1.Two Cases of Idiopathic pulmonary Hemosiderosis.
Sung Ky YOU ; Ki Soo KIM ; Young Jee KIM ; Young Yull KOH
Journal of the Korean Pediatric Society 1988;31(9):1209-1216
No abstract available.
Hemosiderosis*
2.Antimicrobial activity and combination effect of drugs to vibrio vulnificus.
Tai You HA ; Ki Kon OWN ; Hee Sung WHANG ; Jong Wook PARK
Journal of the Korean Society for Microbiology 1991;26(6):519-530
No abstract available.
Vibrio vulnificus*
;
Vibrio*
3.Reevaluation of the importance of finding rash, lymphadenitis and eschars for the early clinical diagnosis of Tsutsugamushi disease.
Kang Su YI ; Sung Kun YOU ; Wan KO ; Won Young LEE ; Chin Ki PAI ; Ki Il KIM ; Yunsop CHONG
Korean Journal of Infectious Diseases 1991;23(3):163-169
No abstract available.
Diagnosis*
;
Exanthema*
;
Lymphadenitis*
;
Scrub Typhus*
5.Suspicious Reperfusion Injury of Spinal Cord After Multilevel Cervical Posterior Decompression without Remarkable Surgical Insult: Two Case Reports.
Kyu Yeol LEE ; Sung Gon YOU ; Ki Woong KIM
Journal of Korean Society of Spine Surgery 2014;21(2):97-102
STUDY DESIGN: Two case reports. OBJECTIVES: We present two cases of quadriplegia after posterior decompression with fusion caused by a suspicious reperfusion injury of spinal cord without remarkable surgical insult. SUMMARY OF LITERATURE REVIEW: Posterior decompression and posterolateral fusion have been reported as effective procedures in patients with multilevel myelopathy. However, postoperative spinal cord injury without remarkable intraoperative technical damage has been reported in a few articles. Reperfusion mechanism was suggested as one of the leading causes and reported in some animal models. MATERIALS AND METHODS: There was one case of ossification of the posterior longitudinal ligament and one developmental multilevel stenosis that underwent laminectomy with lateral mass instrumentation. After surgery, the patients presented with quadriplegia; MRI demonstrated swelling of the spinal cord and intramedullary lesion in two cases. RESULTS: After surgery, the patients presented with quadriplegia; MRI demonstrated swelling of the spinal cord and intramedullary lesion in two cases. CONCLUSION: Although patients with such a medical condition are rare, it is difficult to predict postoperative swelling of the spinal cord before surgery. The surgeon should thus be aware of such rare disease conditions involving the spinal cord before the surgical procedure.
Constriction, Pathologic
;
Decompression*
;
Humans
;
Laminectomy
;
Longitudinal Ligaments
;
Magnetic Resonance Imaging
;
Models, Animal
;
Quadriplegia
;
Rare Diseases
;
Reperfusion
;
Reperfusion Injury*
;
Spinal Cord Diseases
;
Spinal Cord Injuries
;
Spinal Cord*
6.Dural Tear and Root Entrapment in Lumbar Burst Fractures.
Byung Joon SHIN ; Sang Ki KIM ; You Sung SUH ; Yon Il KIM ; Soo Kyoon RAH ; Chang Uk CHOI
Journal of Korean Society of Spine Surgery 1997;4(1):98-105
No abstract available.
7.Effect of the Physiologically Active Compounds in Phlomidis Radix on Cell Cycle Regulation in Human Gingival Fibroblasts.
Suk Joo YOU ; Kil Young JANG ; Ho Sang YOON ; Ho Chul CHOI ; Ki Jong SUNG ; Hyun A KIM ; Sung Hee PI ; Hyung Shik SHIN ; Hyung Keun YOU
The Journal of the Korean Academy of Periodontology 2005;35(1):87-98
The purpose of present study was to investigate the effects of physiologically active compound (SD62-122) from Phlomidis Radix on the cell cycle progression and its molecular mechanism in human gingival fibroblasts(HGFs). For this purpose, fibroblasts were isolated and cultured from excisioned gingiva during crown lengthening procedure in healthy adult. The following parameter were evaluated that there are cell number counting, MTT assay, cell cycle progression, western blot analysis. The cell number and MTT assay of primary cultured fibroblast was not increased at 2 days but significant increased compare to negative control at 3days(p<0.05). S phase was increased and G1 phase decreased in both 10(-8)M and 10(-9)M of SD62-122 in cell cycle analysis. The cell cycle regulation protein levels of Cyclin D1, Cyclin E, cdk 2, cdk 4 and cdk 6 were increased compare to control in both 10(-8)M and 10(-9)M of SD62-122. The protein levels of p21 and p53 were decreased compare to control, but the level of pRb was not changed compare to control in 10(-9)M of SD2-122. These results suggested that physiologically active compound (SD62-122) isolated from Phlomidis Radix increases the cell proliferation and cell cycle progression in HGFs, which is linked to increased cell cycle regulation protein levels of Cyclin D1, Cyclin E, cdk 2, cdk 4 and cdk 6, and decreased the levels of p21, p53.
Adult
;
Blotting, Western
;
Cell Count
;
Cell Cycle*
;
Cell Proliferation
;
Crown Lengthening
;
Cyclin D1
;
Cyclin E
;
Cyclins
;
Fibroblasts*
;
G1 Phase
;
Gingiva
;
Humans*
;
S Phase
8.Hemodynamics of Poor-grade Subarachnoid Hemorrhage.
Dal Soo KIM ; Do Sung YOU ; Pil Woo HUH ; Kyung Suk CHO ; Joon Ki KANG
Journal of Korean Neurosurgical Society 1999;28(8):1215-1219
Patients who are devastated neurologically or medically after aneurysmal subarachnoid hemorrhage(SAH) are described as 'poor grade' patients. More recent studies have documented that the initial hemorrhage is by far the most important determinant of outcome after aneurysmal subarachnoid hemorrhage. This review mainly includes hemodynamics and suspected mechanisms of acute brain injury after aneurysmal SAH, particularly in special reference to increased intracranial pressure and cerebral ischemia during and after SAH.
Aneurysm
;
Brain Injuries
;
Brain Ischemia
;
Hemodynamics*
;
Hemorrhage
;
Humans
;
Intracranial Pressure
;
Subarachnoid Hemorrhage*
9.Analgesic Efficacy of Nitrous Oxide During Fracture Reduction in the Emergency Department.
Eun Seog HONG ; Sung Oh HWANG ; Jin Woong LEE ; Sun Man KIM ; Hyun KIM ; Kang Hyun LEE ; Kyoung Soo LIM ; Ki Cheol YOU
Journal of the Korean Society of Emergency Medicine 1997;8(4):584-589
BACKGROUND: induction of analgesia is frequently required during undergoing reduction of fractures or dislocation in the emergency department. METHODto induce analgesia should be easy, convenient, and safe because patients are not always in fasting state. Nitrous oxide inhalation has been known as a good method of analgesia in emergency patients. PURPOSE: This study was aimed to evaluate the efficacy and safety of nitrous oxide analgesia in the emergency department. METHOD: We prospectively studied 34 patients undergone reductions of fractures in the emergency department. Nitrous-oxide was the sole source of analgesia. The Visual Analogue Scale(VAS) was rated by the emergency physician before nitrous oxide inhalation,5 minutes after inhalation and reduction procedures. RESULTS: No complication such as vomiting, respiratory depression, or a change in oxygen saturation resulted from the use of nitrous-oxide. Ninety one percent of patients obtained an analgesic effect. However, 9% of patients did not experience any analgesic effect after inhalation of nitrous oxide. In subgroup analysis for analgesic effect of nitrous-oxide, nitrous oxide provided only partial analgesia for acute pain in open fracture group. VAS was significantly lower after inhalation than before inhalation of nitrous oxide in simple fracture group. However, VAS of simple fracture group was increased during closed reductions, which indicated incomplete relief of pain by nitrous oxide. Nitrous oxide inhalation foiled to relieve pain during reduction in patients with open fracture or dislocation. CONCLUSION: Administration of nitrous-oxide, when used as the sole source of analgesia, is not the ideal method of analgesia during reduction of fractures or dislocations.
Acute Pain
;
Analgesia
;
Dislocations
;
Emergencies*
;
Emergency Service, Hospital*
;
Fasting
;
Fractures, Open
;
Humans
;
Inhalation
;
Nitrous Oxide*
;
Oxygen
;
Prospective Studies
;
Respiratory Insufficiency
;
Vomiting
10.Application of Emergency Transcutaneous Cardiac Pacing in Hemodynamically Unstable Patients with Bradyarrhythmia in the Emergency Department.
Eun Seog HONG ; Sung Oh HWANG ; Kang Hyun LEE ; Jin Woong LEE ; Sun Man KIM ; Hyun KIM ; Jun Hwi CHO ; Kyoung Soo LIM ; Ki Cheol YOU
Journal of the Korean Society of Emergency Medicine 1997;8(4):520-527
Transcutaneous cardiac pacing(TCP) is a rapid, safe, noninvasive and easily utilized form of emergency cardiac pacing, with hemodynamically similar to transvenous cardiac pacing. This paper reports the result of transcutaneous pacing in a series of patients in emergency department.32 patients with bradyanhythmia were enrolled during the study period. TCP was successful in 29(91%) patients. No evidence of electrical capture was seen in two patients in asystole and a patient with ventricular escape rhythm. Mean capture threshold was 66 mA. Transvenous pacemaker was inserted in 18(56%) of the 32 patients during transcutaneous cardiac pacing. Twenty(61%) of the 32 patients survived and eventually discharged. Ten patients(31%) were died of uncorrectable underlying disease in spite of successful ECG capture and palpable pulse by TCP. In conclusion, TCP is a reliable, noninvasive method that offers the possibility to initiate pacing within seconds and can be used by any emergency medical staff. In our opinion, it should be considered as the first choice of emergency treatment of hemodynamically unstable bradyarrhythmia.
Bradycardia*
;
Electrocardiography
;
Emergencies*
;
Emergency Service, Hospital*
;
Emergency Treatment
;
Heart Arrest
;
Humans
;
Medical Staff
;
United Nations