The Diltiazem hydrochloride is a new calcium antagonist of which effect on angina pectoris has been reported. Authors studied the clinical effect of Diltiazem in 18 cases of angina pectoris including stable and unstable angina. The 14 cases were male and 4 cases were female with ages ranging 46 to 72 years. All cases had typical anginal attack on 1-6 times in everyday with transient improvement by sublingual nitroglycerin. After coutine physical and laboratory work-up, Diltiazem 30mg tablet was given 3 times a day for 3 consecutive weeks and checked the response of angical pain for first 3 times visit with 3 days interval and thereafter with one week interval. In 13 cases of 15 cases, the Diltiazem alone was medicated. There was considerable improvement of anginal attack in 13 cases of 15 cases with Diltiazem alone, namely complete subsidence of anginal attack throughout 3 weeks in 2 cases, only minimal substernal discomfort on effort once a week in 4 cases and in 7 cases the frequency and severity of anginal pain reduced to about 50% of control state. In 2 of 15 cases there were no effect on anginal pain until one week, subsequently a beta-blocker was added and the anginal attack improved considerably in both cases. In 3 cases of 18 cases, the anginal attacks were so severe and frequent that the Diltiazem with beta-blocker were given from the beginning. In one case the anginal pain disappeared completely and in two cases there were good effect. The effect of Diltiazem usually started to occurs in 3 days to one week after medication. The overall effectiveness of Diltiazem in angina pectoris was 87% with excellent effect in 40%, good effect in 27% and fair effect in 20%. In 5 cases of good response to Diltiazem, the stress exercise test by bicycle ergometer was carried out before and after one week medication with programs of 30 wt, 50 wt, 75 wt, and 100 wt loading for 4 minutes in each stage. The exercise tolerance improved about 25-50 wt, the ST depression by exercise became less by 1-2mm and the maximal heart rate increased by 4-9/min. These data showed marked improvement of exercise tolerance in angina pectoris by Dltiazem objectively. There were macular skin rash, diarrhea and mild dizziness in one case respectively which were improved without treatment. These data showed that Diltiazem was highly effective in angina pectoris except few very severe cases. In severe cases, the combined therapy of Diltiazem and beta-blocker was more effective.
Angina Pectoris* ; Angina, Unstable ; Calcium ; Depression ; Diarrhea ; Diltiazem* ; Dizziness ; Exanthema ; Exercise Test ; Exercise Tolerance ; Female ; Heart Rate ; Humans ; Male ; Nitroglycerin

No abstract available.
Candida albicans* ; Candida* ; DNA*

Pemphigus vulgaris is serious mucocutaneous bullous disease and is rarely reported in this country. The authors had observed a patient with pemphigus vulgaris from its early stage to the autopsy, including a total of five admissions. The patient had satisfactorily responded to low doses of prednisolone (60mg/day) initially and high doses (up to 180mg/day) later, but the patient died unexpectedly during admission. Autopsy finding revealed extensive soft tissue abscesses in both gluteofemoral regions from which Pseudomonas aeruginosa was cultured.

In order to evaluate the accurate diagnosis of scabies through exatr.inations of all requred. conditions, the author conducted an observation on 769 cases of scabies at the Department of Dermatology, Kyungpook University Hospital from January, 1962 to Octover, 1973, In 1962 the frequency of the disease appeared to be low but it dramatically rose to 20 or 30 times between 1963 and 1966, again showing an increasing tendency from 1971. The ratio of frequency between male and female was 4.2: 1. Seasonal occurrence of scahics was found to be highest in winter. Infectious rate in the family was 83.3% and incubation period vas estimated from 15 days to 2 months. Acarus scabiei or its ova were found in 46.5% of all cases examined and in patients over 16 years of age. Acarus scabiei or ova were chiefly found in vesicles of the finger web but the ova were also found in the subungual fold of the finger, which is an important site of examination.
Dermatology ; Diagnosis* ; Female ; Fingers ; Gyeongsangbuk-do ; Humans ; Male ; Mites ; Ovum ; Scabies* ; Seasons

No abstract available.
Child* ; Humans ; Infant* ; Intussusception*

No abstract available.
Pyloric Stenosis, Hypertrophic*

No abstract available.
Common Bile Duct*

No abstract available.
Peptic Ulcer Perforation* ; Peptic Ulcer*

Granuloma pyogenicum is a benign vascular tumor, usually about 0.5 to 2cm in diameter. It occurs as a single lesion with few exceptions and consists of pedunulated nodule with a dull red or slightly purplish color. We observed a 29-year old man who had multiple satellite recurrences in the scapular region which developed after excision of a single lesion of granuloma pyogenicum. Histapathologic findings showed many newly formed capillaries that had prominant endothelial cells and showed varying degrees of dilation without appearance of epiderrnal collarette sign. The lesions were much improved by X-ray irradiation.
Adult ; Capillaries ; Endothelial Cells ; Granuloma, Pyogenic ; Humans ; Recurrence

The patient, 18-year-old girl, had a class III malocclusion with the lateral compression of the maxilla due to the premature loss of the canines, mild mandibular prognathism, and mouth breathing habit. The treatment plan consisted of 1) rapid maxillary expansion 2) a period of retention 3) extraction of the first mandibular premolars instead of surgical correction 4) completion of orthodontic treatment with multibanded system. The maxilla was separated in the midline by the application of orthopedic forces via a cemented rapid maxillary expansion device. After 18 months, She gained functional overbite-overjet relationship, good interdigitation of buccal segments, and facial harmony due to the retraction of lower anterior teeth.
Adolescent ; Bicuspid ; Female ; Humans ; Malocclusion* ; Maxilla ; Mouth Breathing ; Orthopedics ; Palatal Expansion Technique ; Prognathism ; Tooth