The purpose of this study was to compare shear bonding strengths and debonding patterns of the ceramic brackets attached on the crystal which were grown on the enamel surface of a tooth with different concentrations of lithium sulphate-contained polyacrylic acid in different application times. Four kinds of concentrations of mixed solutions were made and applied to the enamel surface on extracted human premolars. The solutions were made by adding 0.3M or 0.6M of lithium sulfate to 50% or 65% of polyacrylic acid with 0.3M sulfuric acid. The solutions were applied for 30 or 60 seconds. After bonding, a universal testing machine was used to measure the shear bond strength, and then observations were made of debonding patterns through the stereoscope. And the enamel surface was observed through the scanning electron microscope to examine the pattern of crystal growth and debonding. The results were as follows: 1, Shear bond strength in the enamel surface treated with 50% polyacrylic acid was higher than that with 65% polyacrylic acid. 2. There were no statistical differences in shear bond strength according to concentration of lithium sulfate and application time of solutions. 3. Enamel surface was almost free of resin debris after debonding. 4. Enamel surface treated with 50% polyacrylic acid showed higher density of crystal growth than that with 65% polyacrylic acid under scanning electron microscope.
Bicuspid ; Ceramics ; Crystallization* ; Dental Enamel ; Humans ; Lithium* ; Sulfur ; Tooth

The intramedullary nailing is the effective device now available for patient with appropriate fracture of the femoral shaft in adulthood. But problems with shortening and rotation of the femur persist, especially in comminuted fracture of the femoral shaft. So, the fixation with proximal and distal screw was performed. The Brooker-Wills nail achieves distal fixation easily with a transverse fixator deployed through slot in the nail. 24 patients with 25 femoral shaft fractures who treated at Dept. of Orthopaedic Surgery, Ewha Womans University Hospital from April, 1987 to April, 1988 were clinically analysed and the results were as follow. l. Among 25 cases, 22 cases were male and 3 cases were female. Average ages were 35.3 years and 3rd decade was more prominent. 2. 25 cases were classified according to the Winquist-Hansen classification. The Grade II was most common in 20 cases(80%). 3. 18 cases were treated by closed method and 7 cases were treated by open method. The closed method was required for 1.8 hours and open method was required for 2.2 hours. 4. The average time of union of Grade II was most shortened(11 weeks) and Grade IV was most delayed(16 weeks). 5. The complications were non-union in 1 case, mild angulation in 3 cases and limitation of motion of knee joint in 2 cases. So the accurate anatomical reduction and nailing to just above the epiphyseal scar in the metaphysis will be decreased of any complications.
Cicatrix ; Classification ; Female ; Femur ; Fracture Fixation, Intramedullary ; Fractures, Comminuted ; Humans ; Knee Joint ; Male ; Methods

Since ossification of posterior longitudinal ligament in cervical spine (O.P.L.L.) was presented at first by Tsukimoto in 1960, many cases have been reported in Japan. But very few cases were reported outside of Japan, including Korea. It is yet unknown what mechanism is the cause and why it is prevalent among the Japanese. And so, there are various theories on the cause. With progression, this lesion cas cause cervical myelopathy and radiculopathy. The treatment of O.P.L.L. is divided into conservative and operative treatment, and the latter is composed of anterior fusion,anterior decompression and posterior decompression. We experienced 3 cases of O.P.L.L. of which two cases were treated by anterior fusion and one tred by anterior decompression with partial removel of ossification mass from March, 1985 to May, 1986. On the follow-up, results were excellent to good. We report our experience in treatment of O.P.L.L. and recommand to be concerned about the lesion.
Asian Continental Ancestry Group ; Decompression ; Follow-Up Studies ; Humans ; Japan ; Korea ; Longitudinal Ligaments ; Ossification of Posterior Longitudinal Ligament ; Radiculopathy ; Spinal Cord Diseases ; Spine

PURPOSE: The aim of this study was to quantitatively assess the intensity of tumor budding in rectal carcinoma and to determine how it correlates with the malignant potential. MATERIALS AND METHODS: Intensities of the tumor budding at the invasive front of the surgical specimens from 90 patients (male, 51) with well- or moderately- differentiated rectal carcinoma were investigated. Differences in the budding intensity among pathologic variables were compared, and recurrences and survivals were analyzed in accordance with degree of the budding intensity. The patients ranged in age from 33 to 75 years (mean, 55.4) with the median follow-up being 43 months (range, 12~108). RESULTS: Tumor budding was identified in 89 patients (98.9%) with a mean intensity of 7.5+/-5.3. The budding intensity was significantly higher in tumors with lymphatic invasion (p=0.0081), blood vessel invasion (p<0.0001), and perineural invasion (p=0.0013) than in those tumor without these findings. It became significantly higher with the increase in nodal stage (p<0.0001). The intensity of tumor budding in patients with relapse (29 patients) was significantly higher than that in patients without relapse (6.2+/-5.0 vs. 10.2+/-4.9; p=0.0005), but this difference in the intensity was observed only for the node-positive patients (8.0+/-3.4 vs. 11.9+/-5.1; p=0.0064). When the patients were stratified into two groups on either side of the mean of the intensity, the higher intensity group showed a significantly less favorable disease- free (DFS) and overall survival (OS) (p=0.0026 and 0.0205, respectively). Based on the multivariate analysis, the nodal stage and the intensity of budding proved to be the independent variables associated with DFS (p=0.023 and 0.03, respectively). CONCLUSION: Tumor budding at the invasive margin is a reliable pathologic index that indicates a higher malignant potential and a less favorable prognosis for patients with advanced rectal carcinoma.
Blood Vessels ; Follow-Up Studies ; Humans ; Multivariate Analysis ; Prognosis ; Recurrence

PURPOSE: The aim of this study was to evaluate the prognostic significance of the ratio between metastatic and examined lymph nodes (LNs) in patients with stage III rectal cancer. METHODS: A review was made of 175 (male, 98) patients with stage III rectal cancer of R0 resection. LN disease was stratified both by the American Joint Committee on Cancer/International Union Against Cancer nodal classification (pN) and by quartiles of the lymph node ratio (LNR). Disease-free survivals (DFS) were made using Kaplan-Meier curves and assessed by the log rank test and multivariate analysis was performed using the Cox proportional hazards model. RESULTS: Patients ranged in age from 29 to 83 (median, 60) years with median follow-up of 47 months (range, 13 to 181 months). months. There was a significant correlation between the number of metastatic LNs and the LNR (r = 0.8681, P < 0.0001). Cut-off points of LNR quartiles best to separate patients with regard to 5-year DFS were between quartile 2 and 3, and between 3 and 4 (LNR1, 2, and 3); the 5-year DFS according to such stratification was 89.6%, 55.8%, and 18.2% in LNR1, 2, and 3, respectively (P < 0.0001). Cox model identified the LNR as the most significant independent prognostic covariate; LNR2 showed 3.6 times (95% confidence interval [CI], 1.682 to 7.584; P = 0.0009) and LNR3, 18.7 times (95% CI, 6.872 to 50.664; P < 0.0001) more risky than LNR1. CONCLUSION: This study suggests that ratio-based LN staging, which reflects the number of LNs examined and the quality of LN dissection, is a simple and reliable system for prognostic LN stratification in patients with stage III rectal cancer.
Disease-Free Survival ; Follow-Up Studies ; Humans ; Joints ; Lymph Nodes ; Multivariate Analysis ; Rectal Neoplasms

Palmoplantar lichen planus is a rare, localized variant of the disease that may create difficulty in diagnosis if it is present as an isolated finding. As palmoplantar lichen planus do not usually have the classically clinical features of lichen planus, a biopsy is very useful. Histopathologic findings are identical to classic lichen planus. According to literature, similar lichen planus may be found elsewhere on the body in palmoplantar lichen planus. We report a case of lichen planus limited to the soles in a 50 year-old female, who presents with erythematous hyperkeratotic crusted pruritic plaques on both soles.
Biopsy ; Diagnosis ; Female ; Humans ; Lichen Planus* ; Lichens* ; Middle Aged

Granulocyte colony-stimulating factor (G-CSF) is a hematopoietic growth factor (HGF) with many applications in cancer therapy. Many cutaneous adverse reactions associated with G-CSF have been reported in recent years, including injection site reactions, pyoderma gangrenosum, Sweet's syndrome, cutaneous leukocytoclastic vasculitis, and widespread folliculitis. We report a case of vasculitis with atypical myeloid cell induced by G-CSF on the lower extremities
Folliculitis ; Granulocyte Colony-Stimulating Factor* ; Granulocytes* ; Lower Extremity ; Myeloid Cells* ; Pyoderma Gangrenosum ; Sweet Syndrome ; Vasculitis ; Vasculitis, Leukocytoclastic, Cutaneous

Morphea is a rare, sclerotic connective tissue disorder and is thought to be caused by a decreased collagenase activity. Numerous treatment modalities have been tried, such as infiltration with glucocorticosteroid, D-penicillamine, antimalarial agents and cyclosporine. However, all have shown only limited success. We report a case of a 21 year- old female with localized scleroderma, who showed a marked improvement after localized therapy with high dose UVA-1.
Antimalarials ; Collagenases ; Connective Tissue ; Cyclosporine ; Female ; Humans ; Penicillamine ; Phototherapy* ; Scleroderma, Localized*

No abstract available.
Breast Neoplasms* ; Breast* ; Lymph Node Excision* ; Lymph Nodes* ; Mastectomy, Segmental* ; Radiotherapy*

BACKGROUND AND OBJECTIVES: This study was designed to compare the clinical outcomes according to surgical approach of extranasal, endonasal endoscopic, and a combined approach of the two, suggesting the indication of each surgical approach for excision of sinonasal inverted papilloma (IP). SUBJECTS AND METHOD: Fifty-six IP patients who had been operated at the department of Otorhinolaryngology, Pusan National University Hospital from January, 1995 to March, 2001 were retrospectively assessed. The patients were arbitrarily divided into three groups such as excision through extranasal approach (EEA), endonasal endoscopic excision (EEE), and EEE combined with Caldwell-Luc's approach (EEE+C-L) group. RESULTS: The most commonly affected sites by CT/MRI preoperatively was the nasal cavity followed in the decreasing order of frequency by maxillary, ethmoid, sphenoid, and frontal sinus. In the EEA group, the originated sites were the nasal cavity (2/6), maxillary (1/6), and frontal sinus (2/6). In the EEE group, the origin sites by operative findings were the nasal cavity (30/41), maxillary (5/41), sphenoid (3/41), and ethmoid (2/41) sinus. In the EEE+C-L group, eight cases (8/9) originated from the maxillary sinus. There were six cases associated with malignant tumors, five synchronous and one metachronous, treated combined with radiotherapy and/or chemotherapy. A total of eight cases recurred during the follow-up period. The recurrence rate was 16.6% (1/6) in EEA, 14.6% (6/41) in EEE and 10.1% (1/9) in EEE+C-L group, and there was no significant difference according to surgical approaches. CONCLUSION: EEE yielded a successful outcome only when the IP was limited to the originating sites of nasal cavity, medial and upper wall of maxillary sinus, ethmoid sinus, and sphenoid sinus. The complete removal of the tumor by EEE alone could not be achieved when the tumor was originated from the anterior, inferior, and posterolateral wall of maxillary sinus, requiring application of C-L's approach at the same time. EEA can be used with more benefits than EEE when the tumor is originated from the frontal sinus or when the mass tends to invade extensively.
Busan ; Drug Therapy ; Endoscopy ; Ethmoid Sinus ; Follow-Up Studies ; Frontal Sinus ; Humans ; Maxillary Sinus ; Nasal Cavity ; Otolaryngology ; Papilloma, Inverted* ; Paranasal Sinuses ; Radiotherapy ; Recurrence ; Retrospective Studies ; Sphenoid Sinus