1.Four Patients with Culture Negative, Afebrile Infective Endocarditis Who Mainly Showed Immunologic Phenomena.
Ki Kwon LIM ; Jee Hyuk PARK ; Jeong Euy PARK ; Dae Won KIM ; Kap No LEE
Korean Circulation Journal 1987;17(4):771-775
A total of 33 patients with infective endocarditis were observed in the Guro and Hye Hwa Hospitals of Korea University Between September, 1981 and Feb, 1987. Among thses patients four patients presented with heart murmur and heart failure and had vegetation like findings observed on the two dimensional echocardiography. But these patients did not have any fever or leukocytosis in the peripheral blood and the repeated blood cultures were negative. They showed the immunologic phenomena of infective endocarditis such as microscopic hematuria in 4 patients, rheumatoid factor in 3 patients, false positive VDRL in one patient. The serum complement was decreased in 2 patients in whom it was checked. We report these 4 patients because we think these patients might be in the clinical stage in which the infecting organism is spontaneously cleared but the immunologic sequelae are remained.
Complement System Proteins
;
Echocardiography
;
Endocarditis*
;
Fever
;
Heart Failure
;
Heart Murmurs
;
Hematuria
;
Humans
;
Korea
;
Leukocytosis
;
Rheumatoid Factor
2.Effects of age, sex, and body mass index on sudomotor and cardiovagal functions in a healthy Korean population
Heejeong Jeong ; Ki-Jong Park ; Heeyoung Kang ; Nack-Cheon Choi ; Oh-Young Kwon ; ByeongHoon Lim
Neurology Asia 2016;21(3):255-260
Background: Hypertension results from an impaired baroreceptor reflex and enhanced sympathetic
activity. The prevalence of hypertension differs among ethnicities and is more frequent in South Asians
than in Caucasians, suggesting that baseline autonomic nervous system functions and their regulation
may also differ among ethnic groups. In most studies, the reference values for clinical autonomic
function tests are obtained from heterogeneous ethnic populations, or ethnic factors are not considered
in the study design. Obtaining reference data in a homogenous ethnic group and comparing them within
various ethnic groups could be helpful to detect ethnic differences in autonomic functions. The aim of
this study was to identify normative reference values for standard autonomic reflex measurements in
a homogeneous Korean population. Methods: A total of 181 healthy Korean volunteers (age, 20–74
years) underwent standard autonomic function tests: heart rate difference during deep breathing,
Valsalva maneuver, and the quantitative sudomotor axon-reflex test. Mean and 5th and 95th percentile
values were obtained for each age group. We also analyzed factors (age, sex, and body mass index)
that can influence autonomic functions. Results: The heart rate difference during deep breathing and
expiratory-inspiratory ratio were higher in males than in females and were inversely related to age.
The Valsalva ratio was inversely related to age. Males had higher sweat volumes at all body areas
evaluated than those of females, and only forearm sweat volume was significantly different between
the age groups.
Conclusions: Cardiovagal function was affected by age and sex in Koreans. Sudomotor function was
affected by sex, and only forearm sweat volume was affected by age and sex. These results represent
preliminary normative clinical autonomic data in a Korean population comprised of a single ethnicity
Hypertension
3.Value of Tip/Base Rgidity Activity Unit on Interpretation of Nocturnal Penile Tumescence & Rigidity Monitoring.
Won Jae YANG ; Sang Kwon BYON ; Woo Young KI ; Heon Gwan LIM ; Woong Hee LEE ; Hyung Ki CHOI
Korean Journal of Urology 2000;41(11):1389-1393
No abstract available.
Male
;
Penile Erection*
4.Studies on expression of DNA topoisomerases genes and protooncogene c-Myc during hepatocarcinogenesis.
Byung Doo HWANG ; Sang Hee WON ; Ki Ryang KWON ; Kye Young KIM ; Dae Young KANG ; Sang Tae KWAK ; Kyoo LIM
Journal of the Korean Cancer Association 1993;25(5):636-650
No abstract available.
DNA Topoisomerases*
;
DNA*
5.The Effect of Bacterial Lipopolysaccharide on the Lymphokine Production of the T Lymphocytes.
Hyung Bae MOON ; Ki Jung YUN ; Won Chul HAN ; Chae Woong LIM ; Hyuk Nyun KWON ; Young Soon PARK
Korean Journal of Pathology 1997;31(3):244-251
It is well known that the murine T helper cell clones are divided by their lymphokine secretory activities. One is the Th-1 cell, producing IL-2 and IFN after stimulation and the other is the Th-2 cell, producing the IL-4 and IL-5. This study was undertaken to evaluate the immunomodulatory properties of the bacterial lipopolysaccharide(LPS) on the lymphokine production in vivo and in vitro. The results were as follows: There were no effects on the lymphokine secretion by the in vitro treatment of the LPS. The in vivo treatment of the LPS decreases the capability of the production of IL-2 and IFN , whereas it increases the capability of IL-4 production. The altered capacity of the lymphokine production was recovered about 2 weeks after the treatment of the LPS. There were no differences on the lymphokine production between E-coli LPS and salmonella LPS. The capacity of the lymphokine production was the same in the treatment of a non-heated LPS or heated-LPS. The lymphokine production of the mice which were desensitized by the long term treatment of the LPS was not different from the control mice. The in vitro treatment of RU486 can block the alterations of the lymphokine production after the treatment of the LPS. In summary, one can tell that the LPS increases the secretion of the IL-4 through the endogenous secretion of the glucocorticoids.
Animals
;
Clone Cells
;
Glucocorticoids
;
Interleukin-2
;
Interleukin-4
;
Interleukin-5
;
Mice
;
Mifepristone
;
Salmonella
;
T-Lymphocytes*
;
T-Lymphocytes, Helper-Inducer
6.The Clinical Analysis of Patients with Carpal Tunnel Syndrome Underwent Surgery: Comparison Between Conventional and Endoscopic Surgery.
Yung Jun KWON ; Tae Sung KIM ; Young Jin LIM ; Bong Arm RHEE ; Won LEEM ; Gook Ki KIM
Journal of Korean Neurosurgical Society 2000;29(3):372-378
No abstract available.
Carpal Tunnel Syndrome*
;
Humans
7.A Case of Congenital Dislocation of the Knee.
Seung Geun LIM ; Woo Jin KWON ; Sun Ki LEE ; Jae Ho HYUN ; Jin PARK ; Chun Hee WON ; Young Woo KIM
Korean Journal of Perinatology 1998;9(2):175-179
Congenital dislocation of the knee is very rare skeletal deformity and was firstly described by Chatelaine in 1822. Since then there have been a few number of case reports and some series discussing the etiology and treatment. The tibia is displaced anteriorly in relation to the femur. It is generally subdassified as simple hyperextention, subluxation, and dislocation depending on the degree of the joint displacement and the severity of disease. Early gentle manipulation and serial splintage or plaster cast are recommended for treatment and were successful in the majority except the case of quadriceps contrarture or late correction. The authors experienced one case of congenital dislocation of the right knee and brief review of the related literatures was made.
Casts, Surgical
;
Congenital Abnormalities
;
Dislocations*
;
Femur
;
Joints
;
Knee*
;
Tibia
8.Clinical and Neuroimaging Features of Moyamoya Disease.
Oh Young KWON ; Ki Jong PARK ; Sung Chul JEON ; Byeong Hoon LIM
Journal of the Korean Neurological Association 1998;16(4):432-438
BACKGROUND: Moyamoya disease is a chronic cerebrovascular disorders in which stenosis of the major arteries of the circle of Willis at the base of the skull progresses to occlusion. We observed two kinds of collateral pathways from the extracranial to the intracranial arteries. Also we evaluated clinlcal and neuroimaging features of moyamoya disease to give on aid in diagnosis. METHODS: We analysed 17 patients with moyamoya disease through the medical record and neuroimaging (conventional angiography and/or MR angiography) review. Six out of 17 patients were children(< OR =15 years) and the other 11 patients were adults(15 years). There were 8 males and 9 females. RESULTS: In our result, moyamoya disease was more common in the adult. There was bimodal age distribution, so average age of onset in children was 8-year-old and in adult 37-year-old. Common clinical features are seizure (66%), TIA (17%), and psychotic behavior (17%) in childrens and hemorrhages (73%), infarction (18%), seizures (9%) in adults. According to angiographic staging classification of Suzuki et al. (1967), our cases showed distribution of stage I (13%), stage II (8.8%), stage III (65.3%), stage IV (4.3%), stage V (4.3%), stage VI (4.3%). In collateral vessels of moyamoya disease, there were 7 cases of ethmoidal moyamoya, 3 of vault moyamoya and 1 of mixed form. It is interesting that there were five cases of unilateral moyamoya disease and one case had pseudoaneurysm. CONCLUSION: According to our results, we may say that seizures are common in the children and hemorrhages are in the adult. Unilateral moyamoya were mainly occurred in the adult. Ethmoidal collaterals were common among collaterals and stage III had a more cases than others in our neuroimaging data. These clinical and neuroimaging data may help interpretation and diagnosis of moyamoya disease.
Adult
;
Age Distribution
;
Age of Onset
;
Aneurysm, False
;
Angiography
;
Arteries
;
Cerebrovascular Disorders
;
Child
;
Circle of Willis
;
Classification
;
Constriction, Pathologic
;
Diagnosis
;
Female
;
Hemorrhage
;
Humans
;
Infarction
;
Male
;
Medical Records
;
Moyamoya Disease*
;
Neuroimaging*
;
Seizures
;
Skull
9.A Family of Hereditary Olivopontocerebellar Atrophy (Menzel type OPCA, OPCA III with retinal degeneration).
Seung Kil LIM ; Il Nam SEONWOO ; Ki Hwan KIM ; Oh Woong KWON ; Jung HO SEO
Journal of the Korean Neurological Association 1984;2(1):77-83
This is a case report of the familial olivo-ponto-cerebellar atrophy (Menzel type OPCA, OPCA III with retinal degeneration). The patient is a 37 year-old male with 5 years history of slowly progressive cerebellar ataxia, dysarthria, visual change, horizontal nystagmus and signs of pyramidal dysfunction. The CT brain scan shows significant atrophy of brain stem and cerebellum with dilatation of cisterns. His younger sister, also, has similar clinical manifestations and radiological abnormalities, but mild. By history, his mother who died at 47 years of her age looked like to have same kind of chronic disease.
Adult
;
Atrophy
;
Brain
;
Brain Stem
;
Cerebellar Ataxia
;
Cerebellum
;
Chronic Disease
;
Dilatation
;
Dysarthria
;
Humans
;
Male
;
Mothers
;
Nystagmus, Pathologic
;
Olivopontocerebellar Atrophies*
;
Retinaldehyde*
;
Siblings
10.A case of tracheo-bronchial amyloidosis.
Sung Woon KWON ; Yong Kyun KIM ; Kwang Ho JUNG ; Dong Soon KIM ; Woo Ki JEON ; Yeon Lim SUH
Korean Journal of Medicine 1993;45(5):690-695
No abstract available.
Amyloidosis*