Numerous cicatrizing and granulomatous diseases that simultaneously involve choroid, retina and their intervening Bruch's membrane may cause choroidoretinal vascular anastomoses. Anastomoses at capillary level and in neovascular granulomatous tissue are probably not uncommon under these and related circumstances, but choroidal connections to large-caliber segments of otherwise normal retinal arterioles and venules are unusual. We retrospectively studied 44 eyes of 44 patients with choroidal ruptures after blunt trauma. Of 44 choroidal ruptures, three patients had chorioretinal ruptures and choroidoretinal vascular anastomoses. This report describes three cases of large-caliber choroidoretinal anastomoses after chorioretinal ruptures.

No abstract available.
Infant, Newborn ; Meconium Aspiration Syndrome

PURPOSE: To determine whether acute or subacute attack influences the peripapillary atrophy in patients with primary angle-closure glaucoma (PACG). METHODS: Thirty-three eyes with PACG that had an acute or subacute attack (symptomatic PACG group) and 30 eyes with chronic PACG that had no attack (asymptomatic chronic PACG group) were studied. The rim/disc area ratio were matched in both groups. There were no statistically significant differences in the age, sex, refractive error, optic disc area, and visual field mean deviation between the two groups. RESULTS: Nineteen of 33 eyes (57.6%) with symptomatic PACG group and 20 of 30 eyes (66.7%) with asymptomatic chronic PACG group had zone beta. The mean zone beta/disc area ratio was 0.31 in symptomatic PACG group and was 0.52 in asymptomatic chronic PACG group. There were no statistically significant differences regarding the prevalence of zone beta (P=0.63) and the zone beta/disc area ratio (P=0.09) between the two groups. CONCLUSIONS: These findings suggest that the peripapillary atrophy in PACG is almost independent of acute or subacute attack.
Atrophy* ; Glaucoma, Angle-Closure* ; Humans ; Prevalence ; Refractive Errors ; Visual Fields

The efficacy and safety of mitomycin C(MMC) trabeculectomy was tested in patients with uncomplicated glaucoma(low-risk group) and the result was compared with that in patients with refractory glaucoma(high-risk group). Subjects included 37 eyes of 26 consecutive patients in low-risk group and 36 eyes of 26 patients in high-risk group. The mean preoperative IOP was 32.9 +/- 9.7 mmHg and 31.9 +/- 8.7 mmHg, respectively(p=1.45). The mean number of preoperative medications was 2.8 +/- 0.8 and 2.0 +/- 0.9, respectively(p<0.05). MMC(0.25 mg/ml or 0.5 mg/ml) was applied between Tenon's capsule and the sclera during trabeculectomy for 3 minutes in low-risk group, for 5 minutes in high-risk group. Scleral-flap was closed with tight releasable sutures. Eyes followed longer than 3 months were included(mean of 14.1 +/- 8.0 months vs 11.9 +/- 6.8 months, p=0.23). The low-risk group had better postoperative results including: a lower IOP at last follow-up(13.7 +/- 3.2 vs 17.2 +/- 8.4 mmHg, p=0.02), a better success rate(94% vs 83% with or without medications, p=0.23: 83% vs 55% without medications, p=0.02), a lower postoperative need for glaucoma medications(0.2 +/- 0.4 vs 0.6 +/- 08, p=0.005). Overall complications were similar between both groups. One of 37 eyes(3%) in the low-risk group developed a hypotony(p=0.51) and one of 36 eyes(3%) in the high-risk group developed a hypotony maculopathy(p=0.49). This study suggests that MMC trabeculectomy with tight releasable scleralflap sutures is safe and effective in controlling IOP not only in refractory glaucoma but also, more successfully, in uncomplicated glaucoma.
Glaucoma* ; Humans ; Mitomycin* ; Sclera ; Sutures ; Tenon Capsule ; Trabeculectomy*

We have investigated the clinical response of 12 patients with erythrodermic psoriasis to therapy with etretinate. Initial dosage of etretinate was 20-60mg/day. The time for complete disappearance of scales averaged 19.9 days. In 10 of 12 patients(83.3%) satisfactory results were obtained after 2 to 11 months of treatment. Cheilitis was the most common side effect. Three patients had mild elevation of blood lipids, which was corrected by dose reduction. Remission period, of ten patients who showed good result, averaged 4.2 months.
Acitretin* ; Cheilitis ; Etretinate* ; Humans ; Psoriasis* ; Weights and Measures

The aim of this study was to compare optic disc size obtained using the two methods Color polaroid photographs of optic disc of 130 normal subjects and 174 patients with glaucoma were evaluated by means of computeraided morphometry. In the first method, the optic disc size were calculated by applying the modified formula of an ellipse, where area=pi/4xthe horizontal diameterxthe vertical diameter. In the second method, we obtained optic disc size [] using the twelve radii that were measured every 30 degrees. Magnification effects of the eye and camera were corrected in the two methods. The measurements of the optic disc area(2.49mm2), cup area(1.01mm2) and neuroretinal rim area (1.49mm2) by the first method were significantly(P<0.003, Wilcoxon signed -rank test) different from the measurements by the second method(2.48mm2, 1.03mm2, 1.45mm2, respectively) (the average difference; 0.05+/-0.05mm2, 0.05+/-0.05mm2, 0.07+/-0.06mm2,respectively). The mean error for the neuroretinal rim area was 4.2+/-3.3% in the normal group and 7.5+/-8.5% in the glaucoma group(P=0.005). It increased with decreasing neuroretinal rim area and increasing visual field defects. Thus the magnification corrected measurements of the horizontal and vertical diameters and the modified formula of an ellipse can be used for a quick approximate estimation of the optic disc size, but cannot replace more accurate method of optic disc measurements using twelve radii.
Glaucoma ; Humans ; Visual Fields

PURPOSE: To identify the risk factors associated with false negative findings of optical coherence tomography (Stratus OCT) in patients with photographic localized retinal nerve fiber layer (RNFL) defects. METHODS: Twenty-four patients with preperimetric glaucoma and 173 patients with perimetric glaucoma, all with localized RNFL defects were included in the present study. The patients were divided into 2 groups according to the presence or absence of detection of photographic defects by OCT. Gender, age, refractive error, diabetes, hypertension, central corneal thickness, type of glaucoma, mean deviation, pattern standard deviation, average RNFL thickness, disc area, and photographic RNFL defect related variables (location, number, and angular width) were compared between the 2 groups. Each variable was initially evaluated by univariate analysis and significant variables (p < 0.1) were included in the logistic regression analysis. RESULTS: Photographic RNFL defects were not detected by OCT in 51 (25.9%) of the 197 eyes. The angular locations and widths of RNFL defects by OCT were significantly correlated with those of RNFL defects by red-free RNFL photographs (Pearson correlation coefficient R = 0.98 and 0.64, respectively). Logistic regression analysis revealed the risk factors for false negative findings of OCT included average RNFL thickness (odds ratio = 1.106, 95% confidence interval [CI] = 1.057-1.156, p < 0.001) and angular width of defect (odds ratio = 0.929, 95% CI = 0.884-0.977, p = 0.004). CONCLUSIONS: This present study suggests that false negative findings of OCT in patients with photographic localized RNFL defects were associated with thicker RNFL thickness and smaller angular width of RNFL defect.
Eye ; Glaucoma ; Humans ; Hypertension ; Logistic Models ; Nerve Fibers ; Refractive Errors ; Retinaldehyde ; Risk Factors ; Tomography, Optical Coherence

To determine the optimum concentration of mitomycin C(MMC) in patients with refractory glaucoma undergoing trabeculectomy, we retrospectively examined 31 eyes of 22 patients with refractory glaucoma who underwent trabeculectomy with 0.25mg/ml MMC for 5 minutes. They were case matched with a group of 36 eyes of 28 patients who had undergone trabeculectomy with 0.5mg/ml MMC for 5 minutes by using age, gender, type of refractory glaucoma, preoperative intraocular pressure(IOP), and preoperative medications as variables. MMC was applied between the sclera and Tenon's capsule during trabeculectomy, and scleral flap was closed with tight releasable sutures. No statistically significant differences were found in mean IOP between the two groups at the one, three, six, and nine months postoperative periods. The mean follow-up was 9.3 months in the 0.25mg group and 9.8 months in the 0.5 mg group(p=0.70). At the last postoperative visit, 81%(25 eyes) in the 0.25mg group and 86%(31 eyes) in the 0.5mg group had an IOP less than 21mmHg with or without glaucoma medication(p=0.79). At the last postoperative visit, there were no statistically significant differences in mean IOP(17.2 +/- 8.6mmHg and 17.2 +/- 7.3mmHg, respectively, p=0.99), mean number of medications(0.6 +/- 0.9 and 0.5 +/- 0.7, respectively, p=0.77), and change in visual acuity(3 eyes and 6 eyes lost more than 2 lines of vision, respectively, p=0.75) between the two groups. The incidence of complications were similar between the two groups. Our data suggests similar efficacy and safety in trabeculectomy with 0.25 and 0.5mg/ml MMC for 5 minutes.
Follow-Up Studies ; Glaucoma* ; Humans ; Incidence ; Intraocular Pressure ; Mitomycin* ; Postoperative Period ; Retrospective Studies ; Sclera ; Sutures ; Tenon Capsule ; Trabeculectomy*

The purpose of this study is to compare the efficacy and safety of 0.25 and 0.5mg/ml of mitomycin C(MMC) on the outcome of glaucoma filtration surgery in eyes undergoing primary trabeculectomy. Twenty-eight eyes of 20 patients with primary open-angle glaucoma or primary angle-closure glaucoma, who underwent primary trabeculectomy with 0.25mg/ml MMC for 3 minutes were compared with a demographically similar group of 31 eyes of 22 patients with primary open-angle glaucoma or primary angle-closure glaucoma, who had undergone primary trabeculectomy with 0.5mg/ml MMC for 3 minutes. MMC was applied between the sclera and Tenon's capsule during trabeculectomy, and scleral flap was closed with tight releasable sutures. The mean preoperative intraocular pressure was 35.2 +/- 9.3mmHg in the 0.25mg group and 32.1 +/- 9.2mmHg in the 0.5mg group(p=0.21, Student's unpaired t-test). The mean number of preoperative medications was 2.7 +/- 0.9 and 2.7 +/- 0.8(p=0.92, Mann Whitney U test), respectively. No statistically significant differences were found in mean intraocular pressures between the two groups at the three. six, and nine months postoperative periods. The mean follow-up was 9.2 months in the 0.25mg group and 9.0 months in the 0.5mg group(p=0.82, Student's unpaired t-test). At the last postoperative visit. 89%(25 eyes) in the 0.25mg group and 97%(30 eyes) in the 0.5mg group had an intraocular pressure less than 21mmHg with or without glaucoma medication(p=0.50, Fisher exact test). The mean intraocular pressures were 16.0 +/- 6.9mmHg and 13.6 +/- 3.6mmHg, respectively (p=0.10, Student's unpaired t-test). The 0.25mg group received an average of 0.5 medications for IOP control, and the 0.5mg group received an average of 0.2 medications(p=0.32, Mann Whitney U test). The postoperative visual outcome of the two groups did not differ significantly(p=0.27, Fisher exact test). There was no significant difference in complications between the two groups. Hypotony developed in one eye in the 0.5mg group. These results suggest that using 0.25 and 0.5mg/ml MMC for 3 minutes in primary trabeculectomy yields similar results in terms of efficacy and safety.
Filtering Surgery ; Follow-Up Studies ; Glaucoma* ; Glaucoma, Angle-Closure ; Glaucoma, Open-Angle ; Humans ; Intraocular Pressure ; Mitomycin* ; Postoperative Period ; Sclera ; Sutures ; Tenon Capsule ; Trabeculectomy*

Favus is a chronic dermatophyte infection of the scalp presented by thick yellow crusts within the hair follicles which leads to scarring alopecia. Favus is associated with poor hygiene and malnutrition so that it is seen almost exclusively in Africa, the Middle East and parts of South America with abruptly decreased incidence nowadays. The last report referring favus was published in 1996 in Korea, which might have historical significance. Herein, we report favus diagnosed in siblings in 1979.
Africa ; Alopecia ; Arthrodermataceae ; Cicatrix ; Hair Follicle ; Humans ; Hygiene ; Incidence ; Korea ; Malnutrition ; Middle East ; Scalp ; Siblings* ; South America ; Tinea Favosa*