A 10 month-old female visited our out-patient clinic, whose chief complaint was an enlargement of right eyeball since 5 month ago. Her physical examination disclosed Cafe-au-lait spots on abdomen and back and a tumor-like mass was seen on right vitreous cavity by slit lamp biomicroscopy, indirect ophthalmoscopy, and orbit CT. The working diagnosis was either neurofibromatosis or retinoblastoma, but choroidal hemangioma was also another possibility tomographically. However, MRI suggested the possibility of choroidal malignant melanoma unexpectedly. Subsequently the eye was enucleated and the tumor was confirmed to be a choroidal malignant melanoma. We report this interesting case and the other case of choroidal malignant melanoma diagnosed by MRI in 57 year-old male.
Female ; Humans ; Hemangioma

No abstract available.
Child* ; Humans

No abstract available.
Child* ; Dermatoglyphics* ; Down Syndrome* ; Humans ; Karyotype*

No abstract available.
Arthrogryposis* ; Humans ; Siblings*

No abstract available.
Blood Transfusion* ; Female ; Humans

BACKGROUNG AND OBJECTIVES: It was reported that low molecular weight heparin (LMWH) was more effective than unfractionated heparin in patients with acute coronary syndrome. Recent studies have shown that the pathophysiology of restenosis in stented lesions was different from those of nonstented lesions. Treatment strategies designed to limit cellular proliferation that were ineffective in nonstented lesions may be efficacious in reducing in-stent restenosis. This study was aimed to compare the clinical and angiographic results of LMWH (nadroparin) after coronary stenting with those of conventional ticlopidine regimen. MATERIALS AND METHODS: Patients were eligible for inclusion if they had angina and/or objective evidence of myocardial ischemia, and a significant (>50%) stenosis that was documented on a recent coronary angiogram. After stenting, prospective randomized comparison study was performed. Patients were randomly assigned to either nadroparin (200 IU/kg, sc, bid) or ticlopidine (250 mg bid) plus aspirin (200 mg qd) treatment groups. Repeat coronary angiography (KERN=*)was performed at 236+/-90days after stenting, and quantitative coronary angiographic analysis (QCA) was done. RESULTS: Intracoronary stent implantation was performed in eighty five lesions in eighty one patients (ticlopidine:40, nadroparin:41). There was no significant difference in any baseline clinical/angiographic variables between the two treatment groups. There were no subacute stent thrombosis, infarction and death in both groups. Six-month event-free survival was 36 (90%) in the ticlopidine group and 35 (85.4%) in the nadroparin group. Follow-up quantitative angiographic data such as late loss (1.35+/-0.70 vs 1.32+/-0.69), loss index (0.53+/-0.70 vs 0.56+/-0.23) and restenosis rate (36% vs 25.8%) were not different between ticlopidine and nadroparin groups. CONCLUSION: Effects of nadroparin were not different from those with ticlopidine therapy in the prevention of restenosis and subacute stent thorombosis after coronary stenting. Clinical outcomes between two strategies were similar. Low molecular weight heparin may be an alternative to ticlopidine in patients that ticlopidine cannot be administered because of severe adverse effects.
Acute Coronary Syndrome ; Aspirin ; Cell Proliferation ; Constriction, Pathologic ; Coronary Angiography ; Disease-Free Survival ; Follow-Up Studies ; Heparin ; Heparin, Low-Molecular-Weight ; Humans ; Infarction ; Myocardial Ischemia ; Nadroparin* ; Prospective Studies ; Stents* ; Thrombosis ; Ticlopidine*

No abstract available.

In 1,146 term neonates without perinatal problems who were born in Kwangju Christian Hospital, blood TSH levels were measured by immunoradiometric assay. In 397 term neonates among them, blood T4 levels were measured by radioimmunoassay in same specimens. 1) In normal neonates aged 3~5 days, 6~10 days, 11~20 days and 21~28 days, the TSH levels were 8.88+/-5.21(mean+/-SD), 9.44+/-5.16, 9.69+/-4.98, 11.96+/-3.75 IU/ml and the T4 levels were 11.41+/-2.79, 11.37+/-2.82, 11.19+/-2.63, 10.51+/-2.99 g/dl respectively. 2) No significant sex difference in TSH level was found in each age group, and TSH level did not correlate with birth weight. In neonates delivered by Cesarean section, TSH levels were lower than those of the normally delivered. 3) T4 levels did not differ between both sexes, and between types of delivery in each age group, and nor did it correlate with birth wweight 4) If the recall rate should be set at 0.2% of the total, TSH levels above 26.9 IU/ml would be required to recall for serum sampling. TSH level above 2 SD was 19.7 IU/ml. Cutoff points of T4 levels at 1.5 SD and 2 SD were 5.8 and 7.2 g/dl respetively, and the lowest 10th percentile was 7.4 g/dl.
Birth Weight ; Cesarean Section ; Female ; Gwangju ; Humans ; Immunoradiometric Assay ; Infant, Newborn* ; Mass Screening* ; Parturition ; Pregnancy ; Radioimmunoassay ; Sex Characteristics

We observed 233 twins and 2 triplets cases among 16,774 newborns delivered at Kwangju Christian Hospital during 5 years from Jan, 1986 to Dec. 1990. The results obtained are as follows: 1) The overall incidence of win pregnancy was 1:72(1.4%)and that of triplets 1:z8387(0.01%). 2) The average male-female sex ratio of twins was 1.06:1 with male predominating and 86% were same sex pairs(male-male 43.8%, female-female 41.3%), only 14.0% being different. 3) The incidence of twin delivery tended to be more prevalent in primigravidas. 4) More than half of all cases(248/466)had birth weight less than 2,500 g, with 33% falling into the range of 2,001~2,500 g. No statistically significant differences of birth weight were noted between both sexes or among birth sequences. 5) At 5 minute after birth, Apgar score below 7 were found in 9.5% of the firtst born and in 11.6% of second born twins, with no significant difference noted. 6) The perinatal mortality rate of twins were 94.4/1,000 and the perinatal mortality rates of first and second twins were 77.2 and 111.6, resp., but not significantly different. The larger the difference of birth weight between co-twins, the shorter thee gestational age and the less the birth weight between co-twins, the shorter the gestation age and the less the birth weight of twins, the larger became the perinatal mortality. But, it was not related to the parities or maternal ages. 7) The overall principal causes of perinatal death were still birth (45.5%), respiratory distress syndrome(36.4%) and immaturity(11.4%) in descending order.
Apgar Score ; Birth Weight ; Gestational Age ; Gwangju ; Humans ; Incidence ; Infant, Newborn ; Male ; Maternal Age ; Parturition ; Perinatal Mortality ; Pregnancy ; Sex Ratio ; Triplets ; Twins*

No abstract available.
Barium* ; Intussusception*