Panax ginseng C.A. Meyer (Araliacea) has been known for thousands of years in the Far East as a remedy effective against a multitude of ailments. Pharmacological investigations have shown that the basic effect in ginseng action is its capacity to increase nonspecific resistance of the organism to various untoward influences. Ginseng saponin has been considered the active principle for ginsengs most therapeutic properties. Recently, the use of cream and soap with ginseng extract has been gradually increasing. The purpose of this study is to evaluate the efficacy of Panax ginseng to Candida albicans in vitro. During this experiment ginseng saponin and powder of Panax ginseng root were diluted serially in Sabouraud's dextrose agar, and candidial suspensions of isolated strains from candidial intertrigo and female genitalia were inoculated into each medium containing different concentrations of test materials. Then their growth was observed for weeks at 25'C. After that we measured the size of colonies grown in various concentrations and eompared them with those of the Sabourauds dextrose media. For the complementary study Candida albicans strain isolated from vagina were plated on both Sabouraud's dextrose media and 80 mg/cc ginseng root powder. Microscopic examination, germ tube test and sugar fermentation test were then performed to compare the production of budding cells, the growth of pseudo-hyphae and the characteristics of the yeast on each media. Results from this study show that ginseng saponin and roots of Panax ginseng have no significant effect on growth and multiplication and the characteristics of Candida albicans in vitro.
Female ; Humans

No abstract available.
Retrospective Studies* ; Ribs* ; Transplants*

In order to compare the clinical results of Automated Lamellar Keratoplasty with Laser Assisted In Situ Keratomileusis for corection of high myopia, the effects of the procedure on 9 patients(10eyes) following ALK and 14 patients(15 eyes) following LASIK who were followed up at least 6 months were analyzed retrospectively. Mean preoperative spherical equivalent(S.E) was -17.32D(-11.50D~-22.50D) in ALK group and -16.05D(-12.00D~-24.00D) in LASIK group, while mean postoperative S.E was -3.19D at 1 week, -3.50D at 1 month, -4.12D at 3 months, -3.83D at 6 months in ALK group and +2.10D at 1 week, 0.70D at 1 months, -0.10D at 3 months, -0.58D at 6 months in LASIK group. Mean preoperative uncorrected visual acuity was 0.03 in ALK group and 0.04 in LASIK group. At postoperative 6 months, mean uncorrected visual acuity was improved to 0.18 in ALK group and 0.52 in LASIK group. The percentages of patients achieving correction within +/-1.00D at 6 months were 20% in ALK group and 47% in LASIK group. Postoperative cylindrical change was not significant in each group(p>0.05) and also best corrected visual acuity did not show statiscally significant changes in each group(p>0.05). The complications included folds of corneal flap, increased IOP, night halo, and corneal haze. In conclusion, ALK, when performed for high myopia with Ruiz normogram, resulted in undercorrection. LASIK seems to be much more predictable and accurate than ALK in high myopia.
Corneal Transplantation* ; Humans ; Keratomileusis, Laser In Situ ; Myopia* ; Retrospective Studies ; Visual Acuity

To assess the nutritional and health status of the elderly, anthropometric measurements and blood test for analyzing biochemical indices were carried out from August to September in 1996. Data on the incidence of a specific disease and clinical symptoms were also collected by interviews with a questionnaire. Among the total of 169 free-living elderly interviewed(91 men, 78 women), 86 elderly(57 men, 29 women) participated in the anthropometric measurements, and 73 elderly(52 men, 21 women) in blood tests. Average heights and weights were much lower than the standards established in the Korean Recommended Dietary Allowances. While average triceps skinfold thickness of men and women were above the 50 percentile of the reference data, mid-arm muscle circumferences were lower than the 50 percentile. Prevalences of anemia, assessed by hemoglobin using WHO definition, were 38.5% for men and 33.3% for women. Blood levels of total protein and albumin were above the normal limit for all participants. Mean blood cholesterol levels of men and women were 163.9mg/dl and 185.8mg/dl, and triglyceride levels were 138.2mg/dl and 161.9mg/dl, respectively. Women older than 75 years generally had high levels of BMI, total cholesterol and triglyceride. Health status assessed by clinical symptoms generally showed no significant difference by age, and their smoking, and drinking habits. Males and the elderly who exercised regularly had better health status. It was suggested that exercise was a good way to improve health status.
Aged* ; Anemia ; Cholesterol ; Chungcheongbuk-do* ; Drinking ; Female ; Hematologic Tests ; Humans ; Incidence ; Male ; Nutritional Status* ; Prevalence ; Recommended Dietary Allowances ; Skinfold Thickness ; Smoke ; Smoking ; Triglycerides ; Weights and Measures ; Surveys and Questionnaires

Verrucous carcinoma, a distinct variant of well differentiated squamous cell carcinoma, was originally described as an entity by Ackerman. This histologically benign lesion features relentless local growth and little tendency to metastasize. The commonest location of verrucous carcinoma is the oral cavity. Less frequently, the tumor originates in the squarnous mucosa, skin of the genitalia(glans penis, vulava, vagina, scroturn and perineum), nasal fossa, the larynx or the sole. Now we report a case of verrucous carcinoma developed on the retroauricular area in a 49-year-old man. He was treated by surgical excision followed by skin graft. This appears to be the first reported case arising on the retroauricular area.
Carcinoma, Squamous Cell ; Carcinoma, Verrucous* ; Humans ; Larynx ; Male ; Middle Aged ; Mouth ; Mucous Membrane ; Penis ; Skin ; Transplants ; Vagina

No abstract available.
Child* ; Down Syndrome* ; Humans

Befunolol hydrochloride is a B-adrenergic receptor antagonist cornnory used topically in treatment of glaucoma because of a satisfactory intraocular pressure lowering apcity without relevant topical or systemic side effects. We repart herein a case of allergic contact dermatit.is due to befunc ol nydrochloride in 0.5% Bentos eyedrops, A 52-year-old Korean woman had suffered from erythemanedema with itching sensation on her left eye since Novembeir 18, 1992. She had used various ophtalrnic preparations including Bentos eyedrops containing befinolol hydrochloride 0,5% as its activ cinstituent since October, 1992 for treatment of glaucoma of her left eye. Patch test with the European standard series, rubber series, the patiants eyedrops and their individual constituents showed positive. reactions only to 0.5% Bentos eyedrops(as is) and to befunolol hydrochloride. We noted rapid improvement of skin lesions and syipsms after the withdrawal of Bentos eyedrops and applicatior of another B-blocker(carteolol hydrocilcide).
Dermatitis, Allergic Contact* ; Female ; Glaucoma ; Humans ; Intraocular Pressure ; Middle Aged ; Ophthalmic Solutions* ; Patch Tests ; Pruritus ; Rubber ; Sensation ; Skin

This study was conducted to evaluate the postnatal changes of serum creatine kinase (CK) and its isoenzymes in normal and asphyxiated newborns. In normal newborns total CK, CK-MM and CK-MB reached a plateau between 2 and 24 hr after birth whereas the serum CK-BB remained stable after birth. CK-MM, CK-MB and CK-BB respectivily composed 90~94%, 5~7% and 1~5% of total CK during study period. In asphyxiated newborns total CK, CK-MM and CK-MB reached maximal value at 12 hr after birth whereas CK-BB decreased after birth. There were no significant differences between normal and asphyxiated newborns in total CK, CK-MM and CK-MB during study period (up to 24 hrs after birth). But CK-BB of asphyxiated newborn was elevated significantly (p<0.05) within 6 hrs after birth compared to normal newborns. There were no significant differences of CK and its isoenzymes between patients evaluated by 5 min Apgar scores(0~3, 4~6 and 7~10) or degree of HIE (HIE stage 0~I, II and III). According to these results, the serum CK-BB is elevated in asphyxiated newborns during 1st 6hrs after birth but has no predictive values of the extent of cerebral damage.
Creatine Kinase* ; Creatine* ; Humans ; Infant, Newborn* ; Isoenzymes ; Parturition

Analyzing HI tests of 110 cases of clinical Japanese Encephalitis in 1982, the following results are obtained. 1. The results of HI test are positive in 39 (35.5%), borderline positive in 19 (9.1%), negative in 14 (12.7%) and undetermined in 47 (43.7%) cases. 2. In 49 cases of positive HI test, 14 cases reveal the positive result on the first HI test requested in 5-27 days after the clinical onset of symptoms, and 35 cases show increasing HI titers on the follow-up studies. There is a tendency of increasing HI titers upto 3-4 weeks of onset and sustaining the value for more than two months. 3. In 35 cases with increasing titers on follow-up study, the highest titer is 1:80 in 5 cases, and the half of HI negative cases maintain that value throughout the course. 4. There is no significant statistical differences in clinical characteristics, laboratory and cerebrospinal fluid studies between the patient group of HI positive or borderline and group of HI negative or undermined, except mean hospital day and incidence of coma and death.
Cerebrospinal Fluid ; Coma ; Encephalitis, Arbovirus* ; Encephalitis, Japanese ; Follow-Up Studies ; Hemagglutination Inhibition Tests* ; Hemagglutination* ; Humans ; Incidence ; Korea*

No abstract available.
Candida* ; Granuloma*