No abstract available.
Child* ; Herpes Zoster* ; Humans

No abstract available.
Child* ; Herpes Zoster* ; Humans

No abstract available.
Urinary Bladder Neoplasms* ; Urinary Bladder*

No abstract available.
Magnetic Resonance Imaging* ; Osteosarcoma*

BACKGROUND: The survival rate of children with neuroblastoma has been improved over 20 years, excluding the metastatic disease, in which it does not exceed 20% so far. New treatment modalities have been developed to improve the outcome in metastatic disease. Preoperative chemotherapy reduce the size, the vascularity and the adhesiveness, so increase the resectability of the primary tumor. This retrospective clinical study was designed to review the survival rate in neuroblastoma and to analyze the effect of preoperative chemotherapy in the view point of neoadjuvant therapy on long-term survival in advanced disease. METHODS: One hundred and thirty-four cases were reviewed from 135 patients with neuroblastoma registered at the Department of Pediatrics in Seoul National University Children's Hospital from January, 1985 till December, 1995. The survival rate was reviewed according to the stage. The age, sex of the patients, the stage, anatomical site of the tumor, the level of serum ferritin and neuron-specific enolase were analyzed for the risk factors on survival. RESULTS: Ranges of age at diagnosis were from 1 month to 166 months with the median of 39 months. Five year survival rates and five year disease-free survival rates were 100%, 100% in stage 1(n=5), 90.9%, 90.9% in stage 2(n=13), 43.4%, 40.6% in stage 3(n=19), 27.1%, 19.8% in stage 4(n=95) and 100%, 100% in stage 4S(n=2), respectively. In stage 3, five year survival rate was 52.5% in group receiving neoadjuvant chemotherapy, 28.6% in control group(P=0.02). Five year disease-free survival rate was also noted as 48.6%, 28.6% in each group(P=0.02). In stage 4, five year and ten year survival rates were 27.6%, 23.6% in group receiving neoadjuvant chemotherapy, 26.9%, 0% in control group(P=0.02). Five year and ten year disease-free survival rates were 14.3%, 14.3% in group receiving neoadjuvant chemotherapy, 20%, 0% in control group (P=0.11). In univariate analysis, the age, the stage, and the site of primary tumor appeared to affect the long-term survival. CONCLUSION: Neoadjuvant chemotherapy and delayed primary surgery contribute for advance in survival in advanced neuroblastoma via increasing the resectability of the primary tumor.
Adhesiveness ; Child ; Diagnosis ; Disease-Free Survival ; Drug Therapy* ; Ferritins ; Humans ; Neoadjuvant Therapy ; Neuroblastoma ; Pediatrics ; Phosphopyruvate Hydratase ; Retrospective Studies ; Risk Factors ; Seoul ; Survival Rate

No abstract available.
Incidence* ; Leukemia*

No abstract available.
Anal Canal* ; Carcinoma, Squamous Cell*

No abstract available.
Peptic Ulcer*

PURPOSE: To help in the early diagnosis of postoperative infections in lumbar stenosis, attempts were made to evaluate a large number of patients having levels of ESR, CSR and CRP at fixed intervals, following an uncomplicated instrumented posterolateral fusion with wide decompression. MATERIALS AND METHODS: 101 lumbar stenosis patients were included in this study. The levels of ESR, CSR and CRP were checked on the 2nd, 3rd, 4th, 7th, 10th and 14th postoperative days. These data were plotted in relation to time in order to follow their changes. The relationships between these and the perioperative factors (operation time, fusion levels, estimated bleeding amount and transfusion amount) were evaluated statistically. RESULTS: The ESR and CSR had peak levels by the 3rd postoperative day, which then became highly variable until 14 days. The CRP level was highest on the 2nd postoperative day, which decreased rapidly, was and reached nearly normalized levels by 14th day. The ESR and CSR values on the 7th postoperative day showed a tendency to correlate with the perioperative factors, but the CRP value showed no significant correlations. CONCLUSIONS: Our study revealed the effectiveness of CRP, and ineffectiveness of ESR and CSR, in the early detection of deep infections following surgery for wide lumbar stenosis.
Constriction, Pathologic* ; Decompression* ; Early Diagnosis ; Hemorrhage ; Humans

Early diagnosis of persistent abnormal reflexes may be of great significance to a more effective functioning of the cerebral palsied child. It is important to know the normal and abnormal reflex responses and their effect upon motor development for providing a basis for evaluation in the diagnosis and treatment of the cerebral palsied child. We studied 28 cerebral palsied children, between 1 to 12 years old, who were treated at Sam Yook Childrens Rehabilitation Center from May 1975 to December 1977. The pathologic reflexes were checked, and the relationship between pathologic reflexes and walking was compared. The following results were obtained. 1. The following were the most important pathologic reflexes in non-walking fgroup: a. Positive supporting reaction b. Protective extensor thrust c. Moro reflex 2. If they are present, the prognosis for walking ambulation was bad and surgery will not improve for the chances of walking.
Child ; Diagnosis ; Early Diagnosis ; Humans ; Prognosis ; Reflex ; Reflex, Abnormal ; Reflex, Startle ; Rehabilitation Centers ; Walking