Female ; Humans ; Mice ; Animals

The infantile cortical hyperostosis is relatively rare unknown cause disease. After the first report of a case of this was that of caffey in 1945, this disease is increasing in frequency. This disease characterized by subperiosteal new bone formation on various bone, leukocytosis, increased Erythrocyte Seidmentation Rate, fever. We experienced two cases of this and reported them in this paper with a brief review of tbe literature.
Erythrocytes ; Fever ; Hyperostosis, Cortical, Congenital ; Leukocytosis ; Osteogenesis

Genomic DNAs were extracted from cervical lavages of 49 patients with cervical cancer. Dot and Southern blot hybridization were performed using the P-labeled HFV DNA probes to find high risk HPV(type 16 and 18) infection that is known as the mast prevalent pathogenic factor in cervical cancer. Furthermore, genornic DNAs purified frnm cervical cancer tissues were studied in 8 out of 49 patients allowing us to convince the results from cervical lavages. The results were as follaws: 1. Dot blot analysis were used to examine the sensitivity and specificity of hybridization condition and HPV-DNA probes. Fasitive signals were obtained even at the level of 10pg for HPV DNA, but no signals could he detected at the level of as much as 400pg for salmon sperm DNA. 2. Dot blot of DNAs from cervircal lavages showed positive signals in 32.7%(16/49) with HPV type 16 probe and 20.4% (10/49)and one mixed infection was found. 3. When the DNAs from cervircal lavages of 49 patients were classified according to the clinical stage of cervical cancer, the infection rates of HPV type 16 and 18 were 50% (2/4) in CIN, 80% (4/5) in stage I, 64. 2% (9/14) in stage I b, 45% (9I20) in stage II and 16. 7% (1/6) in stage Ill and K respectively. The occurrenr,e of HPV type 16 and 18 seemed to be the highest in the cervical cancer stage 1 (68.4%(13/19). 4. Experiments perfornecl with genomic DNAs from 8 cancer tissues showed similar results compared to those of cervical lavages, but the intensity of positive signals was stronger. 5. Genomic DNAs from 5 patients(3 cases from cervical lavages and 2 cases from cervical cancer tissues) which showed strong positive signals to the dot blot analysis were further examined by Southern blot hybridixation using HFV type 16 DNA probe. When DNAs were digested with Pst 1 restriction enzyme, the five characteristic frgmenta of BFV type 16(2.8, l.9, l.6, 1.0 and 0.5 kb long in length) were recognized in ell 5 cases, These results may suggest a direet relatianship between HPV type 16 & 18 infectioas considered as the most effective methods for HPV detectioe and typing. Mo1ecular biclogieal studies in the reserarch of HPV are expected to reveal and help us understand the pathogenesis of cervical cancer.
Blotting, Southern ; Coinfection ; DNA Probes ; DNA* ; Humans* ; Salmon ; Sensitivity and Specificity ; Spermatozoa ; Therapeutic Irrigation ; Uterine Cervical Neoplasms*

Fibronectin(FN) is a physiologic glycoprotein presenton cell surface and in connective tissue, extracellular matrix and plasma. Increased plasma FN levels have been reported in the patients with psoriasis, connective tissue disease, internal malignancy, squamous cell carcinoma and basal cell carcinoma. The author investigated the plasma FN levels in 30 patients (males 13, female 17) with psoriasis and 23 healthy subjects (male 13, female 10) by gelatin sepharose 4B affinity chromatography and Laurells rocket immunoelectrophoresis method. The results were as follows : Plasrna JN levels were 450.4+/-80.3pg/ml in the patients with psoriasis and 334.0-51.3pg/ml in healthy subjects. There was no relationship between age graups and sex. Plasrna FN levels in the patients with psoriasis were higher than those of healthy subjects(p<0.001). There was no relationship between the levels of plasma FN and clinical severity of psoriasis.
Carcinoma, Basal Cell ; Carcinoma, Squamous Cell ; Chromatography, Affinity ; Connective Tissue ; Connective Tissue Diseases ; Extracellular Matrix ; Female ; Fibronectins* ; Gelatin ; Glycoproteins ; Humans ; Immunoelectrophoresis ; Plasma* ; Psoriasis* ; Sepharose

No abstract available.
Drug Therapy* ; Humans

The reference study was performed to describe the trend and characteristics & studies related to dying and death of the elderly. The data were collected from 44 article in foreign literature. There results were as follows: 1. The research subjects related to the ares of dying and death of the elderly were death(death attitude, death anxiety), suicide, morbidity and mortality, dying(ethics at the end of life, right-to-die), and bereavement etc. 2. The selected studies were published in 24 health related Journal, including Journal of the American Geriatrics Society, American Journal of Psychiatry, Japanese Journal of Geriatrics, and International Psychogeriatrics, etc. 3. The published year of the article was between 1992 and 1996. 4. The frequently used research designs were survey, cohort study(retrospective study), records analysis, review, case studies and epidemiologic studies. 5. Questionnaires, medical records, interview, review, case studies, observation, and test were mainly used for the data collection for the selected studies.
Aged* ; Asian Continental Ancestry Group ; Bereavement ; Cohort Studies ; Epidemiologic Studies ; Geriatric Psychiatry ; Geriatrics ; Humans ; Medical Records ; Mortality ; Research Design ; Research Subjects ; Suicide ; Surveys and Questionnaires

BACKGROUND: This study aimed to identify the association of compliance with sick role behavior with satisfaction of basic psychological needs, and to assess the influence of compliance with sick role behavior among hemodialysis patients. METHODS: Participants included 109 patients from outpatient dialysis clinics at 6 major general hospitals located in urban areas in Korea. Data for compliance with sick role behavior and basic psychological needs were collected through a self-reported questionnaire and was analyzed with independent t-test, one-way analysis of variance, Pearson' correlation analysis, and multiple stepwise linear regression analysis. RESULTS: This study showed positive correlations between compliance with sick role behavior and satisfaction of basic psychological needs (r=0.59, P<0.001). The variables predicting compliance with sick role behavior were relatedness (beta=0.28), autonomy (beta=0.29), competency (beta=0.30), and age (beta=0.24). These variables accounted for 38.2% of the variance of compliance with sick role behavior in hemodialysis patients. CONCLUSIONS: Our results indicated that it is necessary to improve compliance with sick role behaviorin order to increase satisfaction of basic psychological needs in hemodialysis patients.
Analysis of Variance ; Compliance ; Dialysis ; Hospitals, General ; Humans ; Korea ; Linear Models ; Outpatients ; Patient Compliance ; Personal Autonomy ; Renal Dialysis ; Sick Role

No abstract available.

No abstract available.
Wounds, Stab*

PURPOSE: This research is to know whether aroma foot massage has influence on the relief of anxiety and pain during colonoscopy under conscious sedation. METHOD: This research was designed as a quasi-experiment of non-equivalent control group pretest-posttest. Data were collected from April 1 2005 to August 30 2005. The subjects were divided into three groups (control group, foot massage group and aroma foot massage group) with 30 persons each. Anxiety was evaluated with Visual Analogue Scale (VAS), blood pressure and pulse. Pain response was measured with VAS and non-verbal pain behavior score. Sleep satisfaction was measured with a graphic rating scale. Data were analyzed through Chi-square test, t-test and repeated measure ANOVA. RESULTS: Systolic blood pressure, pulse, subjective anxiety and pain scores from the aroma foot massage group decreased significantly. Sleep satisfaction score of the aroma foot massage group increased significantly. Diastolic blood pressure from the aroma foot massage group did not decrease. CONCLUSION: The results show that aroma foot massage with refined oils can increase sleep satisfaction and decrease anxiety and pain during colonoscopy under conscious sedation.
Anxiety* ; Blood Pressure ; Colonoscopy* ; Conscious Sedation* ; Foot* ; Humans ; Massage* ; Oils