoma ; Ear Canal ; Humans ; Retrospective Studies ; Temporal Bone*

BACKGROUND: In the acute phase of myocardial infarction, the hemostatic mechanism is known to be activated. However, it remains unclear whether increased activity of the hemostatic mechanism is only a marker of the acute thrombotic episode or precedes its appearance. It is also inapparent whether a hypercoagulable state persist for a prolonged period after the apparent resolution of these disorders. METHODS: In a group of 23 patients with acute myocardial infarction who received fibrinolytic therapy with urokinase(group A) or tPA(group B), the plasma level of fibrinogen, antithrombin compared to those of the 10 normal controls. RESULTS: The plasme level of fibrinogen was significantly decreased in both group A and B before and 4 to 24 hours after thrombolytic therapy compared to that of normal controls. But it was increased 7 to 14 days after thrombolytic therapy. In a few of the patients, the plasma level of FDP and D-dimer were positive before thrombolytic therapy and in the most patients they were positive 4 hours after thrombolytic therapy. The plasma level of AT-III was significantly increased in both group A and B before thrombolytic therapy compared with that of normal controls, but, after thrombolytic therapy, there was no significant change in its level. CONCLUSIONS: In the patients with acute myocardial infarction, the thrombolysis occurred before thrombolytic therapy and it lasted for 24 hours after thrombolytic therapy.
Antithrombin III* ; Fibrinogen ; Humans ; Myocardial Infarction* ; Plasma ; Thrombolytic Therapy*

To examine the relationship between gastric ulcer and gastric cancer, we investigated petients with gastric ulcer diagnosed from 1986 to l993. We reviewed the endoscopic reports and films of patients with gastric ulcer retrospectively. We excluded the patients who was diagnosed as gastric cancer in two years follow-up. The results were as follaws; 1) During follow-up of the original cohort, there were 5 patients(0.5~%) in whom gastric cancer developed at the same site initially diagnosed as gastric ulcer. The gross type of the lesion was early gastric cancer in two and advanced gastric cancer in three patients 2) The time interval between the initial diagnosis of gastric ulcer and cancer development was from 31 months to 70 months (average 51 months). 3) At the initial examination of 5 gastric cancer patients, the diagnosis was active gastric ulcer in four, multiple gastric ulcer in one, and linear gastrie ulcer in one patient. Characteristic endoscopic findjngs were gastric ulcer with clubbing mucosal folds in three and gastric ulcer with bleeding in one patient. 4) During the follow-up period, endoscopicailly and histologically healing of gastric uleer was observed in one patient and histologic finding showed chronic superficial gastritits with intestinal metaplasia. These results suggest that gastric ulcers rarely progress to gastric cancer. However if the endoscopic findings are suspicious for malignancy, then follow-up endoscopy until complete healing should be done.
Cohort Studies ; Diagnosis ; Endoscopy ; Follow-Up Studies* ; Hemorrhage ; Humans ; Metaplasia ; Stomach Neoplasms* ; Stomach Ulcer* ; Ulcer