1.Two Cases of Idiopathic pulmonary Hemosiderosis.
Sung Ky YOU ; Ki Soo KIM ; Young Jee KIM ; Young Yull KOH
Journal of the Korean Pediatric Society 1988;31(9):1209-1216
No abstract available.
Hemosiderosis*
2.Antimicrobial activity and combination effect of drugs to vibrio vulnificus.
Tai You HA ; Ki Kon OWN ; Hee Sung WHANG ; Jong Wook PARK
Journal of the Korean Society for Microbiology 1991;26(6):519-530
No abstract available.
Vibrio vulnificus*
;
Vibrio*
3.Reevaluation of the importance of finding rash, lymphadenitis and eschars for the early clinical diagnosis of Tsutsugamushi disease.
Kang Su YI ; Sung Kun YOU ; Wan KO ; Won Young LEE ; Chin Ki PAI ; Ki Il KIM ; Yunsop CHONG
Korean Journal of Infectious Diseases 1991;23(3):163-169
No abstract available.
Diagnosis*
;
Exanthema*
;
Lymphadenitis*
;
Scrub Typhus*
5.Dural Tear and Root Entrapment in Lumbar Burst Fractures.
Byung Joon SHIN ; Sang Ki KIM ; You Sung SUH ; Yon Il KIM ; Soo Kyoon RAH ; Chang Uk CHOI
Journal of Korean Society of Spine Surgery 1997;4(1):98-105
No abstract available.
6.Suspicious Reperfusion Injury of Spinal Cord After Multilevel Cervical Posterior Decompression without Remarkable Surgical Insult: Two Case Reports.
Kyu Yeol LEE ; Sung Gon YOU ; Ki Woong KIM
Journal of Korean Society of Spine Surgery 2014;21(2):97-102
STUDY DESIGN: Two case reports. OBJECTIVES: We present two cases of quadriplegia after posterior decompression with fusion caused by a suspicious reperfusion injury of spinal cord without remarkable surgical insult. SUMMARY OF LITERATURE REVIEW: Posterior decompression and posterolateral fusion have been reported as effective procedures in patients with multilevel myelopathy. However, postoperative spinal cord injury without remarkable intraoperative technical damage has been reported in a few articles. Reperfusion mechanism was suggested as one of the leading causes and reported in some animal models. MATERIALS AND METHODS: There was one case of ossification of the posterior longitudinal ligament and one developmental multilevel stenosis that underwent laminectomy with lateral mass instrumentation. After surgery, the patients presented with quadriplegia; MRI demonstrated swelling of the spinal cord and intramedullary lesion in two cases. RESULTS: After surgery, the patients presented with quadriplegia; MRI demonstrated swelling of the spinal cord and intramedullary lesion in two cases. CONCLUSION: Although patients with such a medical condition are rare, it is difficult to predict postoperative swelling of the spinal cord before surgery. The surgeon should thus be aware of such rare disease conditions involving the spinal cord before the surgical procedure.
Constriction, Pathologic
;
Decompression*
;
Humans
;
Laminectomy
;
Longitudinal Ligaments
;
Magnetic Resonance Imaging
;
Models, Animal
;
Quadriplegia
;
Rare Diseases
;
Reperfusion
;
Reperfusion Injury*
;
Spinal Cord Diseases
;
Spinal Cord Injuries
;
Spinal Cord*
7.Effect of the Physiologically Active Compounds in Phlomidis Radix on Cell Cycle Regulation in Human Gingival Fibroblasts.
Suk Joo YOU ; Kil Young JANG ; Ho Sang YOON ; Ho Chul CHOI ; Ki Jong SUNG ; Hyun A KIM ; Sung Hee PI ; Hyung Shik SHIN ; Hyung Keun YOU
The Journal of the Korean Academy of Periodontology 2005;35(1):87-98
The purpose of present study was to investigate the effects of physiologically active compound (SD62-122) from Phlomidis Radix on the cell cycle progression and its molecular mechanism in human gingival fibroblasts(HGFs). For this purpose, fibroblasts were isolated and cultured from excisioned gingiva during crown lengthening procedure in healthy adult. The following parameter were evaluated that there are cell number counting, MTT assay, cell cycle progression, western blot analysis. The cell number and MTT assay of primary cultured fibroblast was not increased at 2 days but significant increased compare to negative control at 3days(p<0.05). S phase was increased and G1 phase decreased in both 10(-8)M and 10(-9)M of SD62-122 in cell cycle analysis. The cell cycle regulation protein levels of Cyclin D1, Cyclin E, cdk 2, cdk 4 and cdk 6 were increased compare to control in both 10(-8)M and 10(-9)M of SD62-122. The protein levels of p21 and p53 were decreased compare to control, but the level of pRb was not changed compare to control in 10(-9)M of SD2-122. These results suggested that physiologically active compound (SD62-122) isolated from Phlomidis Radix increases the cell proliferation and cell cycle progression in HGFs, which is linked to increased cell cycle regulation protein levels of Cyclin D1, Cyclin E, cdk 2, cdk 4 and cdk 6, and decreased the levels of p21, p53.
Adult
;
Blotting, Western
;
Cell Count
;
Cell Cycle*
;
Cell Proliferation
;
Crown Lengthening
;
Cyclin D1
;
Cyclin E
;
Cyclins
;
Fibroblasts*
;
G1 Phase
;
Gingiva
;
Humans*
;
S Phase
8.Comparison between operative versus non-operative management of traumatic liver injury.
Ki Bum PARK ; Dong Do YOU ; Tae Ho HONG ; Jung Min HEO ; Yong Sung WON
Korean Journal of Hepato-Biliary-Pancreatic Surgery 2015;19(3):103-108
BACKGROUNDS/AIMS: The aim of this study was to compare operative versus non-operative management of patients with liver injury and to ascertain the differences of the clinical features. METHODS: From April 2000 to July 2012, 191 patients were admitted to Seoul St. Mary's Hospital and St. Vincent's Hospital for liver injuries. Of these, 148 patients were included in this study. All patients were diagnosed using computed tomography (CT). The liver injury was graded in accordance with the American Association for the Surgery of Trauma liver injury scoring scale. Patients were divided into two groups: those who underwent surgery and those treated with non-operative management (NOM). There was a comparison between these two groups concerning the clinical characteristics, grade of liver injury, hemodynamic stability, laboratory findings, and mortality. RESULTS: According to the 148 patient records evaluated, 108 (72.9%) patients were treated with NOM, and 40 (27.1%) underwent surgery. Patients treated with NOM had significantly fewer severe injuries as rated using the Revised Traumatic Injury Scale, Injury Severity Score, and Glasgow Coma Scale. Grade of liver injury and number of patients with extravasation of contrast dye on CT and hemoperitoneum were higher in the operative group than in the NOM group. There were significant differences between the two groups for: heart rate, respiratory rate, systolic blood pressure, and mean hemoglobin levels at admission and after 4 hours. The operative group experienced a significantly higher mortality than the NOM group. CONCLUSIONS: The results of our study suggest that hemodynamic stability and the following should be considered for deciding the treatment for liver injuries: grade of liver injury, amount of blood loss, and injury scales scores.
Abdominal Injuries
;
Blood Pressure
;
Glasgow Coma Scale
;
Heart Rate
;
Hemodynamics
;
Hemoperitoneum
;
Humans
;
Injury Severity Score
;
Liver*
;
Mortality
;
Respiratory Rate
;
Seoul
;
Weights and Measures
9.The Impact of Appendiceal CT on Patients with Suggestive Appendicitis.
Jee Man YOU ; Jeung Kyun LEE ; Won Cheul PARK ; Dong Baek KANG ; Sung eun YOON ; Ki Jung YOON
Journal of the Korean Surgical Society 2007;72(2):113-116
PURPOSE: This study was performed to evaluate the contribution of appendiceal computed tomography (CT) in the more accurate diagnosis of acute appendicitis and decrease in the rate of negative appendectomies. METHODS: Between May and August 2005, 146 patients with right lower quadrant (RLQ) abdominal pain and tenderness were diagnosed using appendiceal CT. The appendiceal CT scans were performed with contrast media in the abdominal and pelvic areas. 7 mm slice scans were taken both before and after the contrast media injection, with a time delay. The control group was comprised of 99 patients, who were also checked by abdominal CT or ultrasonography, between December 2004 and April 2005, with the data analyzed retrospectively. RESULTS: In the study group, 85 of the 146 cases were diagnosed with acute appendicitis on appendiceal CT, and had undergone an appendectomy, including 42 men (mean age 39.9 yr) and 43 women (mean age 44.6 yr). The sensitivity and specificity of appendiceal CT in acute appendicitis were 95.3 and 98.4%, respectively. There were 4 (4.7%) negative appendectomy cases; 2 in men and 2 in women. The control group conprised of 47 men and 52 women. There were 13 (13.1%) negative appendectomy cases; 4 in men and 9 in women. CONCLUSION: The routine use of appendiceal CT, in patients with RLQ abdominal pain and tenderness, resulted in a significant decrease in the negative appendectomy rate.
Abdominal Pain
;
Appendectomy
;
Appendicitis*
;
Contrast Media
;
Diagnosis
;
Female
;
Humans
;
Male
;
Retrospective Studies
;
Sensitivity and Specificity
;
Tomography, X-Ray Computed
;
Ultrasonography
10.Sequential bronchoscopic findings of endobronchial tuberculosis.
Hyung Seok CHOI ; Ki Ho JEONG ; Kye Young LEE ; Chul Gyu YOO ; Young Whan KIM ; Sung Koo HAN ; Keun You KIM ; Yong Chol HAN
Tuberculosis and Respiratory Diseases 1992;39(5):407-416
No abstract available.
Tuberculosis*